Clinical trials: Maximal Oxygen Uptake
Elite Cyclists, Elite Soccer Players
Exploring the Relationship Between the Gut Microbiome, Physical Fitness Levels and Metabolic Responses to Exercise
Gut microbiota are all microorganisms including bacteria and microscopic eukaryotes that live in the digestive tracts of humans or mammals.
- Conditions
- Elite Cyclists, Elite Soccer Players, Sedentary Behavior
- Trial name
- EXOMIC (NCT05220657)
- Testing
- Maximal incremental exercise test, Submaximal exercise test
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Athletic Performance, Aerobic Capacity
Individualized Training to Improve Aerobic Capacity and 2,000 m Rowing Performance in Youth Rowers
The goal of this randomized clinical trial is to learn whether an individualized rowing training program based on ventilatory thresholds can improve aerobic capacity and 2,000 m rowing performance in youth rowers from Valdivia…
- Conditions
- Athletic Performance, Aerobic Capacity, Rowing Performance
- Trial name
- NCT07602244
- Testing
- Individualized Rowing Training, Usual Rowing Training
- Where
- Chile
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universidad San Sebastián
Hypoxia
The Effect of Inhaled Nitric Oxide on Maximal Oxygen Consumption During Exercise in Hypoxia
During exercise in conditions of low oxygen (termed hypoxia), such as mountaineering at high altitudes, the lung blood vessels constrict in an attempt to protect the body from the negative effects of hypoxia.
- Trial name
- iNO (NCT04231773)
- Testing
- Nitric Oxide
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Healthy
VO2 Max: In Vivo Model for Functional Red Cell Testing. Can RECESS be Explained?
This is a single-center, randomized, partially blinded study to determine whether 42-day old red blood cells (RBCs) deliver oxygen as effectively as 7-day old RBCs and also to determine whether transfusion with 28-day old RBCs is…
- Trial name
- NCT02918851
- Testing
- Transfusion of 7-day stored red blood cells, Transfusion of 28-day stored red blood cells, Transfusion of 42-day stored red blood cells
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Aerobic Fitness (VO2max)
The Effects of Vitamin D Supplementation on Aerobic Fitness in Athletes
The primary aim of the study is to identify if vitamin D3 supplementation influences VO2max in athletes. Secondary aims are to determine if vitamin D3 supplementation impacts on measures of muscle function, lung function, body…
- Trial name
- VDAF (NCT02278172)
- Testing
- Vitamin D
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Hyperoxia / High FiO₂ Exposure, Interval Training
Oxygen as a Metabolic Modulator: Divergent Physiological Adaptations to Hypoxic and Hyperoxic Tabata Training.
The purpose of this study is to examine how breathing air with different oxygen concentrations (higher or lower than normal) during high-intensity interval training affects: Aerobic capacity (VO₂max) Ventilatory thresholds Blood…
- Conditions
- Hyperoxia / High FiO₂ Exposure, Interval Training, HIIT, High Intensity Interval Training
- Trial name
- NCT07551869
- Testing
- FIO2 modulation during HIIT protocol on assault bike
- Where
- Belgium
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Haute Ecole Bruxelles-Brabant
Single Ventricle Heart Disease
Fontan Udenafil Exercise Longitudinal Assessment Trial
This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo for the treatment of adolescent subjects who have undergone the Fontan…
- Trial name
- FUEL (NCT02741115)
- Testing
- Udenafil
- Where
- 30 sites in United States, Canada and 1 more
- Volunteers
- 400 people
- Sponsor
- Mezzion Pharma Co. Ltd
Ramadan Fasting
Impact of Dietary Nitrate Supplementation on VO2max During Ramadan Fasting in Healthy Adults
The goal of this clinical trial is to determine if beetroot juice supplementation changes exercise performance following one week of Ramadan fasting in young, healthy adults.
- Trial name
- NCT06767176
- Testing
- Beetroot Juice (Beet-It Stamina Shot) & Supervised Exercise Training
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University of Guelph
Educational Control, Resistance Training
High Speed Circuit Training and Cognition
The purpose of this research study is to see if a weight training program can make a positive change in participant fitness as measured by the ability to use oxygen and help the participant remember things.
- Trial name
- NCT04022707
- Testing
- High-speed circuit resistance training, Educational control
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cardiomyopathies, Truncation Mutation
Moderate Intensity Training in Patients With Truncating Genetic Variants in TTN.
The aim is to investigate the effect of an 8-week moderate-intensity exercise program on aerobic fitness and cardiac contractility in patients with truncations of the sarcomeric protein titin.
- Conditions
- Cardiomyopathies, Truncation Mutation, TTN
- Trial name
- NCT05180188
- Testing
- Training
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Aging, Healthy
High-intensity Training for Improving Physical Performance of Aged Women
This study evaluates the adaptations on the functional capacity and cardiovascular in elderly after a physical activity program circuit training.
- Conditions
- Aging, Healthy, Cardiovascular Risk Factor, Physical Activity
- Trial name
- AHIITATE (NCT03840330)
- Testing
- Experimental: High-intensity interval training group, Experimental: Moderate-intensity interval training group
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
Lymphoblastic Leukemia, Cancer Survivors
Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors
This will be a randomized, placebo-controlled trial with a 2x2 factorial design testing the effects of an NAD+ precursor (NR) and exercise on skeletal muscle quality and VO2max in AYA HCT survivors.
- Conditions
- Lymphoblastic Leukemia, Cancer Survivors, Aplastic Anemia, Myelodysplastic Syndromes
- Trial name
- IAMFIT (NCT05194397)
- Testing
- Nicotinamide Riboside, Exercise Intervention
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Children's Hospital of Philadelphia
Respiratory Muscle Training, Inspiratory Muscle Strength
The Effects of Interval Respiratory Muscle Training on Athletic Performance
This study evaluated the effects of a 4-week respiratory muscle training (RMT) program using constant versus incremental threshold resistance on respiratory muscle strength, pulmonary function, extremity strength, and…
- Conditions
- Respiratory Muscle Training, Inspiratory Muscle Strength, Maximal Oxygen Consumption
- Trial name
- NCT07887282
- Testing
- IMT %40 MIP, IMT %50-60-70-80
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Physical Activity
Effects of WB-EMS in Runners.
The subjects will be randomly distributed into 3 experimental groups: training with basic global electrostimulation (WB-EMS-SRT), training with specific global electrostimulation for runners (WB-EMS-WT) and control group (CG).
- Trial name
- NCT03425981
- Testing
- Whole-Body Electromyostimulation Training
- Where
- Spain
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Ineffective Erythropoiesis
Echinacea-based Supplement Does Not Improve Markers of Performance in Athletes
The purpose of this study was three-fold. We wanted to (1) determine if supplementation with an echinacea-based dietary supplement (ECH) would increase several blood parameters that could affect oxygen carrying capacity in the…
- Trial name
- NCT02134119
- Testing
- Echinacea-based dietary supplement
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Improved VO2max and Cardiac Output in Response to Training
Effect of Ethnicity on Changes in VO2max and Cardiac Output in Response to Short-Term High Intensity Interval Training
The purpose of this study was to determine if ethnicity alters training responsiveness to a low dose of high intensity interval training in inactive women.
- Trial name
- NCT04449016
- Testing
- High intensity interval training
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- California State University, San Marcos
Oxygen Consumption
Assessment of Maximal Oxygen Uptake in Cardiac Rehabilitation
To advance the methodology for evaluating persons with heart disease and their maximal oxygen uptake, the primary aim of this study is to investigate the occurrence of a plateau in oxygen uptake.
- Trial name
- NCT06113133
- Testing
- measurement of oxygen uptake
- Where
- Denmark
- Volunteers
- 97 people
- Sponsor
- VIA University College
Cardiopulmonary Exercise Test
Validity of SeismoFit VO2max Estimation in Patients With Heart Failure or Ischemic Heart Disease
Measurement of cardiorespiratory fitness (VO2max) is considered an important tool in risk prediction of cardiovascular disease and overall patient management.
- Trial name
- NCT05520307
- Where
- Denmark
- Volunteers
- 180 people
- Sponsor
- University of Copenhagen
Acute Myocardial Infarction
Effects of Cardiac Rehabilitation on High Mobility Group Box-1 Levels After Acute Myocardial Infarction
This purpose of this study is to examine the relationship between HMGB-1 and postinfarction predictors of outcome such as cardiopulmonary and echocardiographic parameters before and after a 6-month exercise-based cardiac…
- Trial name
- NCT00755131
- Testing
- Exercise-based Cardiac Rehabilitation program
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- Federico II University
Heart Failure
The Effect of Omega-3 Polyunsaturated Fatty Acids in Congestive Heart Failure
A diet rich in Omega-3 (fish oil) reduces plasma triglycerides and the risk for ischemic heart disease. Recently, a large trial evaluating treatment with Omega 3 in heart failure patients suggested that omega 3 may lower the risk…
- Trial name
- NCT00944229
- Testing
- LOVAZA (Omega-3)
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Columbia University