Clinical trials: Lower Limb
Aging, Asymmetry
Fall Risk in Adults Over 65: The Relevance of Morphological and Functional Lower Limb Asymmetries.
Falls among older adults represent a major public health burden. Approximately 30% of individuals aged 65 and older experience at least one fall each year.
- Conditions
- Aging, Asymmetry, Fall Risk Factors, Fall Prevention
- Trial name
- ASY&FALL (NCT07742397)
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Lower Limb Apophysitis (Severs, Osgood Schlatter, Sinding-Larsen Johansson)
Management of Lower Limb Apophysitis: A Cross-sectional Study on Long-term Impact on Health Status
Lower limb apophysitis cause long-term pain, decrease in function, and can reduce or completely hinder participation in sports and physical activity, yet there is little knowledge on the long-term consequences for health.
- Trial name
- NCT04313621
- Where
- Denmark
- Volunteers
- 1,218 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Restless Legs Syndrome, Pregnancy Related
The Effect of Compression Stockings on the Complaints of Pregnant Women With Restless Leg Syndrome
The aim of this project is to determine the effect of compression stockings on the complaints, well-being and sleep quality of pregnant women with restless legs syndrome (RLS).
- Conditions
- Restless Legs Syndrome, Pregnancy Related, Sleep Disorder
- Trial name
- NCT05795868
- Testing
- Compression stocks, Knee socks
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Hearing Impaired Children
Effects of Pilates and Balance Proprioception Exercises on Hearing Impairment
Static balance is the ability to hold the body in a specific position and posture, while dynamic balance is the ability to maintain balance while moving.
- Trial name
- NCT06198049
- Testing
- Pilates Training, Balance Proprioception Exercises
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Pregnancy Related
Effects of Foot Exercises and Hydrotherapy on Pedal Edema & Lower Extremity Function
To determine the Effects of foot exercises with and without hydrotherapy on pedal Edema \& lower extremity function in antenatal women.
- Trial name
- NCT05777538
- Testing
- hydrotherapy, foot exercises
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Pes Planus
Effect of Different Exercise Approaches on Balance and Proprioception in Individuals With Pes Planus
Pes planus; It can be defined as the valgus of the hindfoot while loading the foot, the disappearance of the medial longitudinal arch in the midfoot, and the supination of the forefoot relative to the hindfoot.
- Trial name
- NCT05549063
- Testing
- Mobility and Stability Exercise, Stretching Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Lower Limb Lymphedema
Development of a Clinical Screening, Diagnostic and Evaluation Tool for Patients With Lower Limb Lymphedema: Aim 1
Of all of the different measurement methods that are currently available for use in clinical practice for assessing the same lymphedema characteristic (for example water displacement versus perimetry, both assessing swelling) or…
- Trial name
- EvaLymph-Leg1 (NCT05269264)
- Testing
- Assessor A (first measurement): measurement methods and questionnaires for the assessment of LLL, Assessor B: measurement methods and questionnaires for the assessment of LLL, Assessor A (second measurement: measurement methods and questionnaires for the assessment of LLL
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction Rehabilitation
Eccentric Phase Biomechanics of the Countermovement Jump After Anterior Cruciate Ligament Reconstruction
Purpose: This study aims to better understand how force is produced during a vertical jump in individuals approximately six months after anterior cruciate ligament reconstruction compared with healthy individuals.
- Trial name
- DECAL (NCT07448064)
- Testing
- Countermovement Jump Force Platform Assessment, Isokinetic Test
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Haute Ecole ARC Sante
Wound Heal, Diabetic Foot Ulcer
Effect of Topical Ozone on The Healing Diabetic Foot Ulcer
Despite conflicting and contradictory evidence regarding its efficacy, some wound care centres have advocated and adopted ozone for treating DFU. However, there are gaps in the application of topical ozone therapy.
- Conditions
- Wound Heal, Diabetic Foot Ulcer, Ozone
- Trial name
- NCT05977309
- Testing
- Topical ozone therapy
- Where
- Indonesia
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Asmat Burhan
Anterior Cruciate Ligament Injury
Effect of Resistance Training on Jump Landing Mechanics in Young Female Athletes
The purpose of this study is to determine if jump landing mechanics in young female athletes can be improved with a resistance training intervention.
- Trial name
- NCT02043275
- Testing
- Leg training, Arm training
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Healthy
How Eccentric Closed Chain Training Affects Knee Strength and Muscle Properties in Soccer Players
The goal of this study is to learn whether a 6-week lower-body training program using closed kinetic chain (CKC) exercises with slow, controlled movements (called "eccentric time under tension") can improve leg muscle strength…
- Trial name
- NCT06987344
- Testing
- Field-based closed kinetic chain exercise with progressively increased time under tension, Regular soccer training routines
- Where
- Chile
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Americas - Chili
Lower Extremity Performance, Ankle Dorsiflexion
Immediate Effects of Ankle Joint Mobilization on Jump Performance in Healthy University Students
The purpose of this randomized controlled study is to investigate the immediate effects of ankle joint mobilization on countermovement jump performance and ankle dorsiflexion range of motion in healthy university students.
- Conditions
- Lower Extremity Performance, Ankle Dorsiflexion, Healthy Volunteers
- Trial name
- NCT07711379
- Testing
- Mobilization with Movement (MWM)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Diabetic Foot Ulcer
Electrical Stimulation and Expression of VEGF and NO in Diabetic Foot Ulcer
This study aimed to investigate the effect of low intensity cathodal direct current on the release of plasma vascular endothelial growth factor (VEGF) and nitric oxide (NO) in diabetic foot ulceration.
- Trial name
- NCT02019082
- Testing
- Electrical Stimulation (BTL-5000 series, United Kingdom)
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- giti torkaman
Diabetic Complications, Foot Care
Evaluation of Materials for the Distribution of Pressure in the Treatment of Neuroischemic Ulcers
The hypothesis of this study is based on the premise that pressure-distributing materials with superior biomechanical and tissue response properties will be capable of improving the healing rate of neuropathic ulcers.
- Trial name
- NCT07620379
- Testing
- felt padding
- Where
- Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Diabetes Mellitus, Type 2, Intermittent Claudication
Exercise Training for Patients With Poor Leg Circulation
The purposes of this pilot project are to (a) determine changes in calf muscle blood flow and energy supply resulting from calf muscle exercise, and (b) to determine changes in these variables resulting from exercise training…
- Trial name
- NCT00118560
- Testing
- Physical exercise, Physical walking
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Healthy
A Study of the Effect of BIIB023 on Muscle Atrophy in Healthy Male Volunteers
The primary objective of this study is to determine whether muscle atrophy induced by immobilization of the lower limb can be attenuated by BIIB023 in healthy male volunteers.
- Trial name
- NCT01943513
- Testing
- BIIB023
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Biogen
Functional Balance, Mobility Limitation
Adolescent Elite Athletes: Trunk Mobility, Lower Extremity Flexibility, and Functional Balance Across Sports
This cross-sectional observational study compared trunk mobility, hamstring flexibility, and dynamic functional balance performance among elite male adolescent athletes aged 15-17 years from different sports branches, including…
- Conditions
- Functional Balance, Mobility Limitation, Lower Extremity Problem
- Trial name
- TEF-BALANCE (NCT07395947)
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Athletic Performance, Neuromuscular Adaptations
Squat Jump Performance and Chiropractic Ankle Manipulation
The goal of this clinical trial is to learn if chiropractic ankle manipulation can improve squat jump performance. It will also learn about the relationship among chiropractic ankle manipulation, ankle range of motion, and squat…
- Conditions
- Athletic Performance, Neuromuscular Adaptations, Lower Limb, Chiropractic Manipulation
- Trial name
- NCT07641621
- Testing
- Manual Therapy Procedure: Chiropractic Ankle Manipulation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northeast College of Health Sciences
Hemiparesis Proprioceptive Disorders Gait, Hemiplegic, Healthy Individual, Comparative Study
Lower Extremity Proprioception Sensory and Functionality in Hemiparetic
The loss of sensorial feedback causes gait impairment in hemiparesis. The studies show that proprioceptive impairment of knee is related to falling in these patients.
- Trial name
- NCT05062187
- Testing
- Proprioseption in hemiparetics
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Hip Fractures, Anesthesia, Local
Shamrock - Ultrasound/MR Image Fusion Guided Lumbar Plexus Block
The main objective is to complete a double-blinded randomized controlled crossover trial of lumbar plexus block with the Shamrock technique guided by ultrasound (US)/magnetic resonance imaging (MRI) image fusion vs.
- Conditions
- Hip Fractures, Anesthesia, Local, Pain, Postoperative
- Trial name
- NCT02718976
- Testing
- Lidocaine-epinephrine added gadoterate meglumine
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
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