Clinical trials: Modification
Education, Asthma
Evaluating the Collaborative Management in Pediatrics (CMP) Training Program Among Pediatric Resident Doctors and Their Patients With Asthma or Obesity
Self-care behaviors are decisions and actions that people can take to improve their health or cope with a health problem. It is important for people with long-term illnesses to develop and maintain effective self-care behaviors.
- Conditions
- Education, Asthma, Obesity
- Trial name
- CMP (NCT00510341)
- Testing
- Collaborative Management in Pediatrics (CMP) Program
- Where
- 3 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Washington
Obesity, Inflammation
Gene Expression and Inflammation in Overweight Subjects
This study will look at gene expression (whether particular sets of genes are activated ["turned on"] or deactivated ["turned off"]) in overweight people as compared to non-overweight individuals.
- Conditions
- Obesity, Inflammation, Nutrition Therapy
- Trial name
- NCT00344266
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Physiological Response of Sphingolipids to a Single HIIT Session
Investigating the Circulating Sphingolipidome Response to a Single High-intensity Interval Training Session
The purpose of this study is to examine the response of a comprehensive panel of circulating sphingolipids to a single high-intensity interval training (HIIT) session in healthy individuals in their twenties.
- Trial name
- SphingoHIIT (NCT05390866)
- Testing
- HIIT
- Where
- Switzerland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Basel
Breast Cancer
Peer Counseling for Weight Loss
The efficacy of peer counseling for weight loss maintenance is being tested in obese and overweight African American breast cancer survivors.
- Trial name
- NCT00120029
- Testing
- weight loss counseling
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Rumination
Mechanisms and Predictors of Change in App-Based Mindfulness Training for Adolescents
A growing body of research implicates rumination as being a transdiagnostic risk factor involved in the development of depression and anxiety in youth.
- Trial name
- NCT04697966
- Testing
- Mindfulness (Headspace) App, Active Control Condition ("Recharge" condition delivered in Headspace app)
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Blood Loss, Surgical, Postoperative Hemorrhage
Study of the Hemorai Vysio Wearable Device for Monitoring Changes Related to Blood Loss in Patients During and After Surgery.
The goal of this clinical trial is to learn whether the Hemorai Vysio wearable device can be used safely and feasibly to track relative changes over time in tissue oxygen, hemoglobin-related signals, blood flow, and oxygen use…
- Trial name
- VYSIO-FEASIBIL (NCT07826637)
- Testing
- Wearable optical hemodynamic monitoring device
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hemorai Inc
Bimaxillary Proclination
Anchorage Reinforcement in Bimaxillary Proclination Cases
Bimaxillary protrusion are common in Malaysia due to the prevalence in the two biggest races (Malay and Chinese). However, evidence for treatment methods and outcomes for bimaxillary protrusion patients are scarce.
- Trial name
- NCT04705545
- Testing
- transpalatal arch group, Nance button
- Where
- Malaysia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Menopause, Cognitive Change
PhytoSERM to Prevent Menopause Associated Decline in Brain Metabolism and Cognition
This is a proof-of-concept phase 2 clinical trial to investigate the safety and effect of the phytoestrogenic supplement PhytoSERM on regional brain metabolism by fluorine-18 fluorodeoxyglucose positron emission tomography…
- Conditions
- Menopause, Cognitive Change, Brain Disorder, Metabolic
- Trial name
- NCT05664477
- Testing
- PhytoSERM
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Roberta Brinton
Neurocognitive Model, Decision-Making
Motivation, Learning and Decision Making in Changing Environments
The main objective of this study is to develop a models of sequential decision-making, learning and motivation that includes emotions as driving forces of adaptive behaviour.
- Trial name
- MOTILEARN (NCT07314112)
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Deep Carious Lesions
SDF Modified Hall Technique Vs. Conventional Pulpotomy for Management of Carious Primary Molars
Dental caries in primary teeth is considered the most common oral disease of childhood and it has been investigated in many places throughout the world.
- Trial name
- NCT05240365
- Testing
- SDF modified Hall technique, Conventional pulpotomy and stainless steel crown
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sondos Naserallah
HIV Prevention, Sexually Transmitted Diseases
STI Care Model to Reduce Genital Inflammation and HIV Risk in South African Women
The goal of this prospective cohort study is to determine if a model of care including point-of-care testing, immediate therapy, expedited partner therapy and test of cure will result in a higher cure rate and a lower recurrence…
- Trial name
- NCT03407586
- Testing
- Point-of-care STI testing
- Where
- South Africa
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Centre for the AIDS Programme of Research in South Africa
Obesity, Cardiovascular Risk Factor
Healthy Nordic Foods to Prevent Cardiometabolic Risk in Obese Subjects
This project will examine whether long-term consumption of healthy Nordic foods can maintain a healthy weight also after weight loss, and decrease abdominal fat accumulation and cardiometabolic risk.
- Conditions
- Obesity, Cardiovascular Risk Factor, Diet Modification
- Trial name
- NCT03102853
- Testing
- Nordic diet, Control diet
- Where
- Sweden
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lund University
Healthy Participants
The Change in Cutaneous Temperature When Using Acupuncture at TB-3 and BL-65 Acupoints in Healthy Participants
For more than 2,500 years, traditional medicine, especially acupuncture, has been widely used in health care and recognized by the World Health Organization (WHO) to manage various diseases.
- Trial name
- NCT06200337
- Testing
- Fine needle acupuncture
- Where
- Vietnam
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loc Cong Dai Tran, MD
Dermal Filler, Hyaluronic Acid
Evaluate the Safety and Effectiveness of Sodium Hyaluronate When Used for the Correction of Nasolabial Folds
The aim of this study is to evaluate the safety and effectiveness of pain relief of modified sodium hyaluronate gel for injection when used for the correction of moderate or severe nasolabial folds.
- Conditions
- Dermal Filler, Hyaluronic Acid, Lidocaine, Nasolabial Fold
- Trial name
- NCT04569045
- Testing
- HA+Lidocaine, HA
- Where
- 2 sites in China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- SciVision Biotech Inc.
Obesity, Overweight
Calcium Supplementation for a Healthy Weight-Lite (CaSHeW Lite)
The purpose of the study is to find out if taking calcium and vitamin D supplements, while following a low-calorie diet, can help people lose weight.
- Trial name
- NCT00386672
- Testing
- Reduced energy (lite) OJ fortified with Calcium and Vitamin D, Nutrition Counseling, Reduced energy (lite) OJ without Calcium and Vitamin D
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pilonidal Sinus, Pilonidal Disease of Natal Cleft
Asymmetric Primary Closure and Additional Skin Excision Technique.
The aim of this study was to reduce the residual dead-space volume with a modification following the standard Karydakis procedure.
- Conditions
- Pilonidal Sinus, Pilonidal Disease of Natal Cleft, Surgical Technique
- Trial name
- NCT03424057
- Testing
- Asymmetric Primary Closure and Additional Skin Excision Technique, Standard Karydakis technique.
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Siverek Devlet Hastanesi
Healthy
Measurement of Retinal Venous Pressure Under Short-term Low-oxygen Environment
The hypothesis is that the pressure in the retinal veins increases under a short-term lack of oxygen and leads to a decreased blood circulation.
- Trial name
- NCT01771757
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
User Experience
Evaluation of the User Experience of an Innovative Hospital Room Prototype Adapted to the Elderly
Nowadays in France, the standards of hospital rooms are being questioned in view of the particularities of certain populations admitted to hospitals.
- Trial name
- HospiSenior-UX (NCT05126212)
- Testing
- User experience
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Obesity
Our Year of Healthy Living (Formative Research & Intervention)
The purpose of this study is to evaluate the effect of a 7-month social marketing program - Healthy Me, Healthy We (previously called Our Year of Healthy Living) - in improving preschool children's (3-4 years) diet and physical…
- Trial name
- NCT02330354
- Testing
- Healthy Me, Healthy We
- Where
- United States
- Volunteers
- 2,293 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Central Diabetes Insipidus
Plasma Oxytocin Changes in Response to Low-dose MDMA vs. Placebo in Patients With Arginine Vasopressin Deficiency and Healthy Controls
The investigator hypothesize that low-dose MDMA (3,4-methylenedioxymethamphetamine) will produce a sufficiently strong oxytocin stimulation in healthy controls and no relevant increase in patients.
- Trial name
- OxyMAX (NCT06789705)
- Testing
- MDMA
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
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