Clinical trials: Lung Volume
Atelectasis, Atelectases, Postoperative Pulmonary
Evaluation of Effect of Different Ventilator Mods on Atelectasis in Patients Undergoing Laparoscopic Surgery
In this study researchers aim to evaluate effect of different ventilation modalities on the developments of atelectasis by using ultrasound.
- Trial name
- PCV-VG (NCT03614845)
- Testing
- VCV, PCV-VG, lung ultrasonography
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Derince Training and Research Hospital
Asthma
Inspiratory Flow Using the Osmohaler
The OsmohalerTM is a registered device in Australia. It is used to deliver a dry powder a commercial preparation of mannitol registered as AridolTM to test if a person has irritable airways such as active asthma.
- Trial name
- NCT00531414
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Syntara
Pain, Hypoxia
Effects of Walking Apnea at Low Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function
The aim of this randomized controlled study is to explore the hypoalgesic response of a 6 minutes of intermittent walking apneas training session at low lung volume in healthy subjects; also, as secondary objectives, to analyze…
- Conditions
- Pain, Hypoxia, Hypercapnia, Apnea
- Trial name
- NCT06158295
- Testing
- Voluntary apnoea
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
Pulmonary Aspiration of Gastric Contents
Prophylaxis for Aspiration of Gastric Contents.
Effect of orally administered two equal and consecutive doses of proton pump inhibitors, omeprazole, lansoprazole, esomeprazole , rabeprazole and pantoprazole and Histamine 2 receptor antagonists cimetidine…
- Trial name
- NCT02703896
- Testing
- Drug either PPIS or H2RA and prokinetics, orogastric intubation
- Volunteers
- 1,920 people, healthy volunteers welcome
- Sponsor
- King Saud University
Mechanical Ventilation
DIAPHRAGM STRENGTH AND LUNG VOLUMES
Diaphragm dysfunction (loss of diaphragm strength) is common in the intensive care unit (ICU) patients using ventilators. The diaphragm is the main muscle of respiration and its dysfunction can prolong mechanical ventilation and…
- Trial name
- DIAVOLA (NCT07206459)
- Testing
- Healthy Patients, Critically Care Patients
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Diaphragmatic Function, Lung Function
Pulmonary Function Changes and Diaphragmatic Paralysis Following Ultrasound Guided Supraclavicular Brachial Plexus Blockade: The Effects of Decreased Local Anesthetic Volume
This clinical trial is being conducted to study lung function and movement of the major muscle involved in breathing (the diaphragm) after a brachial plexus nerve block (nerve "freezing").
- Trial name
- NCT01048021
- Testing
- Supraclavicular Block
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Sickle Cell Disease
Evaluation of the Lung Capillary Blood Volume in Children With Sickle Cell Disease
Sickle cell disease (SCD) is the most common inherited disease of the world affecting African and Caribbean populations. SCD is caused by the homozygous inheritance of the gene for sickle hemoglobin (HbS).
- Trial name
- VOLCADREP (NCT00560261)
- Testing
- NO-CO inhalation and expiration
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Septic Acute Kidney Injury
The Assessment of Volume Status by BIA and Lung Ultrasound in Septic AKI Patients Undergoing CRRT
Acute kidney injury(AKI) is one of the most common complications that occur up to 35% of critically ill patients. Septic AKI accounts for one third of them.
- Trial name
- NCT02384525
- Testing
- Fluid management by the value of over hydration in Bioelectrical impedance, Fluid management by clinical-based ultrafiltration
- Where
- South Korea
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Fasting, Surgery
Gastric Volume After Water or Jelly Ingestion
The aim of this study is to determine whether the fasting duration required for patients after consuming oral jelly is comparable to that after consuming water, prior to elective surgery.
- Conditions
- Fasting, Surgery, Ultrasound Therapy; Complications, Aspiration Pneumonia Due to Regurgitated Food
- Trial name
- NCT05737641
- Testing
- water ingestion, jelly ingestion
- Where
- Portugal
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar de Entre o Douro e Vouga
Postoperative Pulmonary Complications, Thoracic Surgery
Intermittent Positive Pressure Breathing Versus Incentive Spirometry After Thoracic Surgery
This randomized controlled pilot study will compare intermittent positive pressure breathing (IPPB) with incentive spirometry (IS) in adult patients undergoing thoracic surgery.
