Clinical trials: Meniscus Tear, open to volunteers
Meibomian Gland Dysfunction, Dry Eye Syndromes
Ocular Surface Changes and Meibomian Gland Dysfunction in Rheumatologic Patients
This observational study aims to assess the frequency and severity of Meibomian Gland Dysfunction (MGD) and associated ocular surface changes in patients with systemic autoimmune rheumatic diseases compared with healthy…
- Conditions
- Meibomian Gland Dysfunction, Dry Eye Syndromes, Rheumatoid Arthritis, Systemic Lupus Erythematosus
- Trial name
- NCT07810569
- Volunteers
- 150 people
- Sponsor
- Assiut University
Meniscus Rupture, Meniscus Injury
Surgical Outcome After Displaced Bucket-handle Meniscal Lesions - Repair Versus Partial Meniscectomy
The menisci of the knee joint are structures composed of cartilage and connective tissue, whose primary functions are to stabilize the joint and distribute weight across joint surfaces.
- Conditions
- Meniscus Rupture, Meniscus Injury, Osteoarthritis of Knee
- Trial name
- NCT07079254
- Testing
- Meniscus suture, Partial meniscectomy
- Where
- 2 sites in Sweden
- Volunteers
- 300 people
- Sponsor
- Region Skane
Knee Injury, ACL Injury
Reducing Disparities in Knee Arthroscopy for Adolescents
Hundreds of thousands of youth athletes require surgery for knee injuries annually. The incidence of operative knee injuries has skyrocketed, but surgery can be delayed due to late recognition and barriers, such as insurance…
- Conditions
- Knee Injury, ACL Injury, Meniscus Tear, Hispanic or Latino
- Trial name
- RED KARD (NCT07580625)
- Testing
- Educational program and patient navigator
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Medial Meniscus Knee Injury
Evaluation of Different Patterns PHMM Root Tears
1. To evaluate and classify different morphological patterns of posterior horn medial meniscus root tears (PHMMRTs) and assess their correlation with clinical presentation, MRI findings, and arthroscopic features. 2.
- Trial name
- NCT07602985
- Testing
- MRI
- Volunteers
- 30 people
- Sponsor
- Assiut University
Corneal Topography, Dry Eye Syndromes
Performance Evaluation of the OCUTOP Hand-held Corneal Topographer
The OCUTOP is a new hand-held camera that photographs the front of the eye to map the shape of the cornea and to assess the tear film.
- Conditions
- Corneal Topography, Dry Eye Syndromes, Keratoconus, Healthy Volunteers
- Trial name
- OCUTOP (NCT07895849)
- Testing
- OCUTOP hand-held corneal topographer with OCUGRAPH software, Reference instrument measurement (corneal topography and tear-film assessment)
- Where
- 2 sites in United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Plymouth
Meniscus Tear
Novel Bioactive Sleeve on Pain and PROMs
A novel bioactive sleeve will be compared to a placebo sleeve with a similar look and feel to assess pain outcomes, patient reported outcome measures, and effectiveness of healing based on range of motion.
- Trial name
- NCT06041321
- Testing
- Reparel Sleeve
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Northwell Health
Meniscus Tear
The Effect of Centralization on Medial Meniscal Extrusion for Medial Meniscus Posterior Root Tear Repair
The purpose of this research is to determine if meniscus root repair with or without centralization will have an impact on postoperative pain, function, activity levels, patient satisfaction, and incidence of revision meniscus…
- Trial name
- NCT07388290
- Testing
- Medial meniscus posterior root tear (MMPRT) repair with meniscus centralization, Medial meniscus posterior root tear (MMPRT) repair without meniscus centralization
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- Mayo Clinic
ACL Injury, Meniscus Tear
MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction (MOCHA Trial)
This is a multicenter randomized, placebo-controlled trial to assess whether a 6-month course of oral montelukast after ACL reconstruction reduces systemic markers of inflammation and biochemical and imaging biomarkers of…
- Conditions
- ACL Injury, Meniscus Tear, Post-traumatic Osteoarthritis
- Trial name
- MOCHA (NCT04572256)
- Testing
- Montelukast
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Austin V Stone
Anterior Cruciate Ligament Injuries
How to Best Treat Anterior Cruciate Ligament Injuries
The project is a pragmatic registry-based RCT aiming to investigate ACL injury treatment. Study results will help fill knowledge gaps, facilitate shared decision making and strengthen patient treatment.
- Trial name
- NCT04770233
- Testing
- Early ACL reconstruction, Active rehabilitation
- Where
- 2 sites in Norway
- Volunteers
- 328 people
- Sponsor
- University Hospital, Akershus
Partial Meniscal Loss, Lateral Meniscus Partial Loss
Partial Meniscal Replacement with Spongioflex®
The purpose of this investigator-initiated trial is to evaluate whether the novel graft can prevent/reduce the disadvantages of the previously used replacement materials and shows better results than the group of patients, which…
- Conditions
- Partial Meniscal Loss, Lateral Meniscus Partial Loss, Medial Meniscal Partial Loss, Meniscus Lesion
- Trial name
- NCT06775197
- Testing
- partial meniscal replacement with Spongioflex®
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Maria-Josef-Hospital Greven
Meniscectomy, Meniscal Tears
Needle Arthroscopy vs Conventional Arthroscopy in Knees
This is a pilot randomized controlled trial will have 54 participants. The purpose of this study is to compare two surgical techniques to determine the differences in postoperative pain and early recovery in patients between…
- Conditions
- Meniscectomy, Meniscal Tears, Meniscal Repair, Chondral Lesion of the Knee
- Trial name
- Nano (NCT07823504)
- Testing
- Needle Arthroscopy
- Volunteers
- 54 people
- Sponsor
- Panam Clinic
Meniscus Tear
The Effect of Therapeutic Exercise on Cartilage Morphology and Physical Function for Individuals at High Risk of Knee Osteoarthritis
This randomized controlled trial aims to evaluate the efficacy of progressive resistance exercises (PRE) versus aerobic exercises on cartilage morphology and physical function in patients with degenerative meniscus tears.
- Trial name
- NCT06532851
- Testing
- Progressive Resistance Exercise (PRE), Aerobic Exercise, Control
- Where
- 2 sites in Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Unilateral Meniscus Tear of the Knee Joint
IIT Study on the Use of Medical Bio Glue for Repairing Meniscus Tears
To evaluate the safety and effectiveness of water triggered medical bioadhesive for meniscus tear repair
- Trial name
- NCT06878794
- Testing
- Using medical biological glue for filling And Using the meniscus suture system, Using the meniscus suture system
- Where
- China
- Volunteers
- 60 people
- Sponsor
- First Affiliated Hospital of Ningbo University
Meniscal Tears
Effects of Pulsed Electromagnetic Field Therapy on Meniscal Healing, Symptom Relief, and Knee Function
The goal of this clinical trial is to learn if pulsed electromagnetic field (PEMF) combined with home exercise improves healing and function in adults with meniscus tears. The main questions it aims to answer are: 1.
- Trial name
- NCT07117929
- Testing
- Active PEMF, Exercise
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
Meniscus Tear, Meniscus Disorder
Clinical Outcomes, Graft Longevity, and Chondral Protection Following Primary or Revision Meniscal Allograft Transplantation Surgery
The MERCuRE (MEniscus, REstoration, Conservation, and Repair) group is embarking on a 20-year follow-up study to evaluate the clinical outcomes, graft longevity, and chondral protection following primary or revision Meniscal…
- Conditions
- Meniscus Tear, Meniscus Disorder, Patient Satisfaction
- Trial name
- NCT06749431
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Joint Restoration Foundation, Inc.
Meniscus Tear
Outcomes of Meniscus Root Repair Using a Transtibial Pullout Technique
The results of this study will optimize the care for patients with a meniscus root tear. Surgeons will be able to determine if MRR (meniscus root repair) with transtibial pullout technique is an effective treatment and will…
- Trial name
- NCT03037242
- Testing
- Transtibial pullout technique
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- Mayo Clinic
Meniscus Tear
Bridge-Enhanced ACL Repair (BEAR) in Meniscus Repair
The bridge-enhanced ACL repair (BEAR) implant is a collagen-based scaffold loaded with whole blood. It is designed to promote healing in the setting of intraarticular knee pathology.
- Trial name
- NCT06041763
- Testing
- Meniscal Repair Procedure, BEAR Implant
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- NYU Langone Health
Knee Osteoarthristis, Meniscus Injury
Hemi-tibial Plateau Osteotomy Combined With Arthroscopic Repair for Medial Meniscus Posterior Root Tears in Varus Knees
This is a single-center clinical trial started by the study team. The goal is to compare two surgeries for people who have a varus knee alignment and a tear at the back attachment of the medial meniscus.
- Trial name
- NCT07356674
- Testing
- Hemi-tibial plateau osteotomy combined with arthroscopic repair, High tibial osteotomy combined with arthroscopic repair
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Eighth Affiliated Hospital, Sun Yat-sen University
Meniscus Tear, Meniscus Lesion
Clinical and Instrumental Assessment of Meniscal ROOT Tears Treated Through Suture to the Posterior Cruciate Ligament
The menisci are crucial for knee stability and functionality. Composed of fibrocartilaginous structure, they have an anatomical and biomechanical arrangement that makes them essential for load transmission and the prevention of…
- Conditions
- Meniscus Tear, Meniscus Lesion, Knee Injuries
- Trial name
- ROOT-PCL (NCT06507241)
- Where
- Italy
- Volunteers
- 59 people
- Sponsor
- Istituto Ortopedico Rizzoli
Meniscal Tear
This is a Study to Verify if Marrow Venting Procedure Can Improve Meniscal Suture Healing
Meniscal suture represents the current surgical practice, and marrow venting is a low risk procedure. Bone venting may be able to improve the outcome of meniscal repair, allowing the patient a better recovery.
- Trial name
- NCT05053646
- Testing
- Meniscal repair, Marrow venting procedure
- Where
- 2 sites in Switzerland
- Volunteers
- 80 people
- Sponsor
- Christian Candrian