Clinical trials: Management
Rhino Sinusitis
Herbal Tea Extract for Management of Rhinosinusitis
The objective of this phase I controlled clinical trial is to determine the safety and efficacy of Berry leaves \& Mango leaves mixture in symptomatic treatments on disease-related quality of life in adults with clinically…
- Trial name
- NCT07534280
- Testing
- mango leaves extract, local steroids, nasal saline
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Deraya University
Asthma Chronic
Use of Aptar Digital Health's Respiratory Disease Management Platform for Asthma
The United Kingdom has a high prevalence of asthma (over 12%) and some of the worst health outcomes in Europe. The management of respiratory disease and associated patient outcomes has long been an area of focus and improvement…
- Trial name
- NCT06364527
- Testing
- Aptar Digital Health respiratory disease management platform
- Where
- United Kingdom
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- CoheroHealth
Postoperative Pain, Regional Anesthesia
Comparison of Continuous Fascia Iliaca Compartment Block With Continuous PENG Block in Total Hip Replacement Cases
Adequate pain management after total hip arthroplasty (THA) is crucial for early ambulation and patient satisfaction. However, due to the hip joint's innervation complexity, the optimal regional analgesia technique for THA…
- Conditions
- Postoperative Pain, Regional Anesthesia, Pain Management, Total Hip Arthroplasty
- Trial name
- PENG (NCT06806865)
- Testing
- Periarticular nerve group block (PENG), Continuous supra-inguinal fascia iliaca compartment block (SIFICB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Dermatitis, Knowledge, Attitudes, Practice
Impact of Combining Incontinence-associated Dermatitis Prevention and Management Course and Directive Wheel Chart
Background: Knowledge, attitudes, and behaviors regarding the prevention and care of incontinence-associated dermatitis (IAD) need to be enhanced through educational training.
- Trial name
- NCT06835192
- Testing
- Experimental group, Control Group
- Where
- Taiwan
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Labor Pain, Epidural
A Comparison Between 2 Methods of Local Anesthetic Administration for Maintaining Labor Analgesia After Dural Puncture Epidural
Intermittent epidural bolus technique opens a new era of interest for maintaining labor anlagesia. The study examines programmed intermittent epidural bolus technique on a scheduled basis to provider-administered bolus anlgesia…
- Conditions
- Labor Pain, Epidural, Pain, Labor
- Trial name
- NCT05034211
- Testing
- Programmed intermittent bolus epidural, Provider administered analgesia on patient request
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aretaieio Hospital
Adolescent Dysmenorrhea
Adolescent Dysmenorrhea : Prevalence, Severity, Experience and Management in the Use of Medication in High School Girls in Ille-et-Vilaine
Dysmenorrhea or painful menstruation is a common symptom of menses. Dysmenorrhea is defined as a painful, cramping sensation in the lower abdomen or back associated with menstrual periods and is classified into primary and…
- Trial name
- DAPsvs (NCT04007471)
- Testing
- Anonymous survey
- Where
- France
- Volunteers
- 979 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
HIV Prevention
Evaluation of a Differentiated Point-of-care Active Case Finding & Management Model to Eliminate Mother-to-Child Transmission of HIV in Malawi
Purpose: To conduct a hybrid effectiveness-implementation stepped-wedge trial to: 1. Estimate the effect of the PAC-Man model, compared to SOC, on the proportion of infants who receive timely EID testing. 2.
- Trial name
- PAC-Man (NCT06493357)
- Testing
- PAC-Man, Standard of Care
- Where
- 3 sites in Malawi
- Volunteers
- 2,426 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Atrophic Scar
Safety and Efficacy of Autologous Adipose-derived Mesenchymal Stem Cells Therapy in Adults With Atrophic Scars
The purpose of this clinical trial was to evaluate the safety and efficacy of a single administration of TRTP-101 in adults with atrophic scars.
- Trial name
- NCT07474467
- Testing
- TRTP-101
- Where
- South Korea
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- CellinCells
Hepatic Insufficiency
A Study to Test How Iclepertin is Taken up in the Blood of People With and Without Liver Problems
This study is open to people with and without liver problems. People can join the study if they are 18 to 79 years of age and have a body mass index (BMI) between 18.5 and 35 kg/m2.
- Trial name
- NCT05731895
- Testing
- Iclepertin
- Where
- Germany
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Educational Activities
A Comparison of Clinical Simulation and Classical Learning for Airway Management in Medical Students
Multiple studies have shown clinical simulation benefits over classical learning method. Research on simulation of airway management has focused on endotracheal intubation training, while research on ventilation via facemask is…
- Trial name
- NCT03071367
- Testing
- Clinical Simulation
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Fundación Santa Fe de Bogota
Obesity
Whey Protein, Resistance Training, and Changes in Body Composition
The objective of this project is to determine the effect of 9 months of progressive resistance training with daily whey protein supplements on the body composition (changes in muscle and fat) in young adults.
- Trial name
- NCT01186536
- Testing
- Whey Protein supplement, Soy Protein Supplement, Carbohydrate supplement
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Solid Tumor
BA Study of IMP4297 (20mg vs 10mg) in Healthy Male Subjects
An open-label, randomized, single-dose, 2-way crossover study to compare the bioavailability of two IMP4297 formulations (20 mg capsules and 10 mg capsules) after single oral administration of 100 mg IMP4297 under fasted…
- Trial name
- NCT04351165
- Testing
- IMP4297
- Where
- Australia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Impact Therapeutics, Inc.
Pulmonary Hypertension
Characterization and Detection of Prolonged Endothelin Receptors Antagonists Administration
Endothelin receptors antagonists (ERA), such as bosentan and ambrisentan, are a class of vasoactive drugs that have been developed for the treatment of pulmonary arterial hypertension.
- Trial name
- ERAATH (NCT01352065)
- Testing
- Bosentan, Ambrisentan
- Where
- Serbia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Center for Health Sciences, Serbia
Postpartum Hemorrhage
Active Versus Expectant Management of the Third Stage of Labor
The purpose of this study is to determine if giving oxytocin immediately after delivery causes less bleeding, transfusion needs and hastens delivery of placenta.
- Trial name
- NCT00473707
- Testing
- Active management of the third stage of labor, Expectant management of the third stage of labor, Oxytocin and gentle cord traction with fundal massage
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Knee Discomfort, Knee Pain Chronic
Evaluation Study for the "Jockey Club E-Generation: Impact Extension Project for Chronic Knee Pain Management"
Objectives: This study aims to evaluate the effectiveness of the "Jockey Club E-Generation: Impact Extension Project for Chronic Knee Pain Management", with a view to developing sustainable strategies of self-management on…
- Trial name
- NCT06569836
- Testing
- 12-week intervention, 12-week attention control
- Where
- Hong Kong
- Volunteers
- 858 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Healthy
A Study of JNJ-80202135 in Healthy Chinese Adult Participants
The purpose of this study is to assess the pharmacokinetic (PK) of nipocalimab following single intravenous (IV) administration in healthy Chinese participants.
- Trial name
- NCT05151692
- Testing
- Nipocalimab
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
HIV Infections
A Study of Zidovudine in Infants Exposed to the HIV Before or Soon After Birth
To determine if intravenous (IV) and oral zidovudine (AZT) can be safely given to children aged 1 day to 3 months who were born to mothers with an HIV infection. Also to determine the correct dose of AZT for young children.
- Trial name
- NCT00001007
- Testing
- Zidovudine
- Where
- 6 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy
Bioequivalence Study of Telmisartan Between Telmisartan 80 mg/Amlodipine 5 mg/Hydrochlorothiazide 12.5 mg (T80/A5/H12.5 mg) Fixed-dose Combination (FDC) Tablet and T80/H12.5 mg Tab and A5 mg (Encap A2.5 mg Tab x2) Concomitant Use
To investigate the steady state pharmacokinetics of different formulation of Telmisartan, Amlodipine, and Hydrochlorothiazide (HCTZ).
- Trial name
- NCT02129192
- Testing
- Amlodipine 5mg capsule, T80/H12.5 mg FDC tablet, T80/A5/H12.5 mg FDC tablet
- Where
- Japan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
To Assess the Bioequivalence of Two Pacritinib Drug Product Formulations and FMI Formulation Following Oral Administration in Healthy Subjects
A Phase 1, Open-Label, Single-Dose, Randomized, 2-Period Crossover Study to Assess the Bioequivalence of Two Pacritinib Drug Product Formulations (Phase 3 Clinical Trial [P3CT] Formulation [Reference] and Final Market Image [FMI]…
- Trial name
- NCT02823171
- Testing
- Treatment A: 400 mg Pacritinib P3CT, Treatment B: 400 mg of pacritinib FMI
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- CTI BioPharma
Urinary Incontinence, Sarcopenia
The Urinary Incontinence Treatment Study
Investigators plan a prospective cohort study with an adaptive design based on physical function status. The design will involve tracking the number of women recruited with physical function impairment and those without any…
- Trial name
- UNITS (NCT03057834)
- Testing
- Pelvic floor muscle exercise
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
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