Clinical trials: Mild Stroke
Ischemic Stroke, Intracerebral Hemorrhage
Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
The overall goal of the DISCOVERY study is to better understand what factors contribute to changes in cognitive (i.e., thinking and memory) abilities in patients who experienced a stroke.
- Conditions
- Ischemic Stroke, Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Dementia, Vascular
- Trial name
- DISCOVERY (NCT04916210)
- Where
- 31 sites in United States
- Volunteers
- 8,000 people
- Sponsor
- Massachusetts General Hospital
Mild Cognitive Impairment, Stroke
Evolving Methods of Hybrid Exercise-cognition Approach to Promote Health-related Conditions for the Elderly With MCI
The aim of the study is to determine: (1) the effects of combined physical exercise and cognitive training versus exercise or cognitive training alone on cognition, physical function, daily function, quality of life and social…
- Trial name
- NCT03927586
- Testing
- cognitive training, physical exercise training
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Acute Ischemic Stroke, Stroke, Acute
Xingnaojing for Mild-to-severe Acute Ischemic Stroke
The main purpose of this trial is to determine whether Xingnaojing, intravenously administered within 24 hours of symptom onset, improves the daily living ability of acute ischemic stroke at 90 days.
- Conditions
- Acute Ischemic Stroke, Stroke, Acute, Stroke, Ischemic
- Trial name
- XMAS-2 (NCT04150835)
- Testing
- Xingnaojing injection, Standard care
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Dongzhimen Hospital, Beijing
Atrial Fibrillation
Dabigatran Etexilate for Stroke Prevention in Patients With Atrial Fibrillation and Mild to Moderate Renal Impairment
Non-interventional, observational study of physicians' use of Dabigatran etexilate for stroke prevention in patients with atrial fibrillation and mild to moderate renal impairment
- Trial name
- NCT01721837
- Where
- 1,616 sites in Germany
- Volunteers
- 4,340 people
- Sponsor
- Boehringer Ingelheim
Acute Ischemic Stroke, Mild Neurocognitive Disorder
Endovascular Therapy Versus Best Medical Treatment for Acute Large Vessel Occlusion Stroke With Low NIHSS
Patients presenting with mild symptoms of acute ischemic stroke are common and account for approximately half of all acute ischemic stroke. About 30% of patients with minor stroke have a 90-day functional disability.
- Conditions
- Acute Ischemic Stroke, Mild Neurocognitive Disorder, Thrombectomy
- Trial name
- NCT06143488
- Testing
- Endovascular therapy, Best medical management
- Where
- China
- Volunteers
- 264 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Stroke, Mild Cognitive Impairment
Investigating Neurocognitive, Motor and Biological Effects of MindLenses Professional in Neurological Diseases
This study aims to explore the effects of the treatment with MindLenses Professional device on cognitive and motor performances,as well as on the levels of a neurotrophic factor implied in brain plasticity, that is the brain…
- Trial name
- MindLensesN (NCT05826626)
- Testing
- MindLenses Professional, Conventional rehabilitation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Acute Ischemic Stroke
Caffeinol Hypothermia Protocol
Caffeinol is a combination of caffeine and alcohol. The amount given is about the same as 1-2 glasses of wine and 3-4 cups of coffee. The patient receives a one time dose given over two hour while being cooled to 34.5 C.
- Trial name
- NCT00299416
- Testing
- Caffeinol, hypothermia
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center, Houston
Stroke, Ischemic, Mild Cognitive Impairment
Dapagliflozin Effect in Cognitive Impairment in Stroke Trial
Background: Dementia is an international public health problem, affecting approximately 50,000,000 people worldwide in 2018 and will triple by 2050; furthermore, reaching an approximate cost of 4 billion dollars.
- Conditions
- Stroke, Ischemic, Mild Cognitive Impairment, Dementia, Vascular, Metabolic Syndrome
- Trial name
- DECIST (NCT05565976)
- Testing
- Dapagliflozin 10mg Tab, Statins (Cardiovascular Agents), Platelet Antiaggregant
- Where
- Mexico
- Volunteers
- 270 people
- Sponsor
- Jaime Daniel Mondragon
Traumatic Brain Injury, Stroke
Internet Delivered Cognitive Rehabilitation for Mild Cognitive Impairments
Acquired brain injury and neurological disorders cause cognitive deficits, which in turn cause reduced participation in everyday life.
- Conditions
- Traumatic Brain Injury, Stroke, Multiple Sclerosis, Parkinsons Disease (PD)
- Trial name
- eRehabCog (NCT06973018)
- Testing
- eRehabCog, CogMed QM
- Where
- Sweden
- Volunteers
- 64 people
- Sponsor
- Aniko Bartfai
Neuro-Degenerative Disease
Synaptic Density, Tau and Multiparametric PET-MR in Brain Trauma, Stroke and Mild Cognitive or Behavioral Impairment.
Alzheimer's disease, stroke and TBI are frequently observed brain disorders, causing significant morbidity. For none of these disorders, there are in vivo diagnostic biomarkers available that allow determination of disease…
- Trial name
- NCT03514524
- Testing
- PET-MR imaging
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Stroke, Action Speed
Diagnostic and Prognostic Value of New Quick Tests of Action Slowing in Stroke and in Cognitive Neurodegenerative Disease
A large series of recent studies have documented the frequency of the slowing of the action in brain diseases, especially vascular and neurodegenerative diseases.
- Conditions
- Stroke, Action Speed, Dementia Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- QTOAS (NCT05785156)
- Testing
- quick tests
- Where
- France
- Volunteers
- 129 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
CVA (Cerebrovascular Accident), Stroke
Constraint-Induced Movement Therapy Plus Sensory Components After Stroke
Constraint-Induced Movement Therapy or CI Therapy is a form of treatment that systematically employs the application of selected behavioral techniques delivered in intensive treatment over consecutive day with the following…
- Conditions
- CVA (Cerebrovascular Accident), Stroke, Upper Extremity Paresis
- Trial name
- NCT05515237
- Testing
- Grade 2-5 CI Therapy + Sensory Components
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Alabama at Birmingham
Brain Tumors, Epilepsy
Quality Improvement and Practice Based Research in Neurology Using the EMR
The investigators will conduct at NorthShore University HealthSystem pragmatic trials using the EMR for 10 common neurological disorders.
- Conditions
- Brain Tumors, Epilepsy, Migraine, Mild Cognitive Impairment
- Trial name
- NCT02670161
- Testing
- Listed for each disorder below, up to three drugs per disorder (too many characters to list in this field; see Intervention Description)
- Where
- United States
- Volunteers
- 3,300 people
- Sponsor
- Endeavor Health
AIS
NBP in Adult Patients With Acute Ischemic Stroke (AIS)
This is a Phase 2 multicenter, randomized, double-blind, placebo-controlled, add-on to standard of care study of NBP softgel capsules for the treatment of mild to moderate AIS in adults.
- Trial name
- NCT02905565
- Testing
- NBP Softgel Capsules
- Where
- 21 sites in United States
- Volunteers
- 177 people
- Sponsor
- CSPC-NBP Pharmaceutical Co., Ltd.
Ischemic Stroke, Hypothermia
Reperfusion With Cooling in Cerebral Acute Ischemia II
The purpose of this study is to determine whether reducing a patients body temperature (mild hypothermia of 33 degrees Centigrade) will significantly reduce the risk of brain injury (notably reperfusion injury and hemorrhagic…
- Trial name
- ReCCLAIM II (NCT01728649)
- Testing
- Mild Hypothermia
- Where
- United States
- Sponsor
- WellStar Health System
Comorbidities and Coexisting Conditions, Alzheimer Disease
An Integrated Solution for Sustainable Care for Multimorbid Elderly Patients With Dementia
The CAREPATH will conduct Technical Validation and Usability (TVU) study by involving ≥ 45 target end users (16 patients with MCI or mild dementia with their informal caregivers and 16 healthcare professionals from various…
- Conditions
- Comorbidities and Coexisting Conditions, Alzheimer Disease, Dementia, Malnutrition
- Trial name
- CAREPATH (NCT05104593)
- Testing
- Intervention tested (CAREPATH)
- Where
- Spain
- Volunteers
- 204 people
- Sponsor
- Complejo Hospitalario Universitario de Albacete
Stroke, Chronic Disease
Clinical Effectiveness of Self-Management Education Post-Mild Stroke
Individuals who have a mild stroke have a 44% risk of dying from a second stroke within 10 years which is in large part due to the cyclical relationship of chronic disease, poor health, and mild stroke which has gone largely…
- Trial name
- NCT01770184
- Testing
- Chronic Disease Self-Management Program (CDSMP)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Washington University School of Medicine
Cognitive Impairment
Compensatory and Restorative Rehabilitation Techniques in Stroke
The aim of this randomized controlled trial is to find the combined effects of restorative and compensatory cognitive rehabilitation techniques in mild cognitive impairment after stroke.
- Trial name
- NCT06325085
- Testing
- compensatory and restorative rehabilitation techniques, Traditional cognitive rehabilitation training
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Parkinson Disease, Mild Cognitive Impairment
Financial Abilities in Neurological Diseases. Development of a Telerehabilitation Program: FINAGE
Financial Abilities (FA) are a set of capacities that allow a person to independently manage her/his financial affairs in a manner consistent with personal self-interests and values.
- Conditions
- Parkinson Disease, Mild Cognitive Impairment, Stroke
- Trial name
- FINAGE (NCT05826548)
- Testing
- Telerehabilitation group, Conventioanl treatment group
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
ATRIAL APPENDAGE CLOSURE for ATRIAL FIBRILLATION, PFA Ablation and LAAC Procedures
Left Atrial Appendage Closure With Versus Without Pulsed Field Ablation in Atrial Fibrillation Patients With Mild Symptoms and High Stroke Risk
This study is a prospective, multicenter, single-blinded, randomized controlled trial to investigate whether concomitant left atrial appendage closure (LAAC) and pulsed field ablation (PFA) is more effective than LAAC alone in…
- Trial name
- REVERSE-OPTION (NCT07453940)
- Testing
- LAAC plus PFA for persistent AF with high risk of stroke, LAAC for persistent AF with high risk of stroke
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sir Run Run Shaw Hospital