Clinical trials: Maximal Oxygen Uptake
Cardiorespiratory Fitness
Sprint Snacks: The Effects of Prolonged Rest on Reduced Exertion Interval Training.
An adapted sprint interval training protocol involving 2-3 repeated 20-second sprints separated by 2-3 minutes rest (termed reduced exertion high- intensity interval training (REHIIT)) has been developed and has been shown to…
- Trial name
- NCT03159949
- Testing
- REHIIT, PR-REHIIT
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Sedentary Behaviors, Physical Inactivity
Step-Up vs. Running Exercise at Matched Heart Rate Zones in Sedentary Males
This study compares the effects of two aerobic exercise methods - loaded step-up exercise and treadmill running - on cardiovascular fitness, leg strength, heart rate variability, and recovery in sedentary adult males.
- Trial name
- NCT07585617
- Testing
- Loaded Step-Up Exercise, Treadmill Running
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ankara University
Assessmet of VO2max in Elderly
Estimation of VO2Max Using Smartphone Application
The aim of this observational study Is to examine the validity of the Smartphone application (VO2max calculator) in calculating VO2max in elderly population.
- Trial name
- NCT06575608
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cardiopulmonary Exercise Test, End-Tidal Carbon Dioxide
Test-Retest Reliability And Validation For End-Tidal Carbon Dioxide Measurement (PetCO2) During Rest And Low-Loaded Steady State Work Using A Portable Capnograph.
The goal of this observational study is to investigate exhaled carbon dioxide measuring during rest and low-loaded work using a portable device (capnograph) and standard of care apparatus during a cardiopulmonary exercise test…
- Conditions
- Cardiopulmonary Exercise Test, End-Tidal Carbon Dioxide, VO2max, Ventilatory Physiology
- Trial name
- NCT07326449
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Linkoeping University
COPD
Maximal Oxygen Uptake (VO2max) in Patients With COPD
Patients with chronic obstructive pulmonary disease (COPD), facing a decline in lung function and compromised quality of life, often benefit from regular exercise (1).
- Trial name
- COPD-MAX (NCT06257381)
- Testing
- VO2max
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cystic Fibrosis in Children
Cardiopulmonary Fitness in Children With Cystic Fibrosis Compared to Healthy Children
Cystic fibrosis is the most common severe genetic disease with autosomal recessive transmission in the Caucasian population. Its prognosis has improved considerably since the creation of Cystic Fibrosis centers (CF centers) and…
- Trial name
- VOmuco (NCT06242951)
- Testing
- VO2 max assessment
- Where
- France
- Volunteers
- 345 people
- Sponsor
- University Hospital, Montpellier
Acute Coronary Syndrome, Arrhythmia
High-intensity Interval Training in Patients With Post-acute Coronary Syndrome
To date, no studies have evaluated the safety or efficiency (improvement of maximal oxygen uptake [VO2peak]) of a high-intensity interval training (HIIT) program in post-acute coronary syndrome (post-ACS) patients.
- Trial name
- EXIT-IV (NCT03414996)
- Testing
- Exercise training
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Montreal Heart Institute
Cardio-Respiratory Failure
Evaluation of Modification in VO2 Max After Performing the "Physical Activity and Health Course (PAPS) 53" Program
Physical inactivity is the leading cause of preventable death in developed countries, ahead of smoking. It is responsible for 5.3 million (9%) of the 57 million deaths worldwide in 2008 and 10% of deaths in Europe.
- Trial name
- EVOP-53 (NCT05082324)
- Testing
- Adapted physical activity
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Angers
Exercise Test, Thoracic Cancer
Interest of CPET to Predict Mortality and Complications of Lung Resection Candidates
Anatomic lung resection is the treatment of choice for the management of cancerous lung nodules Non-Small-Cell Lung Carcinoma (NSCLC). Systematic functional evaluation can reduce the risk of mortality and morbidity of candidates.
- Trial name
- NCT05502263
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Université Libre de Bruxelles
Congestive Heart Failure
Testosterone Improves Exercise Oxygen Uptake, Insulin Resistance and Muscle Strength in Elderly Patients With Chronic Heart Failure
Background: Patients with congestive heart failure (CHF) show muscle mass wasting and decreased testosterone levels. Long-term testosterone supplementation improves walking distance and glucose metabolism of patients CHF.
- Trial name
- NCT00512408
- Testing
- testosterone
- Where
- Italy
- Sponsor
- IRCCS San Raffaele
Type 1 Diabetes
Impact of Eccentric Training in Hypoxia With Creatine on Metabolic Control and VO2max in Patients With Type 1 Diabetes
Exercise plays an important role in treatment of diabetes. In recent years exercise training in normobaric hypoxia is used in training programs for athletes and in rehabilitation and also commercially.
- Trial name
- NCT06345612
- Testing
- hypoxia, normoxia, creatine supplementation
- Where
- Poland
- Volunteers
- 28 people
- Sponsor
- Silesian Centre for Heart Diseases
Athletic Performance, Aerobic Capacity
Individualized Training to Improve Aerobic Capacity and 2,000 m Rowing Performance in Youth Rowers
The goal of this randomized clinical trial is to learn whether an individualized rowing training program based on ventilatory thresholds can improve aerobic capacity and 2,000 m rowing performance in youth rowers from Valdivia…
- Conditions
- Athletic Performance, Aerobic Capacity, Rowing Performance
- Trial name
- NCT07602244
- Testing
- Individualized Rowing Training, Usual Rowing Training
- Where
- Chile
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universidad San Sebastián
Healthy Adults
Normative Data for Cardiorespiratory Fitness in Healthy Adults
Cardiorespiratory fitness (CRF) is a physical attribute which represents how effectively various bodily systems work together to transport and utilize oxygen to support muscular activity during prolonged, rhythmic, large-muscle…
- Trial name
- NDFCFIHAUTQCST (NCT07275619)
- Where
- Pakistan
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cardiovascular Fitness
Physiological and Perceptual Responses During 4-Second Exercise
The purpose of this study is to investigate the acute effects of different intensities (i.e., 50, 75, and 100% of maximal anaerobic power) of 4-s sprint interval exercise on physiological responses.
- Trial name
- NCT06912932
- Testing
- Preventive
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Ankylosing Spondylitis
Evaluation of Physical Performance in Ankylosing Spondylitis Patients
Ankylosing spondylitis (AS) can cause serious limitations in individuals' physical performance, as it involves the musculoskeletal system and can cause ankylosis and arthritis in both axial and peripheral joints.
- Trial name
- NCT04451681
- Testing
- Cardiopulmonary exercise test
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Physical Fitness
Endurance Exercise on nrf2 mRNA Expression Gene and VO2max
Indonesian Hajj Health Officers have the responsibility and very important role in providing health services for Indonesian pilgrims during embarkation and debarkation.
- Trial name
- NCT04366479
- Testing
- Multistage Fitness Test
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Single Ventricle Heart Disease
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2
This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo for the treatment of adolescent who have had the Fontan procedure.
- Trial name
- FUEL-2 (NCT05918211)
- Testing
- Udenafil
- Where
- 40 sites in United States, South Korea
- Volunteers
- 436 people
- Sponsor
- Mezzion Pharma Co. Ltd
Lymphoblastic Leukemia, Cancer Survivors
Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors
This will be a randomized, placebo-controlled trial with a 2x2 factorial design testing the effects of an NAD+ precursor (NR) and exercise on skeletal muscle quality and VO2max in AYA HCT survivors.
- Conditions
- Lymphoblastic Leukemia, Cancer Survivors, Aplastic Anemia, Myelodysplastic Syndromes
- Trial name
- IAMFIT (NCT05194397)
- Testing
- Nicotinamide Riboside, Exercise Intervention
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Children's Hospital of Philadelphia
Diabete Type 1
Cardiopulmonary Fitness and Health-Related Quality of Life in Children and Adolescents With Type 1 Diabetes (FIT-T1D)
Children and adolescents with type 1 diabetes (T1D) are at risk of a sedentary lifestyle, as this chronic disease may lead patients into a vicious cycle of deconditioning, resulting in reduced physical activity levels and…
- Trial name
- FIT-T1D (NCT07728435)
- Where
- France
- Volunteers
- 214 people
- Sponsor
- Institut Saint Pierre
Pulmonary Disease, Chronic Obstructive, Hyperoxia
Effective High Aerobic Intensity Endurance Training Regimes in Chronic Obstructive Pulmonary Disease (COPD) Patients
4 times 4 minutes interval training with and without hyperoxia is more effective than low intensity endurance training.
- Trial name
- NCT00658853
- Testing
- 4 times 4 minutes high aerobic intensity one leg cycling
- Where
- Norway
- Volunteers
- 26 people
- Sponsor
- Norwegian University of Science and Technology