Clinical trials: Motor Function
Cystic Fibrosis
Cystic Fibrosis and Endothelial Function: At Rest and During Exercise
Perhaps one of the most disturbing aspects of Cystic Fibrosis (CF) is the associated premature death. Oxidative stress has been observed in patients with CF and exercise intolerance has been shown to predict mortality in patients…
- Trial name
- NCT01772758
- Testing
- BH4 5mg, BH4 20mg, Antioxidant Cocktail
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Augusta University
Child Development, Upper Motor Neurone Lesion
Validity and Reliability of the PROprioception Measurement Tool (PROMT)
This project assesses the feasibility, reliability, and validity of the PROMT in children with a UMN lesion. The study questions are: is the newly developed PROMT a feasible, reliable, and valid tool to assess lower limb…
- Conditions
- Child Development, Upper Motor Neurone Lesion, Cerebral Palsy, Proprioceptive Disorders
- Trial name
- PROMT (NCT05405881)
- Testing
- Proprioception measurement tool
- Where
- Switzerland
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Rest, Training
The Effect of Cryostimulation on Inflammation and Motor Functions. The Study Was Conducted to Determine the Effect of Five Days of Whole-body Cryostimulation (PBC) on Reducing Inflammation and Improving Motor Skills in Soccer Players
The aim of the study was to determine the effect of a 5-day PBC on reducing inflammation and improving motor skills in soccer players during the initial phase of the training period.
- Trial name
- NCT06549933
- Testing
- Criostymulation
- Where
- Poland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Cardiovascular Disease, Aging
Effects of Exercise Training and AGE-crosslink Breaker on Cardiovascular Structure and Function
Healthy but sedentary aging leads to increased morbidity and mortality of cardiovascular disease. This is partly due to the accumulation of Advanced Glycation Endproducts (AGEs) and the stiffening of the myocardium and arteries.
- Conditions
- Cardiovascular Disease, Aging, Endothelial Dysfunction, Physical Activity
- Trial name
- NCT01417663
- Testing
- Alt-711, Physical exercise training
- Where
- Netherlands
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Fibromyalgia, Exercise
Cardiovascular Autonomic Function and Endogenous Pain Modulation
The study has three aims: 1. To investigate the influence of cardiovascular autonomic function on pain sensitivity at rest in patients with fibromyalgia and age- and sex-matched controls 2.
- Conditions
- Fibromyalgia, Exercise, Pain, Autonomic Dysfunction
- Trial name
- NCT03911609
- Testing
- Exercise, Cognitive Task
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Marquette University
Inflammatory Response, Metabolic Disturbance
Blueberries, Bananas, Exercise Recovery
The PURPOSE of this study is to investigate the combined influence of 2-weeks blueberry ingestion and banana ingestion (during exercise) on performance and in mitigating metabolic perturbation, immune dysfunction, and increase in…
- Conditions
- Inflammatory Response, Metabolic Disturbance, Immune Suppression
- Trial name
- NCT03445234
- Testing
- Blueberry, banana, No banana
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Sarcopenia
Sarcopenia and Combined-modality Exercise
This study examined the effects of combined-modality exercise training (resistance, endurance, flexibility and balance) on muscle mass, muscle function and physical activity in community-dwelling elderly living in Jamaica who had…
- Trial name
- NCT04806152
- Testing
- High intensity exercise, Usual care home exercise
- Where
- Jamaica
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Iron Deficiency
Effects of Iron Supplementation on Skeletal Muscle Properties in Females With Suboptimal Iron Storage
The goal of this clinical trial is to learn whether oral iron supplementation will increase skeletal muscle iron storage and its effects on exercise capacity in females with suboptimal iron status.
- Trial name
- MyoIRON (NCT07084298)
- Testing
- Oral iron supplement
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Parkinson Disease(PD)
Cycling and Treadmill With Dual Task for Parkinson's Disease Improvement
Motor impairment in lower extremities is common in individuals with Parkinson disease (PD). Development sensitive test for early motor deviations is important.
- Trial name
- NCT06355947
- Testing
- Cognitive cycling training, Cognitive treadmill training
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Spinal Cord Injury
Intermittent Hypoxia Elicits Prolonged Restoration of Motor Function in Human SCI
The goal of the study is to determine whether repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) will improve limb function after spinal cord injury.
- Trial name
- NCT01272349
- Testing
- Acute intermittent hypoxia, Room air
- Where
- 2 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Emory University
Urinary Incontinence (UI), Urinary Incontinence , Stress
Difference in Incontinence Prevalence Between High Impact Athletes, Low Impact Athletes and Sedentary Subjects
This observational cross-sectional study aims to investigate the association between participation in high-impact sports, physical activity level, and urinary incontinence in young adults.
- Trial name
- NCT07710508
- Testing
- No Intervention: Observational Cohort
- Where
- Spain
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Aging, Mobility Limitations
Life 2: Improving Fitness and Function in Elders
The purpose of this study is to determine whether a 12-month physical activity counseling program, compared to usual care, improves physical performance in a sample of older veterans.
- Trial name
- Project LIFE (NCT00435188)
- Testing
- Multi-component physical activity counseling program
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Temporomandibular Joint Dysfunction Syndrome
Effect of Progressive Neck Motor Control Exercises on Temporomandibular Joint Dysfunction
The primary aim of this study was to investigate the effects of progressive neck motor control exercises on craniocervical pain, posture, function and kinesiophobia in different types of temporomandibular dysfunction.
- Trial name
- NCT06148818
- Testing
- Progressive neck motor control exercise therapy, Patient education
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Child Development, Motor Skills
Classroom Exercise Snacks for Creativity, Motor Skills, and Academic Engagement in Elementary School Children
The purpose of this study is to evaluate whether brief, classroom-based exercise snacks (short bursts of physical activity performed during class time) can improve creativity, motor skills, and academic engagement in elementary…
- Conditions
- Child Development, Motor Skills, Executive Function
- Trial name
- ES-Kids (NCT07899242)
- Testing
- Classroom-Based Exercise Snacks
- Where
- Iran
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Abadan Branch
Fatigue
Measure of Fatigue in Functional MRI
The purpose of this study is to determine more objective, central and peripheral indices of fatigue state by exploring the neural and behavioral correlates of the alert process while keeping the idea to corroborate these results…
- Trial name
- FATIGUE (NCT02379013)
- Testing
- Volunteer with MRI
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Hôpital NOVO
Stroke, Stroke with Hemiparesis
Study of Hemodynamic Markers of Upper Extremity Motor Dysfunction in Stroke Patients Using Functional Near Infrared Spectroscopy (fNIRS)
The aim of the study was to explore potential pathways for recovery and adaptation of the motor cortex by examining cerebral blood flow characteristics and hemodynamic markers analyzed by functional near-infrared spectroscopy…
- Conditions
- Stroke, Stroke with Hemiparesis, Stroke, Ischemic
- Trial name
- NCT06806397
- Testing
- Stimulus response task
- Where
- 2 sites in Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skolkovo Institute of Science and Technology
Stroke
Motor Relearning Program and Aerobic Exercise in Postural Stability and Lower Limb Function in Subacute Stroke Patients
The aim of the study is to determine combined effects of MRP and aerobic exercise in postural stability and lower limb function in subacute stroke patients
- Trial name
- NCT06476782
- Testing
- Motor Relearning Program(MRP) and aerobic exercise, Motor Relearning Program(MRP)
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Healthy Aging, Cognitive Function 1, Social
Understanding Cerebral Blood Flow Dynamics for Alzheimer's Disease Prevention Through Exercise
Dementia is one of the leading causes of disability worldwide. Underlying biological mechanisms are crucial in preclinical stages of Alzheimer's disease (AD).
- Conditions
- Healthy Aging, Cognitive Function 1, Social, Cerebrovascular Circulation, Blood Flow
- Trial name
- flADex (NCT06584656)
- Testing
- Aerobic exercise condition, Resistance exercise condition
- Where
- 2 sites in Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
PreDiabetes, Pre Diabetes
Comparative Effects of High-Intensity Interval Training and Continuous Endurance Training Among Prediabetic Patients
Prediabetics is a condition where blood sugar levels are normal but not yet high enough to be diagnosed as type 2 diabetes. This phase offers a crucial point for timely intervention to delay or prevent type 2 diabetes.
- Conditions
- PreDiabetes, Pre Diabetes, Prediabetic State
- Trial name
- NCT07713030
- Testing
- High-Intensity Interval Training, Continuous Endurance Training
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Distal Hereditary Motor Neuropathy, Type II, Distal Hereditary Motor Neuropathy, Type V
Muscle Structure, Function and Gait in dHMN
Distal Hereditary Motor Neuropathy (dHMN) is a rare inherited neuromuscular disorder. It is characterised by distal weakness. The condition usually manifests in the second decade of life and progresses slowly.
- Conditions
- Distal Hereditary Motor Neuropathy, Type II, Distal Hereditary Motor Neuropathy, Type V, Distal Hereditary Motor Neuronopathy Type I, Distal Hereditary Motor Neuronopathy Type VI
- Trial name
- GAIT-dHMN (NCT04193228)
- Testing
- Carbon Fibre Ankle Foot Orthosis, Exercise
- Where
- United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University College London Hospitals
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