Clinical trials: Low-flow Anesthesia
Tympanoplasty, Myringoplasty
NLR and Sevoflurane Use in Ear Surgeries: Flow Comparison
This retrospective study aims to compare the effects of low-flow and high-flow anesthesia techniques on intraoperative hemodynamics, neutrophil-to-lymphocyte ratio (NLR), and postoperative outcomes in patients undergoing…
- Conditions
- Tympanoplasty, Myringoplasty, Neutrophil-to-Lymphocyte Ratio, Low-flow Anesthesia
- Trial name
- ANFLUX (NCT07064642)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Eda KAZANÇ ÖZDEN
Anesthesia
Low Fresh Gas Flow in Prone Position
Low flow anesthesia in the prone position was safe in terms of systemic hemodynamics and did not reduce cerebral oxygenation compared to normal flow.
- Trial name
- NCT05462327
- Testing
- Low Fresh Gas Flow in Prone Position, Normal Fresh Gas Flow in Prone Position
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Perfusion Index, Low-Flow Anesthesia
Perfusion Index in Pediatric Low-Flow Anesthesia
This study aims to evaluate changes in perfusion index (PI) in pediatric patients undergoing elective surgery under low-flow anesthesia.
- Conditions
- Perfusion Index, Low-Flow Anesthesia, Postoperative Recovery
- Trial name
- NCT06967675
- Testing
- Low-Flow Anesthesia (LFA)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istinye University
Anesthesia
Different Low-flow Sevoflurane Anesthesia Techniques
After reaching 1 MAC level with 4 lt / min fresh gas flow and 2.5% sevoflurane concentration in the initial stage in 35 patients, anesthesia maintenance will be continued with 0.5 lt / min fresh gas flow and 2 -4% sevoflurane…
- Trial name
- NCT04743193
- Testing
- 2.5 %sevoflurane, 8% sevoflurane low flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli Derince Education and Research Hospital
Anesthesia
Evaluation of Different Methods for Preoxygenation
The goal of this randomised cross-over study is to compare pre-oxygenation using a standard nasal cannula to pre-oxygenation using humidified high-flow nasal oxygen and a tight-fitting facemask in adult volunteers with a BMI…
- Trial name
- NCT05839665
- Testing
- Humidified high-flow nasal oxygen, Standard nasal cannula, Facemask
- Where
- 2 sites in Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Malin Jonsson Fagerlund
Post-Dural Puncture Headache, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Predictive Value of ONSD and NIRS for PDPH
Currently, there is no reliable and effective method available in clinical practice to predict the development of PDPH. Early prediction and prevention of PDPH would reduce the incidence of postoperative complications, thereby…
- Trial name
- NCT07729449
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ordu University
Cardiac Output, Low, Coronary Arterial Disease
Post-Induction Low Cardiac Output Syndrome in Coronary Artery Bypass Graft Surgery
Hemodynamic change after induction of general anesthesia is usually judged from mean arterial pressure. Pressure, however, is a surrogate for flow, and the two can separate: cardiac output may fall while arterial pressure remains…
- Conditions
- Cardiac Output, Low, Coronary Arterial Disease, Anesthesia, General
- Trial name
- PiLCOs (NCT07810621)
- Testing
- routine clinical monitoring, observed only
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Ataturk University
Anaesthesia
Sevoflurane vs. Isoflurane for Low-Flow General Anaesthesia for Abdominal Surgery
Two groups of patients are going to have abdominal surgery with low-flow general anaesthesia. Group A (sevoflurane group, experimental group) will use volatile anaesthetic sevoflurane.
- Trial name
- NCT00521612
- Testing
- sevoflurane, isoflurane
- Where
- Croatia
- Volunteers
- 82 people
- Sponsor
- General Hospital Dubrovnik
Delirium - Postoperative, Low Flow Anesthesia
Low- vs. Normal-Flow Anesthesia and Delirium After Hip Fracture in the Elderly
The aim of this study is to investigate the relationship between low-flow and normal-flow anesthesia techniques and the development of postoperative delirium in elderly patients undergoing surgery for hip fracture.
- Conditions
- Delirium - Postoperative, Low Flow Anesthesia, Elderly Patients (>65 Years), Hip Surgery
- Trial name
- NCT06973967
- Testing
- delirium
- Volunteers
- 128 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Intracranial Hypertension
Optic Nerve Sheath Diameter in Low-flow and Normal-flow Rate Anesthesia
Laparoscopic cholecystectomy is one of the regularly performed laparoscopic surgical procedures. It resulted in shorter hospital stays, improved cosmetic outcomes, and reduced bleeding and pain.
- Trial name
- NCT05946200
- Testing
- Low flow technique in general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Konya City Hospital
Low Flow Anesthesia
Low-Flow Anesthesia Without Wash-in: Effects on Oxygenation and Depth of Anesthesia
This study aims to evaluate whether adjusting the fresh gas flow rate to low-flow immediately after intubation, without performing a wash-in, is a reliable approach with respect to depth of anesthesia and oxygenation.
- Trial name
- NCT07534839
- Testing
- Initiation of low-flow anesthesia without wash-in following intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Erzincan Binali Yildirim Universitesi
Anesthesia
Desflurane and Sevoflurane Minimal Flow Anesthesia on Recovery and Anesthetic Depth
Minimal flow anesthesia has economic and environmental advantages in addition to providing earlier recovery following general anesthesia.
- Trial name
- NCT05024084
- Testing
- Minimal flow anesthesia (fresh gas flow <0.5 l/min) using Sevoflurane, Minimal flow anesthesia (fresh gas flow <0.5 l/min) using Desflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Ufuk University
Oxidative Stress, Anesthesia
Comparison of Total Oxidant and Total Antioxidant Capacities in Low-Flow and High-Flow General Anesthesia
The goal of this observational study is to determine whether low-flow anesthesia has a positive contribution to the total oxidant/antioxidant balance.
- Trial name
- NCT05590312
- Testing
- general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Duzce University
COVID 19
Use of the Nasal Cannula During COVID-19
The objective of this investigation is to determine the incidence of the use of the low flow nasal cannula in suspected or confirmed cases with Covid-19
- Trial name
- NCT04376580
- Where
- Argentina
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tiva Group
Morbid Obesity, Anesthesia Awareness
Comparison of Low Versus Normal Flow Anesthesia on Cerebral Oxygenation and Bispectral Index in Morbidly Obese Patients
Obesity is a chronic disease that affects quality and duration of life negatively. It's not clearly known the effects of low flow anesthesia on cerebral oxygenation with high-risk morbidly obese patients.
- Conditions
- Morbid Obesity, Anesthesia Awareness, Anesthesia Complication
- Trial name
- CerOxygen (NCT03438734)
- Testing
- Regional cerebral oxygen saturation, Bispectral Index (BIS)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Inonu University
Low-flow Anesthesia, Hemodynamics
Low-Flow Anesthesia and Open-Heart Surgery
Low-flow anesthesia (LFA) is a technique in which at least 50% of the exhaled air, after carbon dioxide absorption, is mixed with a certain amount of fresh gas and returned to the patient during the next inspiration. In 1974, R.
- Conditions
- Low-flow Anesthesia, Hemodynamics, Open-heart Surgery
- Trial name
- NCT07040735
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Çağrı Özdemir
Anesthesia
The Effect of Blood Carboxyhemoglobin Levels on NF-kB, NRF2 and PGC-1α During Low-flow and Normal-flow Anesthesia
Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that exerts diverse biological effects across tissues and organs.
- Trial name
- NCT07352826
- Testing
- low-flow anasthesia, Normal akımlı anestezi
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ataturk Training and Research Hospital
Laparoscopic Cholecystectomy
Low Flow and High Flow Anesthesia on Thiol-Disulfide Homeostasis and IMA in Laparoscopic Cholecystectomy Surgery
Comparison of the Effects of Low Flow and High Flow Anesthesia on Thiol-Disulfide Homeostasis and Ischemia Modified Albumin in Laparoscopic Cholecystectomy Surgery In this study, our aim is to compare the effects of Low Flow and…
- Trial name
- İMA (NCT04926480)
- Testing
- low and high flow Anesthesia
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Carbon Monoxide Exposure
The Effect of Blood Carboxyhemoglobin Levels on Total Antioxidant (Tas), Total Oxidant(Tos), Hypoxia Inducible Factor-1a (hif1a) During Low-flow and Normal-flow Anesthesia
In contrast to toxic CO concentrations, low-dose CO acts as a signaling molecule and can exert many complex cytoprotective effects.
- Trial name
- NCT05661045
- Testing
- low-flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Ataturk Training and Research Hospital
Low Flow Anesthesia, Normal Flow Anesthesia
Comparison of Low and Normal Flow Anesthesia in Robotic Assisted Radical Prostatectomy
Robot-assisted laparoscopic radical prostatectomy has gained increasing popularity compared to open radical prostatectomy with its advantages such as low blood loss, reduced blood transfusion rate, low complication rate, and…
- Conditions
- Low Flow Anesthesia, Normal Flow Anesthesia, Robotic Surgery
- Trial name
- NCT05517551
- Testing
- robotic assisted radical prostatectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent