Clinical trials: Modification
Pregnancy Trimester, First, Pregnancy Trimester, Second
Clinical Trial to Assess the Influence of Gestational Stage and Maternal Age on Arterial Stiffness of the Mother
This is a single-centre, open, parallel-group study with three age groups; no study medication or intervention will be provided. This is a longitudinal follow-up of physiological parameters.
- Conditions
- Pregnancy Trimester, First, Pregnancy Trimester, Second, Pregnancy Trimester, Third
- Trial name
- NCT00180219
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Breast Cancer
Weight Loss Plus Omega-3 Fatty Acids or Placebo in High Risk Women
The purpose of this study is to determine if high dose supplementation with the omega-3 fatty acids EPA and DHA, when added to a weight loss program, is well tolerated in the study population and if there is an increase in the…
- Trial name
- NCT02101970
- Testing
- Omega-3 Fatty Acids, Diet and Exercise
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Carol Fabian, MD
Constipation, Post-Op Complication
Does a Preoperative Bowel Regimen Change Time to First Bowel Movement After Robotic Sacral Colpopexy
The hypothesis is that starting a bowel regimen with Polyethylene Glycol prior to robotic assisted sacrocolpopexy will decrease time to first bowel movement after surgery.
- Trial name
- NCT04197869
- Testing
- Polyethylene Glycol Powder
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Trauma, Shock, Traumatic
Discriminant Ability of the Shock Index, Modified Shock Index, and Reverse Shock Index Multiplied by the Glasgow Coma Scale on Mortality in Adult Trauma Patients: A PATOS Study
We evaluated a cohort of adult trauma patients transported to emergency departments. The first vital signs were used to calculate the SI, MSI, and rSIG.
- Conditions
- Trauma, Shock, Traumatic, Morality
- Trial name
- NCT05549986
- Testing
- Observational
- Volunteers
- 105,641 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Military Operational Stress Reaction, Malnutrition (Calorie)
Physiological Response to Protein and Energy-enhanced Food Products During Winter Military Training
Soldiers commonly lose muscle mass during training and combat operations that produce large energy deficits (i.e., calories burned > calories consumed).
- Conditions
- Military Operational Stress Reaction, Malnutrition (Calorie), Weight Loss, Muscle Wasting
- Trial name
- NCT05210205
- Testing
- EAA, Energy Dense, Control
- Where
- Norway
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Cognitive Change
Digital Solution to Improve Cognitive Function in Epilepsy: PRODDIGE Project
Background: Epilepsy leads to cognitive impairment in 20-50%. Compared to seizures, these cognitive disorders are a major additional factor in occupational, social and family disability.
- Trial name
- PRODDIGE (NCT05057156)
- Testing
- cognitive rehabilitation
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Sleep, Diet Modification
Diet and Sleep Monitoring
This study will investigate the effect of two dietary patterns on sleep outcomes and measures of reported appetite. Participants will be given two different diets on two separate stays.
- Trial name
- NCT03257137
- Testing
- Diet Quality
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Postoperative Pain
Efficacy of Tramadol With Ropivacaine for Modified Pectoral Nerve Block in Breast Cancer Surgery
In this study the investigators will compare the post operative opoid consumption for patient undergoing modified radical mastectomy.
- Trial name
- NCT07775053
- Testing
- Pectoral Nerve Block
- Where
- Pakistan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Sargodha Medical College
Obesity, Childhood
Improving Childhood Obesity-Related Behavior Change Through Better Risk Communication
One-third of American children are overweight or obese, leading to an increased risk for cardiovascular disease (CVD), early mortality, and other risks throughout their lifespan relative to normal weight children.
- Trial name
- NCT03074929
- Testing
- Novel risk communication
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Change in Cognitive Function and Fatigue During Extended Performance of the Cognitive Demand Battery (CDB) at 1, 3 and 6 Hours Post Consumption, Change in Long Term Declarative Memory at 1, 3 and 6 Hours Post-intervention.
Plant Based Extracts and Cognition
Acute, randomized, placebo controlled, double blind, 4 arm crossover study to determine the effect of different combinations of plant based extracts on cognitive function and cerebral blood flow.
