Clinical trials: Metastatic Cervical Cancer
Ovarian Cancer, Breast Cancer
Comprehensive Outcomes for After Cancer Health
This study intends to explore feasibility, acceptability, and outcomes related to the use of a digital health coaching intervention for individuals who have completed primary therapy for cancer.
- Conditions
- Ovarian Cancer, Breast Cancer, Lung Cancer, Gastric Cancer
- Trial name
- COACH (NCT05349227)
- Testing
- Digital Health Coaching Program, Fitbit
- Where
- 7 sites in United States
- Volunteers
- 625 people, healthy volunteers welcome
- Sponsor
- Pack Health
Head and Neck Cancer, Oral Cancer
Circulating Tumor Cell Counts in Postoperative ENE-Positive Oral Cavity Cancer Patients After Adjuvant CCRT
The aim 1 of this trial is the development of the Circulating tumor cells (CTCs) definition of oral cancer minimal residual disease (MRD), and aim 2 is a prospective trial of oral cancer treatment.
- Trial name
- NCT07296250
- Testing
- low-dose oral chemotherapy
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Head and Neck Squamous Cell Carcinoma, Anal Cancer
Blood Biomarkers Based Screening for HPV-driven OPC
The objective of our study is to demonstrate that it is possible to detect and treat human papilloma virus (HPV)-related oropharyngeal cancers (OPC) early using simple blood tests.
- Conditions
- Head and Neck Squamous Cell Carcinoma, Anal Cancer, Human Papilloma Virus
- Trial name
- SCREEN-HPV (NCT06528353)
- Testing
- HPV16-E6 serology and HPV ctDNA
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- UNICANCER
Adenoid Cystic Carcinoma, Salivary Gland Cancer
A Study of Sunitinib in Recurrent and/or Metastatic Adenoid Cystic Carcinoma of the Salivary Glands
This is a phase II study to evaluate the effectiveness of study drug sunitinib malate in patients with recurrent and/or metastatic adenoid cystic carcinomas of the salivary gland.
- Trial name
- NCT00886132
- Testing
- Sunitinib
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Recurrence, Metastasis
The Clinical Relevance of Immune Cells and CTC in HNSCC Patients
Head and neck squamous cell carcinomas (HNSCCs) are mainly caused by tobacco, alcohol consumption and betel nut chewing and the sixth most common cancer in the world.
- Conditions
- Recurrence, Metastasis, Death
- Trial name
- NCT02420600
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
HNSCC
WGA in Platinum-refractory HNSCC Underwent Nivolumab
To choose a subgroup who could clearly benefit from Nivolumab, we are proposing a prospective observational study. Whole-genome study (WGS) analysis will be performed on archived cancer tissues from patients who were (1)…
- Trial name
- NCT03917537
- Testing
- HNSCC patients have used Nivolumab
- Where
- 2 sites in Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Head and Neck Cancer, Lymphoma
SUper-Resolution Ultrasound Imaging of Erythrocytes (SURE) in Normal and Malignant Lymph Nodes
The goal of this observational study is to visualize the small vessels in normal and cancerous lymph nodes on the neck with a new ultrasound technique.
- Conditions
- Head and Neck Cancer, Lymphoma, Lymph Node Metastasis
- Trial name
- NCT05754814
- Testing
- Malignant lymph nodes
- Where
- 2 sites in Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Head and Neck Cancer
Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants
RATIONALE: Collecting and storing samples of tissue, saliva, and blood from patients with cancer and from healthy participants to study in the laboratory may help the study of cancer in the future.
- Trial name
- NCT00898638
- Testing
- biologic sample preservation procedure, medical chart review
- Where
- 4 sites in United States
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Circulating Tumor Cell, Squamous Cell Carcinoma of the Head and Neck
CTC Detection Rate in SCCHN With a in Vivo Device
Detection rate and isolation yield of CTC is low in squamous cell carcinoma of head and neck (SCCHN) with in vitro approaches rely on limited sample volumes.
- Trial name
- NCT03071900
- Testing
- circulating tumor cell analysis
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nanjing Tongren Hospital
Oncology
Pretreatment Quality of Life as a Predictor of Distant Metastasis-Free Survival and Overall Survival in Patients With Head and Neck Cancer
This study shed light on an under-researched area by examining the prognostic associations of pre-treatment QoL with overall survival and distant metastasis free survival among patients with head and neck cancer who underwent…
- Trial name
- NCT03290352
- Testing
- Questionnaire
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Esophageal Cancer
Mechanistic Study on the Diagnosis of Esophageal Cancer Lymph Node Metastasis Using Spectral CT, Multimodal MRI, FAPI PET-CT, Pathology, and AI Evaluation System
The objective of this study is to address the urgent issues in the diagnosis of lymph node metastasis in esophageal cancer. By employing multimodal MRI, spectral CT imaging and FAPI PET-CTtechniques, the study will correlate…
- Trial name
- NCT06818214
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Henan Cancer Hospital
Caregiver, Head and Neck Carcinoma
Geriatric and Quality of Life Assessments in Older Patients With Non-metastatic or Metastatic Head and Neck or Lung Cancer Undergoing Surgery or Chemoradiation and Their Caregivers
This trial studies comprehensive geriatric and quality of life assessments in older patients with head and neck or lung cancer that has or has not spread to other parts of the body who are undergoing standard surgery or…
- Conditions
- Caregiver, Head and Neck Carcinoma, Lung Carcinoma, Metastatic Head and Neck Carcinoma
- Trial name
- NCT03902535
- Testing
- Comprehensive Geriatric Assessment, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Non-small Cell Lung Cancer, Esophageal Cancer
Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers
Patients with resectable solid primary cancers and even limited number of metastases are potentially curable. However, most patients develop recurrences despite surgery.
- Conditions
- Non-small Cell Lung Cancer, Esophageal Cancer, Gastric Cancer, Pancreatic Cancer
- Trial name
- NCT02838836
- Testing
- Study sample collection
- Where
- United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Oral Leukoplakia, Autofluorescence
Identification of Oral Lesions Through an Autofluorescence System
The aim of the study will be to evaluate the efficacy of a tissue autofluorescence detection system as an aid to clinical screening in identifying lesions of the oral mucosa.
- Conditions
- Oral Leukoplakia, Autofluorescence, Secondary Prevention, Keratosis
- Trial name
- NCT05942794
- Testing
- Screening examination
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Federico II University
Cervical Cancer Squamous Cell, Human Papilloma Virus Infection
Hybrid Capture Test on Mobile Unit Program to Improve Cervical Cancer Screening in Brazilian Rural and Remote Areas
This study evaluates the women cervical samples through molecular tests in order to: 1. Deploy the test careHPV (hybrid capture test) in mobile unities of the Barretos Cancer Hospital to evaluate their performance;
- Conditions
- Cervical Cancer Squamous Cell, Human Papilloma Virus Infection, Human Papilloma Virus-Related Carcinoma, Prevention
- Trial name
- careHPV (NCT01539668)
- Where
- 2 sites in Brazil
- Volunteers
- 5,079 people, healthy volunteers welcome
- Sponsor
- Barretos Cancer Hospital
Papillary Thyroid Cancer
Treatment Efficacy and Safety of Low-dose Radioiodine Ablation for Intermediate-risk Differentiated Thyroid Carcinoma
Primary objective: The 3-years disease-free survival was compared between low-dose group (30 mCi) and high-dose group (100 mCi).
- Trial name
- NCT04354324
- Testing
- Radioiodine
- Where
- China
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Metastatic Melanoma, Metastatic Breast Cancer
Quantifying Systemic Immunosuppression to Personalize Cancer Therapy
It is nowadays well established that the immune system can profoundly influence disease outcome in cancer patients. Increasing evidence is indeed showing that patients displaying spontaneous T cell-mediated immune response…
- Conditions
- Metastatic Melanoma, Metastatic Breast Cancer, Advanced Renal Cell Carcinoma, Squamous Cell Carcinoma of Head and Neck
- Trial name
- SERPENTINE (NCT04941365)
- Testing
- single arm
- Volunteers
- healthy volunteers welcome
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Head and Neck Cancer, Psychosocial Effects of Cancer and Its Treatment
Measuring Patient Satisfaction With Facial Appearance: Development and Validation of a New Patient-Reported Outcome Measure
RATIONALE: Developing a questionnaire that patients can use to assess their quality of life related to the appearance of their face after surgery may help doctors plan the best treatment for patients undergoing surgery and…
- Trial name
- NCT00530049
- Testing
- questionnaire administration, assessment of therapy complications, psychosocial assessment and care
- Where
- 4 sites in United States, Canada and 1 more
- Volunteers
- 1,745 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cervical Cancer
Pilot Study of a Mobile Health Approach to Reduce Barriers to Cervical Cancer Screening in Tanzania
The purpose of this study is to determine whether motivational text messages and/or travel vouchers are effective in increasing cervical cancer screening rates in urban and rural regions of Northern Tanzania.
- Trial name
- KCCPAS (NCT02680613)
- Testing
- Motivational SMS, Travel Voucher
- Where
- Tanzania
- Volunteers
- 851 people, healthy volunteers welcome
- Sponsor
- Queen's University
HPV-Related Carcinoma
Integrating Primary & Secondary Interventions for Cervical Cancer Prevention in Primary Care Settings
The purpose of this study is to determine whether a mobile health educational intervention for Human PapillomaVirus (HPV) Vaccination promotion and cervical cancer screening in Primary Care settings is a feasible behavioral…
- Trial name
- NCT03033550
- Testing
- brief negotiated mobile application
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center