Clinical trials: Monitoring During Anesthesia
Cardiac Output
Comparability of Transesophageal Echocardiography and FloTrac/Vigileo System Three Different Positions
The use of cardiac output monitoring to guide intraoperative fluid management and inotropic drugs as part of a hemodynamic therapy algorithm reduce the complication rate in major abdominal surgery.
- Trial name
- NCT05508711
- Testing
- FloTrac/Vigileo system (© Edwards Lifesciences) (Edwards Lifesciences, Irvine, CA) device
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Université Libre de Bruxelles
Anesthesia, Nociceptive Pain
NIPE Monitoring Values During Routine Pediatric Anesthesia
Description of the standard values and fluctuations of the new NIPE index during routine pediatric anesthesia. NIPE monitor connected to anesthesia monitor, displays an instantaneous value ranging from 0 to 100.
- Trial name
- OMNIPED (NCT04432480)
- Testing
- NIPE (Newborn Infant Parasympathetic Evaluation) monitoring
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Lille
Brain Injury
Macro- and Microcirculation Crosstalk in Brain-damaged Patients Under Anesthesia or in Intensive Care
In patients with severe brain injury, maintenance and control of blood pressure is at the very first point in the management strategy, whether in anesthesia or in intensive care.
- Trial name
- MICRONOR (NCT05285514)
- Testing
- Comparison of macro- and microcirculatory parameters
- Where
- France
- Volunteers
- 85 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infertility, Female, Anesthesia Awareness
Preoperative Anxiety at Oocyte Retrieval
This study evaluated the effects of preoperative anxiety and dosage of anesthesia on IVF success. Half of participants according to the recorded Beck's Anxiety Inventory (BAI) score: a low-anxiety group, while the other half…
- Conditions
- Infertility, Female, Anesthesia Awareness, Anxiety State
- Trial name
- NCT03134651
- Testing
- Monitoring brain function, propofol
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Trakya University
Nociceptive Pain, Surgical Procedure, Unspecified
Automatic Remifentanil Administration Guided by ANI During Propofol Anesthesia
Prospective Randomized Monocentric Clinical Trial during propofol anesthesia. The aim of the study is to test whether the use of a medical device designed to automatically administer remifentanil during surgery based on expert…
- Trial name
- ANI-LOOP (NCT03556696)
- Testing
- ANI-REMI-loop, remifentanil pK/pD target administration device, Remifentanil
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Lille
Tethered Spinal Cord, Brain Tumor
Dexmedetomidine on Intraoperative Somatosensory and Motor Evoked Potential Monitoring During Neurosurgery in Pediatric Patients
The investigators want to know if using the study drug dexmedetomidine will improve nerve wave readings during neurosurgery. These readings are done many times during surgery while the patient is asleep.
- Conditions
- Tethered Spinal Cord, Brain Tumor, Cranio Cervical Compression
- Trial name
- NCT01512147
- Testing
- Isoflurane, Propofol, Dexmedetomidine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Oregon Health and Science University
Anesthesia Induced Hypotension, Hypotension Drug-Induced
Comparison of Pleth Variability Index vs. Diastolic Shock Index for Predicting Hypotension During Anesthesia Induction
This study aims to explore the frequent occurrence of hypotension during anesthesia induction due to anesthetic drugs or fasting. Predicting this condition is important for patient safety and anesthesia management.
- Trial name
- NCT06589674
- Testing
- Pulse variability index measurement, Diastolic shock index
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Kocaeli City Hospital
Cesarean Section
Development of a Risk Prediction Model for Post-Spinal Anesthesia Hypotension During Cesarean Delivery Using Heart Rate, Blood Pressure, Perfusion Index, ECG Waveforms, and SpO₂ Waveforms
Spinal anesthesia is the preferred anesthetic technique for patients undergoing cesarean section. Compared with general anesthesia, spinal anesthesia offers multiple advantages.
- Trial name
- NCT07689825
- Testing
- Standard clinical spinal anesthesia and routine intraoperative monitoring
- Where
- China
- Volunteers
- 145 people
- Sponsor
- Peking University Shenzhen Hospital
Liver Transplant Surgery
Sugammadex and Quantitative Monitoring in "Fast-Track Anesthesia" During Liver Transplantation
The purpose of this research is to estimate the frequency of postoperative lasting muscle weakness in patients receiving Sugammadex after undergoing liver transplant surgery by using electromyographic device (EMG), such as…
- Trial name
- NCT05216991
- Testing
- TetraGraph on dominant hand, TetraGraph on non-dominant hand
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Mayo Clinic
Hemodynamics
Non-invasive vs Invasive Cardiac Output Monitoring During Cesarean Section
This study aims to evaluate the consistency of hemodynamic monitoring between NICAP and NICCO technologies (T20A; Chongqing, China) and the traditional pulse wave analysis method (EV1000; USA).
- Trial name
- NCT06473818
- Testing
- Non-invasive monitoring, Invasive monitoring
- Where
- China
- Volunteers
- 45 people
- Sponsor
- General Hospital of Ningxia Medical University
Maternal Haemodynamic Stability
Maternal Haemodynamic Changes After Crystalloid Co-loading and Phenylephrine Versus Phenylephrine Alone During Spinal Anaesthesia for Elective Caesarean Delivery
Spinal anaesthesia is the anaesthetic technique of choice for elective caesarean delivery. Hypotension, a result of the decrease in systemic vascular resistance caused by spinal anaesthesia, is a frequent complication occurring…
- Trial name
- NICOM-USB (NCT04026685)
- Testing
- Phenylephrine infusion, Phenylephrine infusion and Ringer-Acetate bolus
- Where
- Switzerland
- Volunteers
- 66 people
- Sponsor
- University Hospital, Basel, Switzerland
Anesthesia Complication, Surgical Blood Loss
Cerebral Oxygenation, Different Measurement Points and Their Correlation in Pediatric Population
Children who undergo surgery routinely for surgery that risk high levels of circulatory changes (eg heart surgery) is currently used routinely monitoring as regional oxygenation technology of the brain (NIRS).
- Trial name
- NCT03136952
- Testing
- NIRS frontal and occipital
- Where
- Sweden
- Volunteers
- 17 people
- Sponsor
- Göteborg University
General Anesthesia, Ventilator-Induced Lung Injuries
Prevention of Postoperative Respiratory Complications
Given the huge number of patients mechanically ventilated during general anaesthesia, optimizing alveolar recruitment by limiting pulmonary and systemic aggression is a key objective for further progress in perioperative patient…
- Conditions
- General Anesthesia, Ventilator-Induced Lung Injuries, Postoperative Respiratory Complications
- Trial name
- RAMAGE (NCT06899295)
- Testing
- Continuous measurement of esophageal pressure Peso (cmH2O), Measurement of impedance variation with each respiratory cycle (EIT), Z in ohm, Measurement of regional respiratory compliance (EIT), Ohm/cmH2O
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anesthesia Brain Monitoring, Ketamine
Effect of Ketamine on BIS Values
Aim of this trial is to define if Concentration at the effector site (Ce) of Ketamine, calculated with DOMINO model infusion pump are correlated with Bispectral Index BIS values during general anaesthesia for breast surgery.
- Trial name
- NCT05288764
- Testing
- Bispectral Index
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- University of Padova
Anesthesia, Spinal, Hip Fractures
Haemodynamic Effects and Complications of Continuous Versus Single-shot Spinal Anaesthesia for HIP Fracture Surgery
This research project aims to identify a safer method of spinal anaesthesia for elderly patients undergoing surgical stabilisation of proximal femoral fractures.
- Trial name
- CHIPS (NCT07358299)
- Testing
- Bupivacaine Spinal 0,5% Heavy - bolus, Bupivacaine Spinal 0,5% Heavy - titration
- Where
- 2 sites in Poland
- Volunteers
- 216 people
- Sponsor
- Centre of Postgraduate Medical Education
Bladder Tumors, Spinal Anesthesia
Magnesium vs. Dexmedetomidine in TURBT Under Spinal Anesthesia
This randomized controlled trial evaluated the effects of intraoperative intravenous magnesium sulfate versus dexmedetomidine on postoperative pain, analgesic consumption, hemodynamic stability, and respiratory function in…
- Conditions
- Bladder Tumors, Spinal Anesthesia, Postoperative Pain, Magnesium Sulfate
- Trial name
- TURBT (NCT07445451)
- Testing
- magnesium sulfate, Dexmedetomidine, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Regional Anesthesia, Pain
Nociception Index Level (NOL) Perioperative Monitoring During Regional Anesthesia
This prospective observational study was conducted to assess pain using NOL index under locoregional anesthesia for orthopedic surgery of the upper limb.
- Conditions
- Regional Anesthesia, Pain, Intraoperative Monitoring
- Trial name
- NOL and LRA (NCT06300606)
- Testing
- NOL monitoring
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- American Hospital of Paris
General Anesthesia
Comparison of Two Electroencephalograms (EEG) Monitors in Patients Undergoing General Intravenous Anesthesia
Quantium Medical Company has an ElectroEncephalograph-based (EEG-based) algorithm with two outputs: qCON for unconsciousness and qNOX for anti-nociception.
- Trial name
- Bis-qCON-IV (NCT03753217)
- Testing
- qCON Monitor
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Hopital Foch
Hypovolemia, Somatic Pain
Influence of Variations of Systemic Venous Return on Analgesia Nociception Index (ANI) During General Anaesthesia
The purpose of this study is to determine whether the value of analgesia nociception index (ANI) is influenced by variations of systemic venous return (cardiac preload) under general anaesthesia.
- Trial name
- NCT02193412
- Testing
- noxious stimulus, change in operating table slope: head-down tilt position, change in operating table slope: head-up tilt position
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Lille
Pain
Pupillary Dilation Reflex (PDR) Evaluation During General Anesthesia
In this study, the pupillary dilation reflex is measured as a nociceptive indicator during elective abdominal surgery under general anesthesia.
- Trial name
- NCT02942316
- Testing
- Pupil dilation reflex measurement
- Where
- Belgium
- Volunteers
- 41 people
- Sponsor
- University Hospital, Antwerp