Clinical trials: Lymph Node
Lymphadenopathy Retroperitoneal, Stage II Testicular Seminoma
R-RPLND as First-line Treatment for Clinical Stage IIA/B Testicular Seminoma
This study will investigate the safety and efficacy of using robotic retroperitoneal lymph node dissection (R-RPLND), a minimally invasive surgical approach, as the first-line of treatment for stage IIA/B (or equivalent) seminoma…
- Trial name
- NCT05345158
- Testing
- Robotic Retroperitoneal Lymph Node Dissection (RPLND)
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University Health Network, Toronto
Prostate Cancer
Neoadjuvant Hormones + Docetaxel in Node-Positive Prostate Cancer
The goal of this clinical research study is to find out if a therapy using docetaxel chemotherapy with hormonal therapy taken before your scheduled surgery is beneficial to treatment of prostate cancer.
- Trial name
- NCT01076335
- Testing
- Neoadjuvant Hormonal Therapy, Docetaxel
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- M.D. Anderson Cancer Center
Head and Neck Cancer, Multiparametric MRI
Use of Multiparametric MRI in the Management of Head and Neck Cancer: a Retrospective Analysis
The investigators aim to identify specific MRI parameters that could improve diagnostic accuracy of metastatic cervical lymph nodes in patients with a squamous cell carcinoma in the head and neck region.
- Conditions
- Head and Neck Cancer, Multiparametric MRI, Cervical Lymph Node
- Trial name
- NCT03991533
- Testing
- multiparametric MRI
- Volunteers
- 30 people
- Sponsor
- AZ Sint-Jan AV
Hypopharyngeal Carcinoma
Neck Dissection vs Radiotherapy for Cervical Metastases in Advanced Hypopharyngeal Cancer
At the time of diagnosis, approximately 60%-80% of patients with hypopharyngeal cancer are found with cervical lymph node metastasis. Cervical nodal metastasis is an important prognostic factor in hypopharyngeal cancer.
- Trial name
- NCT03367884
- Testing
- Neck dissection followed by radiotherapy(50Gy) according to risk factors, Definitive radiotherapy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Lymph Node Resection
Use of Tachosil® for Lymph Sealing During Surgery
The purpose of this study is to describe effectiveness and reliability of TachoSil® in lymph sealing after lymphadenectomy.
- Trial name
- SEAL (NCT01920958)
- Testing
- TachoSil®
- Where
- Germany
- Volunteers
- 233 people
- Sponsor
- Takeda
Prostate Cancer
ICG-based Fluorescence Imaging in Localization of Prostate Cancer and Metastatic Lymph Nodes
This study aims to evaluate the feasibility of indocyanine green (ICG)-based fluorescence imaging in the detection of prostate tumors and metastatic lymph nodes.
- Trial name
- NCT02840617
- Testing
- Indocyanine Green (ICG)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Disorder of Upper Gastrointestinal Tract, Pancreatic Nodule
Tissue Characterisation by Endoscopic GI-elastography
In this single centre study we study the use of endoscopic ultrasonography (EUS) combined with elastography in order to separate malignant tissue from benign tissue in and adjacent to the upper gastrointestinal tract.
- Conditions
- Disorder of Upper Gastrointestinal Tract, Pancreatic Nodule, Secondary and Unspecified Malignant Neoplasm of Retroperitoneal Lymph Nodes, Secondary Malignant Neoplasm of Lymph Node
- Trial name
- NCT01360411
- Where
- Norway
- Volunteers
- 137 people
- Sponsor
- Haukeland University Hospital
Thyroid Papillary Carcinoma, Contrast Enhanced Ultrasound
Preoperative Prediction of Lymph Node Metastasis in T1N0M0 Papillary Thyroid Carcinoma by Using Contrast-enhanced Ultrasound
Similarly, the burden of central lymph node metastasis affects the individualized management of patients with T1N0M0 papillary thyroid carcinoma (PTC): lymph node metastasis is a contraindication to thermal ablation; low-burden…
- Trial name
- NCT07357571
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Prostate Cancer Recurrent, Prostate Cancer
SBRT for Oligometastatic Lymph Node Recurrence in Prostate Cancer: a Single Institution Experience
Single-institution retrospective analysis for predictive factors of prostate cancer patients presenting with isolated or limited lymph node (LN) recurrence (1-3 lesions) on F-Ccholine PET-CT (CholPET) treated with SBRT between…
- Conditions
- Prostate Cancer Recurrent, Prostate Cancer, Lymph Node Metastases
- Trial name
- NCT03604211
- Testing
- Cyberknife Radiation Therapy
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- Kantonsspital Graubünden
Rectal Cancer
Open or Laparoscopic Mesolectal Excision in Low Rectum Cancer
To compare the open approach and the laparoscopic-assisted approach of dissection of lateral lymph nodes in low advanced rectal cancer patients with clinically suspected nodal metastases in terms of safety, technical feasibility…
- Trial name
- NCT04561830
- Testing
- laparoscopic-assited excision of mesorectum with pelvic lymph nodes excision
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Breast Cancer
Preoperative and Intraoperative Quantification of Axillary Tumoral Load
At present, patients diagnosed of a breast cancer with infiltration of the axillary lymph-nodes are submitted to axillary lymph-node dissection (ALND).
- Trial name
- NCT02197949
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Parc de Salut Mar
Breast Cancer
Photoacoustic Lymph Node Imaging
In this spectroscopic photoacoustic imaging study, the investigators will acquire images (only) to: 1. determine if spectroscopic photoacoustic imaging can acquire high fidelity images in a clinical setting, 2.
- Trial name
- NCT03931655
- Testing
- Spectroscopic photoacoustic imaging
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Geoff Luke
Prostate Cancer
Phase I Clinical Trial of Cryoimmunotherapy Against Prostate Cancer
20 patients with invasive castration resistant prostate cancer and radiologically verified metastases will be enrolled into the Phase I Clinical Trial. The trial is a dendritic cell based immunotherapy.
- Trial name
- CryoIT (NCT02423928)
- Testing
- Dendritic cell based cryoimmunotherapy, Cyclophosphamide, ipilimumab
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- Alden Cancer Therapy II
Prostate Cancer Recurrent
Salvage Lymph Node Dissection in Prostate Cancer Patients With Recurrence After Radical Prostatectomy
Despite continuous technical improvements in urologic surgery, up to 40% of prostate cancer patients will develop biochemical recurrence after radical prostatectomy (RP), potentially because of micro metastasis at the time of the…
- Trial name
- NCT02974075
- Testing
- Salvage lymph node dissection
- Where
- Austria
- Volunteers
- 65 people
- Sponsor
- Medical University of Vienna
Pancreas Cancer, Pancreatic Adenocarcinoma
Dissecting the Pattern of Nodal Spread in Post-neoadjuvant Pancreatoduodenectomy
There has been long-standing debate about nodal dissection in pancreatoduodenectomy (PD) for pancreatic ductal adenocarcinoma (PDAC), with most studies examining the value of nodal yields, number of metastatic nodes and spatial…
- Trial name
- NCT06135649
- Testing
- Systematic lymphadenectomy
- Where
- Italy
- Volunteers
- 850 people
- Sponsor
- Universita di Verona
Kawasaki Disease Refractory to Initial Therapy With Intravenous Immunoglobulin
Clinical Study of TA-650 in Patients With Refractory Kawasaki Disease
The purpose of this study is to evaluate the efficacy and safety of TA-650 in comparison with a control drug Polyethylene Glycol-treated Human Immunoglobulin (VGIH) in patients with Kawasaki disease refractory to initial therapy…
- Trial name
- NCT01596335
- Testing
- TA-650, Polyethylene Glycol-treated Human Immunoglobulin (VGIH)
- Where
- 8 sites in Japan
- Volunteers
- 31 people
- Sponsor
- Tanabe Pharma Corporation
Breast Cancer
Evaluation of NeoNavia® Biopsy System in Axillary Lymph Nodes
The aim of the study is to document performance characteristics of a biopsy device indicated for use in axillary lymph nodes, to provide basic insights into the complexity of axillary biopsy procedures and generate hypothesis for…
- Trial name
- PULSE (NCT03975855)
- Testing
- NeoNavia® Biopsy System
- Where
- 7 sites in Germany
- Volunteers
- 140 people
- Sponsor
- NeoDynamics AB
Colorectal Cancer
Clinical Application of Carbon Nanoparticles in Lymph Node Tracing and Surgery Guiding of Colorectal Cancer
This trial aims to clarify the relationship between carbon nanoparticles labeled lymph nodes and lymph node metastasis in different lymph node regions of colorectal cancer, and to clarify the application value of carbon…
- Trial name
- CNP-CRC (NCT06783985)
- Where
- China
- Volunteers
- 146 people
- Sponsor
- Sir Run Run Shaw Hospital
Breast Cancer, Sentinel Lymph Node
Application of EndoScell Intraoperative Cellular Probing Technology for Early-Stage Breast Cancer
Sentinel Lymph Node Biopsy (SLNB) is a common surgical treatment for breast cancer and a primary method for assessing the pathological status of axillary lymph nodes.
- Conditions
- Breast Cancer, Sentinel Lymph Node, Frozen Section, Cytology
- Trial name
- EDGE (NCT06911528)
- Testing
- EndoScell Scaner (ES) novel intraoperative cellular probing technology
- Where
- China
- Volunteers
- 709 people
- Sponsor
- Fudan University
Malignant Neoplasm of Breast.
Discordant Hormonal Status of Breast Cancer.
The purpose of this study is to determine discordant hormonal status of primary breast tumor and metastatic breast cancer cells at regional lymph nodes in node positive breast cancer patients.
- Trial name
- NCT01943032
- Where
- Thailand
- Volunteers
- 105 people
- Sponsor
- National Cancer Institute, Thailand
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