Clinical trials: Low Cost
HIV-1-infection
Kenya HIV Self-Testing in PrEP Delivery
In a three-arm, randomized trial, the investigators will test the use of HIV-1 self-testing to decrease the frequency and burden of clinic visits for PrEP while resulting in equivalent PrEP adherence and HIV testing.
- Trial name
- NCT03593629
- Testing
- 6-month PrEP + blood-based HIV self-test, 6-month PrEP + oral fluid HIV self-test
- Where
- Kenya
- Volunteers
- 790 people, healthy volunteers welcome
- Sponsor
- University of Washington
Child Malnutrition
Developing Low-Cost Universal Malnutrition Screening for Low Income Countries - the MAMMS Trial
Acute malnutrition affects 52 million children, costs $2.1 trillion globally, and contributes to 45% of deaths among children under five years of age.
- Trial name
- NCT03967015
- Testing
- Maternal Administered Malnutrition Monitoring System (MAMMS)
- Where
- 3 sites in Kenya
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Washington
Depression
LTP Plus Dads-Partner Inclusive Intervention for Depressed Fathers in Pakistan
The aim of this study is to support and equip fathers and mothers with cognitive behavioral tools and knowledge about child development to be effective in their role as co-parent and partner, leading to improvement in paternal…
- Trial name
- LTP+Dads (NCT05036720)
- Testing
- LTP+Dads, LTP+ Optional mother component
- Where
- Pakistan
- Volunteers
- 2,884 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Living and Learning
Fibula / Surgery, Surgical Flaps
Novel Application of a Low-cost Alternative to Patient Specific Implants (PSI) in Mandibular Free Fibula Flap Reconstruction by Reverse Engineering of Stock Plates: A Pilot Validation Study
Stock reconstruction plates have been used for decades and represent a tried-and-true alternative to custom plating. Stock plates are readily available, are cost effective, and can be accurately bent before surgery, particularly…
- Conditions
- Fibula / Surgery, Surgical Flaps, Computer-Aided Design, Mandibular Reconstruction* / Methods
- Trial name
- NCT05672056
- Testing
- Computer guided placement of a stock plate pre-bent on a 3D printed model
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infant Development
A Community Based Implementation of a Toolkit and Parenting Program for Improving Brain Development in Newborns
The investigators propose to develop and test the efficacy of a low cost evidence based toolkit aimed at improving brain development among newborns a rural setting of Pakistan.
- Trial name
- NCT02290756
- Testing
- Parenting Program, Low cost evidence based toolkit
- Where
- Pakistan
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Child Malnutrition
Leveraging an Existing Large-scale Safe Water Program to Deliver Nutrition Messages at a Low Marginal Cost
The investigators are seeking to overcome the dual challenges of under-nutrition and diarrhea using an existing safe water supply platform to deliver nutrition information to targeted groups in Western Kenya.
- Trial name
- NCT02427945
- Testing
- Provision of information on safe water, Provision of information on safe water and child nutrition
- Where
- Kenya
- Volunteers
- 1,671 people, healthy volunteers welcome
- Sponsor
- Marcos Vera Hernandez
Optical Coherence Tomography of Retina, Alzheimer Disease
Comparative Study of High Performance Low-Cost Optical Coherence Tomography (Stage 1B, 2 and 3)
The purpose of this study is to complete performance testing of our custom optical coherence tomography (OCT) device to verify it can deliver retinal images of similar quality to a commercial OCT device.
- Trial name
- NCT07425106
- Testing
- retinal imaging with low-cost OCT-a/LCI device
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Duke University
Postpartum Hemorrhage
Ghana: The Barriers and Facilitators of Scaling up the Ellavi UBT for Postpartum Hemorrhage
The purpose of this implementation science study is to generate evidence that informs the successful uptake and adoption of the Ellavi UBT within Ghana's PPH management programs.
- Trial name
- NCT05340777
- Testing
- Training Obstetric staff on Ellavi UBT
- Where
- 3 sites in Ghana
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- PATH
Sickle Cell Disease, Sickle Cell Trait
Evaluation of Low-cost Techniques for Detecting Sickle Cell Disease and β-thalassemia in Nepal and Canada
Sickle cell disease (SCD) is an inherited blood disorder associated with acute illness and organ damage. In high resource settings, early screening and treatment greatly improve quality of life.
- Conditions
- Sickle Cell Disease, Sickle Cell Trait, Beta-Thalassemia, Sickle Cell-Beta Thalassemia
- Trial name
- NCT05506358
- Testing
- High performance liquid chromatography, Automated sickling test, HbS solubility test
- Where
- 3 sites in Canada, Nepal
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Obesity
Trial of Provider-to-Patient Interactive Voice Response (IVR) Calls to Improve Weight Management in Community Health Centers (CHCs)
This study will test the effect of provider to patient interactive voice response (IVR) calls in local Community Health Centers within a weight management program.
