Clinical trials: Memory Consolidation
Depression
Does Depression Impact Our Memory for Rewarding Experiences
When individuals experience depression, they may find that their brain does not work in the same way that they are used to. For example, sometimes the ability to remember things that happened during the day is not so good.
- Trial name
- NCT05276583
- Testing
- Motivated Learning Task
- Where
- Germany
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Sleep, Memory
Hypnotic Medications and Memory: Effect of Drug Exposure During the Night
The purpose of this study is to determine the effect of two hypnotic medications, zolpidem extended release and zaleplon, on memory.
- Trial name
- NCT01159652
- Testing
- zaleplon, zolpidem extended release
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Chesterfield, Missouri
Healthy Aging
The Effect of Training on Brain Activity During Postural Tasks in Older Adults
Older people show deficits in dynamic weight-shifting, as the investigators found that more time is needed to perform weight-shifts and the movements became less fluent and accurate in older versus younger adults.
- Trial name
- NCT04594148
- Testing
- Weight-shift training
- Where
- Belgium
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- KU Leuven
HIV/AIDS
Translation of Basic Research in Cognitive Science to HIV Risk
A randomized trial was conducted at drug diversion educational programs with a sample of 343 adult drug offenders who volunteered for the study.
- Trial name
- NCT03175250
- Testing
- Health Education, Action Plan, Memory Practice
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- Claremont Graduate University
Sleep Disorder
Safety and Performance Study of the Electroencephalographic Recording Device and Sound Emissions
Safety and performance study of the MemoWave electroencephalographic and sound recording device to increase slow brain waves during sleep to improve memory consolidation in subjects with mild cognitive impairment
- Trial name
- MEMOWAVE (NCT04875442)
- Testing
- Memowave emitting sounds, Memowave not emitting sounds
- Where
- France
- Sponsor
- BioSerenity
Language Development Disorders
Perceptual Learning and Memory Consolidation in Adults With and Without LI
This study tests a memory-based account of atypical speech perception in adults with language-based learning disability (also known as developmental language impairment [LI]).
- Trial name
- NCT03609502
- Testing
- behavioral training
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Intrusive Memories
Behavioral Modulation of Intrusive Memories
The purpose of the study is to examine whether sleep affects the development of intrusive memories.
- Trial name
- NCT03227081
- Testing
- Sleep Deprivation
- Where
- Germany
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Speech, Consolidation
Sensory Memory in Speech Motor Learning
The proposed studies focus on memory for speech movements and sounds and its relation to learning. Continuous theta-burst transcranial magnetic stimulation (cTBS) will be used to suppress activity in a region of pre-frontal…
- Trial name
- NCT04818268
- Testing
- Adaptation, cTBS
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yale University
Epilepsy, Memory Consolidation
The Effect of Memory-Based Exercise and Planned Training Applied to Epilepsy Patients on Quality of Life
Epilepsy; It is a chronic, neurological disease that can occur regardless of social class, race and age. Every year, approximately 5 million people worldwide are diagnosed with epilepsy and 50 million people are affected by this…
- Conditions
- Epilepsy, Memory Consolidation, Education of Patients, Quality of Life (QOL)
- Trial name
- NCT06954922
- Testing
- memory-based exercise and training intervention, educational initiative about epilepsy
- Volunteers
- 50 people
- Sponsor
- Ataturk University
Elderly Subjects
Effects of Brain Stimulation During Nocturnal Sleep on Memory Consolidation in Elderly Healthy Subjects
The beneficial effect of nocturnal sleep on memory consolidation is well-documented in young, healthy subjects. Especially, periods rich in slow-wave sleep (SWS) have shown a memory enhancing effect on hippocampus-dependent…
- Trial name
- NCT01791790
- Testing
- Stimulation
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Mild Cognitive Impairment Due to Alzheimer's Disease, Subjective Cognitive Decline (SCD)
Autophagy-Enhancers to Reduce Sleep Disturbances
This clinical trial investigates the effects of spermidine supplementation on sleep quality and sleep-dependent memory consolidation in older adults with Subjective Cognitive Decline (SCD) or Mild Cognitive Impairment (MCI), two…
- Trial name
- SpSleep (NCT07383311)
- Testing
- Spermidine Supplementation
- Where
- Germany
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Epilepsy, Memory Consolidation
Sleep and Rehearsal-Driven Memory in Epilepsy
Memory consolidation transforms unstable memory traces into lasting representations, a process enhanced by both sleep and rehearsal during learning.
- Trial name
- CORESOM-EPI (NCT06967935)
- Testing
- Cognitive memory task on a computer, Eye tracking, Questionnaires on task-related fatigue
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Multiple Myeloma
Autologous Memory-like NK Cell Therapy With BHV-1100 and Low Dose IL-2 in Multiple Myeloma Patients
This is an open-label single center Phase 1a/1b study with the primary objective of establishing the safety and exploring the efficacy of infusing the ex vivo combination product of BHV-1100 plus cytokine induced memory-like…
- Trial name
- NCT04634435
- Testing
- BHV-1100 plus cytokine induced memory-like (CIML) NK cells plus IVIG and low dose IL-2
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Biohaven Pharmaceuticals, Inc.
Parkinson Disease, Aging
Role of Sleep on Motor Learning in Parkinson's Disease and Healthy Older Adults
People with Parkinson's disease (pwPD) often present difficulty consolidating newly learned skills into long-term memory. Sleep facilitates motor memory consolidation in healthy adults, especially in combination with targeted…
- Trial name
- TARGET-SLEEP (NCT04144283)
- Testing
- NAP, WAKE
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Schizophrenia and Related Disorders, Psychotic Disorders
Exercise and Overnight Motor Sequence Task
The objective of this randomized controlled trial (RCT) is to compare the changes of the sleep-related memory functions in patients with psychosis after they have completed the 12-week high-intensity exercise intervention, the…
- Trial name
- EOMST (NCT03800368)
- Testing
- Exercise, Non-exercise
- Volunteers
- 51 people
- Sponsor
- The University of Hong Kong