- Trial name
- CEOPTB (NCT02202629)
- Testing
- Beverage containing plant based extracts
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Gastroesophageal Reflux Disease, Minimal Change Disease
Diagnostic Value of Linked Color Imaging for Minimal Change Esophagitis in Nonerosive Reflux Esophagitis and GERD
Linked color imaging(LCI),a new system for endoscopy modality,creates clear and bright endoscopic images by using short-wavelength narrow-band laser light combined with white laser light on the basis of magnifying blue laser…
- Conditions
- Gastroesophageal Reflux Disease, Minimal Change Disease, Non-Reflux Esophagitis
- Trial name
- NCT03068572
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Elderly Person, Body Composition
Changes in Body Composition When Ingesting a Dairy Compound Enriched With Leucine
Controlled clinical trial, randomized by strata (sex and period of the study), with 6 parallel branches to the study depending on the type of product consumed and the type of physical exercise program performed, double-blind…
- Conditions
- Elderly Person, Body Composition, Physical Exercise
- Trial name
- LEUCI (NCT04345237)
- Testing
- dietary supplement consumption
- Where
- Spain
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Binge Eating Disorder, Overweight and Obesity
Neural Response to Food Stimuli: fMRI Changes Following Cognitive Behavioral Therapy for Binge Eating Disorder
The purpose of this research is to conduct a randomized controlled trial (RCT) assessing the impact of CBT on neural responses to binge eating stimuli.
- Trial name
- NCT03604172
- Testing
- Cognitive behavioral therapy, Waitlist
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Conditions in T74.31 or T76.31
The Nasal Changes Affected by Different Alar Base Suture Techniques After Maxillary LeFort I Osteotomy
study hypothesis 1. The aim of this study: How can the investigators predict and control the nasal changes after maxillary LeFort I osteotomy with 2 different alar base suture techniques ? 2.
- Trial name
- NCT01473745
- Testing
- conventional alar base cinch, modified alar base cinch
- Where
- Taiwan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Psychosis
Culturally Adapted Psychosocial Interventions for Early Psychosis in a Low-resource Setting
Primary Aims: To determine the clinical efficacy of Culturally adapted Cognitive Behavioral Therapy (CaCBT) and Culturally adapted Family Intervention (CulFI) compared to Treatment As Usual (TAU) on reducing overall symptoms of…
- Trial name
- CaPSI (NCT05814913)
- Testing
- CaCBT for psychosis, Culturally adapted Family Intervention (CulFI) for psychosis
- Where
- Pakistan
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Living and Learning
Healthy Volunteers
Gut Microbiome and Metabolic Health Study
The goal of this clinical trial is to assess whether TRPTI (oleoylethanolamide) can reduce plasma imidazole propionate levels and improve insulin sensitivity and metabolic health in healthy adults aged 18 years and above with BMI…
- Trial name
- IMPTRP (NCT07457723)
- Testing
- TRPTI 300mg
- Where
- Australia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Overweight and Obesity
High Intensity Interval Circuit Training on Resting Metabolic Rate in Overweight Adults
This is the first study to examine changes in resting metabolic rate up to 72 hours following an exercise session, and how these changes may be affected by 12 weeks of high intensity interval circuit training (HIICT).
- Trial name
- NCT03972059
- Testing
- Exercise training - Phase 1, Exercise training - Phase 2, Exercise training - Phase 3
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Diabetic Foot Ulcer
Plantar Pressure Distribution in Diabetic Foot Ulcer
The goal of this clinical trial is to find out the changes in peak pressure and pressure-time integral after twelve weeks from the initial utility of foot insoles and eight weeks later as a follow-up in diabetic foot ulcers.
- Trial name
- PPDDFU (NCT05888259)
- Testing
- foot insole
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pregnancy
Assessment of the Nutritional Status of Pregnant Women and Optimization of Prenatal Care Services
A national survey in Niger found that women and children are at risk of undernutrition and that many pregnant women don't visit health centers during pregnancy as often as is recommended.
- Trial name
- NCT01832688
- Testing
- Programmatic prenatal care optimization
- Where
- Niger
- Volunteers
- 2,306 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Focus of Study: 1- Effect of Tea Consumption on Gut Microbiota, Focus of Study: 2- Effect of Tea Consumption on Body-iron Status
Can the Reduction of Iron Availability Caused by Tea Consumption Change the Gut Microbiota Composition and Disrupt Host Body-iron Status
Iron is an essential micronutrient for nearly all living organisms, including microbes. The adult human body contains approximately 3-5 g of iron (45-55 mg/kg of body weight in adult women and men, respectively).
- Trial name
- NCT05019573
- Testing
- Black tea
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading
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