Clinical trials: Monosymptomatic Nocturnal Enuresis
Nocturnal Enuresis
A New Check-list Method for Nocturnal Enuresis
The study is aimed to demonstrate the benefits of newly formed written check-list of behavioral instructions and investigate its effects on parent's awareness, consciousness and motivation toward MNE.
- Trial name
- NCT03510975
- Testing
- desmopressin melt form 120 μg, Verbal behavioral therapy, Behavioral therapy with written check-list
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital
Nocturnal Enuresis
Urotherapy vs. Urotherapy With Constipation Treatment for Nocturnal Enuresis
Constipation treatment has been found to ameliorate symptoms in some patients with nocturnal enuresis (bed wetting at night). This study aims to explore if treatment of patients without overt constipation (As defined by the ROME…
- Trial name
- NCT02337413
- Testing
- Polyethylene glycol 3350, Constipation behavioral therapy, Urotherapy
- Where
- Israel
- Sponsor
- Rabin Medical Center
Monosymptomatic Nocturnal Enuresis
Desmopressin Melt: Impact on Sleep and Daytime Functioning
Nocturnal enuresis affects 10% of the 7-year-old children and is essentially caused by a mismatch between nocturnal bladder capacity and the amount of urine produced during the night together with failure of the child to awaken…
- Trial name
- SLEEP (NCT01645475)
- Testing
- Desmopressin lyophilisate (Melt)
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent
Nocturnal Enuresis
Vitamin D Serum Levels in Monosymptomatic Enuretic and Non Enuretic Children
We are group of researchers interested in causes and management of nocturnal enuresis, we embarked on this research on 2020 and we reached promising results regarding the role of vitamin D serum level in etiology and management…
- Trial name
- NCT06243042
- Testing
- serum vitamin D, urine osmolality, Frequency volume chart
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Treatment of Non-monosymptomatic Nocturnal Enuresis
Efficacy of Mirabegron for Treatment of Non-monosymptomatic Nocturnal Enuresis in Children
This phase 3 clinical trial will compare use of individual treatment with mirabegron or desmopressin and their combination for treatment of non-monosymptomatic nocturnal enuresis in children
- Trial name
- NCT07398261
- Testing
- Mirabegron 25 MG
- Where
- Egypt
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Enuresis, Nocturnal
The Effect of Selecting Treatment With Desmopressin or Alarm to Children With Enuresis Based on Home Recordings.
The aim of this study is to investigate the importance of clinical characterization of children with monosymptomatic nocturnal enuresis (MNE) in order to improve treatment efficacy.
- Trial name
- DRYCHILD (NCT03389412)
- Testing
- Desmopressin, Conditional alarm
- Where
- 6 sites in Belgium, China and 2 more
- Volunteers
- 324 people
- Sponsor
- University of Aarhus
Nocturnal Enuresis
Biomarkers in Urine for Children With Monosymptomatic Nocturnal Enuresis and Nocturnal Polyuria
The aim of the study is to identify protein markers in relation to the enuresis related nocturnal polyuria by using mass spectrometry on nocturnal urine samples.
- Trial name
- NCT04049019
- Testing
- Urine collection through a collecting device (Uridome®) for maximum 1 week, Urine collection
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Primary Monosymptomatic Nocturnal Enuresis
Effectiveness of Individualized Pelvic Floor Muscle Rehabilitation in Addition to Standard Urotherapy and Alarm Therapy in Children With Primary Monosymptomatic Nocturnal Enuresis
This study will evaluate whether adding individualized pelvic floor muscle rehabilitation to standard urotherapy and alarm treatment improves bedwetting in children aged 5-18 years with primary monosymptomatic nocturnal enuresis.
- Trial name
- NCT07890194
- Testing
- Standard urotherapy, Alarm therapy, Standard urotherapy, Alarm therapy, Individualized pelvic floor muscle rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Nocturnal Enuresis in Children
New Treatment for Nocturnal Enuresis in Children
The aim of the study is to evaluate the role of sulbutiamine in treatment of monosymptomatic nocturnal enuresis in children by using it alone or as a combination therapy with tricyclic antidepressants (imipramine+sulbutiamine).
- Trial name
- NCT06497647
- Testing
- Sulbutiamine, Imipramine
- Where
- Egypt
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Sohag University
Enuresis, Nocturnal
The Behavioral Therapy for Primary Monosymptomatic Nocturnal Enuresis
A prospective randomized clinical study was conducted at Urology departments, faculties of medicine, Fayoum and Cairo Universities.
- Trial name
- NCT07015320
- Testing
- urotherapy, no intervention
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Primary Monosymptomatic Nocturnal Enuresis, Copeptin
Serum Copeptin as Biomarker for Diagnosis and Classification of Polyuric Primary Monosymptomatic Nocturnal Enuresis
Primary monosymptomatic nocturnal enuresis (PMNE) is one of the most common urinary system problems in childhood. The exact pathological mechanism has not been fully elucidated yet, but excessive nocturnal urination is considered…
- Trial name
- NCT07496541
- Testing
- copeptin levels in NP-PMNE, Testing the level of copeptin in patients with NNP-PMNE, Testing the level of copeptin in healthy children
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Nocturnal Enuresis
Treatment of Monosymptomatic Nocturnal Enuresis
A prospective randomized trial to study the effect of spinal magnetic stimulation versus posterior tibial neuromodulation in the treatment of monosymptomatic nocturnal enuresis.
- Trial name
- NCT05306639
- Testing
- Rehabilitation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- University of Alexandria
Primary Monosymptomatic Nocturnal Enuresis
Posterior Tibial Nerve Stimulation Vs Desmopressin In Children With Primary Monosymptomatic Nocturnal Enuresis
Nocturnal enuresis is a worldwide health problem frequently encountered in childhood . It affects 18 % of younger school- age children in Egypt.
- Trial name
- PTNS (NCT04545931)
- Testing
- Posterior tibial nerve stimulation, Desmopressin Acetate
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Primary Monosymptomatic Nocturnal Enuresis
Bedtime Device Restriction and Desmopressin in PMNE.
This randomized controlled trial will evaluate whether restricting bedtime digital-device use improves the response to desmopressin in children with primary monosymptomatic nocturnal enuresis.
- Trial name
- NCT07776977
- Testing
- Desmopressin, Bedtime digital-device restriction
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Al-Azhar University
Nocturnal Enuresis
Copeptin for Prediction of Treatment Response in Children With Monosymptomatic Nocturnal Enuresis (MEN).
Monosymptomatic nocturnal enuresis (MEN) is a common problem in children, affecting 7-10% of all 7 year olds. MEN is often leading to psychosocial problems because of its burden and stigmatism.
- Trial name
- COMEN (NCT02621736)
- Testing
- blood sampling
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- University Hospital, Basel, Switzerland
Nocturnal Enuresis, Nocturnal Enuresis in Children
Causes and Types of Nocturnal Enuresis in Children
Nocturnal enuresis, commonly known as bedwetting, is a frequent condition that affects many children and can have a significant impact on their self-esteem, social life, and family stress.
- Conditions
- Nocturnal Enuresis, Nocturnal Enuresis in Children, Primary Nocturnal Enuresis, Secondary Nocturnal Enuresis
- Trial name
- NCT07508111
- Volunteers
- 80 people
- Sponsor
- Assiut University
Primary Nocturnal Enuresis, Nocturnal Enuresis in Children
Effectiveness of Pelvic Floor Muscle Rehabilitation Combined With Desmopressin in Children With Primary Monosymptomatic Nocturnal Enuresis
The aim of this randomized controlled trial is to evaluate the effects of Structured Pelvic Floor Muscle Rehabilitation (SPFMR) in children with Primary Monosymptomatic Nocturnal Enuresis (PMNE) who are undergoing desmopressin…
- Trial name
- NCT06883851
- Testing
- Structured pelvic floor rehabilitation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bahçeşehir University
Enuresis, Nocturnal
Ginko Biloba Versus Desmopressin in Treatment of Children With Monosymptomatic Nocturnal Enuresis
Bedwetting among children is a common disorder, affecting 30% at age 4, 10% at age 6, 3% at age 12, and 1% at age.Untreated, the spontaneous cure rate is about 15% a year.
- Trial name
- NCT06772584
- Testing
- Desmopressin Acetate 0.2 mg Tablets, Ginkgobiloba
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Nocturnal Enuresis, Vitamin D Deficiency
Vitamin D Versus Desmopressin Versus Combination Therapy in Children With Primary Monosymptomatic Nocturnal Enuresis and Vitamin D Deficiency
This randomized clinical trial evaluated three treatment approaches for children aged 6 to 12 years who had primary monosymptomatic nocturnal enuresis (night-time bedwetting) and confirmed vitamin D deficiency.
- Trial name
- NCT07292753
- Testing
- Vitamin D, Desmopressin
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Nocturnal Enuresis
Clinical Values of Voiding Diary for Diagnosis and Treatment for Monosymptomatic Enuresis in Children
Nocturnal enuresis is common problem in children who are from 5 to 18 years old and do not spontaneously urinate at least 2 times a week for more than 3 months. It can lead to major distress for the children and their parents.
- Trial name
- NCT03199508
- Testing
- the 3-day voiding diary, the 7-day voiding diary
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Mao Jianhua