Clinical trials: Lower Extremity Muscle Strength
Anterior Cruciate Ligament Injuries, Knee Injuries
Effects of Early Rehabilitation Using Blood Flow Restriction and/or Surface Electromyography Biofeedback on Quadriceps Activation and Strength After Anterior Cruciate Ligament Reconstruction: A Multicenter Randomized Controlled Trial
Many patients experience quadriceps inhibition after anterior cruciate ligament (ACL) reconstruction, delaying strength recovery, hindering return to sport, and potentially increasing the risk of re-injury.
- Conditions
- Anterior Cruciate Ligament Injuries, Knee Injuries, Muscle Weakness
- Trial name
- NCT07145606
- Testing
- Standard Rehabilitation, Blood Flow Restriction (BFR) Training, sEMG Biofeedback
- Where
- 4 sites in France, Switzerland
- Volunteers
- 200 people
- Sponsor
- Haute Ecole ARC Sante
Gluteus Medius Muscle Strength, Lateral Hip Pain
The Utilization of a Shoe Insert on Individuals With Unilateral Greater Trochanteric Pain Syndrome on Single Leg Stance, Biomechanics, and Pain Intensity
We hypothesize that the addition of a unilateral neutral shoe insert combined with standard physical therapy (PT+SI) will have greater improvements in pain and function at 12 weeks and 6 months compared to physical therapy with…
- Conditions
- Gluteus Medius Muscle Strength, Lateral Hip Pain, Greater Trochanter Pain Syndrome, Gluteus Medius Tendinopathy, Gluteus Minimus Tendinopathy
- Trial name
- NCT06891001
- Testing
- Unilateral neutral shoe insert, Bilateral Shoe Insert, Physical Therapy
- Where
- United States
- Sponsor
- Mayo Clinic
Physical Performance, Leg Muscle Mass
Lower-Limb Muscle Mass and Cardiovascular and Muscular Performance in Males and Females
The aim of this study will be to examine the relationship between leg muscle mass and muscle strength, aerobic capacity, anaerobic power, and jumping performance in young adults.
- Conditions
- Physical Performance, Leg Muscle Mass, Muscle Strength, Aerobic Capacity
- Trial name
- NCT07440615
- Testing
- Physical Performance Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Uludag University
Healthy
Effects of Heavy-load Resistance Training
The study aims to investigate effects of 8-weeks of heavy-load resistance training on mechanical muscle function and functional performance in elite female team handball players from the Danish Women's Handball League.
- Trial name
- NCT06356935
- Testing
- RT, CON
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Healthy
Resistance Training With Blood Flow Restriction
Blood flow restriction associated with resistance training is suggested to potentiate increases in muscular strength and hypertrophy.
- Trial name
- NCT05863039
- Testing
- Blood flow restriction, Regular training type 1, Regular training type 2
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Aged, Muscle Strength
Strengthening in Functional Mobility of Active Elderly
Aging is characterized by functional losses among which, the related to mobility and balance may be highlighted. Regular physical activity, including muscle strengthening exercises, is beneficial to a healthy elderly.
- Trial name
- NCT02968030
- Testing
- Muscle strength
- Where
- Brazil
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Lislei Jorge Patrizzi
Pes Planus, Flatfoot
Peripheral Magnetic Stimulation of Foot Muscles: Effects on Medial Longitudinal Arch Height and Foot Muscle Strength in Adults With Flat Feet
This study examines the effects of repetitive peripheral magnetic stimulation (rPMS) on foot invertor muscle strength, morphology, and the height of the medial longitudinal arch (MLA) in individuals with flat feet.
- Conditions
- Pes Planus, Flatfoot, Posterior Tibial Tendon Dysfunction
- Trial name
- rPMS-Foot (NCT07237321)
- Testing
- Repetitive Peripheral Magnetic Stimulation (rPMS)
- Where
- 2 sites in Slovenia
- Volunteers
- 30 people
- Sponsor
- University of Ljubljana
Anterior Cruciate Ligament (ACL) Injury
The Influence of Demographic Parameters and ACL Injury on the Association Among Clinical, Functional and Biomechanical Parameters
This retrospective study aims at analysing demographics and clinical, functional and biomechanical outcomes in patients after ACL injury (conservative therapy and/or surgery) in patients of different ages and healthy controls.
- Trial name
- MechBRACE (NCT05644275)
- Testing
- Data collection (demographic, clinical, functional and biomechanical outcomes in patients after ACL injury (conservative therapy and/or surgery) in patients of different ages and healthy controls)
- Where
- Switzerland
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Anterior Cruciate Ligament Reconstruction Rehabilitation, Blood Flow Restriction (BFR) Training Effects
Effect of Blood Flow Restriction Rraining on Rehabilitation After Anterior Cruciate Ligament Reconstruction
Importance: Following anterior cruciate ligament reconstruction (ACLR), patients often experience quadriceps muscle weakness and atrophy, frequently leading to long-term complications.