- Trial name
- IVR (NCT01131143)
- Testing
- Provider Voice, Generic Voice
- Where
- United States
- Volunteers
- 1,228 people, healthy volunteers welcome
- Sponsor
- Indiana University
Seizures, Epilepsy
Ear-Seizure Detection (EarSD) Study
The proposed study is an investigator-initiated study that aims to measure the accuracy of a wearable seizure detection and prediction device (Ear-Seizure Detection Device (EarSD)) by simultaneous recording with conventional…
- Trial name
- EarSD001 (NCT06598189)
- Testing
- Ear-SD, Electroencephalogram
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Felicia Chu
Surgical Procedure, Unspecified
Bucatini Pasta, Japanese Shirataki Konjac Noodles, and Artificial Vessels: In Search of the Ideal Low-cost Vessel Simulator for Microsurgical Education
The aim of this study is to assess the strengths and weaknesses of training models that are accessible, reproducible, and geared toward new learners.
- Trial name
- NCT07006766
- Testing
- Microsurgical Training Models
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Covid19, SARS-CoV2 Infection
Reducing Spread of COVID-19 in a University Community Setting: Role of a Low-Cost Reusable Form-Fitting Fabric Mask
The primary aim of the proposed research is to test the role of a newly developed reusable form-fitting fabric mask in reducing the spread of COVID-19 in a community setting comprising undergraduate students living in dormitories…
- Trial name
- NCT04979858
- Testing
- Focal Mask
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Pain
Evaluating VR Therapy Using Cold Pressor Test
This study is testing whether or not low-cost, virtual reality (VR) headsets for mobile phones can be used as a potential distractor from pain and thus would have clinical applications as a low-cost, non-pharmaceutical method to…
- Trial name
- NCT03268863
- Testing
- Virtual Reality, Cold Pressor
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Janet Vittone
Cervical Cancer
Cervical Cancer Screening Study in Brazil
Objectives: Primary Objective: To perform a pilot clinical study to test multi-modal optical imaging for detection of cervical neoplasia in Brazil.
- Trial name
- NCT02335372
- Testing
- Wide-Field White Light Imaging, Acetic Acid, Proflavine Solution
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Diarrhea, E.Coli Infections
Trial of Low-cost Microbiological Water Test Kits
The present study is a cluster randomized control trial of low-cost microbiological water test kits in rural and peri-urban communities in the Kanpur region of Uttar Pradesh, India.
- Trial name
- NCT03021434
- Testing
- Community and household water safety education sessions, Household-specific water quality information, Low-cost microbiological water test kits
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Refractive Errors
Investigation of the Accuracy of a Low-cost, Portable, Autorefractor to Provide Well-tolerated Eyeglass Prescriptions
At the Aravind Eye Hospital (AEH) in Madurai, India, patients ages 18-40 receiving treatment for refractive error who choose to enroll in the study will be evaluated using subjective refraction and objective refraction, by way of…
- Trial name
- NCT03615612
- Testing
- QuickSee refractive error assessment + glasses
- Where
- India
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Spinal Cord Injuries
Validity and Reliability of a Low-cost Chair Dynamometer
In part 1 of the study, fourteen able-bodied individuals will undergo maximal, voluntary contraction (MVC) test of the lower limbs in two dynamometers.
- Trial name
- NCT04291924
- Testing
- Dynamometry
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Spinal Cord Injury Centre of Western Denmark
Open Access, Medical Devices
Validation of a High-Quality Low-Cost Open-Source Electrocardiograph
The high price of electrocardiograph (ECG) devices - with most hospital-grade devices costing thousands of dollars - is one of the barriers to access of this vital technology.
- Conditions
- Open Access, Medical Devices, Low Cost, Electrocardiograph
- Trial name
- NCT04209062
- Testing
- Medical device validation
- Where
- Canada
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Ovarian Cancer
Connecting Families to Overcome Ovarian Cancer
This study tests a multi-component, low cost, message-based communication outreach intervention to engage ovarian cancer survivors and their at-risk relatives in considering cancer genetic services.
- Trial name
- NCT04927013
- Testing
- Message-based Outreach Intervention for Survivors, Standard Outreach for Survivors, Message-based Outreach Intervention for Close Relatives
- Where
- United States
- Volunteers
- 2,331 people, healthy volunteers welcome
- Sponsor
- Emory University