Clinical trials: Modification
Covid19, Fear
Correlation Fear of COVID-19 & Dental Treatment Anxiety
Purpose: COVID-19 Pandemic has created fears, anxiety and worries among general population. COVID-19 airborne transmission is possible under circumstances in which procedures generate aerosols.
- Conditions
- Covid19, Fear, Dental Anxiety
- Trial name
- NCT04497818
- Testing
- Cross Sectional study using scientifically validated psychometric Scales
- Where
- Saudi Arabia
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Qassim University
Pregnancy Outcome, Gestational Weight Gain
The Effect of Individualized Exercise Guidance on Pregnancy Outcome
A single center, randomized controlled trial was conducted to investigate whether individualized exercise guidance was more effective in improving pregnancy outcomes in normal pregnant women.
- Conditions
- Pregnancy Outcome, Gestational Weight Gain, Mediation, Macrosomia, Fetal
- Trial name
- NCT05760768
- Testing
- Individualized exercise guidance
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Body Temperature Changes
Follow Fever to Decide
Body temperature is one of the markers of biological rhythms. The precise determination of the functioning of the biological clock for an individual is essential to understanding his physiological state at a given time.
- Trial name
- NCT04311268
- Testing
- F2D armband
- Where
- France
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Slb Pharma
Obesity
Dyadic Approach To Active Living and Eating Healthy: The DATE Study
The purpose of the DATE study is to evaluate the feasibility and acceptability and a preliminary evaluation of the efficacy of a dyadic health behaviour change intervention to improve healthy eating, physical activity, and dyadic…
- Trial name
- DATE (NCT04660968)
- Testing
- Dyadic health behaviour change intervention, Dyadic nutrition counselling intervention
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Concordia University, Montreal
Change in Fasting Plasma LDL-cholesterol Concentration After the Consumption of Quinoa
Effects of Quinoa Consumption on Markers of Cardiovascular Risk and Gastrointestinal Health
Quinoa is possible alternative to wheat, corn and rice due to its high nutritional value and possible properties against cardiovascular diseases and for improving gut health.
- Trial name
- NCT03036618
- Testing
- Quinoa, Wheat
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Sleep
An Interactive School Sleep Education Program
The aim of this study is to improve sleep behavior in secondary school students, through the use of an educational program specifically designed for this purpose.
- Trial name
- NCT03620240
- Testing
- Sleep Education
- Where
- Singapore
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Morbid Obesity, Weight Loss
Endoscopic Gastric Plication for Weight Loss in Morbidly Obese Patients Prior to Incisional Hernia Repair
Incisional hernias occur in nearly 20% of all laparotomy incisions accounting for almost 400,000 ventral hernia repairs annually in the United States.
- Conditions
- Morbid Obesity, Weight Loss, Complex Incisional Hernias
- Trial name
- NCT02078934
- Testing
- Endoscopic Gastric Plication
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Overweight, Obesity
Adolescents Committed to Nutrition and Physical Activity
Community based participatory research principles will be used to create, implement and evaluate a culturally relevant and age-appropriate obesity intervention for adolescents who are overweight or obese.
- Conditions
- Overweight, Obesity, Insulin Resistance
- Trial name
- ACTION (NCT00841334)
- Testing
- ACTION, Usual care
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Neuromuscular Function, Muscle Activation
Mechanistic Drivers of Acute PAPE Responsiveness: Muscle Architecture, Contractile Kinetics, and Excitability in a Randomized Controlled Trial
The goal of this study is to find out if one short set of heavy half-squats can help football players jump higher right away-and to understand what happens inside their muscles and nerves to make that boost happen.
- Conditions
- Neuromuscular Function, Muscle Activation, Postactivation Potentiation, Ultrasonography
- Trial name
- NCT06982937
- Testing
- High-Intensity Half-Squat, Treadmill running
- Where
- Poland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Healthy Participants
A Study to Investigate the Pharmacokinetic Profile of ALXN2050 Modified Release Prototype Formulations and Immediate Release Reference Tablet in Healthy Adult Participants
The primary objectives of this study are to investigate the relative bioavailability and PK (Pharmacokinetic) profile of 2 ALXN2050 MR (Modified Release) formulations in comparison with the IR (Immediate Release) formulation.
- Trial name
- NCT05780645
- Testing
- ALXN2050 MR Prototype Tablet, ALXN2050 Immediate Release (IR) Tablet, ALXN2050 MR Prototype Mini-Tablet
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alexion Pharmaceuticals, Inc.
Muscle Mass
Strength Training Response of Muscle in GLP-1 Users
GLP-1 medication is being prescribed for weight loss. However, GLP-1 medication may adversely affect muscle mass and muscle function.
- Trial name
- STRONG-GLP (NCT07104539)
- Testing
- Strength Training, Wait first, then strength training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Hypothyroidism
Hypothyroidism Treated With Calcitonin
Some people with hypothyroidism have persistent symptoms despite adequate treatment with thyroid hormones. We are testing whether giving calcitonin to such people will improve their quality of life.
- Trial name
- NCT03342001
- Testing
- Calcitonin
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Jaw, Edentulous, Edentulism, Complete
Tri-Lobe vs. Hexagonal Connections in Immediately Loaded Mandibular Overdentures
Objective: Compare changes in crestal bone height and peri-implant bone density using cone-beam computed tomography (CBCT) at baseline, 6 months, and 12 months post-placement.
- Conditions
- Jaw, Edentulous, Edentulism, Complete, Peri-implant Bone Loss
- Trial name
- NCT07824219
- Testing
- ReActive Implant System (Internal Tri-Lobe Platform), Legacy II Implant System (Internal Hexagonal Platform)
- Where
- United Arab Emirates
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Post Liver Transplantation Weight Gain, Post Liver Transplantation Obesity
Effect of Dietary and Life Style Modification on Post Liver Transplant Obesity
This study is to assess value of providing classes about dietary and life style modifications to decrease or prevent weight gain, less occurrence or better control of weight gain associated disorders such as high blood sugar…
- Conditions
- Post Liver Transplantation Weight Gain, Post Liver Transplantation Obesity, Nonalcoholic Steatohepatitis
- Trial name
- NCT00878592
- Testing
- Dietary and life style modification
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Motor Skills Disorders
Taekwondo for Children With Developmental Coordination Disorder
Objectives: To evaluate the effects of a novel adapted Taekwondo (TKD) training programme on skeletal development and motor proficiency in pre-pubertal children with developmental coordination disorder (DCD).
- Trial name
- NCT02635711
- Testing
- Adapted Taekwondo training, Control
- Where
- Hong Kong
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Nutrition, Healthy
Effect of Transtheoretical Model Based Nutrition Education on Sustainable Nutrition Behavior in Adolescents
The aim of this intervention study is to evaluate the effect of sustainable nutrition education based on the Transtheoretical Model (TTM) on adolescent behavior.
- Trial name
- NCT06583499
- Testing
- Sustainable nutrition education based on the transtheoretical model
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Obesity, Insulin Resistance
Study of Time-restricted Eating on Weight Loss.
This is a randomized controlled trial studying the effects of time-restricted eating (TRE) on weight loss in obese humans. Obesity is the number one risk factor for type 2 Diabetes Mellitus (T2DM), and numerous studies…
- Trial name
- TREAT (NCT03393195)
- Testing
- Time-restricted Eating plan, Consistent Meal timing plan
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Suicide, Aggression
Social Ecology and the Prevention of Suicide and Aggression in African American Youth
The purpose of this study is to examine the efficacy of a culturally-grounded, school-based suicide and aggression preventive intervention for African American adolescents (Adapted-Coping with Stress Course [A-CWS]).
- Trial name
- NCT03954457
- Testing
- A-CWS, Standard Care Control
- Where
- United States
- Volunteers
- 939 people, healthy volunteers welcome
- Sponsor
- DePaul University
Obesity
Low Intensity Weight Loss for Young Adults
This is a 3-arm randomized controlled trial to test the efficacy of three novel motivational approaches to weight loss with 18-25 year olds.
- Trial name
- REACH (NCT02736981)
- Testing
- Behavioral Weight Loss (BWL), BWL + Autonomous Motivation, BWL + Extrinsic Motivation
- Where
- United States
- Volunteers
- 382 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Ulcerative Colitis
Study of the Effect of Vedolizumab on Intestinal Microecological Changes and Its Efficacy in the Treatment of Ulcerative Colitis
Inflammatory bowel disease is a group of chronic, non-specific inflammatory diseases of the intestinal tract whose etiology has not yet been fully elucidated, including ulcerative colitis and Crohn's disease.
- Trial name
- NCT05481619
- Testing
- Vedolizumab
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
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