- Trial name
- NCT07311031
- Testing
- Blood flow restriction training, Standard ACL rehabilitation
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital MAZ
Acute Neuromuscular Responses to Aerobic Exercise in Elite Youth Gymnasts
Acute Effects of Aerobic Exercise Intensity on Lower-Limb Muscle Strength and Power in Youth Gymnasts
This study investigates the acute effects of different aerobic exercise intensities on lower-limb muscle strength and power in elite male youth gymnasts.
- Trial name
- NCT07415395
- Testing
- High-Intensity Interval Training, Moderate-Intensity Continuous Training, Low-Intensity Steady-State Exercise
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Chaoran Han
Anterior Cruciate Ligament Rupture
Hamstring Muscle Strength After ACL Hamstring Reconstruction
Anterior Cruciate Ligament (ACL) reconstructions using hamstring grafts can be performed using one or two hamstring grafts, the semitendinosus (ST) tendon only, or both the semitendinosus and gracilis (ST/G) tendon.
- Trial name
- HAMSTRING (NCT05464485)
- Testing
- ACL hamstring reconstructions using semitendinosus (ST) tendon only, ACL hamstring reconstructions using semitendinosus and gracilis (ST/G) tendon
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Isala
Stroke
Comparative Effects of PNF and mCIMT on Lower Limb Function in Patient With Stroke
Stroke, which is frequently characterized by weakness, poor balance, and decreased mobility that impede independence in everyday activities, has been identified as a major cause of long-term impairment globally.
- Trial name
- NCT07331714
- Testing
- PNF, mCIMT
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Diabetic Foot, Peripheral Neuropathy With Type 2 Diabetes
The Effects of Different Exercises on Tissue Mechanics, Strength and Neuropathy Symptoms in Type 2 Diabetes Patients
To examine the effects of aerobic exercise and foot exercises in addition to aerobic exercise on lower extremity distal tissue mechanics, muscle strength and neuropathy symptoms in type 2 diabetics with peripheral neuropathy.
- Trial name
- NCT05422235
- Testing
- Routine Medical Treatment, Aerobic Exercise, Aerobic Exercise+ Foot-Related Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Anterior Cruciate Ligament Rupture
BFRT in Adolescents After ACL Reconstruction
This is an interventional study that will examine effects of blood flow restriction training (BFRT) in adolescents aged 12-18 after anterior cruciate ligament reconstruction surgery (ACLR).
- Trial name
- NCT04390035
- Testing
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Plyometric Exercise, Sedentary Behavior
Efficiency in 4-week Plyometric Training: Lower Limb Improvement in Sedentary Adults
The goal of this clinical trial is to compare the effects of different volumes of plyometric training on lower limb muscle strength, power, and muscle activity in sedentary individuals.
- Trial name
- NCT05928130
- Testing
- plyometric training protocol
- Where
- Chile
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rodrigo Lizama Perez
Diabetic Neuropathies, Peripheral Nervous System Diseases
Effect of Physical Therapy in Improving the Health of Patients With Diabetic Peripheral Neuropathy
People with diabetes can have nerve damage in their extremities (peripheral neuropathy), and this can lead them to being less able to maintain their balance when they are standing, walking or performing complex movement tasks in…
- Trial name
- DPN-QoL (NCT02115932)
- Testing
- Strength & Balance Training
- Where
- Singapore
- Volunteers
- 143 people
- Sponsor
- National University Health System, Singapore
Children, Muscle Strength
Reliability and Validity of Strength Measurement of the Lower Limbs in Typically Developing Children
Reliability of isokinetic strength measurement of the knee in typically developing children has yet been studied and seems to be good.
- Conditions
- Children, Muscle Strength, Reproducibility of Results, Muscle Strength Dynamometer
- Trial name
- NCT04024592
- Testing
- Biodex System 4
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Ghent
Rheumatoid Arthritis
Effectiveness of Water Exercises on Isokinetic Muscle Strength
The interest in studying the impact of aquatic exercise on muscle strength of patients with rheumatoid arthritis came after publication of several studies that pointed to the potential benefit of exercise on the natural history…
- Trial name
- NCT01447264
- Testing
- Land exercises, Water exercises
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Hip Joint, Muscle Weakness
The Effect High Velocity Low Amplitude Hip Mobilization on Strength in Subjects With Lower Extremity Pathology
Introduction: Lower extremity weakness associated with musculoskeletal pathology can cause activity limitations. Physical therapy intervention in the form of exercise is commonly directed at improving muscular performance…
- Trial name
- NCT03115879
- Testing
- Hip mobilization, Hip manipulation simulation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Anterior Cruciate Ligament Injuries, Atrophy, Muscular
Bilateral Versus Unilateral Strength Training After ACLR
After rehabilitation completion, there remains large deficiencies between the operative (OP) and non-operative (NOP) limbs in lower-limb outcomes (e.g., size, strength, and function) and these deficits can persist for years.
- Conditions
- Anterior Cruciate Ligament Injuries, Atrophy, Muscular, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- BUST (NCT06032247)
- Testing
- Resistance exercise program- UL, Resistance exercise program- BL
- Where
- United States
- Sponsor
- University of Kansas