Clinical trials: Midazolam Premedication
Diagnostic Esophagogastroduodenoscopy
Premedication With Alprazolam and Midazolam for Upper Gastrointestinal Endoscopy
Diagnostic upper GI endoscopy can be uncomfortable and stressful for many patients. Various methods are available for sedation during this procedure.
- Trial name
- NCT03130842
- Testing
- Sublingual alprazolam, Oral midazolam
- Where
- Iran
- Volunteers
- 136 people
- Sponsor
- Isfahan University of Medical Sciences
Premedication, Anaesthesia
Melatonin Premedication in Children Undergoing Surgery
Melatonin has been proposed as alternative to midazolam as a premedication in procedures preceding anaesthesia induction. The objective of this prospective, randomized, double-blind study is to investigate the possible effect of…
- Trial name
- NCT02265822
- Testing
- melatonin in children premedication, midazolam in children premedication
- Volunteers
- 92 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Anesthesia
Intranasal Dexmedetomidine Versus Intranasal Midazolam as a Premedication in Pediatrics Undergoing Upper GI Endoscopy
compare the effectiveness of intranasal dexmedetomidine and midazolam as a premedication in sedation of preschool children in GI endoscopy
- Trial name
- NCT06181682
- Testing
- Dexmedetomidine, Midazolam
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anesthesia Complication
Effect of Midazolam Premedication on Opioid-induced Mask Ventilation Difficulty
Mask ventilation has great importance during anesthesia induction because it is the only way to oxygenate patients who have lost consciousness and spontaneous breathing.
- Trial name
- NCT05369819
- Testing
- Midazolam, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Karaman Training and Research Hospital
Adenotonsillectomy, Preoperative Anxiety
Timing Of Midazolam İn Children Undergoing Adenotonsillectomy: Effects On Stress, Cortisol, And Recovery
This study is a prospective, randomized, controlled clinical trial designed to evaluate the optimal timing of midazolam administration in children undergoing adenotonsillectomy.
- Conditions
- Adenotonsillectomy, Preoperative Anxiety, Surgical Stress Response, Postoperative Pain
- Trial name
- Timing-Midazol (NCT07622641)
- Testing
- Midazolam (Oral), Midazolam (Intravenous)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Erzurum City Hospital
Cystoscopy
Premedication With Oral Midazolam in Patients Undergoing Rigid Cystoscopy: A Randomized, Double-blind, Placebo-controlled Trial
To investigate the efficacy of oral midazolam for patients undergoing rigid cystoscopy in: 1. relieving patient's anxiety and improving satisfaction 2. reducing procedure-related pain 3.
- Trial name
- NCT00563069
- Testing
- Midazolam
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Hospital Authority, Hong Kong
Respiratory Distress Syndrome
Propofol Versus Midazolam as Premedication for Preterm Neonates With Respiratory Distress Syndrome (RDS)
The aim of the study is to compare the intubation conditions among propofol and remifentanil versus midazolam and remifentanil in premature neonates with respiratory distress syndrome.
- Trial name
- NCT00797160
- Testing
- propofol
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of Minas Gerais
Midazolam
Pharmacokinetic Evaluation of MDZ028
Plasma concentration data were collected from 37 paedriatic patients and 12 healthy adults recruited in a single dose, open-label phase II pharmacokinetic study and in a single dose, randomised, open-label two-peiod crossover…
- Trial name
- MIDAZOLAM (NCT03639428)
- Testing
- Midazolam
- Volunteers
- 37 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Anxiolytic Effect, Virtual Reality Immersion
Anxiolytic Effect of Virtual Reality Immersion Versus Midazolam Premedication in Patients Undergoing Dacryocystorhinostomy Surgery
The aim is to investigate the anxiolytic effect, and hemodynamic stability of using virtual reality immersion in adult patients undergoing Dacryocystorhinostomy (DCR) operation under general anesthesia and to compare its effect…
- Conditions
- Anxiolytic Effect, Virtual Reality Immersion, Midazolam, Premedication
- Trial name
- NCT07050095
- Testing
- Virtual Reality Group, Midazolam Group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Anesthesia
Premedication on Sevoflurane Induction
The goal of this study was to investigate the effects of fentanyl-midazolam premedication during sevoflurane induction pertaining to time to loss of eyelash reflex (LER), time and conditions of insertion of proseal laryngeal mask…
- Trial name
- NCT00723164
- Testing
- Fentanyl and Midazolam, NaCl
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Maisonneuve-Rosemont Hospital
MRI, Pediatric Sedation
Intranasal Dexmedetomidine Versus Oral Midazolam as Premedication for Propofol Sedation in Pediatric Patients Undergoing Magnetic Resonance Imaging
A magnetic resonance imaging (MRI) examination usually takes 30 to 45 minutes and requires the patient to remain perfectly still during the entire acquisition process to ensure quality.
- Conditions
- MRI, Pediatric Sedation, Midazolam, Dexmedetomidine
- Trial name
- NCT05192629
- Testing
- Dexmedetomidine, Midazolam
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- Brugmann University Hospital
Preoperative Anxiety
Impact of Premedication on Anxiety
IMPACT aims to evaluate the clinical routine practice of premedication in German hospitals and to estimate the influence of premedication on anxiety reduction.
- Trial name
- Impact (NCT04103723)
- Testing
- Preoperative premedication
- Where
- Germany
- Volunteers
- 4,000 people
- Sponsor
- RWTH Aachen University
Preoperative Anxiety Experienced by the Pediatric Patient, Preoperative Anxiety
Comparing Two Doses of Midazolam With Added Dexmedetomidine for Kids Before Surgery
The goal of this randomized controlled trial is to investigate if adding intranasal dexmedetomidine to two different doses of intranasal midazolam provides effective sedation with fewer side effects in pediatric patients aged 1…
- Trial name
- NCT06979791
- Testing
- Dexmedetomidine + Midazolam 0.4 mg/kg, Dexmedetomidine + Midazolam 0.2 mg/kg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Anesthesia
Effect of Oral Dexmedetomidine, Ketamine, Or Midazolam as Preioperative Medications.
Anxiety preceding surgery results in hemodynamic instability, metabolic side effects, increased post-operative pain, and agitation during emergence.
- Trial name
- NCT05874245
- Testing
- oral Dexmedetomidine, oral ketamine, oral Midazolam
- Where
- Egypt
- Volunteers
- 222 people
- Sponsor
- Menoufia University
Pre Operative Sedation, Mask Acceptance
Effect of Dexmedetomidine Versus Midazolam Versus a Combination of the Two as a Premedication for Children Undergoing Bilateral Myringotomy Tube Insertion
Following an obtained written consent, a child presenting for ear tube surgery will be randomized into one of three groups for receiving a premedication.
- Conditions
- Pre Operative Sedation, Mask Acceptance, Post Operative Delerium
- Trial name
- NCT02134327
- Testing
- Combination of Dexmedetomidine with Midazolam
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Dental Surgeries
Comparison of Nebulized Fentanyl, Midazolam and Dexmedetomidine as a Premedication in Pediatric Dental Surgeries
The preoperative time can be traumatic for young children undergoing surgery. Pediatric anesthesiologists act strongly to decrease distress for children in the operating room (OR) and to provide a smooth induction of anesthesia.
- Trial name
- NCT04226885
- Testing
- fentanyl, midazolam, dexmedetomidine
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Pediatric, Anesthesia
Comparison of Oral Dexmedetomidine, Ketamine Versus Midazolam for Premedication in Children Undergoing Injuinal Surgeries
The aim of this study is to compare between oral dexmedetomidine, Ketamine or midazolam for premedication in children undergoing inguinal hernia surgeries.
- Trial name
- CODKMPCIS (NCT06879496)
- Testing
- Oral ketamin, Oral Midazolam, Oral dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tanta University
In Vitro Fertilization, Stress
What Amount of Stress is Enough for a Successful Conception?
The aim of the study is to determine whether premedication with midazolam before oocyte aspiration in IVF procedures affects the amount of (oxidative) stress in women undergoing IVF and whether stress is also transmitted to the…
- Conditions
- In Vitro Fertilization, Stress, Midazolam Adverse Reaction, Stress, Emotional
- Trial name
- NCT04160611
- Testing
- Midazolam 7.5mg
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- University Hospital Sestre Milosrdnice
Separation, Family, Separation Anxiety
Use Of Midazolam In Premedication Of Pediatric Patients
: The aim of the study is to compare the effect of intranasal and oral midazolam administered for premedication to children of preschool age on hemodynamic parameters, sedation and separation from parents.
- Trial name
- NCT07021755
- Testing
- midazolam
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Parental/Caregiver Anxiety, Child's Anxiety
A Comparison of Midazolam and Zolpidem as Oral Premedication in Children
The purpose of this investigator-initiated study is to compare the efficacy of oral midazolam and zolpidem for preoperative sedation, anxiety of patient, and caregiver anxiety at the time of separation, and ease of mask…
- Trial name
- PedsPreMed (NCT02096900)
- Testing
- zolpidem, Midazolam
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Loma Linda University