Clinical trials: Morbidly Obese Patients, active
Morbid Obesity, Pregnancy
Induction of Labor in Morbidly Obese Patients
The goal of this randomized control trial is to compare different doses of Misoprostol (25 mcg vs 50 mcg) in induction of labor (IOL) in morbidly obese patients with BMI >40.
- Trial name
- NCT06199154
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- University of Maryland, Baltimore
Obesity Difficult Airway Airway Management
Videolaryngoscopes in the Morbidly Obese
This study will evaluate four videolaryngoscopes used for intubation of extremely obese (class 3 obesity) patients scheduled for bariatric surgery.
- Trial name
- NCT07787468
- Testing
- Airway management
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Uniwersytet Radomski im. Kazimierza Pułaskiego
Morbid Obesity
Interaction Between Head/Neck Position and C-MAC Blade Geometry on Videolaryngoscopic Intubation in Morbidly Obese Patients: A Randomized Controlled Trial
This study aims to explore the effect of head/neck position (sniffing vs ramped) and C-MAC blade geometry (MAC vs D-blade) on intubation in morbidly obese patients. The patients will be randomized into 4 groups: 1.
- Trial name
- C-MAC (NCT07636746)
- Testing
- Sniffing position and using MAC blade., Ramped position and MAC Blade, videolaryngoscopy
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Morbid Obesity in Cardiac Surgery Patients, Postoperative Respiratory Dysfunction
Prophylactic Use of APRV Before Extubation in Morbidly Obese Patients After Cardiac Surgery.
Morbidly obese patients undergoing open heart surgery are at increased risk of breathing problems after removal of the breathing tube due to reduced lung function and chest wall restriction following surgery.
- Conditions
- Morbid Obesity in Cardiac Surgery Patients, Postoperative Respiratory Dysfunction, Mechanical Ventilation Strategies
- Trial name
- APRV-OBESE-CS (NCT07409324)
- Testing
- Airway Pressure Release Ventilation (APRV), Conventional Lung-Protective Mechanical Ventilation
- Volunteers
- 180 people
- Sponsor
- Ain Shams University
Intratracheal Inbubation
Airway Scope vs GlideScope for Intubation in Obese Patients
This study compares the time required to complete intubation in obese patients (Body Mass Index 40 or greater) when using either the GlideScope or Airway Scope video laryngoscope device to help place the endotracheal tube.
- Trial name
- NCT07453563
- Testing
- Intubation with GlideScope, Intubation with Airway Scope
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of New Mexico
Gastric Insufflation
Determination of the Optimal Inspiratory Pressure to Decrease Incidence of Gastric Insufflation With Adequate Ventilation During Facemask Ventilation in Morbidly Obese Patients
The goal of this randomized clinical trial is to optimize the inspiratory pressure during facemask ventilation (FMV) in morbidly obese patients (BMI ≥40 kg/m²), to ensure adequate ventilation while minimizing the risk of gastric…
- Trial name
- NCT07480031
- Testing
- "Ultrasound-Guided Optimization of Inspiratory Pressure During Facemask Ventilation"
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Benha University
Morbid Obesity, Bariatric Surgery Candidate
Rivaroxaban Versus Enoxaparin for Prophylaxis of Venous Thromboembolism in Bariatric Surgery
Rivaroxaban versus enoxaparin for prophylaxis of venous thromboembolism in morbidly obese patients undergoing bariatric surgery: An open_label randomized controlled trial
- Trial name
- NCT06689241
- Testing
- Enoxaparin, rivaroxaban
- Where
- Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Alexandria University
ARDS, Human, Obesity, Morbid
Transpulmonary Pressure - Guided Mechanical Ventilation in Morbidly Obese ARDS Patients: a Feasibility Study.
The goal of this clinical trial is to test a personalized intervention aiming to optimize the mechanical ventilator settings in morbidly obese patients suffering from moderate to severe Acute Respiratory Distress Syndrome (ARDS).
- Trial name
- TGV-MOA (NCT06119516)
- Testing
- Esophageal pressure-guided strategy,
- Where
- 5 sites in France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Morbid Obesity, Anorectal Diseases
GLP-1 Receptor Agonists and Early Proctologic Effects in Morbid Obesity
Prospective observational cohort study evaluating the early proctologic effects of GLP-1 receptor agonist therapy in morbidly obese patients.
- Conditions
- Morbid Obesity, Anorectal Diseases, Drug-Related Side Effects and Adverse Reactions, Constipation
- Trial name
- GLP-PROCT (NCT07668765)
- Testing
- GLP-1 receptor agonist therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gazi University
Obesity, Bariatric Surgery
Opioid-Free Versus Opioid-Based Anesthesia in Bariatric
This study is designed as a prospective, randomized, controlled clinical trial. It will be conducted in the operating rooms of the University of Health Sciences, Diyarbakır Gazi Yaşargil Training and Research Hospital.
- Trial name
- NCT07105839
- Testing
- Intraoperative rescue analgesia, Intraoperative rescue analgesia:
- Volunteers
- 50 people
- Sponsor
- Siirt Training and Research Hospital
Bariatric Surgery Candidate, Lower Urinary Tract Symptoms
Prospective Data on Bariatric Surgery Effect on IPSS and LUTS
To establish a central database on clinical parameters for patients who has morbid obesity, which aiming at 1. to compare the results of those with or without receiving invasive bariatric treatment in Prince of Wales Hospital …
- Trial name
- NCT06464822
- Testing
- Bariatric Surgery
- Where
- Hong Kong
- Volunteers
- 5,000 people
- Sponsor
- Chinese University of Hong Kong
Deep Tracheal Extubation
High-Flow Nasal Oxygen-Assisted Deep Extubation Versus Awake Extubation in Morbidly Obese Patients
This prospective, randomized controlled trial aims to compare two methods of tracheal extubation after general anesthesia in adults with morbid obesity undergoing elective laparoscopic surgery.
- Trial name
- NCT07918885
- Testing
- HFNO-Assisted Deep Extubation, Conventional Awake Extubation
- Volunteers
- 120 people
- Sponsor
- Fayoum University
Bariatric Surgery, Bariatric Surgery Candidate
Effect of Transcutaneous Electrical Nerve Stimulation on PODD in Bariatric Surgery Patients
Researchers aim to evaluate impact of transcutaneous electric nerve stimulator on the incidence of postoperative diaphragmatic dysfunction in patients living with obesity undergoing bariatric surgery
- Trial name
- NCT07569705
- Testing
- Transcutaneous nerve stimulator
- Where
- 2 sites in Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Obesity, Morbid Obesity
The Effect of Cognitive Function Level in Morbidly Obese Patients
Obesity is a disease caused by many factors, such as lifestyle, eating habits, lack of physical activity, hormonal and genetic influences. These different factors make treatment planning difficult.
- Trial name
- NCT07032415
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Kocaeli City Hospital
Morbid Obesity, Hypertension
Prevention of Coronary Heart Disease in Morbidly Obese Patients
The changes in risks of developing coronary heart disease in patients with morbid obesity after different weight loss interventions have not been extensively studied.
- Conditions
- Morbid Obesity, Hypertension, Type 2 DM, Obstructive Sleep Apnea
- Trial name
- SphCor (NCT00626964)
- Testing
- Bariatric Surgery, Conservative Treatment:
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- The Hospital of Vestfold
Morbid Obesity
Effect of Oxalidine Combined with Reduced-opioid Anesthesia on Multimodal Analgesia in Morbidly Obese Patients Undergoing Bariatric Surgery
The goal of this study is to elucidate the efficacy and safety of oxelidine combined with oligopiate anesthesia for multi-modal analgesia in weight-loss surgery in morbidly obese patients, and to discover a new strategy for…
- Trial name
- NCT06712199
- Testing
- oxalidine
- Where
- China
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Yongtao Sun
Hypoxemia, Esophageal Cancer
Combination of COMBO Endoscopy Oropharyngeal Airway and HFNC Oxygenation in Sedated Gastrointestinal Endoscopy for Morbidly Obese Patients
Hypoxaemia during sedated gastrointestinal endoscopy exceeds 40 % in morbidly obese (BMI ≥ 35 kg m-²) patients. High-flow nasal cannula alone often fails because of persistent airway collapse.
- Conditions
- Hypoxemia, Esophageal Cancer, Morbidly Obese Patients, Gastric Cancer
- Trial name
- NCT07175155
- Testing
- COMBO Endoscopy Oropharyngeal Airway with High-Flow Nasal Cannula Oxygenation, High-Flow Nasal Cannula Oxygenation
- Where
- 5 sites in China
- Volunteers
- 410 people
- Sponsor
- Zhejiang University