Clinical trials: Metabolism, Lipids
Ketone Body, Lipid Metabolism
Acute Effects of MCT Formulations on Beta-Hydroxybutyrate Response, Lipid Profile, and Glucose Levels in Healthy Adults
The goal of this clinical trial is to evaluate the effects of medium-chain triglycerides (MCTs), delivered in different formulations, on beta-hydroxybutyrate response (as a marker of ketone body production), lipid metabolism, and…
- Conditions
- Ketone Body, Lipid Metabolism, Glucose Response
- Trial name
- NCT07718048
- Testing
- MCT Beverage, LCT Beverage, Synthetic MCT Powder
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Milan
Body Weight, Oxidative Stress
The Effect of a Meatless,Keto Restrictive Diet on Body Composition,Strength Capacity,Oxidative Stress,Immune Response
The subject of doctoral dissertation: Assessment of the effects of a meatless, ketogenic restrictive diet on body composition, strength capacity, oxidative stress and immune response During planning of research and topic of the…
- Conditions
- Body Weight, Oxidative Stress, Trimethylamine N-oxide, Immunologic Factors
- Trial name
- NCT05558488
- Testing
- Meatless, restrictive ketogenic diet
- Where
- Poland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Katarzyna Siedzik
Weight Loss, Blood Pressure
Feasibility & Implementation of a Plant-Based Weight-Loss Program in an Office-Based Setting
This prospective study aims to assess the feasibility and implementation of a plant-based, weight-loss program in an office setting.
- Conditions
- Weight Loss, Blood Pressure, Lipid Disorder, PreDiabetes
- Trial name
- NCT04091516
- Testing
- Low-fat plant-based diet
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Physicians Committee for Responsible Medicine
Lipid Metabolism, Postprandial Inflammation
Modulating Immune Responses After Consistent Lipid Exposure
Background of the study: Enhanced immune responses can lead to chronic hyperinflammation, which contributes to the development of non-communicable diseases such as type 2 diabetes and cardiovascular disease.
- Trial name
- MIRACLE (NCT07502898)
- Testing
- Dairy-derived breakfast shake consumption, Plant-derived breakfast shake consumption
- Where
- Netherlands
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Sleep Disturbance, Fatigue Syndrome, Chronic
Bao Yuan Tang Extract and Galactooligosaccharides for Sleep Regulation
Certain classical formulas in traditional Chinese medicine and dietary prebiotics have demonstrated beneficial effects on various aspects of suboptimal health status in previous studies.
- Conditions
- Sleep Disturbance, Fatigue Syndrome, Chronic, Endocrine Disorder, Glucose Metabolism Disorder
- Trial name
- NCT07774897
- Testing
- Combination product (Bao Yuan Tang full-component extract 2.0g and galactooligosaccharides 2.0g), Galactooligosaccharides 2.0g
- Where
- 6 sites in China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Chronodisruption, Shift Work Disorder
Impact of Shift Work on Glucose and Lipid Metabolism of Hospital Workers
The aim of the study is to evaluate circadian glucose, activity and dietary rhythms, as well as metabolic and cardiovascular risk associated with night shift work, sleep quality and well-being in a cohort of hospital staff…
- Conditions
- Chronodisruption, Shift Work Disorder, Glucose and Lipid Metabolism
- Trial name
- METASHIFT (NCT07426211)
- Where
- 2 sites in Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Olga Ramich (formerly Pivovarova)
Peripheral Vascular Disease, Lipid Disorder
Effect of Plasma Ceramides on Peripheral Vascular Function
The goal of this clinical trial is to determine the effect of elevated plasma ceramides on peripheral vascular function. Subjects will consume a high fat meal consisting of long chain fatty acids (to increase plasma ceramides) or…
- Conditions
- Peripheral Vascular Disease, Lipid Disorder, Endothelial Dysfunction
- Trial name
- NCT05107869
- Testing
- High Saturated Fat
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
De Novo Lipogenesis (DNL), Lipid Metabolism
Implementation and Validation of an Analytical Protocol for Measuring de Novo Lipogenesis in the Liver Using Stable Isotopes
During this study, an analytical protocol for measuring hepatic de novo lipogenesis (DNL) using deuterium oxide (²H₂O) will be implemented and validated in healthy participants.
- Conditions
- De Novo Lipogenesis (DNL), Lipid Metabolism, Stable Isotope Tracing, Healthy Volunteers (HV)
- Trial name
- DNL (NCT07742423)
- Testing
- Deuterium oxide
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Lipid Metabolism, Omega-3 Polyunsaturated Fatty Acids
Novel Approach to Increase EPA and DHA Levels
The goal of this intervention trial is to evaluate whether combining meldonium therapy with PUFAs (polyunsaturated fatty acids) supplements containing eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) changes the plasma…
- Conditions
- Lipid Metabolism, Omega-3 Polyunsaturated Fatty Acids, Supplementation
- Trial name
- NCT07304921
- Testing
- Meldonium + PUFA, PUFA + meldonium, PUFA supplementation only
- Where
- Latvia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riga Stradins University
Prediabetes, Insulin Resistance
Food and Metabolism Study
In this study, Investigators are interested in looking at the influence of eating avocados regularly, which are rich in healthy fats, fibers, and unique carbohydrates, on triglyceride and glucose metabolism in people with…
- Conditions
- Prediabetes, Insulin Resistance, Triglycerides, Lipids Metabolism
- Trial name
- FAM (NCT07624500)
- Testing
- Avocado meal plan, Control meal plan
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Satiety, Appetite
A Study of NatureU Burn on Satiety in Healthy Adults
This single-center, single-blind, non-randomized crossover exploratory study evaluated the short-term effects of NatureU Burn on postprandial satiety in healthy adults.
- Conditions
- Satiety, Appetite, Food Intake, Fat Disorder
- Trial name
- NUBURN (NCT07597382)
- Testing
- Glucose Reference Food, NatureU Burn Plus Glucose
- Where
- China
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- OmniSolutions Laboratory Holdings Limited
Lipid Disorders and Lipid Measurement
The Very Large Database of Lipids
Closer examination of granular lipid data in a large population offers numerous opportunities to generate new knowledge, ranging from studies examining concordance between commonly used lipid parameters to phenotypic…
- Trial name
- VLDL (NCT01698489)
- Where
- United States
- Volunteers
- 5,051,467 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Lipid Metabolism Disorders
Effect of Ilex Paraguariensis Harvest Time and Consumption Method of Processed Yerba Mate on the Lipid Profile
Introduction: This project studies the impact of Ilex paraguariensis harvest time, commonly known as yerba mate, and its consumption mode (mate, tereré, and mate/terere) on the lipid profile of consumers in the Department of…
- Trial name
- NCT06896175
- Testing
- Yerba mate consumption (Ilex paraguayensis) A, Yerba mate comsuption (ilex paraguayencis) B
- Where
- Paraguay
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Caaguazu
Obesity, Disorder of Lipid Storage and Metabolism
Identification of Novel Skeletal Muscle-derived Factors That Promote Lipid Oxidation (Columbus)
The purpose of this study is to collect data to help researchers identify factors, such as certain proteins or genetic codes, that are secreted from muscle that are associated with the beneficial effects of exercise.
- Conditions
- Obesity, Disorder of Lipid Storage and Metabolism, Lipid Metabolism Disorders, Metabolic Disorder
- Trial name
- Columbus (NCT01911091)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Obstructive Sleep Apnea, Fat Disorder
Metabolism and Sleep Apnea Treatment
The purpose of this research study is to see if obstructive sleep apnea (OSA) is associated with abnormalities in fat metabolism.
- Trial name
- MaST (NCT05539716)
- Testing
- PAP Therapy, Lifestyle Counseling Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Miami
Lipid Metabolism Disorders
The Genetic, Protein, and Lipid Basis of Variation in Cholesterol Efflux
The rationale of this research is that deep phenotyping of individuals at the extremes of cholesterol efflux will identify key determinants of efflux that are potential novel therapeutic targets to prevent or reverse…
- Trial name
- NCT04061018
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Healthy, Omega 3
Observing Metabolism of EPA With Consideration of Genetics And Sex
The goal of this clinical study is to learn how fast EPA is converted to other molecules, including DHA, with consideration of biological sex and genetics in healthy humans.
- Conditions
- Healthy, Omega 3, Metabolism, Lipids
- Trial name
- OMEGA (NCT06975241)
- Testing
- EPA 2.4g/day
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Dyslipidemia, Lipid Metabolism
Advanced Strategy of Food Supplements for the Optimization of Satiety and Lipid Metabolism in Maturity (SACIANS)
The SACIANS study (Advanced Strategy of Food Supplements for the Optimization of Satiety and Lipid Metabolism in Middle-Aged Adults) aims to evaluate the combined effect of commercially available food supplements on satiety and…
- Conditions
- Dyslipidemia, Lipid Metabolism, Satiety Response, Overweight and/or Obesity
- Trial name
- SACIANS (NCT07269795)
- Testing
- Food Supplement Combination (SACIANS Formula)
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Glucose and Lipid Metabolism
The Effects of 24-hour Fasting or Carbohydrate Restriction on Postprandial Metabolic Responses
Most individuals spend the majority of the day in a fed state, making postprandial blood glucose and lipid regulation a central component of metabolic health.
- Trial name
- NCT07250191
- Testing
- Fasting, Carbohydrate restriction
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Bath
Lipid Disorders
Lipoprotein Interactions and Platelet Function in Healthy Individuals and Those With Lipid Disorders
This study looks at how lipoproteins, which are particles in the blood that transport cholesterol, influence heart and blood vessel health.
- Trial name
- NCT06747000
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital