Clinical trials: Malondialdehyde
Stress Oxidative
Natural Antioxidant Intake After Exercise Can Oxidative Stress in the Third Trimester of Pragnancy
Pregnancy is a condition that increased requirements of energy and oxygen, and if this condition is not maximally that can lead oxidative stress and produce free radicals which is affect in the pregnancy process.
- Trial name
- MDA (NCT04226183)
- Testing
- pregnancy workout
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Polycystic Ovary Syndrome, Chronic Periodontitis
Chronic Periodontitis and Polycystic Ovary Syndrome
Background: The aim of this study was to investigate the levels of malondialdehyde (MDA), total antioxidant status (TAS), 8-hydroxy-2´- deoxyguanosine (8-OHdG) in blood serum and saliva samples in female patients with chronic…
- Trial name
- NCT02954120
- Testing
- no intervention provided
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Heart Arrest, Sport Injury
Tour de Borobudur Troponin Study on Predictors and Synergistic Role of MDA and Hs-CRP Levels
Prospective observational study to determine predictors that related to cardiac troponin I (cTnI) release, malondialdehyde (MDA) and high sensitivity C Reactive Protein (hs-CRP) after Tour de Borobudur (TdB) 2017
- Conditions
- Heart Arrest, Sport Injury, Inflammatory Response, Oxidative Stress
- Trial name
- TdBTS (NCT03310450)
- Testing
- 140kms cycling
- Where
- Indonesia
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Universitas Negeri Semarang
Oxidative Stress
Turmeric Extract and Oxidative Stress in Muaythai Athletes and Sedentary Men
This study examined whether taking turmeric extract for 28 days affects oxidative stress and antioxidant defenses in healthy men who practice Muaythai and men who do not exercise regularly.
- Trial name
- NCT07904598
- Testing
- Turmeric Extract, Structured Muaythai Training
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Sinan Ağlar
Oxidative Stress, Inflammation
PsP Ganoderma Lucidum Supplementation and Biomarker Changes in Smokers
The goal of this randomized controlled clinical trial is to evaluate whether polysaccharide peptide (PsP) supplementation from Ganoderma lucidum can modulate biomarkers of oxidative stress, inflammation, nicotine exposure, and…
- Conditions
- Oxidative Stress, Inflammation, Cigarette Smoking
- Trial name
- PSPGL (NCT07316400)
- Testing
- PsP
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Brawijaya
Hyperlipidemia, Periodontitis, Gingivitis
PERIODONTAL DISEASE AND HYPERLIPIDEMIA
The investigators hypothesized that hyperlipidemia as an unfavourable levels of lipoprotein subfractions have deleterious impact on the development of periodontal infection by altering oxidative stres status of periodontal…
- Trial name
- NCT02808130
- Testing
- hyperlipidemia, periodontitis, gingivitis
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Oxidative Stress, Obesity
Acute Effect of Apple Cider Vinegar on Postprandial Plasma Malondialdehyde in Adult With Obesity
Research on the benefits of apple cider vinegar has tended to focus on its hypoglycemic effects and lipid profile changes during long-term consumption, without exploring its acute effects on oxidative stress during short-term…
- Trial name
- NCT07414875
- Testing
- apple cider vinegar
- Where
- Indonesia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
HELICOBACTER PYLORI INFECTIONS, Helicobacter Infection
Vonoprazan vs Proton Pump Inhibitor With Vitamin D or Probiotics Based Triple Therapy for Eradication of Helicobacter Pylori Infection
Helicobacter pylori is a Gram-negative, spiral-shaped bacterium that infects up to 50% of the world's population, residing in the gastric mucosa and using the mucus layer for protection from the stomach's high acidity.
- Conditions
- HELICOBACTER PYLORI INFECTIONS, Helicobacter Infection, Helicobacter Pylori Gastrointestinal Tract Infection, Helicobacter Pylori Infected Patients
- Trial name
- NCT07293910
- Testing
- Vonoparazan, Vitamin D, Probiotic
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Tanta University
Chronic Periodontitis
Effect of Scaling and Root Planing Along With Topical Application of Commercially Available Curcuma Longa Gel on Superoxide Dismutase and Malondialdehyde Levels in Saliva of Chronic Periodontitis Patients
Periodontitis is initiated by microbial biofilm but its progression is mediated by an abnormal host response to biofilm microorganisms.
- Trial name
- NCT02442453
- Testing
- Topical application of curenext gel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Elderly Individuals Aged 60 Years or Older, Mild Cognitive Impairment (MCI)
THE EFFECTS OF GAMBIR CATECHIN (UNCARIA GAMBIR ROXB) SUPPLEMENTATION ON COGNITIVE FUNCTION, EXPRESSION OF APP, MAPT, BDNF, IL-10, TGF-Β GENES, AND PLASMA MDA LEVELS IN THE ELDERLY.
