Clinical trials: Marijuana Use
Cannabis-Related Disorder, Cannabis Abuse
Implementing Screening for Cannabis and Other Drug Use Disorders in Primary Care: Impact on Diagnosis and Treatment
Our proposed evaluation study is designed to evaluate the impact of a recently completed stepped wedge cluster randomized trial, conducted at Kaiser Permanente Washington (KPWA), of an intervention to improve care and management…
- Conditions
- Cannabis-Related Disorder, Cannabis Abuse, Drug Abuse, Drug Use Disorders
- Trial name
- NCT06249542
- Testing
- Care Delivery Improvement Intervention
- Volunteers
- 363,936 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Cannabis Use, Tobacco Use
Effect of Cannabis on E-Cigarette Use Behavior
The purpose of this study is to determine the impact of tetrahydrocannabinol (THC) administration on motivational, subjective, and physiological effects of electronic cigarettes.
- Conditions
- Cannabis Use, Tobacco Use, Electronic Cigarette Use
- Trial name
- NCT06609109
- Testing
- THC High Dose, THC Low Dose, THC 0mg
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Chronic Pain
Marijuana Use, Strength Training, and Alcohol Consumption (MUSTAC) Study
Self-medication of pain by consuming alcohol and marijuana is common. However, the research regarding pain as a determinant for alcohol and marijuana use has relied on laboratory pain induction paradigms with limited clinical…
- Trial name
- NCT04791917
- Testing
- Eccentric Biceps Flexion, Concentric Biceps Flexion
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Florida
Cannabis Use, Depression
Neural and Psychiatric Consequences of Cannabis Use in Adolescents
The goal of this study is to investigate the effects of cannabis on brain function among adolescents with depression.
- Trial name
- Cann-Teen (NCT06941298)
- Testing
- Neuroimaging Investigation
- Where
- 2 sites in United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Miami
Recreational Cannabis Use
Emotional Brain Processes in Recreational Cannabis Users
This fMRI study investigates neural correlates of emotion regulation, emotion processing and craving in recreational cannabis users.
- Trial name
- NCT02801214
- Testing
- fMRI
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Cannabis Use, Sleep
Cannabis Effects on Sleep, Circadian Rhythms, and Light Sensitivity in Young Adults
The goal of this study is to learn how cannabis use and discontinuation affect sleep, circadian rhythms, and sensitivity to light. The main questions it aims to answer are: 1.
- Conditions
- Cannabis Use, Sleep, Circadian Rhythm
- Trial name
- CASCILS (NCT06743373)
- Testing
- Cannabis Discontinuation
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cannabinoid, Discrepancy With Clinical Examination
Perioperative Prospective Follow Up Of Cannabis Consumers and Discrepancy Use
This study includes a prospective non interventional study that aims to asses the prevalence of cannabis use among patients undergoing elective surgery and evaluates its impact on perioperative outcomes, including pain, opioid…
- Trial name
- NCT07582445
- Testing
- This study is non interventional and will only include filling in questionnaires and providing blood and urine sample
- Where
- Israel
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Cannabis Use, Tobacco Use
Effect of Cannabis on Cigarette Use Behavior
The purpose of this study is to determine the impact of tetrahydrocannabinol (THC) administration on motivational, subjective, and physiological effects of cigarettes.
- Conditions
- Cannabis Use, Tobacco Use, Cigarette Smoking
- Trial name
- NCT06609083
- Testing
- THC 30mg, THC 5mg, THC 0mg
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cannabis Use, Tobacco Use
Influence of Tobacco Use on Cannabis Use
Cannabis smokers who also smoke tobacco cigarettes have markedly higher rates of cannabis relapse relative to those who do not use tobacco.
- Trial name
- NCT03766971
- Testing
- 7 days of Tobacco Cessation, 21 days of Tobacco Cessation, Cannabis
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Cannabis Use
Acute Effects of Cannabis on Cognition and Affect
This study will examine how a moderate dose of THC affects mood and cognitive functioning in regular cannabis users. The study uses a double-blind, placebo-controlled, crossover design, meaning each participant will complete two…
- Trial name
- NCT07296874
- Testing
- THC 20mg
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Washington State University
Microbiome Analysis, Drug Abuse in Pregnancy
Alcohol and Cannabis Use Among Pregnant Slovenian Women
The aim of the study is to determine the prevalence of alcohol and drug use among Slovenian pregnant women. Alcohol and drug use during pregnancy has significant effects on the foetus and has short- and long-term health…
- Conditions
- Microbiome Analysis, Drug Abuse in Pregnancy, Alcohol Abuse in Pregnancy, Health Behavior, Risky
- Trial name
- NCT07456579
- Where
- Slovenia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Cannabis Use
Effect of Cannabidiol (CBD) on Vision and Driving
The use of cannabis with ∆9-tetrahydrocannabinol (THC) content has been shown to have negative effects on vision and driving. The use of other cannabinoids, such as cannabidiol (CBD), which is not attributed with a psychoactive…
- Trial name
- NCT06322303
- Testing
- CBD 15%, CBD 30%
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Driving Under the Influence, Marijuana Intoxication
Cannabis Impairment Detection Application (CIDA)
Subjects will participate in a 4-visit study protocol in which they will be asked to complete a set of computerized tasks and a 45-minute simulated drive in a driving simulator.
- Conditions
- Driving Under the Influence, Marijuana Intoxication, Alcohol Intoxication
- Trial name
- CIDA (NCT04230460)
- Testing
- Cannabis (High% THC) (Inhaled), Cannabis (Very High% THC) (Inhaled), Alcohol (oral)
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Advanced Brain Monitoring, Inc.
Smoking
Development of a Videogame Prototype Targeting Cigarette and Marijuana Smoking, and Tobacco Product Prevention Among Young Adolescents (smokeScreen)
The goal of this sub-study is to learn more about how an educational videogame can feasibly be implemented and disseminated in youth programs.
- Trial name
- NCT03722888
- Testing
- smokeSCREEN video game
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yale University
Vaping, Adolescent
Nicotine and Cannabis Vape Labeling Experiment - Spring 2025
This study assesses how the ways in which nicotine and cannabis vaping devices are labeled impact use susceptibility, anticipated effects, and health harm.
- Conditions
- Vaping, Adolescent, Electronic Cigarette Use, Nicotine
- Trial name
- EPIC/ADVANCE (NCT06919276)
- Testing
- Vaping Device Labeling
- Where
- United States
- Volunteers
- 3,048 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Adolescent Problem Behavior, Truancy; Unsocialized
Substance Use Interventions for Truant Adolescents
This study evaluates a brief motivation-building intervention for parents and teens to reduce truancy and substance use. It is hypothesized that the motivational intervention will result in better outcomes compared to an…
- Conditions
- Adolescent Problem Behavior, Truancy; Unsocialized, Marijuana Abuse, Truancy; Socialized
- Trial name
- GOALS (NCT03655574)
- Testing
- Motivational + Family Check-up (MET+FCU), Psychoeducation
- Where
- 2 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Brown University
Cannabis Use, Stress
Perceptual Influences From Smoking Cannabis: an Experimental Study
The purpose of the study is to better understand the effects of cannabis in relation to mental and physical states including its relationship with mood, cognition, perception including the experience of temperature and pain, and…
- Trial name
- PISCES (NCT06588582)
- Testing
- Water Temperature Variation - WW, Water Temperature Variation - CW
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Cannabis Use
Investigating Cannabis Use Parameters on Anesthesia and Inflammation in Lumbar Spinal Surgeries
Cannabis is the most commonly used illicit drug in the United States with reported rates of use increasing from approximately 50 million in 2020 to 61.8 million in 2023 among individuals aged 12 or older.
- Trial name
- NCT07354412
- Where
- 2 sites in United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Alcohol Use, Cannabis Use
MATAspire: Mental Health Awareness Tailored App for Substance Prevention and Integrated Resilience Education
The MATAspire intervention is a web-app designed to promote substance misuse prevention education and bolster protective coping skills whereby students complete six weekly interactive modules using a smart device or computer.
- Conditions
- Alcohol Use, Cannabis Use, Nicotine Use, Illicit Drug Use
- Trial name
- MATAspire (NCT06553196)
- Testing
- MATAspire Web-app
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- California State University, Northridge
Concussion, Mild
The Combined Effect of Chronic Cannabis Use and Subconcussive Head Impacts on Brain Health
The purpose of this pilot study is to better understand the effects of chronic cannabis (THC) use on the neural responses to subconcussive head impacts, as a form of repetitive soccer headings.
- Trial name
- NCT04641832
- Testing
- Soccer heading
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Indiana University