Clinical trials: Molar Extraction Socket
Tooth Extraction, Socket Preservation
Injectable Platelet-rich Fibrin and Advanced Platelet-rich Fibrin With Xenograft on the Socket Preservation of Mandibular Extracted Molars
Different materials and techniques are employed for socket preservation to reduce the alveolar bone resorption in both the horizontal and vertical dimensions as well as the soft tissue collapse after tooth extraction.
- Trial name
- NCT06936358
- Testing
- Control, A-PRF, I-PRF
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Hams Hamed Abdelrahman
Dry Socket, Postoperative Infections
The Effect of Chlorhexidine + Hyaluronic Acid on Postoperative Wound Healing After Lower Third Molar Removal
Our aim is to evaluate chlorhexidine-hyaluronic acid containing gel on postoperative wound healing regarding impacted lower third molar surgery.
- Trial name
- NCT07044219
- Testing
- Third molar surgery
- Where
- Hungary
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy
Evaluation of the Use of CGF Based Sticky Bone Packed in Fresh Odontectomy Site of Impacted Lower 3rd Molars
This clinical study aims to evaluate the effectiveness of Concentrated Growth Factor (CGF)-based sticky bone in enhancing bone healing after surgical removal of impacted mandibular third molars.
- Conditions
- Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy, Postoperative Pain Management in Oral Surgery, Concentrated Growth Factor for Extraction Socket Healing
- Trial name
- CGF (NCT07517835)
- Testing
- Concentrated growth factors
- Volunteers
- 10 people
- Sponsor
- Cairo University
Tooth Extraction, Tooth Extraction Site Healing
Comparison of Intraligamentary Anesthesia With the Inferior Alveolar Nerve Block for the Extraction of Mandibular Molars.
Local anaesthesia or numbing is done before tooth extraction. This study compares two different methods of numbing molar teeth before extraction.
- Trial name
- NCT06611865
- Testing
- Intraligamentary anaesthesia, Inferior alveolar nerve block
- Where
- Pakistan
- Volunteers
- 535 people
- Sponsor
- Hamza Zia Ahmed
Mesh, Healthy Volunteer
Improving Healing in Children After Tooth Extraction Using Laser Therapy or Hyaluronic Acid
Tooth extraction may be an unpleasant and painful experience for children, Post-extraction wound healing. Low-level laser therapy (LLLT) is a widely used adjuvant treatment for wound healing, resulting in both an increase in cell…
- Conditions
- Mesh, Healthy Volunteer, Low Level Laser Therapy, Hyaluronic Acid Gel for Preservation the Extraction Socket
- Trial name
- LLLT vs HA (NCT07205640)
- Testing
- Low-Level Laser Therapy, Hyaluronic Acid (HA)
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Immediate Implant Placement in Mandibular Molar Extraction Sockets
3D-Printed PLA Guide Versus Resin Guide in Mandibular Molar Implant Placement
This randomized clinical trial compares two tooth-supported computer-guided surgical guide systems for immediate implant placement in mandibular molar extraction sockets: a patient-specific 3D-printed PLA guide system and a…
- Trial name
- CGIIPMM-PLA-MR (NCT07826039)
- Testing
- immediate implant placement using PLA guide, Immediate implant placement using Modified resin guide.
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mohamed Esmail Ahmed Hassan
Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy
Evaluating The Use of CGF Made Gel in Mandibular Extraction Sites of Lower Impacted 3rd Molars.
The goal of this clinical trial is to learn if Concentrated Growth Factor (CGF) Gel help improve bone healing and reduce pain after the surgical removal of impacted lower third molars.
- Conditions
- Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy, Postoperative Pain Management in Oral Surgery, Concentrated Growth Factor for Extraction Socket Healing
- Trial name
- CGF (NCT07520097)
- Testing
- Concentrated Growth Factor (CGF) Gel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Osteitis
The Effect of Post-extraction Collagen Sponge Application on Alveolar Osteitis
The goal of this randomized controlled trial is to compare pain, mouth opening, and alveolar osteitis following surgical extraction of bilateral symmetrical impacted lower third molars using two types of wound closures.
- Trial name
- NCT05850650
- Testing
- Application of a collagen sponge after surgical extraction of impacted 3rd molar, No collagen sponge application after surgical extraction of impacted 3rd molar
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Post-surgical Oral Wounds, Oral Cavity Surgery
Evaluation of the Performance and Safety of a Linear Hyaluronic Acid-Based Medical Device in the Treatment of Surgical Wounds in the Oral Cavity.
The PR-DENT study is an interventional, single-center, controlled clinical investigation aimed at evaluating the clinical performance and safety of a Class III medical device based on linear hyaluronic acid for the treatment of…
- Conditions
- Post-surgical Oral Wounds, Oral Cavity Surgery, Wound Healing/Regeneration, Dental Extraction Sites
- Trial name
- PR-DENT (NCT07421934)
- Testing
- Intervention: Linear Hyaluronic Acid (Gumblast), Control: Standard Surgical Procedure
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- The Wave Innovation Group s.r.l.
Socket Preservation
Socket Preservation After Surgical Extraction of Impacted Lower Third Molar
The aim of this study will be to evaluate socket preservation using autogenous particulate dentin in combination with liquid platelet-rich fibrin versus bone allografts and collagen cone after surgical extraction of the…
- Trial name
- NCT06716736
- Testing
- socket preservation using dentine graft mixed with i-PRF, socket preservation using bone allograft, socket preservation using collagen cone
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Wael Mohamed
Pain, Oral Surgery
Hyaluronic Acid and Amino Acid Gel Applied to the Alveolar Socket After Mandibular Third Molar Extraction
Objective: The study aimed to assess the effect of topical application of an amino acid + sodium hyaluronate acid gel after lower third molar extraction.
- Conditions
- Pain, Oral Surgery, Third Molar Extraction
- Trial name
- NCT03428698
- Testing
- Aminogam
- Where
- Italy
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Padova, School of Dental Medicine
Stem Cell, Third Molar
Effect of Dental Pulp Stem Cells and L-PRF After Impacted Third Molar Extraction
The purpose of this study is to compare the clinical and radiographic effectiveness of Leukocyte-Platelet Rich Fibrin (L-PRF) and L-PRF combined with dental pulp stem cell (DPSC) application to the extraction socket of mandibular…
- Conditions
- Stem Cell, Third Molar, Periodontal Pocket
- Trial name
- NCT04641533
- Testing
- L-PRF + DPSC, L-PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Baskent University
Molar Extraction Socket
Clinical Evaluation of the Effectiveness of Biomimetic Hemostatic Sponges ColiSorB Following Dental Extraction
This study tested three different treatment groups in a fair and organized way. It included people who came to Cairo University's Dental Department to have a back tooth (molar) removed and who qualified to join.
- Trial name
- NCT07179523
- Testing
- Hemostatic gelatin sponge, Hemostatic Agent
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sara Omar
Impacted Third Molar Tooth
Gum Health Gel in Post Extraction Sockets
This research studies the effectiveness of the Gum Health gel in minimizing post operative sequelae associated with the surgical removal of impacted mandibular third molars
- Trial name
- Gum Health gel (NCT06251141)
- Testing
- Gum Health gel, Gel foam
- Where
- Iraq
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Socket Preservation, Alveolar Ridge Preservation
Demineralized Dentin Matrix Versus Mineralized Plasmatic Matrix on Alveolar Ridge Preservation in Molar Extraction Sites
When a tooth is removed, the bone around it (called the alveolar ridge) naturally shrinks. This study compares two bone grafting materials to find out which one better preserves bone after molar extraction: Demineralized Dentin…
- Trial name
- NCT07239193
- Testing
- Demineralized Dentin Matrix (DDM) + Platelet-Rich Fibrin (PRF), Mineralized Plasmatic Matrix (MPM)
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Impacted Mandibular Third Molar, Alveolar Bone Loss
Healing of Mandibular Third Molar Extraction Sockets Using Platelet Concentrates and Photobiomodulation
Surgical removal of impacted mandibular third molars is a common procedure that may be associated with postoperative pain, swelling, limited mouth opening, and delayed bone healing.
- Conditions
- Impacted Mandibular Third Molar, Alveolar Bone Loss, Impacted Mandibular Third Molar Extraction
- Trial name
- NCT07324213
- Testing
- Mandibular Third Molar Extraction With Primary Wound Closure, Autologous Platelet Concentrates, Photobiomodulation
- Where
- Poland
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Medical Innovation Center Wroclaw
Tooth Loss and Rehabillitation, Immediate Implant Placement in Mandibular Molar Extraction Sockets
Comparison Between Xenograft and Extended PRF as Jumping Gap Grafting Material Versus Natural Healing of the Socket Without Any Material.
This study aims to clinically and digitally evaluate immediate implants placed in mandibular molar extraction sockets and compare the outcomes of xenograft, e-PRF, and no grafting material within the jumping gap.
- Conditions
- Tooth Loss and Rehabillitation, Immediate Implant Placement in Mandibular Molar Extraction Sockets, Jumping Gap
- Trial name
- NCT07797452
- Testing
- Xenograft jumping gap filling material, e-PRF jumping gap filling material
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Implant Osseointegration, Implant Osteotomy
"Osseodensification Efficacy on Molar Septum Expansion in Immediate Molar Implant Placement
The ideal positioning of immediate implants in molar extraction sockets often requires the osteotomy to be in the interradicular septum, which can be challenging in some cases, with traditional site preparation techniques.
- Conditions
- Implant Osseointegration, Implant Osteotomy, Implant Placement, Implant Primary Stability
- Trial name
- NCT07108361
- Testing
- Osseodensification, conventional drilling
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Alveolar Osteitis
Comparative Efficacy of Amoxicillin, Metronidazole, and Chlorhexidine in Preventing Alveolar Osteitis
This study will compare the effectiveness of amoxicillin, metronidazole, and chlorhexidine in preventing alveolar osteitis (dry socket) following lower third molar extraction.
- Trial name
- NCT07833176
- Testing
- Amoxicillin, Metronidazole, Chlorhexidine
- Where
- Pakistan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Extraction Socket Healing
Assessment of Topical Application of Chitosan 0.2% Chlorhexidine Gel on Wound Healing in Diabetic Patients
Despite efforts to prevent postoperative discomfort, immediate side effects of surgical extraction of lower molars include bleeding at the site of extraction, inflammation, pain, and alveolar osteitis especially in diabetic…
- Trial name
- NCT07429812
- Testing
- Surgical extraction of the offending tooth will be performed under local anesthesia using inferior alveolar nerve block technique with buccal mucosa infiltration, make an incision on the gingival tis
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tanta University