Clinical trials: Mandibular Diseases
Bruxism, Temporomandibular Joint Disorders
Aspects Associated With Obstructive Sleep Apnea, Bruxism and Orofacial Pain
This study evaluated the influence of the sleep bruxism (SB), awake bruxism (AB) and obstructive sleep apnea syndrome (OSAS) on the signs and symptoms of temporomandibular disorders (TMD).
- Conditions
- Bruxism, Temporomandibular Joint Disorders, Obstructive Sleep Apnea Syndrome
- Trial name
- NCT03766464
- Testing
- Evaluation of TMD and pain sensitivity, Evaluation of SB, Evaluation of AB
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Postoperative Pain, Trismus
Effect of CGF on Short Term Clinical Outcomes After Partially Impacted Mandibular Third Molar Surgery
The aim of this study was to evaluate the effectiveness of concentrated growth factor (CGF) on soft tissue healing and postoperative side effects following third molar surgery.
- Conditions
- Postoperative Pain, Trismus, Edema
- Trial name
- CGF (NCT03913884)
- Testing
- Concentrated growth factor, Non-Concentrated growth factor Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Bone Loss, Bone Lesion
Hyaluronic Acid +Hydroxyapatite Vs Hydroxyapatite in Bone Regeneration
Evaluation of the effect of hyaluronic acid with hydroxyapatite versus hydroxyapatite alone on bone regeneration following enucleation of mandibular odontogenic cyst.
- Trial name
- NCT05957926
- Testing
- hyaluronic acid added to hydroxyapetite, Hydroxyapatite alone
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mandible Fracture
Stability of Angle Fracture Fixation With (K) Shaped Titanium Miniplates Versus Two Miniplates
In patients with angle fracture , will the (K) shaped titanium miniplates provide more stable fixation than two conventional miniplates? Many studies have been conducted to compare between different techniques of fixation used in…
- Trial name
- NCT03839368
- Testing
- fixation of angle fracture
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Furcation Defects
Rosuvastatin Gel With 1:1 Mixture of Platelet-rich Fibrin and Bone Graft in Mandibular Degree II Furcation Defects
Rosuvastatin (RSV) is a new synthetic, second-generation, sulfur-containing, hydrophilic statin, that stimulate bone formation in critical-size cortical bone defects adjacent to titanium implants, when administered locally in…
- Trial name
- NCT02369250
- Testing
- Rosuvastatin, platelet rich fibrin
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Dystonia, Drug Induced Dystonia
Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
This research involves retrospective and prospective studies for clinical validation of a DystoniaNet deep learning platform for the diagnosis of isolated dystonia.
- Conditions
- Dystonia, Drug Induced Dystonia, Parkinson Disease, Essential Tremor
- Trial name
- NCT05317390
- Testing
- DystoniaNet-based diagnosis of isolated dystonia
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar
Comparison of PRF and Corticosteroids in Impacted Third Molar Surgery
This prospective, randomized interventional study aims to compare the postoperative effects of standard treatment (control), platelet-rich fibrin (PRF), and PRF combined with corticosteroid treatment in patients undergoing…
- Conditions
- Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar, Impacted Wisdom Tooth
- Trial name
- NCT07742826
- Testing
- Platelet-rich fibrin (PRF), Dexamethasone, Amoxicillin/Clavulanic Acid
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Final International University
Alveolar Bone Loss, Bone Graft Failure
Ridge Preservation In Mandibular Molars Using Mixture Of ABB And Autogenous Particulate VS Sticky Bone
Histological Measurement Comparing the density of the new bone formed during socket preservation technique using a Mixture of Anorganic Bovine Bone(ABB) And Autogenous Particulate vs a Mixture of Injectable Platelets Rich Fibers…
- Conditions
- Alveolar Bone Loss, Bone Graft Failure, Alveolar Bone Resorption
- Trial name
- NCT03584997
- Testing
- ABB And Autogenous Particulate, PRF, ABB & Autogenous Particulate
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cleft Lip and Palate, Maxillary Hypoplasia
Cleft Orthognathic Surgery Versus Distraction Osteogenesis - Which is Better?
Cleft lip and palate patients normally present with a sunken face due to collapse in the middle part of the face and inability of the upper and lower teeth to meet during chewing.
- Trial name
- NCT00930124
- Testing
- Orthognathic surgery, Distraction osteogenesis
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Class III Malocclusion, Maxillary Deficiency
Evaluation of Pain and Functional Impairments When Treating Class III Malocclusion Using Two Treatment Procedures
A clinical examination of each recalled candidate patient will be carried out at Adib Al Lahham Centre at the Ministry of Health Damascus to ensure that he/she meets the inclusion criteria.
- Trial name
- NCT06877780
- Testing
- RMR with SME, BAIMT with RME
- Where
- Syria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Damascus University
Cleft Palate, Maxillary Hypoplasia
Does Use of Rigid Fixation After Removing Distraction Osteogenesis Device Reduce the Relapse?
patients were enrolled by the inclusion criteria and were undergo lefort 1 maxillary osteotomy. after the latency phase the distraction was done in anterior- posterior vector.
- Conditions
- Cleft Palate, Maxillary Hypoplasia, Maxillary Retrognathism
- Trial name
- NCT02350803
- Testing
- mini plate
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Temporomandibular Disorders
Oxidative Stress and Opiorphin in Temporomandibular Disorders
The objective of this study is to quantify salivary oxidative stress biomarkers in patients with temporomandibular disorders and to quantify recently isolated endogenous peptide opiorphin in saliva of these patients.
- Trial name
- ROStrO-TMD (NCT03029494)
- Testing
- stabilization splint, Vitamin C
- Where
- Croatia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Croatian Science Foundation
Temporomandibular Disorder
Platelet-rich Plasma Injection for Temporomandibular Disorders
Temporomandibular disorder (TMD) involves the temporomandibular joint (TMJ) and surrounding structure, causing problems including myofascial pain and joint degeneration. TMD is mostly seen in the age group of 18 to 44.
- Trial name
- NCT04127942
- Testing
- platelet-rich plasma injection therapy of TMD
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Mandibular Fractures
Computer Guided Screw Holes Locating Guide and Custom-made Plates
Preoperative CT. Virtual reduction of broken segments on software. Gain occlusion. Design surgical screw holes locating guide. Design the custom-made plates. Print the screw holes locating guide and the custom-made plate.
- Trial name
- NCT05647460
- Testing
- computer guided screw holes locating guide and custom-made plates, conventional plates
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Trismus, Edema
Management of Postoperative Complications After Mandibular Third Molar Extraction Using Submucosal Triamcinolone Injection, Kinesiology Taping, and Standard Care
The surgical removal of impacted lower wisdom teeth (mandibular third molars) frequently leads to uncomfortable postoperative symptoms, including pain, facial swelling (edema), and restricted jaw movement (trismus).
- Conditions
- Trismus, Edema, Pain
- Trial name
- NCT07719270
- Testing
- Triamcinolone Acetonide 10mg, Kinesiology Taping, Standard Postoperative Care
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Allama Iqbal Medical College
Bone Loss, Regenerative Inflammation
Osteogenic Action of a Biphasic Bioceramic With Statin in a Third Molar Extraction Model
The clinical study aims to assess the osteogenic effects of Galibone+ in bone regeneration post-extraction of impacted mandibular third molars.
- Trial name
- Galibone (NCT06338241)
- Testing
- Biphasic bioceramic of tricalcium phosphate and hydroxyapatite with simvastatin, Bovine Hydroxyapatite
- Where
- 2 sites in Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mario Pérez Sayáns
Orthodontic Appliance
Occlusal Bite Force Changes After Surgical Correction of the Increased Vertical Dimension
The aim of this study was to record the OBF changes after surgical correction of mandibular prognathism in patients with or without increased vertical skeletal dimensions at different time intervals (T0: before surgery; T1: at…
- Trial name
- NCT04376645
- Testing
- Mandibular Setback with maxillary impaction, Mandibular setback only
- Where
- Jordan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Temporomandibular Disorder, Temporomandibular Joint Dysfunction
Trauma Exposure and Childhood Trauma in Temporomandibular Joint Disorders
Temporomandibular disorder is a multifactorial condition that involves the temporomandibular joint, masticatory muscles, and surrounding structures and is influenced by biological, psychological, and social factors.
- Conditions
- Temporomandibular Disorder, Temporomandibular Joint Dysfunction, Trauma Exposure, Childhood Traumas
- Trial name
- NCT07292103
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Gulseren Demir Karakilic
Overjet, Dental
Sleep, Upper Airway and Dental Occlusion in Children With Large Overjet
This project examines sleep (e.g. prevalence of obstructive sleep apnea(OSA)), dimension of upper airway, jaw function, well-being and quality of life in children with large overjet compared to a control group.
- Trial name
- NCT04964830
- Testing
- Orthodontic treatment with functional appliance (MAD)
- Where
- Denmark
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
TMD, TMD/Orofacial Pain
Treatment Outcomes in Patients With Muscular Temporo-mandibular Joint Disorders
The aim of the present study was to assess the treatment outcomes in patients affected by M-TMDs in terms of pain scores assessed with pressure pain threshold (PPT).
- Trial name
- NCT06339736
- Testing
- Questionnaires administered to all study participants
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Pisa