Clinical trials: Morality
Moral Distress
The Interplay Between Moral Distress, Moral Resilience, and Mental Health Outcomes Among Neonatal Care Providers
Due to highly specialized medical care neonatal care providers are faced with numerous responsibilities which makes neonatal care a particularly challenging and stressful work environment.
- Trial name
- MoD (NCT06836323)
- Where
- Switzerland
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Postoperative Respiratory Failure, Abdominal Surgery
Mechanical Power for Ventilatory Settings in Operating Room
Postoperative respiratory failure (PRF) is a dreaded complication that imposes a significant burden through unplanned admission to the ICU, post discharge disability and mortality.
- Conditions
- Postoperative Respiratory Failure, Abdominal Surgery, Postoperative Pulmonary Complications, Morality
- Trial name
- IMPROVEIII (NCT07620132)
- Testing
- Mechanical power-guided ventilatory strategy, Standard fixed ventilatory settings
- Volunteers
- 490 people
- Sponsor
- University Hospital, Montpellier
COVID-19, Infections
Defining COVID-19 Infection Severity on Presentation to Hospital
In the assessment of severity in coronavirus disease 2019 (COVID-19), the modified Brit_x0002_ish Thoracic Society (mBTS)，CURB65 et al.
- Conditions
- COVID-19, Infections, Morality, Death, Assisted
- Trial name
- NCT05677789
- Testing
- Medical observation, Supportive treatment (BSC), Intensive care management
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Fuzhou General Hospital
Sepsis, Septic Shock
Clinical Outcome Study of High-dose Meropenem in Sepsis and Septic Shock Patients
Sepsis and septic shock patients are considered to have a high risk of complications and death. Appropriate antimicrobial therapy plays an important role in determining outcomes in septic patients.
- Conditions
- Sepsis, Septic Shock, Critical Illness, Carbapenem
- Trial name
- NCT03344627
- Testing
- Meropenem standard dose, Meropenem high dose
- Where
- Thailand
- Volunteers
- 76 people
- Sponsor
- Mahidol University
Decision Making ,Shared, Leadership
Coaching Doctors and Nurses to Improve Ethical Decision-making in Team
Literature and a pilot study performed in 2019 indicate room for enhancing openness to discuss ethical sensitive issues within and between teams, and improving goal-oriented care and decision-making for the benefit of the patient…
- Conditions
- Decision Making ,Shared, Leadership, End of Life Communication, End of Life Decision Making
- Trial name
- CODE II (NCT07327450)
- Testing
- Usual Care Group, CODE II intervention
- Where
- Belgium
- Volunteers
- 360 people
- Sponsor
- University Hospital, Ghent
Family Witnessed Resuscitation, Empathy Education
VIDEO LEARNING FOR EMPATHY, ETHICS AND FAMILY WITNESSED RESUSCITATION
This clinical trial (randomized controlled experimental study) aims to learn about the effects of presenting the family-witnessed CPR process from a patient's perspective through 360° virtual reality and 2D video within…
- Conditions
- Family Witnessed Resuscitation, Empathy Education, Ethics Nursing, Education Nursing
- Trial name
- NCT07692568
- Testing
- 360 Degree Virtual Reality Video, 2D Standard Video
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Kocaeli Sağlık ve Teknoloji Üniversitesi
Burnout Syndrome
Burnout Syndrome in the Intensive Care Unit Before and During a Palliative Care Trial
One hundred ICU doctors, nurses and psychologists from 4 / 8 ICUs of the Greek group of the 28 European units participating in the EPIC stepped-wedge trial (ClinicalTrials.gov NCT06605079) will each complete the same four-part…
- Trial name
- BURNOUT-EPIC (NCT07069010)
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Athens
Childhood Vaccinations
Tailoring of Vaccine-Focused Messages: Moral Foundations
This study is the first phase of a trial examining decision making about vaccines. This phase tests the impact of targeted vaccine-focused health messages on vaccine beliefs held by parents of young children and pre-adolescents.
- Trial name
- NCT02851459
- Testing
- Baseline Survey, Pre-intervention Survey, Morally Congruent Message
- Where
- United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Emory University
Interstitial Lung Disease, Mechanical Ventilation
Mechanical Ventilation in Interstitial Lung Disease
To identify risk factors for mortality in patients with interstitial lung disease receiving mechanical ventilation.
- Conditions
- Interstitial Lung Disease, Mechanical Ventilation, Risk Factors, Morality
- Trial name
- NCT03416075
- Testing
- Mechanical ventilation
- Volunteers
- 94 people
- Sponsor
- Beijing Chao Yang Hospital
Pediatric Cancer
Video Inspired Discussions About Ethical Outcomes in Pediatrics
The goal of this clinical trial is to learn if the VIDEO-PEDS intervention works to improve Goals of Care communication between clinicians and parents of children with cancer.