Objective The primary objective of this clinical trial is to investigate the effects of gambir catechin administration on cognitive function, the expression of amyloid precursor protein (APP), microtubule-associated protein tau…
- Trial name
- NCT06604390
- Testing
- catechin extracts (health food), plasebo
- Where
- 2 sites in Fiji, Indonesia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Rahmi Novita Yusuf
Kidney Calculi
Allopurinol Effect on MDA,NO,KIM-1 Urine Levels, RI and Renal Elastography in Kidney Stone Patients Post ESWL
Extracorporeal shock wave lithotripsy (ESWL) is accepted as the first treatment choice for most urinary stones. Still, it has adverse effects on the kidneys.
- Trial name
- NCT05414669
- Testing
- Allopurinol Tablet 300 mg, Control Group
- Where
- Indonesia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- RSUP Prof. Dr. I.G.N.G. Ngoerahal
NIDDM
Spices Inhibit the Formation and Absorption of Malondialdehyde From Hamburger Meat
Polyphenols belong to the largest group of secondary metabolites produced by plants, mainly, in response to biotic or abiotic stresses such as infections, wounding, UV irradiation, exposure to ozone, pollutants, and other hostile…
- Trial name
- NCT01027052
- Testing
- Hamburger meat patty with salt, Hamburger meat patty with spice blend
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Gingivitis and Periodontal Diseases
Alpha-Lipoic Acid as an Adjunct to Non-Surgical Periodontal Treatment in Gingivitis
Gingivitis is an early and reversible form of periodontal disease characterized by an increased inflammatory response to dental biofilm.
- Trial name
- NCT07882394
- Testing
- Alpha-Lipoic Acid 200 mg, Alpha-Lipoic Acid 600 mg
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Biruni University
Antioxidants, Oxidative Stress
The Influence of Melatonin Supplementation in the Group of Persons Performing Competitive Sport.
The research aims to determine the impact of 30-day supplementation of melatonin on the antioxidative defense mechanisms and the release of markers of oxidative stress and inflammation in rowers and footballers undergoing…
- Conditions
- Antioxidants, Oxidative Stress, Inflammation, Lipid Peroxidation
- Trial name
- NCT03505411
- Testing
- melatonin supplementation
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Nicolaus Copernicus University
Neoplasms, Antioxidants
Oxidoreductive Balance and Lysosomal Activity in Cancer Patients.
The research aims to determine the parameters of oxidative stress and inflammatory processes and compare these parameters with the image obtained using positron emission tomography (PET) with 2-deoxy-2-[fluorine-18]fluoro…
- Conditions
- Neoplasms, Antioxidants, Oxidative Stress, Lipid Peroxidation
- Trial name
- NCT03470857
- Testing
- Patients
- Where
- 3 sites in Poland
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Nicolaus Copernicus University
Complementary Feeding Recommendation, Linear Programming,
Effect of Enhanced Counseling Using Complementary Feeding Recommendation Based on Linear Programming on Nutritional Status,Omega-3 Fatty Acids, Malondialdehyde, and Alpha-Tocopherol in Overweight Children in East Jakarta
The epidemic of pediatric obesity has become a public health burden in both developed and developing countries, due to its serious health consequences, including an increased risk of type 2 Diabetes Mellitus and heart disease.
- Conditions
- Complementary Feeding Recommendation, Linear Programming,, Nutritional Status, Omega-3 Fatty Acids
- Trial name
- NCT02592109
- Testing
- Enhanced Counseling using CFR based on Linear Programming
- Where
- Indonesia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Urine
Lipid Peroxidation in Workers Exposed to Al,Ga,In,As,and Sb in Optoelectronic Industry
To investigate whether exposure to Al, Ga, In, As, and Sb induces lipid peroxidation in humans. Whole blood and urine levels of 170 workers were analysed by use of ICP-MS.
- Trial name
- NCT00383981
- Where
- Taiwan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Type 2 Diabetes Mellitus, Chronic Periodontitis
The Effect Of Glycemic Control On Malondialdehyde, Glutathione Peroxidase, Glutathione And Paraoxonase
The aim of this study was to investigate the impact of glycemic control on clinical periodontal status, levels of malondialdehyde (MDA), glutathione peroxidase (GSH-Px), reduced glutathione (GSH) and paraoxonase (PON) activity in…
- Trial name
- NCT01467674
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Periodontitis, Periodontitis Stage III
Diode Laser-Assisted Periodontal Therapy Enhances Clinical Outcomes for Deep Periodontal Pockets in Smokers
This study investigated the adjunctive effects of diode laser therapy in smokers with severe periodontitis. Thirty-three patients were randomized to non-surgical periodontal therapy (SRP) with or without diode laser.
- Conditions
- Periodontitis, Periodontitis Stage III, Periodontal Disease, Diode Laser Therapy
- Trial name
- NCT07213752
- Testing
- Diode Laser Application in Deep Periodontal Pockets, Professional Mechanical Plaque Removal, Scaling and Root Planing
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Menstrual Irregularity, Menstrual Cycle Abnormal
Exploring the Complex Links Between Menstrual Irregularity and Cellular Markers
A cross-sectional study design was employed, involving 56 premenopausal participants with ages ranging from 20 to 49 years. Serum samples were collected during the early follicular phase, and levels of some biochemicals…
- Trial name
- NCT06339476
- Testing
- Serum ADMA, MDA and M30 levels mesurment
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University