Clinical trials: Memory Reactivation
Sleep, Consolidation
Reactivating Specific Memories During Sleep in Conjunction with a Suppression Context
Forgetting is often perceived as the inability to retain information, but in fact at least some memory deterioration is due to active suppression processes, that are behaviorally adaptive.
- Trial name
- NCT04702750
- Testing
- Targeted memory reactivation (odors), Targeted memory reactivation (sounds)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Sleep, Consolidation
The Effects of Direct Context Reactivation During Sleep on Memory
The context in which memories are encoded is a major factor influencing how memories are organized. Individual memories are bound to the context (e.g., the location, time and state of mind in which they are encoded) and this…
- Trial name
- NCT04702152
- Testing
- Targeted memory reactivation (sounds)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Parkinson Disease, Aging
Role of Sleep on Motor Learning in Parkinson's Disease and Healthy Older Adults
People with Parkinson's disease (pwPD) often present difficulty consolidating newly learned skills into long-term memory. Sleep facilitates motor memory consolidation in healthy adults, especially in combination with targeted…
- Trial name
- TARGET-SLEEP (NCT04144283)
- Testing
- NAP, WAKE
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Sleep, Consolidation
Reinstatement of Context During Sleep and Its Subsequent Effect on Memory: an fMRI Study
Memory benefits from sleep and these benefits are putatively achieved through reactivation of the neural memory trace during sleep.
- Trial name
- NCT04702724
- Testing
- Targeted memory reactivation (sounds)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Phobia, Specific
Influence of Valproic Acid on Extinction-based Therapy in Patients With Fear of Spiders.
The purpose of this study is to evaluate whether valproic acid in combination with fear memory reactivation is useful to enhance treatment stability of exposure therapy for specific phobia.
- Trial name
- VALPRO (NCT02789813)
- Testing
- Valproic Acid, Fear reactivation, No fear reactivation
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Posttraumatic Stress Disorder
Emotional Memory Reactivation in Posttraumatic Stress Disorder
Converging lines of evidence have implicated the amygdala in the pathophysiology of posttraumatic stress disorder. The primary purpose of our study is to assess the effect of propanolol, a beta adrenergic antagonism, on amygdala…
- Trial name
- VIVITRAU (NCT01239173)
- Testing
- AVLOCARDYL
- Where
- France
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Memory Consolidation
The Impact of Reactivation During Sleep on the Consolidation of Abstract Information in Humans
In any given cognitive domain, representations of individual elements are not independent but are organized by means of structured relations.
- Trial name
- NCT05746299
- Testing
- Congruent vs. Incongruent, Immediate vs. Awake vs. Asleep, Targeted memory reactivation (TMR)
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Memory Reactivation, Memory Consolidation
Toward a Real-time Access to Sleepers' Mental Content
Sleep is crucial for global cognitive functioning, but its exact functions and mechanisms are still poorly understood. Cognitive studies of sleep typically rely on linking electrophysiological changes measured during sleep with…
- Conditions
- Memory Reactivation, Memory Consolidation, Sleepwalking
- Trial name
- SleepDance (NCT05452733)
- Testing
- differences of behavior between sleepwalking and non sleepwalking patient
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris