Clinical trials: Lower Limb Trauma
ACL - Anterior Cruciate Ligament Rupture
SharkScrew ACL RCT
This prospective, randomized controlled trial will compare three tibial interference screw types used for graft fixation during primary anterior cruciate ligament (ACL) reconstruction: a polyetheretherketone (PEEK) screw, a…
- Trial name
- NCT07830953
- Testing
- ACL Reconstruction with a Biocomposite Screw, ACL Reconstruction using a PEEK Screw, ACL Reconstruction using an Allograft Screw
- Where
- Austria
- Volunteers
- 33 people
- Sponsor
- Austrian Workers Compensation Board Styria
Hip Fractures
Analgesic Effect of Fascia Iliaca Compartment Block in Geriatric Patients With Hip Fracture
As population in Hong Kong is aging, incidence of geriatrics hip fractures rises. Operative treatment for selective patients offers pain control, early mobilization and reduction in medical morbidities and mortalities.
- Trial name
- NCT04478552
- Testing
- Fascia iliaca compartment block
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- United Christian Hospital
Tibial Plateau Fractures
Local Anesthetic for Plateau Fractures
Subjects may receive an injection at the end of the surgery to fix their broken leg that may reduce their pain and hospital stay
- Trial name
- NCT06474949
- Testing
- Bupivacaine injection, Saline
- Volunteers
- 100 people
- Sponsor
- University of Washington
Postoperative Delirium, Hip Fractures
The Southeast and East Asian Post-Operative Delirium (SEAPOD) Study
The specific aim of the study will be to investigate the incidences and risk factors for postoperative delirium (POD) after hip fracture surgery in elderly patients aged ≥ 65 years in five different Southeast and East Asian…
- Trial name
- NCT04999891
- Testing
- Neurocognitive tests
- Where
- 13 sites in Japan, Malaysia and 3 more
- Volunteers
- 1,000 people
- Sponsor
- National University Hospital, Singapore
Anesthesia Morbidity, Anesthesia; Adverse Effect
Comparison of CLSB With Sedation Versus General Endotracheal Anesthesia on Postoperative Outcomes in Elderly Patients Undergoing Hip Fracture Surgery
Hip fracture is a global public health problem. The postoperative mortality and disability rate of hip fracture is high, and early surgery is still the most effective treatment method, but these patients are often associated with…
- Trial name
- NCT03318133
- Testing
- anesthesia
- Where
- China
- Volunteers
- 1,086 people
- Sponsor
- Shanghai 6th People's Hospital
Pelvic Fracture, Morel-Lavallee Lesion
A Retrospective Cohort Study of 15 Cases of Pelvic Fractures Complicated by Morel-Lavallee Lesion
Some related factors of pelvic fracture and Morel-Lavallee injury (MLL) are preliminarily discussed, which provides some preliminary references for early clinical detection and research of such injuries.
- Trial name
- NCT06388915
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Weikang Chen
Diabetic Foot Ulcer
RESPOND Restoring Equilibrium and Wound Stimulation to Promote Healing Of Non-healing DFUs
To evaluate the safety and effectiveness of MIST Therapy in conjunction with Standard of Care (SOC) compared to Standard of Care alone in the treatment of diabetic foot ulcers (DFU).
- Trial name
- NCT01608776
- Testing
- MIST Therapy, SOC - Standard of Care
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Celleration, Inc.
Diabetic Foot Ulcer
Exercise Enhances Wound Healing in Patients With Diabetic Foot Ulcers
The overarching purpose of this study is to investigate the impact that exercise, as delivered through a medically supervised, outpatient cardiac rehabilitation program, has on the wound healing process in Type 2 diabetics having…
- Trial name
- NCT04791449
- Testing
- Structured exercise program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of New Mexico
Hip Fracture, Depression
Enhanced Medical Rehabilitation for Disablement
This study will develop and test a new program of enhanced medical rehabilitation for elderly people who have had an acute disabling medical event and are admitted to a skilled nursing facility for post-acute rehabilitation.
- Trial name
- NCT00951691
- Testing
- Enhanced acute medical rehabilitation, Treatment as usual
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Washington University School of Medicine
Ankle Sprains
Comparison Between Two Mobilization Techniques of Ankle on Balance in Patients With Chronic Ankle Instability
The ankle joint is often affected by injuries, especially lateral sprains, often leading to chronic instability. Joint mobilization techniques seem to influence the sense of joint positioning.
- Trial name
- NCT03079804
- Testing
- Experimental MWM, Experimental Thrust
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Universidade Federal do Ceara
Anterior Cruciate Ligament Injuries, Atrophy, Muscular
Bilateral Versus Unilateral Strength Training After ACLR
After rehabilitation completion, there remains large deficiencies between the operative (OP) and non-operative (NOP) limbs in lower-limb outcomes (e.g., size, strength, and function) and these deficits can persist for years.
- Conditions
- Anterior Cruciate Ligament Injuries, Atrophy, Muscular, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- BUST (NCT06032247)
- Testing
- Resistance exercise program- UL, Resistance exercise program- BL
- Where
- United States
- Sponsor
- University of Kansas
Anterior Cruciate Ligament (ACL) Injury, Athletic Injuries
Correlation Between Psychological Readiness, Knee Function, and Isokinetic Performance After Anterior Cruciate Ligament Reconstruction (ACLR) Using Peroneus Longus Tendon Graft (PL-ACL-2025)
This clinical trial aims to investigate the correlation between psychological readiness, knee function, and isokinetic performance after anterior cruciate ligament reconstruction (ACLR) using the Peroneus Longus tendon graft…
- Conditions
- Anterior Cruciate Ligament (ACL) Injury, Athletic Injuries, Knee Injuries
- Trial name
- PL-ACLR (NCT07201597)
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Ankle Injuries, Treatment Outcome
Assessment of the Quality of Life of Patients Visiting the Emergency Department of the Saint-Brieuc Hospital Following an Ankle Sprain
Lateral ankle sprains account for nearly 6,500 emergency department visits per day in France. They are clinically classified into three grades, which can be assessed approximately 3-5 days after an acute sprain.
- Trial name
- EntoQuaVie (NCT07054892)
- Testing
- FAAM - Activities of Daily Living (ADL) Subscale
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier de Saint-Brieuc
Patellar Dislocation, Anatomic Abnormality
The Influence of Anatomic Deformities on the Clinical Efficacy in the Patients With Patellar Dislocation
All the data of patients with patellar dislocation will be collected to evaluate the anatomic deformities. The data includes X-ray, CT, MRI examinations, medical records, and physical examination information.
- Conditions
- Patellar Dislocation, Anatomic Abnormality, Trochlear Dysplasia, Femoral Anteversion
- Trial name
- NCT05243134
- Testing
- Collect the clinical data
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Peking University Third Hospital
Femoral Neck Fracture
Allogeneic Mesenchymal Stromal Cells in Elderly Patients With Hip Fracture
Prospective, unicenter, randomized, open-label, single-dose, two-arms blinded assessor pilot study. Thirty-two (32) elderly patients with hip fracture will be randomized to one of the two treatment-arms (Xcel-MT-osteo-beta or…
- Trial name
- NCT02630836
- Testing
- XCEL-MT-OSTEO-BETA, Surgical treatment
- Sponsor
- Banc de Sang i Teixits
Patellofemoral Joint Dislocation, Bicep Tendon Rupture
BFR After Biceps Tendon Repair and MPFLR
The purpose of this study is to examine the effect of utilizing blood flow restriction (BFR) therapy after distal biceps tendon repair or medial patellofemoral ligament reconstruction (MPFLR) following a tear.
- Trial name
- NCT05375071
- Testing
- Blood Flow Restriction (BFR) Therapy, Physical Therapy
- Where
- United States
- Sponsor
- Mayo Clinic
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction Rehabilitation
Eccentric Phase Biomechanics of the Countermovement Jump After Anterior Cruciate Ligament Reconstruction
Purpose: This study aims to better understand how force is produced during a vertical jump in individuals approximately six months after anterior cruciate ligament reconstruction compared with healthy individuals.
- Trial name
- DECAL (NCT07448064)
- Testing
- Countermovement Jump Force Platform Assessment, Isokinetic Test
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Haute Ecole ARC Sante
Wound Heal, Diabetic Foot Ulcer
Effect of Topical Ozone on The Healing Diabetic Foot Ulcer
Despite conflicting and contradictory evidence regarding its efficacy, some wound care centres have advocated and adopted ozone for treating DFU. However, there are gaps in the application of topical ozone therapy.
- Conditions
- Wound Heal, Diabetic Foot Ulcer, Ozone
- Trial name
- NCT05977309
- Testing
- Topical ozone therapy
- Where
- Indonesia
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Asmat Burhan
Hip Fractures
Improving Quality of Care for Hip-Fracture Patients: Studies on Fast-track Surgery
The aims of the studies are to examine the impact of delayed time to surgery for hip-fracture patients with regard to in-hospital complication rate and one-year mortality and to evaluate two different fast-track systems for…
- Trial name
- Q-HIP (NCT01487772)
- Where
- Sweden
- Volunteers
- 1,307 people
- Sponsor
- Danderyd Hospital
Anterior Cruciate Ligament Injury
Effect of Resistance Training on Jump Landing Mechanics in Young Female Athletes
The purpose of this study is to determine if jump landing mechanics in young female athletes can be improved with a resistance training intervention.
- Trial name
- NCT02043275
- Testing
- Leg training, Arm training
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
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