- Trial name
- NCT07867548
- Testing
- Intermittent Positive Pressure Breathing, Incentive Spirometry
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fu Jen Catholic University Hospital
Pulmonary Disease, Chronic Obstructive
Evaluation of COPD (Chronic Obstructive Pulmonary Disease) to Longitudinally Identify Predictive Surrogate Endpoints
This is a 3 year longitudinal study to identify novel endpoints and compare these with standard measures such as forced expiratory volume in 1 second (FEV1) for their ability to measure and predict COPD (Chronic Obstructive…
- Trial name
- ECLIPSE (NCT00292552)
- Testing
- Novel endpoint determination
- Where
- 44 sites in United States, Bulgaria and 10 more
- Volunteers
- 2,747 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Volume Overload
Perioperative Fluid Therapy in Pediatric Patients Undergoing Penile Hypospadias Repair
Optimization of perioperative fluid management is important for preventing adverse events, such as hypovolemia, cardiogenic shock, volume overload, and pulmonary edema, in both adult and pediatric patients.
- Trial name
- NCT04444089
- Testing
- lung ultrasound
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Postmenopausal Women
Ventilatory Constraint, Breathing Pattern and Ventilatory Responses in Obese Postmenopausal Women
The purpose of this study was to examine the dynamic lung volumes in obese post-menopausal women (without hormone replacement therapy) during exercise and their correlations with dyspnea.
- Trial name
- NCT01034098
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
COPD (Chronic Obstructive Pulmonary Disease), Healthy Subjects
Pulmonary and Total Blood Volume in COPD
Background Patients with chronic obstructive lung disease (COPD) suffer from a progressive loss of lung function that leads to poor quality of life, and often invalidity and early death.
- Trial name
- COPD-TBV (NCT07428785)
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Septic Shock, Fluid Reponsiveness
This Study Compares Two Noninvasive Dynamic Tools: Lung Ultrasound and Transthoracic Echocardiography Using LVOT VTI. It Aims to Measure the Sensitivity and Specificity of LUS in Guiding Fluid Resuscitation and Early Detection of Fluid Responsiveness and to Prevent Volume Overload
Reliability of the LVOT-VTI versus lung ultrasonography for early detection of fluid intolerance during fluid resuscitation of septic patients.
- Trial name
- lvotvti (NCT07797751)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dyspnea During Pregnancy, Physiological Changes in Pregnancy
Breathing Exercises Versus Incentive Spirometry in Third-Trimester Pregnancy
Shortness of breath (dyspnea) is commonly experienced during the third trimester of pregnancy due to physiological changes affecting the respiratory system.
- Conditions
- Dyspnea During Pregnancy, Physiological Changes in Pregnancy, Reduced Functional Endurance
- Trial name
- NCT07365163
- Testing
- Deep Breathing Exercises, Volume-Oriented Incentive Spirometry
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Older Women
Moderate-Intensity Treadmill Walking With Blood Flow Restriction Improves Pulmonary Volumes in Older Adults
This quasi-experimental pilot study evaluated the effect of 12 months of moderate-intensity treadmill walking with blood flow restriction (BFR) on pulmonary function in 14 trained older women.
- Trial name
- NCT07694349
- Testing
- Blood Flow Restriction, Aerobic training
- Where
- Chile
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidad Santo Tomas, Chile
Chronic Obstructive Pulmonary Disease
The Differences of Muscle Activity Between Patients With COPD and Healthy Adults
The purpose of this study attempts to investigate the differences and relationships of respiratory parameters, muscle activity, and dyspnea during ADL between patients with COPD and age-matched healthy participants.
- Trial name
- NCT04146948
- Testing
- no intervention
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Anesthesia, Perioperative/Postoperative Complications
Use of Heart-lung Interaction to Predict Haemodynamic Tolerance to the Open Lung Approach With Individualised PEEP
This is an observational, prospective, single-centre study that will focus on patients undergoing major non-cardiac surgery requiring invasive mechanical ventilation and invasive blood pressure monitoring Hypotheses: A positive…
- Conditions
- Anesthesia, Perioperative/Postoperative Complications, Hypovolemia, Haemodynamic Instability
- Trial name
- HiPEEP (NCT06123039)
- Testing
- Tidal Volume Challenge, Recruitment maneuver obtaining individualised PEEP
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Fe
Lung Cancer
Community Support Program for Lung Cancer Screening Volume II
This is a West Philadelphia based community project to improve adherence to lung cancer screening. The overall objective of this project is to demonstrate the impact of a community support program (CSP) on improve adherence to…
- Trial name
- LCS II (NCT06628167)
- Testing
- Transportation, Scheduling
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine