Clinical trials: Mandibular Reconstruction
Oral Surgical Procedures, Surgery, Oral
Standardized Osteotomy Guides for Free Flap Reconstruction of Continuous Defects of the Jaws - a Simplified Method
The aim of the present project is to evaluate the outcome from reconstruction of the jaws, with a standardized simplified technique, after a continuous defect.
- Conditions
- Oral Surgical Procedures, Surgery, Oral, Mandibular Reconstruction
- Trial name
- NCT05715359
- Testing
- Reconstruction
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Lund University Hospital
Tumor, Facial Fracture
A Post Market Clinical Follow-up Study on Biomet Microfixation HTR PEKK (Midface), Facial & Mandibular Plates.
This study will address medical devices manufactured by Biomet Microfixation (d.b.a. Zimmer Biomet) designed for fixation and stabilization of the facial and mandibular skeleton.
- Conditions
- Tumor, Facial Fracture, Mandibular Fractures, Fibrous Dysplasia
- Trial name
- NCT04931056
- Testing
- Titanium Facial Plates, Titanium Mandibular Plates, Add-on Condyle
- Where
- Argentina
- Volunteers
- 91 people
- Sponsor
- Zimmer Biomet
Oral Tumor
Vascularized Free Fibula Flap and Computer-guided Implant Surgery
The rehabilitation of patients affected by defects of the jaws after tumor resection is still very challenging. Resection can lead to significant facial deformity, impaired oral functions such as speech, swallowing, saliva…
- Trial name
- NCT01561534
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- University of Bari
Segmentation; Bone
Accuracy of Open-source Software in Semi-automatic 3-Dimensional Reconstruction of the Mandible
Concomitant to the evolution of CBCT devices, several post-processing software packages were developed for producing 3D-printed models of anatomical structures.
- Trial name
- NCT05055986
- Testing
- Semiautomatic segmentation of open-source software
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mandibular Reconstruction, Dental Implant
Simultaneous Dental Implant in Free Vascularized Bone Flaps for Jaw Reconstruction
After jaw resection, free vascularized bone flaps are frequently used for repairing maxillofacial defects. Simultaneous dental implantation is more preferable to secondary implantation as it saves the patients from going through…
- Conditions
- Mandibular Reconstruction, Dental Implant, Free Tissue Flaps, Jaw Neoplasms
- Trial name
- NCT05405179
- Testing
- Simultaneous dental implantation
- Where
- Hong Kong
- Volunteers
- 25 people
- Sponsor
- The University of Hong Kong
Mandible Tumor, Mandibular Injuries
Evaluation of EpiBone-CMF for Mandibular Ramus Reconstruction
EpiBone-Craniomaxillofacial (EB-CMF) is an autologous, anatomically shaped bone graft created specifically for the patient's defect, using the patients own adipose-derived mesenchymal stem cells.
- Conditions
- Mandible Tumor, Mandibular Injuries, Mandible; Deformity
- Trial name
- EB-CMF (NCT03678467)
- Testing
- EB-CMF
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- Epibone, Inc.
Free Tissue Transfer, Mandible Reconstruction
Traditional Versus Computerized Mandibular Reconstruction
This study will test the accuracy of computerized custom mandibular reconstruction to traditional methods of mandibular reconstruction using a vascularized osteocutaneous fibula flap.
- Conditions
- Free Tissue Transfer, Mandible Reconstruction, Computerized Customization
- Trial name
- NCT02913807
- Testing
- Customized Jigs and Plates, Hand Contoured Osteotomies and Reconstruction Bars
- Where
- United States
- Sponsor
- Boston Medical Center
Mandibular Resection, Mandibular Reconstruction* / Methods
Patient-specific Reconstruction Plate for Segmental Mandibular Defects
The mandible's horseshoe-shaped anatomy makes the reconstruction of segmental defects a challenging procedure. Conventional reconstruction typically relies on alloplastic plates to bridge bony stumps; however, these require…
- Conditions
- Mandibular Resection, Mandibular Reconstruction* / Methods, Mandibular Reconstruction
- Trial name
- NCT07320924
- Testing
- Patient specific reconstruction plate
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Alexandria University
Mandibular Tumors
Aesthetic Reconstruction of Onco-surgical Mandibular Defects Using FFF With and Without CAD/CAM Customized Cutting Guide
The purpose of this study is to compare Aesthetic results and operation time of free fibular flap with and without CAD/CAM customized osteotomy guide for reconstruction of mandibular defects.
- Trial name
- NCT03757273
- Testing
- FFF with CAD/CAM customized cutting guide, FFF without customized cutting guide
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Mandibular Neoplasms, Maxillary Neoplasms
Three-Dimensional Printing of Patient-Specific Titanium Plates in Jaw Surgery: A Pilot Study
Medical titanium plates are routinely used in fixing mobilized bone segments in jaw surgeries. Generally these plates are commercialized with standard construction specifications.
- Conditions
- Mandibular Neoplasms, Maxillary Neoplasms, Dentofacial Deformities, Maxillofacial Injuries
- Trial name
- 3DJP16 (NCT03057223)
- Testing
- 3D-printed patient-specific titanium plates
- Where
- Hong Kong
- Volunteers
- 96 people
- Sponsor
- The University of Hong Kong
Mandibular Injuries
Accuracy and Outcome of Computer-assisted Surgery for Bony Micro-vascular Reconstruction in the Head and Neck Region
Background: Functional and aesthetic reconstruction of mandibular defects due to tumour invasion, osteoradio- or chemonecrosis or trauma are challenging.
- Trial name
- NCT03054012
- Volunteers
- 30 people
- Sponsor
- AZ Sint-Jan AV
Bone Augmentation
Reconstruction of Atrophic Maxillary Ridges Using Mandibular Blocks With and Without Coverage Using Collagen Membrane
Is the use of collagen membrane on top of particulate bone mixture covered by onlay bone block in Maxilla better than the use of mixture of particulate bone covered by onlay bone block without the use of collagen membrane, in…
- Trial name
- NCT04462575
- Testing
- Onlay bone block covered using collagen membrane, Onlay bone block without collagen membrane
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Otorhinolaryngologic Diseases
Reconstruction Implant Bone After Removal Using Porous Titanium Prosthesis
This trial will study the reconstruction of the anterior part of the mandible and the adjacent soft tissue parts by a mandibular prosthesis made in porous titanium, associated or not, to a latissimus dorsi or pectoral flap, to…
- Trial name
- NCT00213837
- Testing
- Mandibular prosthesis made of a new highly biointegratable material
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Strasbourg, France
Mandibular Injuries
Virtual Surgical Planning of Mandibular Reconstruction Using Custom Made Plate and Split Rib Bundle Bone Graf
In mandibular reconstruction, computer-assisted procedures, including virtual surgical planning (VSP) and Custom-made implants, have become an integral part of routine clinical practice.
- Trial name
- NCT07551154
- Testing
- ustom made plate and split rib bundle bone graft using virtual surgical planning
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Jaw Deformity
Evaluation of "Tent-Pole" Grafting Technique for Reconstruction of Mandibular Ridge Vertical Defects
The aim of this study is to evaluate clinically and radio-graphically the efficiency of "Tent- Pole "grafting technique for reconstruction of anterior or posterior mandibular ridge defects using synthetic bone graft and Platelet…
- Trial name
- NCT04192851
- Testing
- Tent Pole Technique
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Nourhan M.Aly
Mandible Reconstruction
Assessment of Facial Symmetry Following Fibula Free Flap Fixated in a Prosthetically Favorable Position Versus the Inferior Border Position for Mandibular Reconstruction
The study aims to evaluate facial symmetry outcomes after mandibular reconstruction using fibula free flaps, comparing two fixation techniques: the prosthetically favorable position (alveolar level) and the conventional position…
- Trial name
- NCT06790628
- Testing
- Fibula free flap
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Cairo University
Fixation of Double Barrel Vascularized Fibula
3D Titanium Miniplates Versus 3D Titanium Mesh Method of Fixation for Double Barrel Vascularized Fibular Graft
The double barrel fibula flap presents many advantages such as adequate, constant geometry, proper dimensions for implant placement, double periosteal and medullary blood supply allowing multiple osteotomies, correct contouring…
- Trial name
- NCT04704167
- Testing
- fixation of double barrel vascularised fibula
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Fibula / Surgery, Surgical Flaps
Novel Application of a Low-cost Alternative to Patient Specific Implants (PSI) in Mandibular Free Fibula Flap Reconstruction by Reverse Engineering of Stock Plates: A Pilot Validation Study
Stock reconstruction plates have been used for decades and represent a tried-and-true alternative to custom plating. Stock plates are readily available, are cost effective, and can be accurately bent before surgery, particularly…
- Conditions
- Fibula / Surgery, Surgical Flaps, Computer-Aided Design, Mandibular Reconstruction* / Methods
- Trial name
- NCT05672056
- Testing
- Computer guided placement of a stock plate pre-bent on a 3D printed model
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mandibular Neoplasms, Maxillary Neoplasms
3D-Printed Patient-Specific Surgical Plates Versus Conventional Surgical Plates in Jaw Reconstruction
Objectives: The aim of this randomised controlled clinical trial is to evaluate surgical accuracy and efficiency of computer-assisted jaw reconstruction using 3D-printed patient-specific titanium surgical plates versus…
- Conditions
- Mandibular Neoplasms, Maxillary Neoplasms, Dentofacial Deformities
- Trial name
- NCT04635865
- Testing
- 3D-printed patient-specific plate, Conventional commercial reconstruction plate
- Where
- Hong Kong
- Volunteers
- 92 people
- Sponsor
- The University of Hong Kong
Alveolar Bone Loss, Atrophy
Buccal Fat Pad Derived Stem Cells With Cortical Tenting in Posterior Mandible Reconstruction
In this study the buccal fat pad derived stem cells (BFPSCs) is harvested from buccal fat pad tissue of the patients receiving posterior mandible augmentation.
- Trial name
- NCT02745366
- Testing
- BFPSC+FDBA+PRF, FDBA+PRF
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences