Clinical trials: Modification
Growth Hormone Deficiency
Adipose Tissue and Circulating Markers of Inflammation in GH Deficiency and Changes With GH Therapy
In order to examine the effect of GH on adipose tissue inflammation, this study will examine adipose tissue and serum inflammation in patients with GH deficiency before and after GH therapy.
- Trial name
- NCT03225755
- Testing
- Growth hormone
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Columbia University
Obesity, Weight Gain
Role of Dairy Products in Weight Maintenance
The goal of the current study is to determine the role of dairy in similarly preventing weight and fat re-gain in obese adults who have successfully completed a weight loss diet program.240 obese subjects will undergo a…
- Trial name
- NCT00686426
- Testing
- Dairy Foods
- Where
- 2 sites in United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Optic Nerve Sheath Diameter
Changes of Optic Nerve Sheath Diameter Between Obese and Non-obese Patients Undergoing Laparoscopic Gynecological Surgery
This study aims to compare the change of optic nerve sheath diameter in obese and non-obese patients undergoing laparoscopic gynecological surgery in a steep Trendelenburg position.
- Trial name
- NCT04427085
- Testing
- Ultrasound assessment of optic nerve sheath diameter
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- SMG-SNU Boramae Medical Center
Hearing Loss
Assessment of Novel Sound Changing Principles in Hearing Instruments to Determine Their Application - 2019_33
Participants will complete a listening task in a simulated reverberant environment. Participants are seated and instructed to look at a fixation cross while a sentence is played.
- Trial name
- NCT04167735
- Testing
- Hearing Aid without Reverberation Canceller (RevC)., Hearing Aid Reverberation Canceller enabled (RevC_1)
- Where
- Switzerland
- Volunteers
- 18 people
- Sponsor
- Sonova AG
Celiac Disease
Saliva Composition and Oral Hygiene in Children With Celiac Disease Before and After the Change in Diet
The celiac disease (CD) is a disease with an immune and genetic component that is activated by the presence of gluten, and damages the intestine mucosa and causes malabsorption of food.
- Trial name
- NCT01129908
- Volunteers
- 90 people
- Sponsor
- Hadassah Medical Organization
Electromyography
Age-related Changes of Shoulder Muscles
A cross-sectional descriptive study, in which the surface electromyographic activity of five shoulder muscles was compared in three populations: older adults, middle-aged adults and young adults.
- Trial name
- SEMG (NCT02974452)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Healthy Adults
A Study to Learn About How the Study Medicines Called Itraconazole and Probenecid Change How the Body Processes PF-07220060
The purpose of the study is to see and learn the effect of multiple doses of a strong CYP3A4 inhibitor and a potent UGT2B7 inhibitor on the PK of PF-07220060.
- Trial name
- NCT07160738
- Testing
- PF-07220060, Itraconazole, Probenecid
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pfizer
Anxiety Disorders, Depressive Disorder
Islamic-Oriented vs. Standard Ericksonian Hypnotherapy for Anxiety and Depression
This randomized controlled trial (RCT) aims to compare the effectiveness of Islamic-Oriented Ericksonian Hypnotherapy (IEH) and Standard Ericksonian Hypnotherapy (SEH) in reducing symptoms of anxiety and depression.
- Trial name
- IEH-RTC (NCT06844058)
- Testing
- Islamic-Oriented Ericksonian Hypnotherapy (IEH), Standard Ericksonian Hypnotherapy (SEH)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Nisantasi University
Metastatic Prostate Cancer
Psma Intensity Can be Altered by Androgen and Phospho-SrC Obstruction
The study's purpose is to understand the appearance of your prostate-specific membrane antigen (PSMA) PET scan after you take 14 days of treatment with a drug called dasatinib alone or in combination with anti-testosterone drug…
- Trial name
- PICASSO (NCT04925648)
- Testing
- Dasatinib, Darolutamide
- Where
- 2 sites in Australia
- Volunteers
- 4 people
- Sponsor
- St Vincent's Hospital, Sydney
Acute Myeloid Leukemia, Cachexia
Investigation of the Gut Microbiota in Patients With Acute Myeloid Leukemia
This cohort study aims to investigate the composition and activity of the gut microbiota of patients newly diagnosed for acute myeloid leukemia (AML), in relationship with their food habits and cachectic hallmarks.
- Trial name
- MicroAML (NCT03881826)
- Testing
- collection of clinical data and biological samples
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Obesity
ENDObesity® II Study: TransPyloric Shuttle® System for Weight Loss
The purpose of this clinical research trial is to study safety and effectiveness of the TransPyloric Shuttle System (TPSS) for weight reduction in patients who are considered medically obese.
- Trial name
- NCT02518685
- Testing
- TransPyloric Shuttle, Lifestyle Counseling
- Where
- 9 sites in United States
- Volunteers
- 302 people
- Sponsor
- BaroNova, Inc.
Ankylosing Spondylitis
Study to Assess Change in Disease Activity and Adverse Events of RINVOQ in Adult Participants With Ankylosing Spondylitis in the Real-World Japan
Axial spondyloarthritis (axSpA), which encompasses radiographic axSpA (r-axSpA, also known as ankylosing spondylitis [AS]) is an immune-mediated inflammatory disease primarily affecting the axial skeleton.
- Trial name
- SELECT AXIS RW (NCT05609643)
- Where
- 61 sites in Japan
- Volunteers
- 69 people
- Sponsor
- AbbVie
PMS, Menstrual Cramp
A Randomized Placebo-Controlled Study to Evaluate the Effects of a Gummy and Capsule Supplement on Symptoms of Premenstrual Syndrome
This virtual, randomized, placebo-controlled clinical trial evaluates the effectiveness of a PMS capsule and PMS gummy in alleviating premenstrual syndrome symptoms over 12 weeks.
- Conditions
- PMS, Menstrual Cramp, Mood Change
- Trial name
- NCT06763809
- Testing
- PMS Capsule, PMS Gummy
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Semaine Health
Consciousness Disorders
Etiologies, Definitive Diagnosis and Patient Outcomes in Altered Level of Consciousness in the Emergency Department
When someone starts acting differently in terms of how alert or awake they are, it can be a tough situation for emergency (ER) department doctors.e exact and definitive etiologies of ALOC that can be intracranial or extracranial.
- Trial name
- NCT06744114
- Testing
- Consciousness in the Emergency Department
- Where
- Pakistan
- Volunteers
- 1 people
- Sponsor
- Superior University
Post Operative Pain
A Comparison Between The Efficacy of Modified Thoracoabdominal Plane Block Via Perichondral Approach (M-TAPA) And External Oblique Intercostal Plane Block (EOIPB) in Patients Undergoing Laparoscopic Cholecystectomy Surgeries (LC)
Because laparoscopic procedures have a number of benefits over open procedures, they have completely changed the surgical industry.(1) Laparoscopic cholecystectomy (LC) is a minimally invasive technique that usually yields less…
- Trial name
- NCT06810206
- Testing
- Bilateral Ultrasound Guidance M-TAPA, Bilateral Ultrasound Guidance EOIPB
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Thumb Injury, Tendon Injuries
Functional Improvement and Fine Dexterity in Thumb Tendon Injuries
Considering the thumb's contribution to fine dexterity and precision grip, this study aims to evaluate fine manual dexterity alongside functional outcomes following isolated thumb tendon injuries, and to examine the relationship…
- Trial name
- NCT07388316
- Testing
- Questionnaire and Physical Exam
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Pamukkale University
Depression
ECT/Succinylcholine: Biochemical, Serum and Cardiovascular Changes
This study will be conducted to determine the pharmacodynamics, cardiovascular and biochemical effects of succinylcholine when given during electroconvulsive therapy. (ECT).
- Trial name
- NCT00750906
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of California, San Francisco
Ovarian Cancer, Endometrial Cancer
Targeted Disruption to Cancer Metabolism and Growth Through Dietary Macronutrient Modification
The objective of this investigation is to examine the effects of 12 weeks of usual care plus a ketogenic diet (KD) or usual care plus dietary recommendations endorsed by the Academy of Nutrition and Dietetics (AND) in women with…
- Trial name
- NCT03171506
- Testing
- Ketogenic diet, AND diet
- Volunteers
- 57 people
- Sponsor
- University of Alabama at Birmingham
Infertility
The Pharmacokinetic and Bioavailability of GenSci094 Before and After a Change in Manufacturing Site
The bioavailability study is intended to evaluate the pharmacokinetic (PK) characteristics and the bioavailability of the two formulations in humans before and after the change of production site, in order to assess the possible…
- Trial name
- NCT06095206
- Testing
- GenSci094
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Spinal Cord Injury
"Guarantee Assessment in Skin Prevention Adapted to Real Life With a Connected Device After a Spinal Cord Injury."
The investigators propose to test an embedded device on the seat of the wheelchair of paraplegic or tetraplegic patients (Gaspard), allowing on the one hand the continuous measurement of the pressures of seat, on the other hand a…
- Trial name
- GASPARD-SCI (NCT05403606)
- Testing
- GASPARD®
- Where
- France
- Volunteers
- 134 people
- Sponsor
- Nantes University Hospital
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