- Trial name
- VIDEO-PEDS (NCT06786104)
- Testing
- VIDEO-PEDS, VIDEO-PEDS pilot, Focus Group
- Where
- 4 sites in United States
- Volunteers
- 567 people
- Sponsor
- Massachusetts General Hospital
Heart Failure, Morality
Optimized Peak VO2 in Predicting Advanced HF
The ability and timely selection of severe heart failure (HF) patients for cardiac transplantation and advanced HF therapy is challenging. Peak VO2 by cardiopulmonary exercise test (CPET) was used for transplant listing.
- Conditions
- Heart Failure, Morality, Transplant; Failure, Heart
- Trial name
- NCT05212649
- Testing
- cardiopulmonary exercise test
- Where
- Taiwan
- Volunteers
- 377 people
- Sponsor
- Chang Gung Memorial Hospital
Borderline Personality Disorder (BPD)
Neurobehavioral Mechanisms of Moral Reasoning: an EEG Study in Patients With Borderline Personality Disorder
We will investigate social cognition in patients with Borderline personality disorder (BPD) combined with electroencephalographic (EEG) measures.
- Trial name
- NCT07091409
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Older People, Care Dependency
Implementing the Transcultural Social-Ethical-Care Model -TEC-MED for Older People in the Mediterranean Basin
Implementation of the TEC-MED model of social and health care in the elderly population of the Mediterranean basin through a quasi-experimental trial.
- Conditions
- Older People, Care Dependency, Social Exclusion
- Trial name
- TEC-MED (NCT06184178)
- Testing
- Socio-health care
- Where
- Spain
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- REGINA ALLANDE CUSSO
Mindfulness Training in Nursing Students
Mindfulness Training to Promote Prosocial Tendencies in Nursing Students
Brief Summary This study aims to examine the effects of a six-week mindfulness training program on mindfulness, moral identity, and prosocial tendencies among undergraduate nursing students.
- Trial name
- NCT07896148
- Testing
- Mindfulness Training, Alternative Educational Workshop
- Where
- Iran
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Qom University of Medical Sciences
Moral Value Conflicts, Moral Distress
Genetic Counselors' Experiences of Moral Value Conflicts With Clients
This study will examine the experience of moral value conflicts among genetic counselors. Previous research has shown that value conflicts do exist among genetic counselors, but little is known about the nature or consequences of…
- Conditions
- Moral Value Conflicts, Moral Distress, Genetic Counseling
- Trial name
- NCT00360711
- Where
- United States
- Sponsor
- National Human Genome Research Institute (NHGRI)
PATİENT CARE, Intensive Care Unit
Surgical ICU Nurses' Attitudes on End-of-Life Care
This study aims to explore the attitudes and behaviors of nurses working in surgical intensive care units (ICUs) towards end-of-life care, alongside identifying the barriers they face in providing such care.
- Trial name
- NCT06285305
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Kilis 7 Aralik University
Burnout, Professional, Caregiver Exhaustion
Effect of Implementation of a Moral Case Delibration Meetings on the Prevalence of Burn-out Syndrome in the ICU
Burnout syndrome (BOS) has a high prevalence in critical care nurses and physicians. Both personal characteristics and work-related factors have been associated with BOS.
- Trial name
- MCDIC (NCT04442438)
- Testing
- Monthly moral case deliberation
- Where
- 2 sites in Netherlands
- Volunteers
- 435 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Posttraumatic Stress Disorder, Moral Injury
Pilot Study Testing a Web-Based Moral Elevation Intervention for Veterans With PTSD and Moral Injury
Given the prevalence of posttraumatic stress disorder (PTSD) and moral injury in combat Veterans and the limitations to current treatments, novel approaches are needed to target both PTSD and moral injury and directly impact…
- Trial name
- NCT03906240
- Testing
- Moral Elevation intervention
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- VA Office of Research and Development
Hypoxemia, Morality
Health Systems and Policy Contexts of Medical Oxygen
This is a mixed-methods program evaluation from a health systems and policy perspective, involving (i) stakeholder analysis, (ii) policy-implementation gap analysis, and (iii) comparative country case studies.
- Conditions
- Hypoxemia, Morality, Pneumonia
- Trial name
- MOXY-HSP (NCT06169514)
- Testing
- No intervention
- Where
- 6 sites in Cambodia, Laos and 4 more
- Volunteers
- 1 people
- Sponsor
- Murdoch Childrens Research Institute
Rare Diseases, Epidemiology
Verification of the Epidemiology and Mortality of Rare Diseases in Taiwan With Real-world Evidence
This study aims to explore the longitudinal incidence and prevalence trends of selected muscular and bone-related rare diseases, i.e., Familial Amyloidotic Polyneuropathy (FAP), Primary hyperoxaluria, Wilson's disease, Cystic…
- Conditions
- Rare Diseases, Epidemiology, Morbidity, Morality
- Trial name
- NCT05367115
- Testing
- longitudinal observational study
- Where
- Taiwan
- Volunteers
- 5,000 people
- Sponsor
- National Cheng-Kung University Hospital