Clinical trials: Lung Surgery
Lung Diseases
Continuous Erector Spinae Plane Block or Thoracic Epidural Analgesia Following Video Assisted Thoracic Surgery
Video assisted thoracic surgery (VATS) has recently been evaluated as the standard surgical procedure for lung surgery. Although VATS is less painful than thoracotomy, patients may feel severe pain during the first hours at…
- Trial name
- NCT03960736
- Testing
- ESP block (Group A), TEA group (Group B)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Medipol University
Intercostal Nerve Block, Pulmonary Ventilation
EIT Evaluation of Pulmonary Ventilation With Different Ropivacaine Concentrations in Intercostal Nerve Blockade
This study aims to find out how different strengths of the anesthetic drug ropivacaine affect lung breathing function when used in intercostal nerve block (a type of local anesthesia) for breast quadrantectomy surgery.
- Conditions
- Intercostal Nerve Block, Pulmonary Ventilation, Anesthesia, Local, Breast Neoplasms
- Trial name
- EIT (NCT07079436)
- Testing
- 0.25% ropivacaine, 0.375% Ropivacaine, 0.5% Ropivacaine
- Where
- China
- Volunteers
- 67 people
- Sponsor
- Fudan University
Colorectal Neoplasms Malignant
Effects of COVID-19 Pandemic on the Outcomes of Colorectal Cancer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been identified as the cause of the Coronavirus disease 19 (COVID-19), which was initially reported in December 2019 in China and has since rapidly spread…
- Trial name
- COVID-CRC (NCT04712292)
- Testing
- Surgical procedure for confirmed or suspected colorectal cancer
- Where
- 45 sites in Italy
- Volunteers
- 15,000 people
- Sponsor
- University of Bologna
Carcinoma, Non Small Cell Lung
Healthy Directions After Lung Surgery Pilot
The objective of this proposal is to test the feasibility and acceptability of a lifestyle risk reduction intervention for patients with lung cancer receiving surgical treatment.
- Trial name
- NCT02135211
- Testing
- Lifestyle counseling
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- Dana-Farber Cancer Institute
Non-small Cell Lung Cancer, Oligometastatic Disease
Liquid Biopsy in Advanced Oligometastatic NSCLC Receiving Surgery
A prospective, observational study that assesses the clinical feasibility of ctDNA-based liquid biopsy in patients with oligometastatic NSCLC receiving surgery.
- Trial name
- NCT05648370
- Testing
- ctDNA testing and whole exome sequencing
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Guangdong Provincial People's Hospital
Lung Cancer, Surgery
Pulmonary Rehabilitation After Minimal Invasive Surgery in Lung Cancer
Morbidity in the post-operative phase of pulmonary surgery is characterised by impairment due to pain, dyspnoea and loss of exercise tolerance.
- Trial name
- PROMISE (NCT05136300)
- Testing
- Pulmonary rehabilitation
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Isala
Right-sided Double-lumen Tube Positioning, Lung Isolation During Thoracoscopic Surgery
Video-guided Versus Conventional Right-sided Double-lumen Tube Placement for Thoracoscopic Surgery
Right-sided double-lumen tubes are used for lung isolation during thoracoscopic surgery but can be difficult to position because of right bronchial anatomy.
- Conditions
- Right-sided Double-lumen Tube Positioning, Lung Isolation During Thoracoscopic Surgery, One-lung Ventilation, Lung Cancer
- Trial name
- NCT07849400
- Testing
- Continuous video-guided right-sided double-lumen tube, Conventional right-sided double-lumen tube
- Where
- 3 sites in China
- Volunteers
- 566 people
- Sponsor
- Diansan Su
Pneumoperitoneum
Influence of Posture and Gas Insufflation on Perioperative Lung Function
Perioperative airway resistance and lung function are evaluated perioperatively in patients, who undergo surgical procedures in different postures and with or without gas insufflation into the peritoneal cavity.
- Trial name
- NCT00948571
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Kliniken Essen-Mitte
Asthma, Obesity
Contributing Factors in the Pathobiology of Airway Remodeling in Obesity
There are two aims for this study. The purpose of this study is to determine the effects of body weight and hormones on airway fibrosis (scarring) and lung function in obese \& lean asthma subjects compared to obese \& lean…
- Conditions
- Asthma, Obesity, Obesity, Morbid, Bariatric Surgery Candidate
- Trial name
- NCT03115632
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Duke University
Heart Defects, Congenital, Hypertension, Pulmonary
Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery
This clinical trial will determine the safety and effectiveness of intravenous L-citrulline in children undergoing cardiopulmonary bypass during heart surgery.
- Trial name
- NCT00335244
- Testing
- L-citrulline
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Asklepion Pharmaceuticals, LLC
Surgery, Lung Adenocarcinoma
Shared Decision Making in Patients With Lung Cancer
The objective of this study is to develop a Decision Aid for Lung Cancer Molecular Testing (DA_LCMT) and to facilitate shared-decision making in patients who were diagnosed with lung adenocarcinoma by intraoperative frozen…
- Trial name
- NCT05191485
- Testing
- Qualitative interviews
- Where
- China
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Sichuan Cancer Hospital and Research Institute
Lung Neoplasms, Pneumothorax
HFNO Improves Blood Oxygen Saturation During Asphyxia During Pulmonary Surgery With Double-lumen Endotracheal Intubation
With the continuous strengthening of the concept of rapid rehabilitation, great progress has been made in minimally invasive thoracic surgery, and thoracoscopic surgery has developed rapidly.
- Trial name
- NCT05666908
- Testing
- HFNO
- Volunteers
- 112 people
- Sponsor
- Shenzhen Second People's Hospital
Double Lumen Endotracheal Tube, Single Lung Ventilation
VivaSight Double Lumen Tube for Single Lung Ventilation
This prospective, randomized, comparative study is intended to enroll a total of 50 patients undergoing thoracic surgery that necessitates single lung ventilation.
- Trial name
- NCT03690284
- Testing
- Conventional Double Lumen Tube, VivaSight Double Lumen Tube
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Collapsed Lung, Hemodynamic Stability
Role of Inhaled Nitric Oxide in Vascular Mechanics and Right Ventricular Function
The aim of this study is to evaluate the role of nitric oxide on pulmonary vasculature and right ventricular function in postoperative cardiac surgery patients.
- Trial name
- NCT06097026
- Testing
- Alveolar recruitment maneuver, Nitric Oxide
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Fernando Suarez Sipmann
Postoperative Pain, Postoperative Complications
Protocol for Accelerated Recovery in Patients Undergoing Thoracic Surgical Procedures (PROSM). Study Randomized Comparative Between the Adoption of the Proposed Guidelines and the Traditional Method Currently Used in the Institution
Introduction: Aiming at reducing costs and optimizing the use of these financial resources, several postoperative recovery protocols have emerged that aim to reduce the length of hospital stay by accelerating surgical…
- Conditions
- Postoperative Pain, Postoperative Complications, Postoperative Nausea, Lung Cancer
- Trial name
- PROSM (NCT03271749)
- Testing
- PROSM guidelines for preoperative, anesthesia and postoperative care for lung resections
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Igor Renato Louro Bruno de Abreu
Lung Cancer
S0002 - A Program to Quit Smoking With or Without Bupropion in Treating Patients With Stage I or II Non-Small Cell Lung Cancer Who Have Undergone Surgery
RATIONALE: A program that includes bupropion may be more effective in helping early-stage lung cancer patients to quit smoking. It is not yet known if a program to quit smoking is more effective with or without bupropion.
- Trial name
- NCT00032084
- Testing
- smoking cessation intervention, bupropion hydrochloride, nicotine
- Where
- 176 sites in United States, Puerto Rico
- Volunteers
- 10 people
- Sponsor
- SWOG Cancer Research Network
Pulmonary Nodule, Pneumothorax
Safety And Recovery Of Tubeless Strategy In Uniportal VATS Wedge Resection
Brief Summary The goal of this clinical trial is to evaluate the safety and recovery outcomes of different tubeless strategies in adult patients undergoing uniportal video-assisted thoracoscopic (VATS) wedge resection who are…
- Conditions
- Pulmonary Nodule, Pneumothorax, Postoperative Complications
- Trial name
- NCT07395349
- Testing
- Conventional Chest Tube Drainage, Single Intraoperative Aspiration Tubeless, Double Intraoperative Aspiration Tubeless
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Non-Small Cell Lung Cancer
To Explore the Safety and Efficacy of Hypervision Proton Surgery for Early-stage Non-small Cell Lung Cancer
This study was a single-center, single-arm clinical study to evaluate the safety and efficacy of hypervision proton surgery with single large fractionated doses (34GyE and 39GyE) in the treatment of early peripheral NSCLC.
- Trial name
- HyPROS-LC (NCT07195084)
- Testing
- Hypervision proton surgery
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Anhui Provincial Cancer Hospital
Cardiac Surgery Requiring Cardiopulmonary Bypass
Oxygen Consumption, Hypoperfusion and Organ Injury After Cardio-pulmonary Bypass
The goal of this observational study is to understand how oxygen consumption after heart surgery relates to blood flow problems and organ injury.
- Trial name
- VO2-EPOC (NCT06930443)
- Testing
- Oxygen consumption measurement
- Where
- Sweden
- Volunteers
- 65 people
- Sponsor
- Uppsala University Hospital
Venous Thromboembolism, Deep Venous Thrombosis
Twice Daily Enoxaparin Prophylaxis in Reconstructive Surgery Patients
Blood clots that form in the extremities (deep venous thrombosis) and lungs (pulmonary embolus) are feared complications of reconstructive surgery.
- Conditions
- Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolus
- Trial name
- NCT02687204
- Testing
- Twice daily enoxaparin prophylaxis, Real time dose adjustment
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Utah
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