Clinical trials: Luteal Support
Infertility
Comapring Luteal Phase Support in IVF Patients Who Are at High Risk for Developing OHSS
The purpose of this study is to compare two luteal support protocols in In vitro fertilization patients (IVF) and are at risk of developing ovarian hyperstimulation syndrome (OHSS).
- Trial name
- NCT02827656
- Testing
- Decapeptyl, hCG luteal support
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Effect of Adding GnRHa as Luteal Phase Support in Antagonist ART Cycles
Role of Triptorelin 0.1 mg as a Luteal Phase Support in Assisted Reproductive Technique After Embryo Transfer : a Randomized Controlled Trial
There is still controversy over the best LPS agent and protocol and its dose and duration as well as the time of initiation and cessation.
- Trial name
- NCT04087408
- Testing
- Effect of adding gonadotropins releasing hormone agonist to progesterone for luteal phase support in assisted reproductive technique )antagonist cycles(: a randomized controlled trial
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Moustafa Mohammed Abouelea
IVF
Lactobacillus for Luteal Phase Support
The aim of this study was to evaluate the effect of vaginal lactobacilli, a regulator of normal vaginal flora, on embryo implantation success during IVF / ICSI cycle follow-up.
- Trial name
- NCT04044599
- Testing
- Gynoflor
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Uludag University
Pregnancy
Endometrial Injury Versus Luteal Phase Support in Intrauterine Insemination Cycles
The investigators will try to assess the effect of endometrial injury preceding the intrauterine insemination cycle on the pregnancy rates compared to cycles with luteal phase support and the control group.
- Trial name
- NCT02492451
- Testing
- Endometrial Injury, progesterone (Crinone® %8 vaginal progesterone gel)
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
IVF
Luteal Phase Estradiol Support for In Vitro Fertilization/Intracytoplasmic Sperm Injection Cycles
Optimizing in vitro fertilization (IVF) success is more important than ever, in light of new public funding of IVF in Ontario, Canada.
- Trial name
- NCT02677259
- Testing
- 17-beta estradiol, Micronized progesterone
- Volunteers
- 506 people, healthy volunteers welcome
- Sponsor
- One Fertility
Infertility, Female, Infertility
Oral Dydrogesterone (OD) Versus Micronized Vaginal Progesterone (MVP) for Luteal Phase Support (LPS) in IVF/ICSI
Female inability to conceive a child. The purpose of this prospective randomized, double-blinded, double dummy, two-arm cross-over study is to investigate the difference on histological, transcriptional and immunological level in…
- Conditions
- Infertility, Female, Infertility, Genital Diseases, Male, Genital Diseases, Female
- Trial name
- NCT03677336
- Testing
- Dydrogesterone Oral Tablet, Micronized progesterone
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CRG UZ Brussel
Obesity, Maternal
The Application of HCG in Luteal Support for Frozen Embryo Transfer in Ovulation Cycle of Obese Women
This study aims to explore whether the application of low-dose HCG in luteal support can improve the pregnancy outcomes of natural cycle frozen embryo transfer in obese patients
- Trial name
- NCT07633002
- Testing
- Human Chorionic Gonadotropin
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Shandong University
IVF, Luteal Phase Defect
Luteal Phase Support In IVF Women Using GnRH Agonist
Lately, the role of GnRH agonist as luteal phase support has been recommended by various studies though the mechanism is still debatable.
- Trial name
- NCT04174378
- Testing
- Decapeptyl 0.2mg
- Where
- Malaysia
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Pregnancy Rate
The Effect of GnRH Administration During Luteal Support in Frozen-thawed Transfer Cycles
GnRH administration during the luteal phase was found to significantly increase pregnancy rates in women undergoing fresh-cycle IVF cycles.
- Trial name
- NCT01933009
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Infertility, Female, Infertility, Male
Oral Dydrogesterone vs. Micronized Vaginal Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer Cycles
The aim of this randomized controlled trial is to compare the efficacy of oral dydrogesterone vs. micronized vaginal progesterone for luteal phase support in frozen-thawed embryo transfer cycles.
- Conditions
- Infertility, Female, Infertility, Male, Embryo Transfer, Fertilization in Vitro
- Trial name
- NCT04124913
- Testing
- Dydrogesterone 10 MG Oral Tablet, Progesterone Vaginal Gel [Crinone]
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Memorial Sisli Hospital, Istanbul
Progesterone
Comparison of the Effect of Subcutaneous Progesterone and Vaginal Progesterone for Luteal Phase Support
The invesigators aimed to seperate the patients,which is going to be applied IUI, to two different groups as prospective randomized controlled ;assess the efficacy of the two different way pressurised progesterone by appling…
- Trial name
- NCT05276531
- Testing
- subcutaneous progesterone, vaginal progesterone
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Infertility
The Effect of GnRH Agonist Administered in the Luteal Phase on ART Cycle Outcomes
This prospective clinical trial evaluates the effect of a two dose GnRH agonist administered in the luteal phase on the outcome of ART cycles stimulated with the long GnRH agonist and GnRH antagonist protocol.
- Trial name
- NCT02114645
- Testing
- Leuprolide acetate, vaginal progesterone, 4 mg oral estradiol valerate
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Implantation; Placenta, Pregnancy Loss
Luteal Support in Frozen-Thawed Embryo Transfer Cycles
This study evaluates the clinical efficacy of 3 different luteal phase support in patients undergoing frozen-thawed embryo transfer cycles. Endometrium preparation will be hormone replacement in all cycles.
- Conditions
- Implantation; Placenta, Pregnancy Loss, Frozen Embryo, Luteal Support
- Trial name
- NCT03948022
- Testing
- Dydrogesterone 10Mg Tablet (duphaston), Progesterone 50Mg/mL Oil, Crinone 8% Vaginal Gel
- Where
- Turkey (Türkiye)
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Centrum Clinic IVF Center
Pregnancy Related, Infertility, Female
Comparison of Live Birth Rate in Natural Cycle Single Euploid FET Versus Without Luteal Phase Support
To evaluate whether single euploid embryo transfer in NC without routinely administered LPS is non-inferior to NC with routinely administered LPS.
- Trial name
- NCT05969795
- Testing
- Transvaginal ultrasound, Serial serum LH, E2, P4, Progesterone 100 Mg Vaginal Insert
- Where
- 3 sites in United Arab Emirates
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Subfertility
Does Hormonal Luteal Support After Intra-uterine Insemination (IUI) Increase the Pregnancy Rate?
A randomized study to investigate if hormonal luteal support after intra-uterine insemination (IUI) in ovulation induction cycles with human menopausal gonadotropin increases the pregnancy rate
- Trial name
- NCT00700492
- Testing
- progesterone
- Where
- Belgium
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg