Clinical trials: Memory Functions
MCI, Aging
Studying the Effects of Digital Interventions on Cognition, Wellbeing, Stress, and Sleep in Older Adults
The goal of this proposed research is to collect pilot data to test the hypothesis that treatment with a novel form of closed-loop digital meditation (MediTrain) will lead to a greater magnitude of gains in cognitive abilities in…
- Trial name
- MediDream (NCT06633978)
- Testing
- MediTrain, wrist worn multi-sensor watches, Sleep monitor
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Schizophrenia, Schizoaffective Disorder
Database Registry for Neural Network Biomarkers in Psychosis
Several observations have been made with magnetic resonance imaging (MRI) that characterize brain connections and brain function in individuals with schizophrenia and other mental disorders.
- Trial name
- Imaging (NCT01409109)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Cognitive Function, Memory
The Memory and Cognitive Performance Study
The primary purpose of this study is to evaluate the impact of a novel, neuro-protective and neuro-restorative dietary supplement (Braini®) on standardized memory and cognitive performance parameters.
- Conditions
- Cognitive Function, Memory, Brain Health
- Trial name
- NCT04025255
- Testing
- Braini
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Vita Naturel, LLC
Cognitive Change
The Cognitive Effects of 6- and 12-weeks Administration of a Food Supplement Containing Phosphatidylserine in Healthy Children Aged 8 to 12 Years
The purpose of this study is to assess the cognitive effects (attention, learning, and memory) of 6 and 12 weeks administration of a supplement containing phosphatidylserine in comparison to a placebo in healthy children aged 8…
- Trial name
- NCT05177978
- Testing
- Phosphatidylserine
- Where
- United Kingdom
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Cognitive Function
Sensory Enrichment for Older Adults
This study evaluates the efficacy of multi-odorant enrichment on cognitive skills, olfactory function, and quality of life.
- Trial name
- NCT03914989
- Testing
- olfactory enrichment (essential oils)
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Aging
Older Age and Generalization
The goal of this clinical is to learn how the brain supports different kinds of memory decisions in healthy young and older adults.
- Trial name
- NCT07440017
- Testing
- Memory decision type
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Caitlin Bowman
Nicotine Dependence
Effects of Chantix on Relapse Prevention for Smoking Cessation
The goal of the proposed study is to validate an experimental paradigm to assess medication effects on smoking relapse following a brief (3-day) monitored period of smoking abstinence and a programmed cigarette lapse.
- Trial name
- NCT00948649
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Real HD-tDCS, Sham HD-tDCS
Determining the Specificity of High Definition Electrical Brain Stimulation Using Simultaneous Magnetoencephalography
Non-invasive human brain stimulation using weak transcranial direct-current stimulation (tDCS) has been thousands of times in research studies over the past fifteen years as a therapy to help improve the effectiveness of repeated…
- Conditions
- Real HD-tDCS, Sham HD-tDCS, Visual Task, Motor Task
- Trial name
- NCT02060708
- Testing
- HD-tDCS
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Alzheimer Disease, Alzheimer Disease, Late Onset
Effectiveness of Alzheimer's Universe (Www.AlzU.Org) on Knowledge and Behavior
To evaluate the effectiveness of an online educational course on Alzheimer's disease (AD) prevention, treatment and caregiving.
- Conditions
- Alzheimer Disease, Alzheimer Disease, Late Onset, Memory Loss, Patient Education as Topic
- Trial name
- NCT03149380
- Testing
- Web-based education
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Breast Cancer Survivors
A Study of Attention and Memory Processes in Breast Cancer Survivors
The purpose of this study is to observe the attention and memory processes in breast cancer survivors. Both cancer survivors and healthy volunteers (who are the same age as the cancer survivors) will participate in this study so…
- Trial name
- NCT04883398
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Memory Losses, Amnesia-Memory Loss
Effect of Affective Content on Drug Induced Amnesia of Episodic Memory
The purpose of this research is to understand how some of the drugs commonly used in anesthesia impair memory. We are particularly interested in whether the emotion associated with a memory influences how well these drugs are…
- Trial name
- NCT00142493
- Testing
- Propofol, Thiopental Sodium, Dexmedetomidine Hydrochloride
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Binge Drinking
Combining Cognitive Training With tDCS to Enhance Memory Inhibition in Young Binge Drinkers
This study protocol aims to examine the behavioral and electroencephalographic (EEG) correlates of memory inhibition (MI) among college binge drinkers (BDs).
- Trial name
- NCT05237414
- Testing
- Active tDCS, Active CT
- Where
- Portugal
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Minho
Aging
The Wandering Nerve: Gateway to Boost Alzheimer's Disease Related Cognitive Performance
In this research study the investigators want to find out if a non-invasive electrical brain stimulation method called RAVANS (also called tVNS) can have a beneficial effect on cognition in older individuals.
- Trial name
- WALLe (NCT04908358)
- Testing
- Active transcutaneous vagus nerve stimulation respiratory-gated non-painful electrical stimulation of the auricle for 10 minute sessions
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Alzheimer's Disease
The Detection of Early Dementia With the Digital Game Memory
The investigators are going to test if it is possible to detect early dementia with the digital game "memory". The investigators are going to test 15 healthy people and 15 patients with early dementia.
- Trial name
- NCT02041728
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Mild Cognitive Impairment (MCI), Healthy Aging
Computerized Cognitive Training in Healthy Older Adults and Mild Cognitive Impairment
The overall objective of this study is to assess the effect of an adaptive computerized cognitive training program for executive functions (CogniFit platform) on improving these functions in older adults, both healthy and with…
- Trial name
- COGNI-AGE (NCT07598409)
- Testing
- Computerized Cognitive Training, Active Control Computerized Activities
- Where
- 2 sites in Spain
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Universidad Antonio de Nebrija
Mild Cognitive Impairment
LifeBio Memory: Development of a Reminiscence Therapy Online Platform With Machine Learning to Increase Engagement
LifeBioMEMORY (LBM) is a reminiscence therapy (RT) mobile application that captures older adults' life stories in their own voices to promote social engagement and psychosocial well-being.
- Trial name
- LifeBio Memory (NCT07685067)
- Testing
- LifeBio Memory (LBM) digital reminiscence intervention
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- George Mason University
Epilepsy, Unspecified, Pharmacologically Resistant, Memory Impairment
Episodic Memory Before and After Surgery in Drug-resistant Partial Epilepsies
This study has two purposes: firstly, a better understanding of the neurobiological processes underlying episodic memory and, secondly, the development of useful clinical applications for epileptic patients, in particular the…
- Trial name
- MemO-Epi (NCT01919957)
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Schizophrenia
Pilot Study Using an NMDA Antagonist to Modulate Transcranial Direct Current Stimulation (tDCS) Effects on Sensory Discrimination
Transcranial direct current stimulation (tDCS) is a non-invasive form of brain stimulation which uses a very weak constant current to temporarily excite the brain area of interest via small electrodes placed on the scalp.
- Trial name
- NCT02426983
- Testing
- Direct Current Stimulation, Dextromethorphan
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Transcranial Direct Current Stimulation, Working Memory
Transcranial Direct Current Stimulation Effect on Pain Threshold and Working Memory: Impact of Age and Protocol Type
Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation method which has great potential as an aid in the therapeutic management of neuropsychiatric disorders and chronic pain syndromes.
- Conditions
- Transcranial Direct Current Stimulation, Working Memory, Pain
- Trial name
- NCT04328545
- Testing
- Anodal tDCS on DLPFC, Anodal tDCS on M1
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Alzheimer's Disease, Mild Cognitive Impairment
BEAM: Brain-Eye Amyloid Memory Study
The main objectives for this study are: 1. To investigate novel, non-invasive ocular measurements including optical coherence tomography and eye tracking in a cross-sectional study of participants with various neurodegenerative…
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Vascular Cognitive Impairment, Parkinson's Disease
- Trial name
- BEAM (NCT02524405)
- Testing
- Pittsburgh Compound B [11C]-PIB
- Where
- 5 sites in Canada
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
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