Clinical trials: Metabolic Control
Obesity
A Retrospective Chart Review of Three Medifast Weight Control Centers
The primary aim of this study is to to retrospectively evaluate the efficacy of the MWCC Jump Start (Medifast's 5 \& 1) Plan on the following indices: weight loss, anthropometric changes, and reduction in common markers of…
- Trial name
- NCT01662830
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- Medifast, Inc.
Hypercholesterolemia
Lipid Lowering Effect of Plant Stanol Ester in a Spoonable Non-dairy Product
The aim is to determine the effect of investigational products on serum LDL cholesterol.
- Trial name
- NCT05064644
- Testing
- Product that contains plant stanol ester
- Where
- Finland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Raisio Group
Hypercholesterolemia
Safety, Tolerability, PK and PD of LGT209 in Healthy Volunteers and Patients With Hypercholesterolemia
This study is designed to measure the effects of LGT209 when given intravenously to patients with high cholesterol who are on stable doses of statin medications, and to healthy subjects with elevated cholesterol
- Trial name
- NCT01979601
- Testing
- LGT209
- Where
- 2 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Metabolic Syndrome
A Study to Determine the Safety and Efficacy of Oligopin® on Metabolic Risk Factors in Subjects With Metabolic Syndrome
The safety and efficacy of Oligopin® will be compared against a placebo to evaluate the effect on metabolic risk factors in subjects with metabolic syndrome.
- Trial name
- NCT04488653
- Testing
- Oligopin®
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Les Derives Resiniques et Terpeniques
Aging, Cardiovascular Diseases
Physical Inactivity Impacts on Blood Vessel Health and Glucose Levels in an Aging Population
Physical inactivity is known to increase post meal blood sugar levels in young, active populations. However, how quickly this may occur in active, older adults is not clear.
- Conditions
- Aging, Cardiovascular Diseases, Glucose Intolerance
- Trial name
- NCT04812392
- Testing
- Continuous Glucose Monitoring System
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Leryn Reynolds
Diabete Type 2, Obese
The Effect of Different Starches of Boba Pearls and Sugar Substitutes Used in Milk Tea on Glycaemia, Insulinaemia and Appetite Control (Pearl Study)
The first objective is to investigate the effect of boba pearls made from different starches on glycaemia, insulinaemia and appetite control.
- Trial name
- NCT04115657
- Testing
- Starch 1, Starch 2, Starch 3
- Where
- Singapore
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Cognitive Impairment, Poor Nutrition
The PROtein Enriched MEDiterranean Diet and EXercise Trial for Older Adults At Risk of Undernutrition
PROMED-EX is a single-blind, parallel group randomised controlled trial to determine the effect of a PROtein enriched MEDiterranean diet (PROMED) in comparison to a PROtein enriched MEDiterranean diet and EXercise (PROMED-EX)…
- Conditions
- Cognitive Impairment, Poor Nutrition, Cognitive Decline
- Trial name
- PROMED-EX (NCT05166564)
- Testing
- A Protein Enriched Mediterranean Diet (PROMED) Intervention, A Protein Enriched Mediterranean Diet & Exercise (PROMED-EX) Intervention
- Where
- United Kingdom
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Obesity
Safety Study of the Inhibition of Agouti-related Protein (AgRP) for the Management of Obesity and Weight Loss
Multiple pathways including peripheral and central hormones and neurotransmitters are involved in the regulation of food intake and body weight. One of the most studied pathways involves the melanocortin receptor.
- Trial name
- NCT00779519
- Testing
- TTP435
- Where
- 12 sites in United States, Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- vTv Therapeutics
Obesity
Korean Diet Efficacy Clinical Trial
To determine: 1. the acceptability of a Korean diet to an Australian overweight and obese population 2. which Korean recipes are easily prepared 3.
- Trial name
- NCT01124071
- Testing
- Provision of 2 Korean meals per day 6 days per week, Western Diet
- Where
- Australia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Sydney
Obesity, PreDiabetes
Network Meta-analysis of Intermittent Fasting and Cardiometabolic Risk
Intermittent fasting is a method of restricting calories over a defined period of time and includes regimens such as whole-day fasting, alternate-day fasting, and time-restricted feeding.
- Conditions
- Obesity, PreDiabetes, Diabetes, Hypertension
- Trial name
- NCT05309057
- Testing
- Intermittent Fasting
- Where
- 2 sites in Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Bone Loss
Prevention of Glucocorticoid Induced Impairment of Bone Metabolism
Glucocorticoid (GC) therapy is used to treat a variety of inflammatory conditions such as rheumatoid arthritis, inflammatory bowel disease, bronchial asthma, allergies, ankylosing spondylitis and some forms of cancers.
- Trial name
- NCT04767711
- Testing
- Lactobacillus reuteri ATCC PTA 6475 (L. reuteri 6475), Prednisolone
- Where
- Sweden
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Glucose Levels, Lipid Profile
Effects of Fasted- Versus Fed-exercise on Metabolic Health in Physically Active Adults
The purpose of this study is to investigate whether the sequence meal and exercise (exercise before meal or exercise after meal) affects the postprandial metabolism.
- Conditions
- Glucose Levels, Lipid Profile, Substrate Oxidation, Blood Pressure
- Trial name
- NCT06949709
- Testing
- Fasted-exercise, Fed-exercise
- Where
- Taiwan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Type 2 Diabetes Mellitus
Study of Efficacy, Weight Control, and Safety in Newly-diagnosed Type 2 Diabetes With Different Antidiabetic Therapy
Study Hypothesis：Compared with premixed insulin, triple oral combination therapy has similar hypoglycemic effect, better weight control and lower incidence of hypoglycemia.
- Trial name
- NCT03700801
- Testing
- Triple combination therapy group, Premixed insulin therapy group
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Bone Diseases, Metabolic, Osteoporosis, Postmenopausal
The Effects of Potassium Citrate on Bone Metabolism
Skeletal buffering of chronic acid loads may contribute to a significant amount of bone loss over time. Evidence from a few small short-term studies suggests that basic compounds, namely potassium citrate and potassium…
- Trial name
- NCT00357331
- Testing
- potassium citrate
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Childhood Obesity
The Optimising Family Engagement in HENRY (OFTEN) Study
This study will test whether parent engagement (recruitment, attendance) in a Childhood obesity prevention programme (HENRY) can be improved in local authorities randomised to receive an Optimisation intervention (in addition to…
- Trial name
- OFTEN (NCT02675699)
- Testing
- Optimisation + HENRY, HENRY as standard
- Where
- United Kingdom
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Leeds
High Blood Cholesterol Level
The Effect of Plant Sterol Supplement on Blood Cholesterol
The purpose of this study is to determine whether supplement of plant sterol could lower blood cholesterol.
- Trial name
- NCT00485095
- Testing
- Intake of plant sterols
- Where
- 2 sites in Norway
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Overweight, Childhood, Obesity in Children
The Bloom Study - a Safe and Healthy Start in Life
The aim of the Bloom Study is to promote healthy weight development among infants through a home-based health promoting intervention implemented in the Danish setting of community health nurses.
- Trial name
- NCT06705400
- Testing
- Multi-behavioural
- Where
- Denmark
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Dyslipidemia
Effect of Eggplant Extract on Lipid Profile During Fasting and Postprandial Period
The purpose of this study was to assess the effect of eggplant extract capsules on the lipid profile of healthy individuals after an oral lipid overload test in a randomized, double-blind, placebo-controlled clinical trial.
- Trial name
- NCT00845637
- Testing
- Eggplant extract
- Where
- Brazil
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Diabetic Ulcer
Evaluation of Topical Wound Oxygen (two2) Therapy
The purpose of this study is to evaluate the efficacy of the Topical Wound Oxygen (two2) therapy system on the healing of diabetic lower extremity ulcers.
- Trial name
- NCT00871312
- Testing
- Topical wound oxygen therapy
- Where
- 3 sites in United States, Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- AOTI Ltd.
Irritable Bowel Syndrome (IBS), Functional Dyspepsia
Interactive Effects of Early-Life Stress, Diet, and Metabolism on Gastrointestinal Dysfunction With Neuropsychiatric Symptoms
The goal of this observational case-control study is to learn how stressful experiences, dietary habits, and blood nutrient levels are associated with gastrointestinal symptoms and symptoms of depression and anxiety in adults…
- Conditions
- Irritable Bowel Syndrome (IBS), Functional Dyspepsia, Inflammatory Bowel Disease (IBD), Gastroparesis
- Trial name
- NCT07852819
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shandong University
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