Clinical trials: Mask
Anxiety, Anxiety After Surgery
The Study Evaluates the Effect of an Interactive Projector as a Distraction for Children During Anesthetic Induction. The Primary Objective is to Reduce Perioperative Anxiety, Measured With the Modified Yale Preoperative Anxiety Scale (mYPAS).
This study is designed to evaluate the effect of technology as a distraction technique during anesthetic induction in children, starting from their arrival to the operating room.
- Conditions
- Anxiety, Anxiety After Surgery, Induction of Anesthesia, Anxiety Preoperative
- Trial name
- NCT07230743
- Testing
- Custom projector-based video game intervention (BERT; Stanford Chariot Program, Palo Alto, CA), Standard Parent-Present Induction (PPI)
- Where
- Chile
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Clinica Alemana de Santiago
Abdominal Surgery
The Effect of Eye Mask and Music on Sleep Quality and Delirium in Patients Monitored in Intensive Care Unit
After abdominal surgery, most patients experience problems such as respiratory complications, surgical wound infection, cardiac problems, renal failure, delirium, and insomnia, along with surgical trauma and underlying…
- Trial name
- NCT06268158
- Testing
- Eye patch
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Dry Eye Disease
Study to Assess Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of Palovarotene Ophthalmic Solution in Healthy Adult Subjects
Dry eye disease (DED) is a keratoconjunctive disorder that "is a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort, visual disturbance, and tear film instability with potential damage…
- Trial name
- NCT04762355
- Testing
- Palovarotene, Vehicle
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Clementia Pharmaceuticals Inc.
Visual Stress, Meares-Irlen Syndrome
Reading; Through the Eyes of a University Student
This is a double-masked randomized controlled trial which aims to assess the effects of precision tinted spectacle lenses on visual stress symptoms within an undergraduate University student population.
- Conditions
- Visual Stress, Meares-Irlen Syndrome, Reading Difficulties
- Trial name
- NCT04318106
- Testing
- Precision tinted spectacle lenses
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Neonatal Complication, Neonatal Asphyxia
Face Mask vs Laryngeal Mask in Neonatal Resuscitation
The goal of this single-centre interventional study without medication neither device (for procedure) is to improve training of health care personnel (physicians, nurses, and midwives) on neonatal resuscitation through manikin…
- Trial name
- ManiMask2025 (NCT06952088)
- Testing
- Training on Neonatal Resuscitation
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Face, Newborn
Fitting of Commonly Available Face Masks for Late Preterm and Term Infants
Around ten percent of newborn infants require positive pressure ventilation (PPV) in the delivery room. This is most commonly delivered using a round or anatomically shaped face mask attached to a T-piece device, self-inflating…
- Conditions
- Face, Newborn, Preterm Infant
- Trial name
- CAFF (NCT03369028)
- Testing
- 2D and 3D image of infants´ faces
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Preoxygenation
Patient's Experience of Receiving Preoxygenation With the TTIM (Tube Tip in Mouth) Versus the Face Mask
Determining the subjective experience of receiving pre-oxygenation with either a face-mask or with the tip of the tube in the mouth (TTIM = TubeTipIn Mouth)
- Trial name
- TTIMvsMASK (NCT07914296)
- Testing
- Preoxygenation by Breathing via the tip of a tube hold in the mouth (= Tube Tip In the Mouth (TTIM), Preoxygenation via Face mask
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Difficult Intubation, Difficult Mask Ventilation
Ultrasound Predictors of Difficult Airway in Adults
Difficult airway management is a major cause of perioperative complications. Standard bedside airway assessment tests may have limited ability to predict difficult intubation and difficult mask ventilation.
- Conditions
- Difficult Intubation, Difficult Mask Ventilation, Difficult Airway
- Trial name
- NCT07383610
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Myopia
Myopia Control With Novel Eye Drops
Myopia currently affects 30% of the world and by 2050, almost 50% of the world will be myopic based on conservative estimates.1 In 2050, this will equate to almost 5 billion people with myopia, and those with high myopia will…
- Trial name
- NCT04301323
- Testing
- BHVI1 eye drops, BHVI2 eye drops, BHVI3 eye drops
- Where
- Vietnam
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Hai Yen Eye Care
Pre Operative Sedation, Mask Acceptance
Effect of Dexmedetomidine Versus Midazolam Versus a Combination of the Two as a Premedication for Children Undergoing Bilateral Myringotomy Tube Insertion
Following an obtained written consent, a child presenting for ear tube surgery will be randomized into one of three groups for receiving a premedication.
- Conditions
- Pre Operative Sedation, Mask Acceptance, Post Operative Delerium
- Trial name
- NCT02134327
- Testing
- Combination of Dexmedetomidine with Midazolam
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Healthy Volunteers
Study to Evaluate Safety, Tolerability & PK of rhNGF in Healthy Volunteers
The primary objective of this study is to assess the safety and tolerability of a single short-term and a multiple dose scheme of rhNGF when administered as eye drops in healthy subjects of Japanese ethnicity.
- Trial name
- NCT03836859
- Testing
- rhNGF 20μg/mL
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dompé Farmaceutici S.p.A
Apnea
Ventilation Using a Bag Valve Mask With Supplemental External Handle
Investigators compared tidal volumes for single rescuer ventilation using a modified bag valve mask with a supplemental external handle versus a conventional bag valve mask in a manikin model.
- Trial name
- NCT02800213
- Testing
- Modified Ambu Spur II bag valve mask, Conventional Ambu Spur II bag valve mask
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Healthy Volunteers
Efficacy, Safety and Tolerability Study of Chloroprocaine 3% Gel Eye Drops in Healthy Volunteers
The study assess efficacy, safety and tolerability of Chloroprocaine 3% ophthalmic gel in healthy volunteers.
- Trial name
- NCT04753710
- Testing
- Ocular gel
- Where
- Austria
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Sintetica SA
Anesthesia
Effects of One-handed and Two-handed Mask Ventilation Techniques on Global and Regional Lung Ventilation
Two-handed mask ventilation has been shown to provide higher tidal volume than one-handed mask ventilation. The effects of the two techniques on respiratory mechanics during induction of general anesthesia, however, still need to…
- Trial name
- NCT04617665
- Testing
- One-handed mask ventilation, Two-handed mask ventilation
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Fudan University
Allergic Conjunctivitis
Safety and Comfort of AL-4943A Ophthalmic Solution
The purpose of this study is to assess the ocular comfort and safety of olopatadine hydrochloride opthalmic solution. 0.7%.
- Trial name
- NCT01326858
- Testing
- Olopatadine hydrochloride ophthalmic solution, 0.7%, Olopatadine hydrochloride ophthalmic solution vehicle, Ketotifen fumarate ophthalmic solution, 0.025%
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Presbyopia
Safety and Efficacy Study BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic or Pseudophakic Presbyopia
Safety and Efficacy Study of BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic and Pseudophakic Presbyopia
- Trial name
- NCT05270863
- Testing
- BRIMOCHOL™ PF, Carbachol PF, Brimonidine tartrate
- Where
- 15 sites in United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Visus Therapeutics
Control Patients, Class III Malocclusion
Effect of Face Mask Therapy on Blood Oxygen Levels
Skeletal Class III malocclusions are characterized by maxillary retrusion, mandibular protrusion, or a combination of both. In growing individuals presenting with maxillary deficiency, the face mask appliance is widely recognized…
- Trial name
- NCT06939179
- Testing
- Class III Malocclusion
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Biruni University
Cataracts
Comparing Optical Coherence Tomography (OCT) and Visual Acuity Outcomes in Subjects Undergoing Cataract Surgery, Who Receive Xibrom Ophthalmic Solution and Standard Presurgical Care vs. Xibrom Ophthalmic Solution Plus Prednisolone Acetate 1% and Standard Presurgical Care
To compare the efficacy of twice-daily topical bromfenac (Xibrom) ophthalmic solution alone versus twice-daily topical Xibrom with prednisolone acetate 1% three-times daily on visual acuity and OCT measurements.
- Trial name
- NCT00698724
- Testing
- Xibrom, and Optive, Xibrom and Pred Forte
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bp Consulting, Inc
Contraception, Prevention of Sexually Transmitted Infections
Evaluation of Polyurethane Male Condoms
The clinical study will compare two lubricated polyurethane male condoms of different thickness with a marketed lubricated control male condom made of natural rubber latex.
- Trial name
- NCT04622306
- Testing
- Control Latex Condom C, Polyurethane Condom A, Polyurethane Condom B
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sagami Rubber Industries Co., Ltd.
Laryngeal Mask Airways, Fiberoptic Bronchoscopy (FOB)
Fiberoptic Evaluation of i-Gel and Air-Q sp3G Supraglottic Airway Devices in Pediatric Patients
This single-center, prospective, randomized controlled study aims to compare the placement accuracy of iGel and Air-Q sp3G supraglottic airway (SGA) devices in pediatric patients aged 1-8 years undergoing elective surgery under…
- Conditions
- Laryngeal Mask Airways, Fiberoptic Bronchoscopy (FOB), Elective Surgeries, Gastric Insufflation
- Trial name
- NCT07141498
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent