Clinical trials: Lower Extremity Pain
Knee Injuries
Trial Comparing BST-CarGel and Microfracture in Repair of Articular Cartilage Lesions in the Knee
This study will investigate whether the treatment of damaged cartilage in the knee with BST-CarGel will increase the amount and quality of cartilage repair tissue when compared with microfracture alone.
- Trial name
- NCT00314236
- Testing
- BST-CarGel with Microfracture, Microfracture without BST-CarGel
- Where
- 18 sites in Canada, South Korea and 1 more
- Volunteers
- 80 people
- Sponsor
- Piramal Healthcare Canada Ltd
Chronic Low Back Pain (CLBP)
How Osteopathic Treatment Affects the Leg and Foot in People With Low Back Pain
This pilot study will examine whether osteopathic manipulative treatment (OMT) can improve both physical and psychological aspects of chronic low back pain by focusing on the interconnected myofascial system of the back, legs…
- Trial name
- NCT07193212
- Testing
- Osteopathic Manipulative Treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Pain, Chronic, Sympathetic Disorder
Clinical Trial of Ultrasound Combined With Computed Tomography Guided Lumbar Sympathetic Ganglion Block
To evaluate the safety and efficacy of ultrasound combined with CT-guided sympathetic ganglion block for refractory pain caused by sympathetic neuropathy of the lower extremities.
- Conditions
- Pain, Chronic, Sympathetic Disorder, Ultrasound Therapy
- Trial name
- NCT04167956
- Testing
- ultrasound and CT
- Where
- China
- Volunteers
- 246 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Hip Fracture Surgery, Postoperative Pain Management
Comparison of Sacral Erector Spinae Plane Block and Supra-Inguinal Fascia Iliaca Block for Analgesia After Hip Fracture Surgery
This study compares the postoperative analgesic effectiveness of Sacral Erector Spinae Plane Block (SESPB) and Supra-Inguinal Fascia Iliaca Block (SIFIB) in patients undergoing hip fracture surgery.
- Conditions
- Hip Fracture Surgery, Postoperative Pain Management, Regional Anesthesia, Elderly Patients
- Trial name
- NCT07081867
- Testing
- Supra-inguinal Fascia Iliaca Block (SIFIB), Sacral Erector Spinae Plane Block (SESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Hip Injuries, Hip Fractures
Is the Rate of Early Mobilisation in Hip Fracture Patients Using Alfentanil Better Than Standard Opioid Analgesia?
Hip fracture injuries are linked with increased morbidity, frailty, and mortality risk. Studies have shown that in hip fracture surgery, early mobilisation confers better pain control, 30-day complication and mortality rates and…
- Conditions
- Hip Injuries, Hip Fractures, Pain, Post Operative Pain
- Trial name
- REHAB (NCT06212622)
- Testing
- Alfentanil, Oxycodone
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- NHS Lothian
Pain, Postoperative, Ankle Fracture Surgery
Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery
Addictive full-agonist opioids, like oxycodone and hydrocodone, are often used to treat pain after surgery. However, these full-agonist opioids can be very addictive.
- Conditions
- Pain, Postoperative, Ankle Fracture Surgery, Opioid Use Disorder, Opioid Dependence
- Trial name
- BAFA (NCT06949826)
- Testing
- Buprenorphine Transdermal System
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Jenna-Leigh Wilson
Patellofemoral Pain Syndrome
Utilizing the Trunk as a Proximal Lever to Strengthen the Hip Musculature and Alter Lower Extremity Function
Does a rotary based triplanar exercise intervention that utilizes the trunk as a proximal lever, strengthen the hip and alter dynamic LE alignment in running females?
- Trial name
- NCT03285464
- Testing
- Triplanar Rotary Resistance
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- High Point University
Lumbar Adjacent Spinal Stenosis, Chronic Low Back and Leg Pain
The Lumbar Adjacent Segment Stenosis Trial
The goal of this clinical trial is to learn if there are differences in the effectiveness of decompression surgery alone versus decompression combined with extended fusion in patients with a previous lumbar spinal fusion who now…
- Trial name
- LASS (NCT07670533)
- Testing
- Decompression alone, Decompression with extended fusion
- Where
- 3 sites in Norway
- Volunteers
- 192 people
- Sponsor
- Oslo University Hospital
Function, Pain
Comparative Study on Surgical Approaches for Elderly Femoral Neck Fractures
A prospective controlled study was conducted to include patients who received hip replacement surgery for femoral neck fractures at the National Regional Trauma Center in Fujian Province from February 2023 to August 2024.
- Trial name
- NCT06760949
- Testing
- Direct anterior approach hemiarthroplasty, Posterior lateral approach hemiarthroplasty
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Fujian Provincial Hospital
Hip Fractures, Peripheral Nerve Block
Pericapsular Nerve Block and Iliopsoas Fascial Plane Block in Hip Surgery
This prospective randomized interventional study aims to compare the effects of two peripheral nerve blocks, the periencapsular nerve block (PENG) and iliopsoas block (IPB), on analgesia and motor function after hip surgery.
- Trial name
- NCT06267716
- Testing
- PENG block, IPB
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital
Vascular Surgical Procedures
Pain Management of Amputation Wounds With AutoHypnosis
Amputation in vascular surgery mainly concerns the lower limb and is often linked to Obliterative Arterial Disease of the Lower Limbs.
- Trial name
- MODOUPAAH (NCT05779852)
- Testing
- self-hypnosis and dressing, dressing
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Rennes University Hospital
Piriformis Syndrome, Pes Planus
Investigation of the Relationship Between Pes Planus and Piriformis Syndrome: A Case-Control Study
The aim of this study is to investigate the relationship between Pes Planus and Piriformis Syndrome. The study will be conducted on individuals aged 18-65 years who are native Turkish speakers, have Turkish reading and writing…
- Trial name
- Piriformis (NCT07674433)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Restless Leg Syndrome (RLS)
Combined Effects of Near-Infrared Light and Vibration on Diabetic Patients With Restless Leg Syndrome
This Randomized Clinical Trial, titled "Combined Effects of Near-Infrared Light and Vibration on Pain, Sleep Quality and Symptom Severity in Diabetic Patients with Restless Leg Syndrome," aims to evaluate a non-pharmacological…
- Trial name
- NCT07308080
- Testing
- Near-Infrared Light Therapy, Vibration, Conventional Physical Therapy
- Volunteers
- 42 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Pain, Fracture of Neck of Femur
TRAUMEEL for Pain After Fracture of Neck of Femur
We hypothesize that Traumeel S is more effective than placebo in reducing 48-hour mean cumulative morphine consumption in patients scheduled for surgical correction of fracture of neck of hip.
- Trial name
- NCT00307905
- Testing
- Traumeel S
- Where
- Israel
- Volunteers
- 224 people
- Sponsor
- Shaare Zedek Medical Center
Diabetic Foot Ulcer
Effect of Virtual Reality on Pain, Anxiety and Vital Signs During Diabetic Foot Care
This study aims to determine the effects of a virtual reality (VR) intervention on pain level, state anxiety, and vital signs during foot care in individuals with diabetic foot ulcers.
- Trial name
- NCT07586423
- Testing
- VR, Standard Diabetic Foot Care
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Malatya Turgut Ozal University
ACL Tear, ACL
Comparing Adductor Canal Block and Adductor Canal Block-Local Infiltration Analgesia for Post-operative Pain Management
Anterior cruciate ligament (ACL) reconstruction is one of the most commonly performed surgeries amongst young orthopedic surgery patients.
- Conditions
- ACL Tear, ACL, ACL Injury
- Trial name
- NCT04721119
- Testing
- Local Infiltration Anesthetic, Local Infiltration Anesthetic + Adductor Canal Block
- Volunteers
- 100 people
- Sponsor
- Ottawa Hospital Research Institute
Knee Injuries
Comparison Of Isometric And Isokinetic Strength Training Effects On Physical Performance In Athletes With Knee Pain
Frequent sports events causing more injuries in athletes causing decline in their performance. Injuries around knee joint are common. Strength training of hamstring and quadriceps are effective tool in rehabilitation.
- Trial name
- NCT03641781
- Testing
- isometric strength training and isokinetic strength training
- Volunteers
- 50 people
- Sponsor
- Isra University
Myofascial Trigger Point, Gastrocnemius Muscle
Effects of Myofascial Induction Pressure Pain Threshold in Trigger Points of the Proximal Muscles of Gastrocnemius
In the present study we will test the effects of myofascial induction technique in the muscles close to the application in the gastrocnemius muscle.
- Conditions
- Myofascial Trigger Point, Gastrocnemius Muscle, Manual Therapy, Pain Threshold
- Trial name
- NCT06499493
- Testing
- Myofascial induction in gastrocnemius muscle
- Where
- Spain
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Mayuben Private Clinic
Leg Length Inequality
Study to Assess the Pain, Satisfaction, and Quality of Life of Patients With FITBONE® Lengthening Nail
This study is a prospective observational non-interventional multi-centre cohort study of patients, 12 years or older, initiating a lower limb lengthening procedure with FITBONE and who have a length discrepancy of 30mm or more…
- Trial name
- FitForFrance (NCT06156384)
- Testing
- FITBONE® Lengthening Nail
- Where
- 6 sites in France, Reunion
- Volunteers
- 45 people
- Sponsor
- Orthofix s.r.l.
Varicose Veins of Lower Limb, Chronic Venous Insufficiency, CVI
Efficacy and Safety of Endovenous Ablation for Relief of Knee Pain in Elderly Patients With Lower Extremity Varicose Veins: A Prospective Observational Study
Lower extremity varicose veins (LEVV) are common among elderly patients and can cause leg heaviness, pain, and swelling. In some older adults, venous congestion may contribute to knee or peri-knee pain, which is often…
- Conditions
- Varicose Veins of Lower Limb, Chronic Venous Insufficiency, CVI, Knee Pain, Knee Osteoarthritis
- Trial name
- EVA-Knee-Elder (NCT07239284)
- Testing
- Endovenous Ablation for Varicose Veins
- Volunteers
- 50 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine