Clinical trials: Modification
White Spot Lesion
Effectiveness of Resin-Modified Glass Ionomer Varnish in Preventing White Spot Lesions in Fixed Appliance Orthodontia
This is a prospective study to determine the effects of resin-modified glass ionomer (RMGI) on the prevention of white spot lesion (WSL) development during fixed appliance orthodontic treatment.
- Trial name
- NCT03711097
- Testing
- Vanish XT Dental Varnish
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Climate Change, Health Behavior
Promoting Environmental Responsibility Toward Climate Change
This study was designed to evaluate the effectiveness of a climate change environmental responsibility development program for middle school students on their environmental responsibility, environmental attitudes, and…
- Conditions
- Climate Change, Health Behavior, Environmental Awareness and Sensitivity
- Trial name
- NCT07429513
- Testing
- Environmental Responsibility Program, Brochure and standard curriculum
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Cardiovascular Diseases, Coronary Artery Disease
Using the Visualization for Lifestyle Change in Patients At Risk of Cardiovascular Diseases
In the framework of PhD research, the investigators will present a visualization of estimation of CVDs risk and the possibility of monitoring blood glucose levels in real-time.
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Heart Diseases, Coronary Heart Disease
- Trial name
- NCT06226948
- Testing
- CGM, Visualization
- Where
- Slovenia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Maribor
All-cause Mortality, Cardiovascular Disease
The Global Cardiovascular Risk Consortium
The Global Cardiovascular Risk Consortium (GCVRC) brings together harmonized individual-level data from currently more than 2 million (anticipated: approximately 3 million) individuals across 133 cohorts, 40 countries, and 6…
- Trial name
- NCT05466825
- Where
- Germany
- Volunteers
- 3,000,000 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Healthy Infants
Changing Chat: Diaper Tips to Improve Language Development
This randomized trial has two sets of diapers-- a normal one and one that has tips for how to talk to and engage your toddler. The investigators are hoping that the intervention improves language development.
- Trial name
- NCT01594840
- Testing
- Changing chat
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Nutrient Intake, Nutrient Intake Inadequacy
Effects of Dietary Supplements on Nail and Hair Health
This is a research study conducted by Standard Process, Inc. and the University of North Carolina and Chapel Hill Nutrition Research Institute, which aims to evaluate the effectiveness of nutritional supplementation in improving…
- Trial name
- NCT07373574
- Testing
- Immune Health (Congaplex), Active Control (Gastro-Fiber), Immune Health (Immuplex)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Standard Process Inc.
Child Obesity
Mixed Methods Feasibility Study of an App for Childhood Obesity Prevention and Management
This evaluation evaluated Health Education England's NoObesity digital health app's usability and acceptability to undertake activities improving families' diet, physical activity and weight.
- Trial name
- NCT05261555
- Testing
- NoObesity app
- Where
- United Kingdom
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- University of Plymouth
Cancer
Slimming Myokines, Cancers,Nutritional and Psychology Support
With the project investigators propose, investigators aim to find answers to the following questions: The fact that irisin and atropine are slimming the proteins that cause an increase in weight loss, and the excessive wasting…
- Trial name
- NCT05278078
- Testing
- psychological support, nutritional education, psychological support and nutritional education
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Ordu University
Hazardous Drinking, Harmful Drinking
Testing the Efficacy of an Online Alcohol Intervention in a Workplace Setting
The purpose of this study is to test - in a workplace setting - if an online multi-session alcohol intervention improves treatment effect over and above a single session screening with feedback.
- Trial name
- NCT01931618
- Testing
- Online screening and feedback, Online booklet., Online multi session follow-up
- Where
- Norway
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Healthy
Corneal Endothelial Cell Density Changes In Healthy Subjects, When Administered ISV-403 for 5 Days
The objective of this study is to evaluate the effect on corneal endothelial cell density changes when ISV-403 is administered for five (5) days compared to no drug treatment, in healthy subjects.
- Trial name
- NCT01120418
- Testing
- Besifloxacin Ophthalmic Suspension 0.6%
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Gestational Diabetes Mellitus
Weight Changes During and After Pregnancy in Women With Gestational Diabetes
Gestational diabetes mellitus (GDM) is associated with short-term and long-term complications for infants and mothers. The management of GDM during pregnancy focuses on reducing risks to the infant associated with hyperglycemia.
- Trial name
- NCT02388958
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Type 2 Diabetes Mellitus
Type 2 Diabetes Controlled Eating Experiment
A short-term feeding study in type 2 diabetics manipulating the fat and caloric values of meals to assess both compensation and glucose control, both covertly and overtly.
- Trial name
- NCT00198926
- Testing
- covert v overt nutrition labeling, varying meal nutrition manipulation
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Inflammatory Bowel Disease
Study to Observe the Change in Microbiome in Human Derived Sample and the Relation With Clinical Response Before and After the Anti-TNF Treatment in IBD Patients
This study will be conducted to observe the difference in microbiome composition between healthy participants and inflammatory bowel disease (IBD) participants with no anti-tumor necrosis factor (anti-TNF) treatment.
- Trial name
- ETERNITY (NCT03264690)
- Where
- 3 sites in South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Eisai Korea Inc.
Healthy Participants, Healthy Subjects
Study to Learn How Different Forms of The Study Medicine Called Danuglipron Are Taken up Into the Blood In Healthy Adults
The purpose of the study is to learn how different forms of a study medication called danuglipron are taken into the blood in healthy adults, following single dose administration.
- Trial name
- NCT06153758
- Testing
- Danuglipron
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Pfizer
Sterility, Reproductive
Age-dependent Changes in the Responsiveness of Hypothalamic Pituitary Gonadal Axis in Men
The present study was designed to assess the responsiveness of the hypothalamic pituitary gonadal axis to kisspeptin administration with increasing age in men.
- Trial name
- NCT03315325
- Testing
- Human kisspeptin-10 (metastin 45-54)
- Where
- Pakistan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Quaid-e-Azam University
Anorexia Nervosa
Investigation of Psycho-Physiological Parameters in Adolescent Inpatients With Anorexia Nervosa
A study to assess changes in mental and physical symptoms in adolescent inpatients with anorexia nervosa, a severe eating disorder.
- Trial name
- NCT04083989
- Testing
- Integrative medicine-based multimodal treatment
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Hypoxia
Effects of Normobaric Hypoxia Exercise Program on Bone Turnover Markers and Metabolism in Premenopausal Women
The impact of a proprietary training program in normobaric hypoxia on changes in bone turnover markers as well as carbohydrate and lipid metabolism in premenopausal women falls within the realm of physical culture for an active…
- Trial name
- NCT06226168
- Testing
- exercise and environmental conditions
- Where
- 2 sites in Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University School of Physical Education, Krakow, Poland
Celiac Disease, Malabsorption Syndromes
Immune Responses to Gluten
This is a study of immune responses after eating gluten powder in people with celiac disease and healthy controls.
- Conditions
- Celiac Disease, Malabsorption Syndromes, Digestive System Disease, Intestinal Disease
- Trial name
- NCT05209568
- Testing
- Gluten Powder
- Where
- 2 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Oral Health Care, Oral Health Behavior Change
Improving Dental Care for Patients With Head and Neck Tumors
This prospective survey study investigates knowledge, attitudes, experiences, and practices related to dental care in patients with head and neck cancer among affected patients and dentists.
- Conditions
- Oral Health Care, Oral Health Behavior Change, Head & Neck Cancer, Dentist's Role
- Trial name
- OncoDent (NCT07328347)
- Testing
- Educational material,
- Where
- Germany
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Health, Subjective
Thermographic Analysis of Hemodynamics Changes Through & Following Wingate Test
Remote sensing and measurements of hemodynamic changes in blood flow for Wingate Anaerobic test using a novel image processing algorithm.
- Trial name
- NCT05361876
- Where
- Israel
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
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