Clinical trials: Mandibular Dysfunction
Temporomandibular Disorder, Facial Pain
Role of the Endogenous Opioid System Underlying Modulation of Experimental Pain
The aim of this proposal is to characterize pain inhibition in healthy controls and Temporomandibular Disorder (TMD) patients with two models of endogenous pain modulation (off-set analgesia; conditioned pain modulation), and to…
- Trial name
- NCT01327326
- Testing
- Naltrexone
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Temporomandibular Joint Disorders
Long-term Safety and Performance of Materialise's Patient-specific TMJ System.
This is a long-term (10 years), retrospective-prospective, observational, single-arm, monocenter study of patients to be treated with the Materialise TMJ Total Arthroplasty System for TMJ replacement.
- Trial name
- NCT06951178
- Testing
- TMJ Total Arthroplasty System (TMJ System)
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Materialise
Temporomandibular Joint Disorders
Impact of Orthodontic Treatment on the Temporomandibular Joints (TMJ) Assessed by Modjaw
The aim of the study is to assess the correlation between orthodontic treatment and temporomandibular joint (TMJ). For that, an evaluation with a virtual articulator (Modjaw) is carried out before and after the treatment.
- Trial name
- EMDJW (NCT05710952)
- Testing
- Review by Modjaw
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Montpellier
Temporomandibular Disorders (TMDs)
Diagnostic Study Accuracy of Jaw Motion Analyzer(JMA) Versus Research Diagnostic Criteria(RDC/TMD) and Magnetic Resonance Imaging(MRI) for Temporomandibular Disorders Among Patients With Chronic Orofacial Pain.
The goal of this diagnostic accuracy study is to determine the diagnostic accuracy of jaw motion analyzer(JMA) in terms of sensitivity and specificity with target cut of points used by valid reference standards which will be the…
- Trial name
- NCT07486609
- Testing
- The Jaw Motion Analyzer (JMA, Zebris, Germany) as the index test, Research Diagnostic Criteria for Temporomandibular Disoders, Magnetic Resonance Imaging
- Where
- Egypt
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Cairo University
Temporomandibular Dysfunction
Temporomandibular Joint Dysfunction in Patients With Traumatic Brain Injury
Trauma, neurological disorders and psychological problems, which are the etiological factors of temporomandibular joint dysfunction, can be seen in patients with traumatic brain injury.
- Trial name
- NCT05572541
- Testing
- Fonseca questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Konya Beyhekim Training and Research Hospital
TMD/Orofacial Pain, Muscle Spasm
Dry Needling for Temporomandibular Disorder
This randomized controlled trial investigates the clinical effectiveness of dry needling in individuals with myofascial temporomandibular disorder (TMD).
- Trial name
- DN-TMD (NCT07123883)
- Testing
- Dry Needling
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Atlas University
Temporomandibular Joint Dysfunction, TMD
Effects of Core Strengthening Exercises for Treating TMD
Temporomandibular disorders (TMD) are commonly managed with non-invasive interventions such as manual therapy, therapeutic exercise, relaxation techniques, and patient education.
- Conditions
- Temporomandibular Joint Dysfunction, TMD, TMJ Internal Derangement, Myofascial Pain
- Trial name
- NCT07226505
- Testing
- Experimental: Group 1: Core Strengthening, Group 2: Standard TMD PT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Loyola University
Temporomandibular Joint Disorders
Nasal Septum Autologous Chondrocytes Transplantation for Condylar Resorption After Orthognathic Surgery
This clinical study has as main objective to evaluate if the Nasal Septum Autologous Chondrocytes Transplantation for Condylar Resorption is safe and effective in the treatment of degenerative lesions of temporomandibular joint…
- Trial name
- NCT03137914
- Testing
- Autologous chondrocyte transplantation, orthognathic surgery
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Faculdade de Medicina de Petrópolis Faculdade Arthur Sá Earp Neto
Temporomandibular Disorder
Relationship Between Cervical Pain and Temporomandibular Dysfunction Craniovertebral Angle, Jaw Functional Limitation and Cervical Mobility
The aim of this study is to examine temporomandibular dysfunctions, jaw functional limitation, cervical mobility and craniovertebral angles and possible relations between individuals with cervical pain and individuals without…
- Trial name
- TMJ (NCT06623552)
- Testing
- Neck Pain and Disability Scale (NPDS), Fonseca Anamnestic Index (FAI), Evaluation of Jaw Functional Limitation
- Where
- Turkey (Türkiye)
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Temporomandibular Joint Disease
Effect of Emg-Biofeedback and Multimodal Exercise on Temporomandibular Joint Dysfunction
Temporomandibular joint dysfunction (TMD) is a multifactorial musculoskeletal disorder affecting the masticatory muscles, temporomandibular joint, and related structures, characterized by pain and functional limitations.
- Trial name
- NCT07577687
- Testing
- Multimodal physiotherapy program, EMG-Biofeedback
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Yuzuncu Yil University
Temporomandibular Joint Disorders
Validation of a Standardized Tool for Evaluation Function of Patients With TMD
Temporo-Mandibular Disorders (TMD) are the reason for consultation on more common in maxillofacial. However, there is no consensus on their care.
- Trial name
- DTM-SCORE (NCT03871608)
- Testing
- Examination of functional etiologies on DTM Disorders, Assessment of symptoms on DTM Disorders
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Temporomandibular Joint Disorders, Bruxism
Botox for Treatment of TMJ Disorder With Bruxism
Hypothesis: Myofascial temporomandibular joint disorder and related symptoms are associated with mandibular condyle and temporal fossa overloading secondary to temporalis and masseter muscle hyperactivity and spasm This study…
- Conditions
- Temporomandibular Joint Disorders, Bruxism, Temporomandibular Joint Dysfunction Syndrome, Myofascial Pain Dysfunction Syndrome, Temporomandibular Joint
- Trial name
- TMJ (NCT02202070)
- Testing
- onabotulinumtoxinA
- Where
- United States
- Sponsor
- Washington University School of Medicine
Dystonia, Drug Induced Dystonia
Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
This research involves retrospective and prospective studies for clinical validation of a DystoniaNet deep learning platform for the diagnosis of isolated dystonia.
- Conditions
- Dystonia, Drug Induced Dystonia, Parkinson Disease, Essential Tremor
- Trial name
- NCT05317390
- Testing
- DystoniaNet-based diagnosis of isolated dystonia
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Temporomandibular Disorder, Pathophysiology
Consequences of Temporomandibular Disorder on Balance Control
To evaluate the effects of the temporomandibular disorder (TMD) and its therapeutic care on postural control in somato-sensory and visual sensitization compared to control subjects matched on age, sex and lifestyle.
- Conditions
- Temporomandibular Disorder, Pathophysiology, Therapy
- Trial name
- DAM (NCT03283839)
- Testing
- Posturography
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Temporomandibular Disorders (TMD), Orofacial Pain
Telemonitoring for TMD-Related Pain
This prospective randomized clinical trial evaluates the effectiveness of a structured telemonitoring protocol as an adjunct to conservative management in patients with temporomandibular disorder (TMD)-related orofacial pain.
- Conditions
- Temporomandibular Disorders (TMD), Orofacial Pain, Myofacial Pain Syndromes, Myalgia of Mastication Muscle
- Trial name
- NCT07764770
- Testing
- Structured Telemonitoring, Conservative Management
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University Magna Graecia
Molar Incisor Hypomineralization
The Effect of Molar Incisor Hypomineralisation on the Stomatognathic System
This study aims to examine whether children with Molar Incisor Hypomineralization (MIH) are more likely to have problems with the jaw joint and chewing muscles.
- Trial name
- NCT06951139
- Testing
- Ultrasound and Shear Wave Elastography
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ozge Gungor
Temporomandibular Disorder, Neck Pain
Effect of Manual Therapy on Temporomandibular Joint Dysfunction
Temporomandibular disorders (TMD) are multifactorial conditions involving the temporomandibular joint and masticatory muscles, often presenting with pain and functional limitations.
- Trial name
- NCT07210957
- Testing
- Manual Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Abant Izzet Baysal University
Temporomandibular Disorders (TMD)
Safety and Efficacy of BHV-3000 (Rimegepant) Orally Disintegrating Tablet for Acute Treatment of Temporomandibular Disorders
The purpose of this study is to compare the efficacy and safety of rimegepant versus placebo in the acute treatment of Temporomandibular Disorders (TMD), which are medical conditions involving the temporomandibular joint (the…
- Trial name
- NCT05262517
- Testing
- Rimegepant
- Where
- 32 sites in United States
- Volunteers
- 126 people
- Sponsor
- Pfizer
Temporomandibular Disorders
Temporomandibular Disorders With and Without Chronic Neck Pain
Temporomandibular disorders (TMD) are common musculoskeletal conditions frequently accompanied by cervical dysfunction. Although previous studies have demonstrated associations between cervical impairments and temporomandibular…
- Trial name
- NCT07750743
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Ankylosing Spondylitis
Prevalence of Temporomandibular Joint Dysfunction in Patients With Ankylosing Spondylitis
This study included 113 patients diagnosed with ankylosing spondylitis and 110 healthy volunteers. Participants in both groups were evaluated using the 'Diagnostic Criteria for Temporomandibular Disorders (DC/TMD)' diagnostic…
- Trial name
- NCT05839925
- Testing
- Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) Axis I and II
- Where
- Turkey (Türkiye)
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital