Clinical trials: Medical Informatics
Emergency Medicine, Artificial Intelligence (AI)
Diagnostic Accuracy of GPT-4o and Claude for HEART Score Calculation in Chest Pain
This prospective observational diagnostic accuracy study evaluates whether large language models (LLMs) - GPT-4o (OpenAI, gpt-4o-2024-11-20) and Claude (Anthropic, claude-sonnet-4-6) - can accurately calculate HEART scores from…
- Conditions
- Emergency Medicine, Artificial Intelligence (AI), Artificial Intelligence (AI) in Diagnosis, Chest Pain Rule Out Myocardial Infarction
- Trial name
- LLM-HEART (NCT07626060)
- Testing
- GPT-4o HEART Score Calculator, Claude HEART Score Calculator, Three-Expert Consensus HEART Score
- Where
- Turkey (Türkiye)
- Volunteers
- 690 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Asthma, Medical Informatics
A Reminder System for Paper-Based Asthma Guidelines in the Pediatric Emergency Department
The primary idea is that the use of a computerized reminder system to help with the guideline implementation will increase utilization and adherence of guideline-driven care, leading to improved patient outcomes.
- Trial name
- NCT00699439
- Testing
- Paper-based asthma flow diagram
- Where
- United States
- Volunteers
- 1,102 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Breast Cancer, Colorectal Cancer
Population-Based Patient-Centric Care: Comprehensive Preventive Cancer Screening Using Health IT
Although there is considerable evidence that current health IT can improve certain elements of care, the most effective and efficient implementation of health IT systems for primary care population management are not currently…
- Conditions
- Breast Cancer, Colorectal Cancer, Cervical Cancer
- Trial name
- TopCare (NCT01372527)
- Testing
- TopCare: Use of provider knowledge vs. automated system
- Where
- United States
- Volunteers
- 103,870 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Colon Cancer, Breast Cancer
Understanding the Value of Community Vital Signs in Primary Care
Social determinants of health (e.g. the income, education, and environment of patients) may exert greater influence on health outcomes than traditional clinical factors (e.g. lab results, diagnoses, and family history).
- Conditions
- Colon Cancer, Breast Cancer, Cervical Cancer, Prostate Cancer
- Trial name
- NCT02512835
- Testing
- Community vital signs
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Hypertension
VISN Collaborative for Improving Hypertension Management With ATHENA-HTN
This project is a VA HSR\&D-funded Quality Enhancement Research Initiative (QUERI) project to translate into practice evidence about clinical management of primary hypertension.
- Trial name
- HTN (NCT00374452)
- Testing
- ATHENA-CDS-HTN plus Guideline Link, Guideline Link Only
- Where
- 7 sites in United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Community-associated Infections, Health-care Acquired Infections
Optimal Antibiotic Treatment of Moderate to Severe Bacterial Infections
Severe bacterial infections are associated with mortality of about 30%. Patients with moderate to severe bacterial infections given early and appropriate empirical antibiotic treatment are at a lesser risk for a fatal outcome…
- Conditions
- Community-associated Infections, Health-care Acquired Infections, Nosocomial Infections
- Trial name
- CDSS (NCT01338116)
- Testing
- antibiotic treatment of by TREAT/PCR
- Where
- Israel
- Volunteers
- 600 people
- Sponsor
- Rabin Medical Center
Breast Neoplasms, Medication Adherence
A Novel E-Health Approach in Optimizing Treatment for Seniors (OPTIMUM Study)
Background: In women with hormone receptor positive (HR+) breast cancer, adjuvant endocrine therapy (AET) is associated with a significant survival advantage.
- Trial name
- NCT02876848
- Testing
- OPTIMUM e-health tool
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Schizophrenia, Chronic Illness
Implementing Effective, Collaborative Care for Schizophrenia (EQUIP-2)
This project evaluates the implementation and effectiveness of a care model to improve treatment for schizophrenia within the context of diverse VA practices and priorities.
- Conditions
- Schizophrenia, Chronic Illness, Weight Gain, Psychotic Disorder
- Trial name
- EQUIP-2 (NCT00137280)
- Testing
- Collaborative Chronic Illness Care Model
- Where
- 8 sites in United States
- Volunteers
- 1,067 people
- Sponsor
- VA Office of Research and Development
General Surgery, Oncology
3D Modeling for Detecting Locally Advanced Rectal Cancer With Positive Circumferential Resection Margin
This retrospective study aims to develop an AI-assisted 3D modeling system to improve staging accuracy for stage II-III locally advanced rectal cancer (LARC).
- Conditions
- General Surgery, Oncology, Medical Informatics
- Trial name
- NCT07183124
- Testing
- AI-Assisted 3D Imaging Model for Tumor and CRM Assessmen
- Where
- Taiwan
- Volunteers
- 1,500 people
- Sponsor
- Taichung Veterans General Hospital
Breast Neoplasms, Prostatic Neoplasms
Investigating the Impact of Tailored Reports on Anxiety Amongst Cancer Patients and Their Confidants
Objective: To explore the hypothesis that different methods of selecting and printing information for cancer patients could improve emotional support by affecting interaction with others, and so lead to improved psychological…
- Conditions
- Breast Neoplasms, Prostatic Neoplasms, Laryngeal Neoplasms, Cervix Neoplasms
- Trial name
- NCT00127465
- Testing
- Issue of information booklet
- Where
- United Kingdom
- Volunteers
- 400 people
- Sponsor
- University of Plymouth
Patient Transfer to Intensive Care Unit (Procedure), Respiratory Arrest (Disorder)
Evaluation of the Patient Deterioration Warning System
The overall goal of the project is to reduce the number of unexpected patient deteriorations by 50% at Emergency Departments (ED) by investigating if the novel Patient Deterioration Warning Systems (PDWS), can improve clinicians'…
- Conditions
- Patient Transfer to Intensive Care Unit (Procedure), Respiratory Arrest (Disorder), Cardiac Arrest (Disorder), Patient Died in Hospital (Finding)
- Trial name
- PDWS (NCT03375658)
- Testing
- PDWS Intervension
- Where
- 2 sites in Denmark
- Volunteers
- 6,500 people
- Sponsor
- University of Southern Denmark
Troponin, Age
NIHR CV Health Informatics Collaborative
The National Institute for Health Research (NIHR) Cardiovascular Health Informatics Collaborative is an observational, multi-centre and longitudinal study of clinical data from collaborating hospitals.
- Conditions
- Troponin, Age, Mortality, Acute Coronary Syndrome
- Trial name
- NHIC-CV (NCT03507309)
- Volunteers
- 257,948 people
- Sponsor
- Imperial College London
Lung Neoplasms
Development and Pilot Testing of a Clinical Informatics Lung Cancer Screening Intervention
This study evaluates the feasibility of a clinical informatics system-based approach to lung cancer screening. Patients of a large academic medical center who may qualify for lung cancer screening will be sent an electronic…
- Trial name
- NCT02962115
- Testing
- Decision Aid Invitation
- Volunteers
- 1,000 people
- Sponsor
- Wake Forest University Health Sciences
Health Disparity, Minority and Vulnerable Populations
Pilot Test of a Mobile App That Helps Spanish-speakers Find Mental Health Services in the US.
The goal of this observational study is to develop and test a mobile app for Spanish speakers residing in the US who seeking drug treatment and/or behavioral health services for themselves or an associate.
- Trial name
- NCT06619431
- Testing
- Mobile Application
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Volver Health
Obesity
Reporting Patient Generated Health Data and Patient Reported Outcomes With Health Information Technology
This study will assess the feasibility of using patient-centered, commercial off-the-shelf (COTS) health information technology (IT) solutions to collect patient generated health data (PGHD) and patient-reported outcomes (PROs)…
- Trial name
- NCT03386773
- Testing
- 16-week program, Patient generated health data
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Denver Health and Hospital Authority
Medical Informatics, Pediatric Emergency Medicine
Mobile Chat Service for Parents of Children in Pediatric Emergency Room
The goal of this clinical trial is to test giving all medical/non-medical information in the pediatric emergency room(ER). Main questions it aims to answer are: Does providing medical/non-medical information to parents of…
- Conditions
- Medical Informatics, Pediatric Emergency Medicine, Emergency Medicine
- Trial name
- NCT06002542
- Testing
- Information provided, Control
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Diabetes Mellitus
Impact of an Interprofessional Shared Decision-making and Goal-setting Decision Aid for Patients With Diabetes
Diabetes care is complicated for people with diabetes as well as for health care providers: they have to watch their diet, exercise, take medications, checking blood sugars and blood pressure, get tests and see multiple doctors.
- Trial name
- NCT02379078
- Testing
- Shared decision-making aid, Generic hard copy diabetes resources, Generic online diabetes resources
- Volunteers
- 225 people
- Sponsor
- Unity Health Toronto
Neoplasms, Communication
My Team of Care: a Pilot Randomized Controlled Trial of an Online Communication Tool for Collaborative Care
This project will pilot and test a new online communication tool, Loop, developed within a research framework with participatory and user-centred design. This pilot trial focuses on advanced cancer as an example of complex care.
- Trial name
- Loop (NCT02372994)
- Testing
- Loop
- Where
- 2 sites in Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Pulmonary Embolism
Nudging Provider Adoption of Clinical Decision Support
The central hypothesis of this proposal is that the addition of a theory-informed "nudge" to a clinical decision support (CDS) tool will address identified behavioral barriers to use and significantly improve adoption by…
- Trial name
- NCT05203185
- Testing
- Pulmonary Embolism Risk Kalculator (PERK)
- Where
- 2 sites in United States
- Volunteers
- 1,612 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Medical Informatics, Intensive Care
Patient Monitoring in the Intensive Care Unit
a cross-sectional survey of nurses' perception of patient monitoring in the ICUs
- Trial name
- NCT05847803
- Testing
- No intervention, questionnaire survey
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine