Clinical trials: Macrosomia, open to volunteers
Macrosomia, Fetal, Large for Gestational Age
Fetal Clavicular Measurement to Predict Fetal Macrosomia
Macrosomia is associated with increased risks for both the mother and the baby, including complications during delivery, injuries, and even death. The accurate diagnosis of macrosomia is often difficult before birth.
- Conditions
- Macrosomia, Fetal, Large for Gestational Age, Shoulder Dystocia
- Trial name
- NCT06283277
- Testing
- Obstetric Ultrasound
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postpartum Urinary Incontinence, Postpartum Depression (PPD)
Prenatal Exercise Including Perineal Massage and Maternal-Neonatal Outcomes
The study is divided into three phases: Phase 1: Baseline survey to obtain an overall understanding of the current situation of voluntary participation in prenatal perineal massage.
- Conditions
- Postpartum Urinary Incontinence, Postpartum Depression (PPD), Neonatal Complications, Gestational Diabetes
- Trial name
- PEPM-RCT (NCT07314502)
- Testing
- Supervised prenatal exercise including antenatal perineal massage
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- South China Normal University
Large for Gestational Age (LGA), Pregnancy
Repeat Late GDM Testing and Cesarean Delivery Rates
The goal of this randomized trial is determine if re-testing for gestational diabetes in the third trimester after an ultrasound measurement of estimated fetal weight (EFW) or abdominal circumference greater than 90%ile decreases…
- Trial name
- NCT07708129
- Testing
- Glucose tolerance test and continuous glucose monitor
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Shauna F. Williams, MD
Macrosomia, Fetal, Gestational Diabetes Mellitus in Pregnancy
New Markers of Glycation to Predict Gestational Diabetes Mellitus and Macrosomia.
Gestational diabetes mellitus (GDM) increases the risk of macrosomia and other adverse pregnancy outcomes. Screening strategies are debated: universal vs.
- Trial name
- GLYCAGEST (NCT06048510)
- Testing
- Pregnant women
- Where
- France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Bordeaux
Gestational Diabetes
Role of HbA1c in Predicting Adverse Pregnancy Outcomes
This study aims to determine the reference value of HbA1c that can be used to predict adverse pregnancy outcomes. These adverse outcomes include LGA fetus, shoulder dystocia, caesarean section, pre-term birth, pre-eclampsia and…
- Trial name
- NCT06676254
- Where
- Malaysia
- Volunteers
- 195 people
- Sponsor
- National University of Malaysia
Body Composition, Feeding; Difficult, Newborn
Role of Body Composition in Large for Gestational Age Infants (LGA) With Oral Feeding Difficulty
Large for Gestational Age (LGA) infants have excess fat-mass (FM) proportion secondary to prolonged in utero exposure to an energy-rich environment.
- Conditions
- Body Composition, Feeding; Difficult, Newborn, Nutrition Disorder, Infant
- Trial name
- NCT04599010
- Testing
- Dietary intervention
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Neonatal Hypoglycemia, Gestational Diabetes
Accuracy of Interstitial Continuous Glucose Sensors in Neonates
Low blood sugar in newborns is common and if prolonged or untreated may place them at increased risk for later learning and behavior challenges.
- Conditions
- Neonatal Hypoglycemia, Gestational Diabetes, Maternal Obesity Complicating Pregnancy, Small-for-gestational Age
- Trial name
- NCT07133906
- Testing
- Continuous glucose monitoring, Cerebral near-infrared spectroscopy
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Macrosomia, Fetal Weight
Ultrasound Estimation of Fetal Macrosomia at Term: Diagnostic Accuracy Within 24 Hours of Delivery
Obstetric ultrasonography is now an essential tool for monitoring pregnancy. In France, three ultrasounds are recommended during a singleton pregnancy (at 12, 22, and 32 weeks of amenorrhea) to improve maternal and neonatal care.
- Trial name
- ECHO-MACRO (NCT07433751)
- Testing
- Ultrasound estimation of fetal macrosomia at 12 weeks of amenorrhea, Ultrasound estimation of fetal macrosomia at 22 weeks of amenorrhea, Ultrasound estimation of fetal macrosomia at 32 weeks of amenorrhea
- Where
- France
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Henri Duffaut - Avignon
Gestational Diabetes, Macrosomia, Fetal
Artificial Intelligence and Gestacional Diabetes
Artificial intelligence (AI) technology can assist medical teams in remote monitoring and continuing education of women with gestational diabetes (GDM), potentially improving adherence to interventions and impacting outcomes.
- Trial name
- NCT07345143
- Testing
- monitoring model for women with gestacional diabetes using pharmacological therapy
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- JOSE FERNANDO VILELA-MARTIN
Fetal Macrosomia, Intrauterine Growth Disorders (IUGR and Macrosomia)
Estimation of Fetal Weight by Measuring Abdominal Circumference, Abdominal Subcutaneous Soft Tissue Thickness, Femur Length and Mid-thigh Soft Tissue Thickness
Traditional methods for estimating fetal weight (EFW) often miss the mark because they focus on bone and circumference while ignoring fetal fat. This study proposes a more inclusive formula to fix that.
- Conditions
- Fetal Macrosomia, Intrauterine Growth Disorders (IUGR and Macrosomia), Intrauterine Growth Restriction (IUGR)
- Trial name
- NCT07575152
- Testing
- 3rd trimester ultrasound examination within 48-72 hours of delivery
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Assiut University
Childhood Overweight
Effects of Lifestyle Intervention on Childhood Outcomes in LGA Infants
Large-for-gestational-age (LGA) infants have a higher risk of metabolic disease later in life, and their postnatal growth in early childhood may be associated with long-term adverse outcomes.
- Trial name
- NCT04661449
- Testing
- Comprehensive lifestyle intervention
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Preterm Birth, Preeclampsia
The ROOT Study: Scaling the 'Standard of Care Plus' Obstetric Nutrition Model to Optimize Maternal and Infant Health
The 'Standard of Care Plus' ('PLUS') model in the ROOT Study consists of analyzing select micronutrient and gene variants of pregnant females to construct trimester-specific and personalized nutrition and lifestyle…
- Conditions
- Preterm Birth, Preeclampsia, Gestational Diabetes Mellitus (GDM), Small for Gestational Age (SGA)
- Trial name
- ROOT (NCT07559773)
- Testing
- 'Standard of Care PLUS'
- Volunteers
- 500 people
- Sponsor
- GrowBaby Life Project
Overweight and Obesity, Weight Loss
PRE-Pregnancy Weight Loss And the Reducing Effect on CHILDhood Overweight - Aarhus
The study is a single site parallel randomized controlled study. The study will be assessing the effect of a 10% pre-conceptional weight loss intervention vs a control group among healthy couples where the prospective mother is…
- Conditions
- Overweight and Obesity, Weight Loss, Pregnancy Related, Child Nutrition Sciences
- Trial name
- PREPARE CHILD (NCT05798494)
- Testing
- Weight loss intervention
- Where
- Denmark
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ulla Kampmann Opstrup
Small for Gestational Age Infant, Large for Gestational Age Infant
"Fetal gRowth AbnorMality dEtection Trial"
The present trial intends to assess the diagnostic accuracy of symphysis fundal height (SFH) as opposed to SFH combined with point of care ultrasound to measure the fetal abdominal circumference (POC-US-AC) in identifying small…
- Conditions
- Small for Gestational Age Infant, Large for Gestational Age Infant, Oligohydramnios, Polyhydramnios
- Trial name
- FRAME (NCT05043753)
- Testing
- Point of care ultrasound to measure the fetal abdominal circumference (POC-US-AC)
- Where
- 3 sites in Italy
- Volunteers
- 1,566 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Accuracy of Sonographic Vs MRI Fetal Weight Estimation
Comparison of Sonographic and MRI Weight Estimation in Fetuses with Suspected Macrosomia
The goal of this clinical trial is to compare the accuracy of sonographic vs. magnetic resonance fetal weight estimation in suspected fetal macrosomia in term pregnancy.
- Trial name
- NCT06898892
- Testing
- Fetal MRI
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya