Clinical trials: Microbiological Study
Sepsis, Septic Shock
Ultrasound-guided Blood Sampling Drawing for Microbiological Analysis in the Critically Ill
This study will test the feasibility of ultrasound-guided sterile blood sampling for critically ill patients with suspected sepsis requiring blood culture.
- Conditions
- Sepsis, Septic Shock, Infections, Diagnosis
- Trial name
- ECOVEN (NCT06156072)
- Testing
- Ultrasound-guided venipuncture
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Treatment, Periodontitis, Apical
Treatment of Young Permanent Teeth With Different Adjuvant Approaches
To determine microbiology assessment of infected root canal in young permanent teeth, as well as antimicrobial efficiency of different adjuvant treatment modalities including photodynamic therapy (PDT), high-power diode laser…
- Conditions
- Treatment, Periodontitis, Apical, Necrotic Pulp
- Trial name
- NCT05291195
- Testing
- Laser-device group, Essential Oil, Sodium hypochlorite group
- Where
- Serbia
- Volunteers
- 40 people
- Sponsor
- University of Belgrade
Peri-implantitis, Periodontal Disease
Implant Surface Decontamination in Peri-implantitis Treatment
Peri-implantitis is an infectious disease that resides in the mucosa surrounding dental implants and also affects the supporting bone.
- Trial name
- NCT01521260
- Testing
- Chlorhexidine
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- University Medical Center Groningen
Infection, Skin and Subcutaneous Tissue Bacterial Infections
Study of Accuracy of New Diagnostic Technology to Determine Guide Rapid Antibiotic Treatment for Serious Infections
Military service members and the U.S. veteran population face a growing and serious health threat: widespread antibiotic resistance resulting from resistant bacteria and a dwindling pipe-line of sufficiently potent antibiotics.
- Conditions
- Infection, Skin and Subcutaneous Tissue Bacterial Infections, Healthcare-associated Infection, Infection Due to Resistant Bacteria
- Trial name
- RAMPED (NCT02060513)
- Where
- 3 sites in United States
- Volunteers
- 2,298 people
- Sponsor
- Connie Price
Bacterial Conjunctivitis
Study of Efficacy of Levofloxacin 0.5% Ophthalmic Solution Administered Three Times a Day for Bacterial Conjunctivitis
The aim of the study is to evaluate the clinical and microbiological efficacies of three times daily administration of levofloxacin 0,5% eye drops as compared to the more frequent dosing (up to 8 times a day during the first 2…
- Trial name
- NCT00565123
- Testing
- 0.5% levofloxacin eye drops
- Where
- Poland
- Volunteers
- 119 people
- Sponsor
- Laser Microsurgery Centre, Poland
Diabetes, Infection
Technology That Permits Focal Dose of Antibiotics to be Delivered to Lower Limb(s) of Diabetic Patients
The use of the Percutaneous Isolated Limb Procedure (PILP) which enables the use of existing antibiotic therapies in a more targeted and concentrated fashion in patients with diabetes who have a significant lower limb infection…
- Trial name
- NCT02158442
- Testing
- Percutaneous Isolated Limb Perfusion (PILP) delivery, Timentin
- Where
- Australia
- Volunteers
- 15 people
- Sponsor
- Osprey Medical, Inc
Adult Patient (Over 18 Yr-old) Admitted to the ICU for Acute Peritonitis
Evaluation of BD Glucan in Peritoneal Fluid for the Diagnosis of Fungal Peritonitis
Invasive candidiasis has a high mortality rate, around 40%. Outcome remains tightly linked to the time of treatment administration.
- Trial name
- PERICAND (NCT03469401)
- Testing
- Intervention
- Where
- France
- Volunteers
- 126 people
- Sponsor
- Hospices Civils de Lyon
Bronchiectasis, Periodontal Disease
Evaluation of Periodontal Treatment in Patients With Bronchiectasis
Background: Association between periodontal disease (PD) and chronic obstructive pulmonary disease (COPD) has been widely studied and the aspiration of periodontal pathogens is one of the most accepted causal mechanisms for…
- Trial name
- NCT02514226
- Testing
- supragingival treatment, periodontal treatment, periodontal treatment and photodynamic therapy
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Nove de Julho
Periodontal Disease
Study on Biomarkers of Periodontitis and Type 2 Diabetes Mellitus in Males and Females 30 - 70 Years of Age
The purpose of this study is to learn about the interactions of markers of type 2 diabetes (T2DM) and periodontitis (PD). Study VPE00001 is a multi-center cross-sectional study.
- Trial name
- NCT06582056
- Testing
- Investigational Procedure
- Where
- 4 sites in United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Disorders of the Eye Following Cataract Surgery
Microbiological Evaluation of the Ocular Flora Before Cataract Surgery
The purpose of the present study is to elucidate the spectrum of ocular flora and their antimicrobial susceptibility profiles in patients undergoing routine cataract surgery.
- Trial name
- NCT02124603
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- SIFI SpA
Dental Caries
Phase 2 Study to Evaluate the Microbiology and Safety of C16G2 Administered to Adult and Adolescent Dental Subjects
The purpose of this study is to evaluate if C16G2 Gel administered over a certain period of time either with a toothbrush or a custom dental tray can effectively kill bacteria in the mouth that cause dental cavities.
- Trial name
- NCT02594254
- Testing
- C16G2 Gel
- Where
- 10 sites in United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Armata Pharmaceuticals, Inc.
Patients Scheduled for Any Oral Surgical Flap Procedure That Require Suturing Will be Included in This Study
Effect of Topical Active Oxygen Therapy on Surgical Site Wound Healing and Microbial Colonization
To assess the antibacterial efficiency of oxygenated gel therapy on wound healing and microbiological colonization around surgical sutures
- Trial name
- NCT06705920
- Testing
- topical oxygen gel
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Staphylococcal Infection
Study to Assess Eradication of Nasal Carriage of Staphylococcus Aureus (SA) With Mupirocin (Bactroban 2% Nasal Ointment)
This study will assess the nasal eradication of SA in healthy subjects following treatment with mupirocin 2% (Bactroban 2% Nasal Ointment) twice daily for 5 days, by means of a broth enriched culture microbial assay.
- Trial name
- NCT02284555
- Testing
- Mupirocin
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Destiny Pharma Plc
Stage III Periodontitis
Antimicrobial Photodynamic Therapy With ICG-Loaded Nanoparticles for Periodontitis Management
To better understand and treat your gum disease, dentists now use a system that stages its severity and grades its speed, rather than using old labels.
- Trial name
- NCT07316023
- Testing
- Non- surgical periodontal therapy followed by photodynamic therapy with ICG-loaded nanoparticles, Non- surgical periodontal therapy followed by photodynamic therapy with ICG-loaded macroparticles, Non- surgical periodontal therapy only
- Where
- Egypt
- Volunteers
- 27 people
- Sponsor
- Nada Mahmoud Soliman
Pulmonary Disease, Chronic Obstructive
To Evaluate the Safety, Tolerability, Pulmonary Deposition, Pharmacokinetics and Pharmacodynamics of Ciprofloxacin Inhale in Japanese Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD, GOLD II-III)
The study will be conducted in a single-center, randomized, single-blinded, placebo-controlled, dose escalation design with two dose groups.Multiple-dose inhalation of Ciprofloxacin inhale 50 and 75 mg or placebo will be…
- Trial name
- NCT01072942
- Testing
- Ciprofloxacin (Cipro InhaIe, BAYQ3939)
- Where
- Japan
- Volunteers
- 16 people
- Sponsor
- Bayer
Pancreatic Surgery, Antibiotic Prophylaxis
Impact of Antibiotic Prophylaxis Change on Surgical Site Infections After Pancreaticoduodenectomy
Patients undergoing pancreaticoduodenectomy after preoperative biliary drainage are at increased risk of surgical site infections (SSI) due to bile colonization.
- Conditions
- Pancreatic Surgery, Antibiotic Prophylaxis, Surgical Site Infection (SSI), Surgical Site Infection Prevention
- Trial name
- ICADI (NCT07531420)
- Where
- France
- Volunteers
- 117 people
- Sponsor
- Central Hospital, Nancy, France
Multiple Sclerosis, Periodontitis
Periodontal Health Profile in Multiple Sclerosis Patients
This study aims to evaluate the periodontal status of patients with Multiple Sclerosis (MS) through clinical, microbiological, and biochemical parameters.
- Trial name
- NCT07412431
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Periodontal Pocket
Ozonized Olive Oil in the Treatment of Periodontal Pockets
A randomized controlled clinical trial was conducted on 16 patients (8 males and 8 women) who were diagnosed chronic periodontitis.
- Trial name
- NCT06980675
- Testing
- Activated Ozonized Olive Oil Gel
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bari
Periodontitis, Clindamycin Gel
Comparing Aloe Vera Gel and Clindamycin Gel Added to Scaling and Root Planing for Periodontitis
Periodontitis is an inflammatory disease affecting the tissues that support the teeth. Scaling and root planing is a standard nonsurgical treatment, but additional local treatments may help improve clinical periodontal outcomes…
- Conditions
- Periodontitis, Clindamycin Gel, Aloe Vera Gel, Scaling and Root Planing
- Trial name
- NCT07900802
- Testing
- Scaling and Root Planing
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Peri-implant Mucositis
A Topical Desiccant Agent in Association With Manual Debridement in the Treatment of Peri-implant Mucositis
In patients presenting peri-implant mucositis, effective sub-mucosal debridement is crucial to prevent peri-implantitis. The aim of this pilot study was to assess the 3-month clinical and microbiological effects of a locally…
- Trial name
- NCT03858959
- Testing
- topical agent
- Where
- Italy
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Universita di Verona