Clinical trials: Microsomia
Preeclampsia and Intrauterine Growth Restriction
Placental Insufficiency Microcirculation Quantification by Ultrafast Doppler (MICRODOPPLER PLACENTA)
To identify fetuses small for their gestational-age who have reached their appropriate growth potential from growth-restricted fetuses due to placental insufficiency is uneasy.
- Trial name
- NCT03860103
- Where
- France
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Premature Birth, Preeclampsia
A Randomized Trial of Docosahexaenoic Acid Supplementation During Pregnancy to Prevent Deep Placentation Disorders
This study evaluates the effectiveness of maternal supplementation with Docosahexaenoic acid (DHA) early in pregnancy to reduce the incidence of deep placentation disorders: preterm birth, preterm labor, preterm premature rupture…
- Conditions
- Premature Birth, Preeclampsia, Fetal Growth Retardation, Stillbirth
- Trial name
- NCT02336243
- Testing
- Docosahexaenoic acid (DHA)
- Where
- 5 sites in Chile
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Fasting, Fetal Growth Retardation, Antenatal (Disorder)
Can Fasting Ramadan in the Third Trimester in Pregnancy Affects the Fetal Growth.
Prospective comparative cohort study including 159 pregnant women at the third trimester recruited from the antenatal clinic at EL-Demerdash outpatient clinic, and followed up during the holy month of Ramadan (from 18th June To…
- Trial name
- NCT03246711
- Testing
- Fasting
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Fetal Growth Retardation, Fetal Macrosomia
A Comparative Study of AI Methods for Fetal Diagnostic Accuracy in Ultrasound
This study serves as a supplemental investigation to the randomized controlled SCAN-AID study (NCT0632187). This study will evaluate and compare the fetal growth estimation outcomes of AI-supported groups, expert sonographers…
- Conditions
- Fetal Growth Retardation, Fetal Macrosomia, Fetal Growth
- Trial name
- NCT06268392
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Sleep, Pregnancy
Halifax PrenaBelt Trial
Back and right-sided sleeping position in pregnant women has recently emerged as a potential risk factor for low birthweight (LBW) and stillbirth (SB) in the medical literature.
- Conditions
- Sleep, Pregnancy, Stillbirth, Infant, Low Birth Weight
- Trial name
- NCT02377817
- Testing
- PrenaBelt
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Allan Kember
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Infant Development
Maternal Adversity, Vulnerability and Neurodevelopment
Maternal Adversity Vulnerability and Neurodevelopment (MAVAN) project is a prospective community-based, pregnancy and birth cohort of Canadian mother-child dyads.
- Conditions
- Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Infant Development, Infant Behavior
- Trial name
- MAVAN (NCT03434457)
- Where
- Canada
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Pregnancy Related, Substance Use
The Impact of Opioid and Cannabis Exposure on Fetal Growth
Individually, both opioid and cannabis exposure during pregnancy are associated with changes in fetal growth. The extent to which opioid and cannabis exposure affect fetal growth is unknown.
- Conditions
- Pregnancy Related, Substance Use, Fetal Growth Retardation, Placenta Diseases
- Trial name
- IMPACT (NCT05899101)
- Where
- 5 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dr. Laura Gaudet
Fetal Growth Retardation, Fetal Neurodevelopmental Disorder
Evaluation of Anterior Middle Brain Structures With Cerebrovascular Flow in Fetuses With Fetal Growth Restriction
The study will be conducted to examine the effects of abnormal growth pattern and cerebrovascular blood flow measurements on fetal frontal lobe development with the advancing ultrasound technology.
- Trial name
- NCT06215690
- Testing
- Ultrasound measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Preeclampsia, Intrauterine Growth Restriction
sFlt1/PlGF and Planned Delivery to Prevent Preeclampsia at Term.
Preeclampsia (PE) affects ~5% of pregnancies. Although improved obstetrical care has significantly diminished associated maternal mortality, PE remains a leading cause of maternal morbidity and mortality in the world.
- Conditions
- Preeclampsia, Intrauterine Growth Restriction, Maternal Hypertension, Neonatal Outcome
- Trial name
- PE37 (NCT04766866)
- Testing
- sFlt1/PlGF screening in maternal blood at 35 to 36.6 weeks of gestation
- Where
- 21 sites in Belgium, Colombia and 7 more
- Volunteers
- 9,132 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Pre-eclampsia, Gestational Diabetes Mellitus (GDM)
Placental Biology in Health and Disease
Pre-eclampsia (PET) is a condition characterised by high blood pressure and damage to other organs, and is a leading cause of maternal and fetal complications such as fetal growth restriction (FGR).
- Conditions
- Pre-eclampsia, Gestational Diabetes Mellitus (GDM), Fetal Growth Restriction (FGR), Pregnancy Induced Hypertension (PIH)
- Trial name
- NCT07470320
- Testing
- There are no interventions for this study
- Where
- United Kingdom
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Pre-eclampsia, Intra-uterine Growth Retardation
EG-VEGF : Potential Marker of Pre-eclampsia and / or Intrauterine Growth Restriction
The purpose of this study is to assess the potential prognostic value of seric concentrations of EG-VEGF for Pre-eclampsia and/or intrauterine growth restriction and will allow checking whether plasma levels of EG-VEGF at 14-18…
- Trial name
- EGEVE (NCT01490489)
- Testing
- blood sample and doppler Ultrasound of uterine arteries
- Where
- France
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Small for Gestational Age, Infant, Very Low Birth Weight
Effect of Low Dose Aspirin on Birthweight in Twins: The GAP Trial.
Low-dose aspirin started in the first-trimester has been associated with a decrease of preeclampsia, fetal growth restriction and preterm birth in high-risk pregnancies.
- Conditions
- Small for Gestational Age, Infant, Very Low Birth Weight, Fetal Growth Retardation, Preeclampsia
- Trial name
- GAP (NCT02280031)
- Testing
- Acetylsalicylic Acid
- Where
- 2 sites in Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Intrauterine Growth Restriction
Correlation of Uterine and Umbilical Arteries Doppler With Placental Pathology in IUGR
When indicated, a conservative management plan of IUGR was undertaken. Doppler studies were performed within the last week before delivery The results of Umbilical artery (UA) Doppler velocimetry were categorized as normal …
- Trial name
- NCT03081754
- Testing
- Doppler velocimetry
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ahmed Maged
Pre-eclampsia, Intrauterine Growth Retardation
A Modernized Approach to Prenatal Care in Low Risk Women
The investigators plan to identify 80 pregnant women at low risk for obstetrical complications and replace 4-5 routine third trimester visits with a structured program of home weight, blood pressure and urine protein monitoring…
- Trial name
- NCT01606774
- Testing
- Modernized prenatal care
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pregnancy Related, Remote Monitoring
Feasibility of Remote eCTG Monitoring Home@Hospital in Complicated Pregnancies
The objective of this single center, interventional cohort study is to evaluate the feasibility of remote electrophysiological cardiotocography (eCTG) monitoring in complicated pregnancies in a home@hospital setting.
- Conditions
- Pregnancy Related, Remote Monitoring, Feasibility
- Trial name
- HASTA (NCT06859177)
- Testing
- Remote eCTG
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Stillbirth, Infant, Low Birth Weight
UniSA BackOff! Study: Adelaide PrenaBelt Trial
Stillbirth (SB) is a devastating complication of pregnancy and contributes to over 2 million deaths globally every year. Over 20 million infants are born every year with low birth weight (LBW), which is associated with a twenty…
- Conditions
- Stillbirth, Infant, Low Birth Weight, Infant, Very Low Birth Weight, Sleep-Disordered Breathing
- Trial name
- NCT04437407
- Testing
- PB2-1 prototype, PB2-2 prototype, PB2-3 prototype
- Where
- Australia
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Shiphrah Biomedical Inc.
Pre-Eclampsia, Pre-Term
Vascular Inflammation and Anti-inflammatory Supplements After Adverse Pregnancy Outcomes
Women who had an adverse pregnancy outcome (APO), such as preeclampsia, preterm birth, or gestational diabetes, have a higher risk for heart disease.
- Conditions
- Pre-Eclampsia, Pre-Term, Intrauterine Growth Restriction, Hypertension in Pregnancy
- Trial name
- VIA (NCT04633551)
- Testing
- Anti-inflammatory supplement
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Pregnancy, Fetal Macrosomia
Correlation Between Placental Thickness in the Second and Third Trimester and Fetal Weight
The aim of this prospective longitudinal study was to investigate the relationship between placental thickness during the second and third trimesters and placental and birth weights.
- Conditions
- Pregnancy, Fetal Macrosomia, Intrauterine Growth Restriction
- Trial name
- NCT02473991
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 395 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Fetal Growth Restriction, Perinatal Outcome
Relationship of DV Doppler Parameters to Perinatal Outcomes in IUGR vs Non-IUGR
This observational study investigates whether blood flow in the ductus venosus, a small fetal vein measured by Doppler ultrasound, is related to pregnancy outcomes.
- Conditions
- Fetal Growth Restriction, Perinatal Outcome, Pregnancy, High Risk
- Trial name
- DV-FGR (NCT07190157)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Izmir City Hospital
Fetal Macrosomia, Intrauterine Growth Disorders (IUGR and Macrosomia)
Estimation of Fetal Weight by Measuring Abdominal Circumference, Abdominal Subcutaneous Soft Tissue Thickness, Femur Length and Mid-thigh Soft Tissue Thickness
Traditional methods for estimating fetal weight (EFW) often miss the mark because they focus on bone and circumference while ignoring fetal fat. This study proposes a more inclusive formula to fix that.
- Conditions
- Fetal Macrosomia, Intrauterine Growth Disorders (IUGR and Macrosomia), Intrauterine Growth Restriction (IUGR)
- Trial name
- NCT07575152
- Testing
- 3rd trimester ultrasound examination within 48-72 hours of delivery
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Assiut University