Clinical trials: Moderately Obese
Overweight and Obesity
Effect of Exercise Programme on Gut Microbiota, CVD Risk Factors and Appetite Regulation in Overweight Women
Evidence suggests that gut microbiota contributes to the development of atherosclerosis and therefore CVDs. Exercise has been extensively reported to be protective against CVDs due to modification of body fatness, metabolic risk…
- Trial name
- NCT03344133
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Bariatric Surgery Candidate
Influence of a Moderate Physical Exercise Program in Health of Patients Underwent Bariatric Surgery in Talca City, Chile
Obesity is a multifactorial disorder resulting from multivariate etiopathogenic factors. The current lifestyle, causes a gradual increase in weight both in the adult population and in the child population.
- Trial name
- NCT03159312
- Testing
- Physical activity based on a moderate exercise program
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Knee Osteoarthriis and Oxidative Stress
Do Obese Patients With Primary Knee Osteoarthritis Benefit From a Single Bout of Moderate Intensity Aerobic Exercise?
Background: Obesity and degenerative joint disease are typically concomitant . Each are in the course of aerobic focus and excited inflammatory response.
- Trial name
- NCT03927339
- Testing
- pre and post excercise group
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Obstructive Sleep Apnea
Effect of a Very Low Calorie and Low Calorie Diet on Moderate to Severe Obstructive Sleep Apnea in Obese Adults
The purpose of this study is to test the effectiveness of two different weight loss diets on obstructive sleep apnea (OSA) severity.
- Trial name
- NCT02251574
- Testing
- Low Calorie Diet, Very Low Calorie Diet, Standard Care
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Pulmonary Disease, Chronic Obstructive
A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of GSK2256294 in Healthy Volunteers, and Single and Repeat Doses of GSK2256294 in Adult Male Moderately Obese Smokers
This study is the First Time in Human Study for GSK2256294 and will evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single and repeat oral doses of GSK2256294 administered to healthy male…
- Trial name
- NCT01762774
- Testing
- GSK2256294
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Hypercholesterolemia
Influence of Simvastatin on Apolipoprotein B-100 (apoB-100) Secretion
3-Hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins) decrease apolipoprotein B-100-containing lipoproteins by increasing their fractional catabolic rates through low-density lipoproteins (LDL) receptor-mediated…
- Trial name
- SVS (NCT00905541)
- Testing
- simvastatin
- Where
- Germany
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Healthy, no Evidence of Disease, Obesity
Study of a Smart Growth Community's Effect on Prevention of Obesity in Middle-, Moderately Low- and Low-Income Families
RATIONALE: Overweight and obesity have been associated with multiple types of disease, including cancer. Living in a smart growth community may encourage behaviors that would reduce the risk of obesity.
- Conditions
- Healthy, no Evidence of Disease, Obesity, Weight Changes
- Trial name
- NCT00986011
- Testing
- questionnaire administration, study of socioeconomic and demographic variables, survey administration
- Where
- United States
- Volunteers
- 780 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Obesity
Food Supplement Effect on Overweight or Moderate Obesity
The aim of this study is to assess the effect of a food supplement containing extracts of carrot and rose hip seeds on the weight of volunteers with overweight or moderate obesity.
- Trial name
- PHYTOENIX (NCT05178667)
- Testing
- High dose, Low dose, Maltodextrin
- Where
- 2 sites in France
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
Gut Microbiota, Adiposity
Effect of a Synbiotic on the Gut Microbiota and Adiposity-related Markers in Healthy Overweight Subjects
The purpose of this study is to investigate the effects of a synbiotic (ProSynbiotic) on the gut microbiota composition, body composition and adiposity-related genes and metabolic markers in healthy overweight adult subjects.
- Trial name
- NCT02151825
- Testing
- Synbiotic
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Texas State University, San Marcos
Hypertension, Diabetes Mellitus
The Study of CCTM and Common Diseases
This study aimed to explore the associations between constitutions of traditional Chinese medicine (TCM) and common disease (CD).
- Conditions
- Hypertension, Diabetes Mellitus, Chronic Obstructive Pulmonary Disease Moderate, Coronary Artery Disease
- Trial name
- NCT02998944
- Volunteers
- 3,748 people, healthy volunteers welcome
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Obesity
Outcomes of Circuit Training and Low Carbohydrates Diet in the Young Obese Male in KSA
Obesity is one of the common public problems that its prevalence increase incredibly in the last three decades in KSA. Thirty obese males aged 20 to 39 years will participate in the study.
- Trial name
- NCT04794309
- Testing
- Circuit training exercise, Healthy high Fiber diet
- Where
- Saudi Arabia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Majmaah University
Obesity
Effect of High-intensity Intermittent Sprinting on Appetite Control on Obese Volunteers
Several studies have shown that high intensity intermittent sprints (HIIS) are more effective than moderate intensity continuous cycling (MICC) in reducing fat mass and improving insulin resistance in normal weight individuals.
- Trial name
- NCT01143363
- Testing
- resting - control, Moderate intensity exercise, High intensity intermittent training
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Appetite and Hunger, Suppression, Blood Glucose, Postprandial
Evaluation of Subjective Ratings of Appetite and Glucoregulation of a Low Calorie Diet Supplemented With a High Viscosity Polysaccharide (PolyGlycopleX - PGX)
The objective of the study is to compare subjective appetite ratings and after-meal and 24 hour blood glucose levels within overweight and obese female subjects consuming either a standardized 3 day low calorie diet supplemented…
- Trial name
- NCT01108328
- Testing
- PolyGlycopleX (PGX)
- Where
- 2 sites in Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Canadian Center for Functional Medicine
Physical Activity, Social Identity
"We Are an Active Family": Promoting Child Physical Activity Through Social Identity Formation in the Family System
The purpose of our study is to explore the effectiveness of physical activity (PA) identity formation in the family system as a promotor of long-term PA.
- Trial name
- NCT05794789
- Testing
- Social Identity
- Where
- 2 sites in Canada
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Victoria
Overweight and Obesity, Chronic Disease
Influence of Genetic and Physiological in Weight Loss
The study focuses on the influence of polymorphism in the FTO genes rs9939609 and PPARᵧ Pro12Ala, oxidative stress and systemic inflammation on changes in body composition and rest metabolism induced by HIIT and continuous…
- Trial name
- NCT03568773
- Testing
- High-intensity interval training, Aerobic exercise moderate intensity, Control Group
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Metabolism, Physical Fitness
High Intensity Interval Versus Continuous Moderate Intensity Training: Maximizing the Benefits of Exercise in Overweight Adolescents
6-week, single site, two parallel arm, randomized, controlled trial comparing the effectiveness of a High Intensity Interval Training (HIIT) versus a continuous Moderate Intensity Training (MIT) program on cardiovascular and…
- Trial name
- HIIT-MAX (NCT01935323)
- Testing
- High Intensity Interval Training, Moderate Intensity Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Breast Milk Collection, Overweight and Obesity
Acute Effects of Endurance Exercise on Breast Milk Composition in Women With Overweight/Obesity
The investigators will determine the acute effect of exercise on breastmilk composition. Participants will come in to the lab on three different days, out of which they will exercise on two of these days and rest in the lab on…
- Trial name
- YT (NCT05745922)
- Testing
- Moderate intensity exercise, High intensity exercise
- Where
- Norway
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Hypercholesterolemia, Cardiovascular Risk Factor
Effect of Totum-070 on Lipid Metabolism in Moderate Hypercholesterolemic Subjects
This clinical study aims to assess the efficacy of TOTUM-070, a mix of 5 plant extracts, on lipid metabolism in moderate hypercholesterolemic subjects.
- Conditions
- Hypercholesterolemia, Cardiovascular Risk Factor, Dyslipidemias, Overweight and Obesity
- Trial name
- HEART (NCT04760951)
- Testing
- TOTUM-070
- Where
- 4 sites in France, Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Valbiotis
Overweight, Obesity
Move and Moderate in Balance
H1: The increase in body mass index between baseline and two year follow-up among intervention worksites will be lower than that among control worksites, such that the differential change will be negative on average.
- Conditions
- Overweight, Obesity, Sedentary
- Trial name
- MOVE'M (NCT00715130)
- Testing
- Energy Balance
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Chronic Obstructive Pulmonary Disease Moderate, Obesity
Aerosol Therapy in Obese COPD Patients.
This study has the objective to clarify the factors that directly influence the effectiveness of inhaled drug deposition in obese patients with chronic obstructive pulmonary disease (COPD) and suggest the use of High Flow Nasal…
- Trial name
- NCT03031093
- Testing
- inhalation protocol, High Flow Nasal Cannula
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte