Clinical trials: Mortality Risk Prediction
Ankle Brachial Index
Ankle Brachial Index Combined With Serum Uric Acid Levels Improve Prediction All Cause Mortality and Cardiovascular Mortality in the Elderly Chinese Population
Peripheral arterial disease (PAD) is a common clinical manifestation of the systemic atherosclerotic process, and the ankle brachial index (ABI) is an ideal tool to diagnose PAD.
- Trial name
- abilities (NCT03616418)
- Testing
- antiplatelet drugs;statins;antihypertensive drugs
- Volunteers
- 3,026 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Electrocardiogram, Mortality Risk Prediction
AI-ECG for One-Year Mortality Risk Prediction
Cardiovascular disease (CVD) remains one of the leading causes of death worldwide. While the electrocardiogram (ECG) is a standard, widely accessible tool for cardiovascular screening, traditional risk assessment models often…
- Trial name
- NCT07659262
- Testing
- Chang Gung ECG Mortality Risk Prediction Software (Model: CGMH-DRP-001)
- Where
- 3 sites in Taiwan
- Volunteers
- 461,982 people
- Sponsor
- National Defense Medical Center, Taiwan
Infective Endocarditis (IE)
European Research Group on Outcomes of Surgical Treatment of Infective Endocarditis
The European Research Group on Outcomes of Surgical Treatment of Infective Endocarditis (ERGOSTE) is a nascent large surgical registry that would encompass most relevant aspects of IE in Europe in the contemporary era.
- Trial name
- ERGOSTE (NCT07108803)
- Where
- Italy
- Volunteers
- 2,500 people
- Sponsor
- Azienda Sanitaria Universitaria Giuliano Isontina (ASU GI)
Cardiovascular Diseases, Cardiovascular Morbidity
Prediction of the Risks of Cardiovascular Mortality
Monitoring risks of cardiovascular diseases in working population (18 - 65 years old) by monitoring their BMI, ankle-brachial index with pulse wave velocity, cholesterol and glycemia.
- Conditions
- Cardiovascular Diseases, Cardiovascular Morbidity, Stroke, Embolism
- Trial name
- NCT06103448
- Testing
- Ankle-brachial index - system 100
- Where
- Czechia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Jan Evangelista Purkyne University
Trauma, Injury
Intermountain Risk Score and Trauma
The investigators hypothesize that a risk score composed of age, sex, and the components of commonly ordered laboratory panels will be predictive of mortality in trauma patients, and will help improve clinicians' ability to make…
- Trial name
- NCT02011412
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Intermountain Health Care, Inc.
Heart Failure, Heart Failure, Systolic
Predicting Heart Failure Outcomes With Biomarkers and Imaging
This study aims to develop a better model to predict one-year risk of death in patients with heart failure. We will test whether combining information from routine blood tests (like NT-proBNP) and heart scans (measuring features…
- Conditions
- Heart Failure, Heart Failure, Systolic, Heart Failure, Diastolic, Heart Failure With Reduced Ejection Fraction (HFrEF)
- Trial name
- BIOPHF (NCT07332520)
- Volunteers
- 4,000 people
- Sponsor
- Xinjiang Medical University
Death
Predicting Mortality in Kidney Transplant Recipients
Accurately predicting kidney recipient risk of death has a crucial interest because of the organ shortage, the need to optimize allograft allocation by identifying high-risk patients who may not benefit from a transplant and…
- Trial name
- mBox (NCT06531967)
- Testing
- No intervention
- Where
- 11 sites in United States, Belgium and 2 more
- Volunteers
- 13,000 people
- Sponsor
- Paris Translational Research Center for Organ Transplantation
Cardiogenic Shock, Cardiogenic Shock Acute
Prospective Validation of the STOPSHOCK Score - Artificial Intelligence Based Predictive Scoring System to Identify the Risk of Developing Cardiogenic Shock (CS) in Patients Suffering From Acute Coronary Syndrome (ACS)
Cardiogenic shock (CS) is a severe complication of acute coronary syndrome (ACS) with mortality approaching 50% despite the use of percutaneous mechanical circulatory support devices (pMCS).
- Conditions
- Cardiogenic Shock, Cardiogenic Shock Acute, Cardiogenic Shock Post Myocardial Infarction, Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)
- Trial name
- STOPSCHOCK (NCT07090382)
- Where
- Slovakia
- Volunteers
- 1,046 people
- Sponsor
- Premedix Academy
Mortality, Surgery
Mortality Score in Elderly Patients With Colon Cancer
CR-POSSUM is one of the most used surgical scores to predict mortality after colorectal surgery. Its main drawback is the requirement of intraoperative variables, whose collection is time-consuming and prevents from obtaining a…
- Conditions
- Mortality, Surgery, Colon Cancer
- Trial name
- MECC (NCT04538404)
- Testing
- Colon Surgery
- Where
- 2 sites in Italy
- Volunteers
- 385 people
- Sponsor
- University of Bologna
Acute Variceal Bleeding
Clinical Characteristics Analysis and Prediction Model Establishment of Fatal Esophageal and Gastric Variceal Bleeding
The purpose of this study is to analyze the clinical characteristics of patients with fatal acute variceal bleeding (AVB) and establish a mortality risk prediction model to identify patients at high risk of death after admission…
- Trial name
- NCT05613309
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Renmin Hospital of Wuhan University
Abdominal Surgery, Postoperative Complications
P-POSSUM for Outcomes After Abdominal Surgery
Postoperative complications after abdominal surgery can lead to prolonged recovery, intensive care admission, and death. The P-POSSUM score is a commonly used surgical risk prediction tool, but its performance may vary between…
- Conditions
- Abdominal Surgery, Postoperative Complications, Surgical Risk Prediction, Postoperative Mortality
- Trial name
- PPOSSUM-ABD (NCT07667764)
- Where
- Vietnam
- Volunteers
- 3,000 people
- Sponsor
- Bach Mai Hospital
Bicuspid Aortic Valve
Medtronic Transcatheter Aortic Valve Replacement (TAVR) Low Risk Bicuspid Study
The objective of the trial is to evaluate the procedural safety and efficacy of the Medtronic TAVR system in patients with bicuspid aortic anatomy and severe aortic stenosis at low risk for SAVR
- Trial name
- NCT03635424
- Testing
- Medtronic TAVR Systems
- Where
- 25 sites in United States
- Volunteers
- 150 people
- Sponsor
- Medtronic Cardiovascular
Abdominal Injuries, Wounds and Injuries
Predictors of In-Hospital Mortality in Severe Abdominal Trauma
Severe abdominal trauma is a leading cause of early death from bleeding and of later death from sepsis and organ failure. Clinicians use scoring systems to estimate the risk of dying, but most of these scores were developed and…
- Conditions
- Abdominal Injuries, Wounds and Injuries, Wounds, Nonpenetrating, Wounds, Penetrating
- Trial name
- NCT07843628
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Minia University
Oncology
Using Surveys to Examine the Association of Exposure to ML Mortality Risk Predictions With Medical Oncologists' Prognostic Accuracy and Decision-making
Nearly half of cancer patients in the US will receive care that is inconsistent with their wishes prior to death. Early advanced care planning (ACP) and palliative care improve goal-concordant care and symptoms and reduce…
- Trial name
- NCT06463977
- Testing
- Survey
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Mortality Prediction
Mortality Risk Assessment by Skilled Staff Compared to Existing Validated Tools in Skilled Nursing Departments
Mortality Risk Assessment by Skilled Caregivers Compared to Existing Validated Tools in Skilled Nursing Departments at Shmuel Harofeh Geriatric Hospital Background The elderly population in Israel and globally is growing…
- Trial name
- NCT06675071
- Volunteers
- 300 people
- Sponsor
- Shmuel Harofeh Hospital, Geriatric Medical Center
Stroke, Ischemic, Transient Ischemic Attack
TIA Scores' Mortality Predictions and Recurrent TIA and Stroke Prediction
Our study adopts a prospective design. Our research aims to determine the significance of ABCD2, ABCD3-I, Canadian TIA Score, and NIHSS Score in predicting the likelihood of ischemic stroke within 30 days in patients presenting…
- Trial name
- NCT06515392
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Saglik Bilimleri Universitesi
COPD
Predicting the Course of Chronic Obstructive Pulmonary Disease (COPD) in Primary Care
Background: COPD is a systemic illness; morbidity and mortality due to this disease are on the increase, and it has great impact on patients' lives. Most COPD patients are managed by general practitioners (GP).
- Trial name
- ICECOLDERIC (NCT00706602)
- Where
- Switzerland
- Volunteers
- 450 people
- Sponsor
- University of Zurich
Pre-operative, High-risk Patient
Practice Variation in Preoperative Multidisciplinary Team Discussions
Preoperative multidisciplinary team (MDT)discussions are recommended by national and international guidelines. However, no guidance is given on how to organise and execute an MDT discussion.
- Conditions
- Pre-operative, High-risk Patient, Frailty
- Trial name
- NCT05305053
- Testing
- preoperative MDT discussion
- Where
- 9 sites in Netherlands
- Volunteers
- 225 people
- Sponsor
- Rijnstate Hospital
Tricuspid Regurgitation
Tricuspid RegurgitAtion rIsk modeL Study (TRAIL Study)
This study is a multicenter cohort study including patients diagnosed with tricuspid regurgitation during hospitalization. The primary outcome of the study is all-cause death, and the secondary outcome is cardiovascular events.
- Trial name
- NCT06926959
- Where
- 7 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Sun Yat-sen University
Acute Ischemic Stroke
Construction and Validation of an In-hospital Mortality Risk Prediction Model for Acute Ischemic Stroke Patients
Firstly, the application effect of the existing predictive models, SOAR and GWTG-Stroke, was verified in Guangdong acute ischemic Stroke population, and the clinical application effect of the existing predictive models was…
- Trial name
- NCT04979624
- Volunteers
- 234 people
- Sponsor
- Shenzhen Second People's Hospital