Clinical trials: Motor Function Disorders
Stroke, Rehabilitation
Effect of Hand Rehabilitation Robot on Acute Stroke
This study aimed to evaluate the effectiveness of hand robot-assisted therapy on functionality, fine motor skills, and activities of daily living (ADLs) in acute stroke rehabilitation.
- Trial name
- NCT06805955
- Testing
- NDT, NDT+Hand Robot
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Medipol University Hospital
Executive Function (Cognition), Soccer Training
Cognitive-Integrated Soccer Training and Performance
This study will examine whether an 8-week soccer-specific cognitive-motor training program can improve executive functions, decision-making, and soccer skill performance in youth soccer players.
- Conditions
- Executive Function (Cognition), Soccer Training, Performance, Motor Development
- Trial name
- NCT07284940
- Testing
- Cognitively Engaging Soccer Practice, Conventional Soccer Practice
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Fan Mao
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Type 2 Diabetes, Impaired Glucose Tolerance
Exercise Effects on Cardiovascular Risk Factors, Quality of Life, Muscle Function in Type 2 Diabetes and Healthy Persons
A sedentary lifestyle is known to be a risk factor to developing type 2 diabetes. The aim of this study was to determine the effects of adding regular Nordic walking to daily physical activity.
- Trial name
- SMIDIG (NCT00852982)
- Testing
- Exercise
- Where
- Sweden
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
ALSFTD, ALS (Amyotrophic Lateral Sclerosis)
Effects of Probiotics in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia Spectrum Disorder (ALS-FTDSD) Patients
The aim of this study is to assess the impact of a probiotic formulation on participants with ALS-FTDSD. It is hypothesized that participants given the probiotics will have different lipid profiles compared to participants…
- Conditions
- ALSFTD, ALS (Amyotrophic Lateral Sclerosis), Frontal Temporal Dementia (FTD)
- Trial name
- PROBIOTIC (NCT06051123)
- Testing
- Probiotic
- Where
- 3 sites in Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Stroke
Combined Effects of Tactile Kinesthetic Stimulation With Neural Mobilization in Stroke Patients
Combined Effects of Tactile -kinesthetic stimulation with Neural mobilization on sensory and motor functions of upper limb in stroke patients
- Trial name
- NCT07578961
- Testing
- Tactile kinesthetic stimulation with neural mobilization, kinesthetic therapy
- Where
- Pakistan
- Volunteers
- 53 people
- Sponsor
- Riphah International University
Rheumatoid Arthritis
SARAH Exercise Program in Patients With Rheumatoid Arthritis
The aim of this study is to investigate the effectiveness of the SARAH home exercise program to be applied for 12 weeks on wrist proprioception and hand functions in adult patients with rheumatoid arthritis.
- Trial name
- NCT05727488
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Izmir Katip Celebi University
Medulloblastoma, Childhood, Healthy Volunteers
Child's Study of the Impact of PF Lesion on Motor Skills, Language, Cognitive Functioning and Social Cognition
One of the major complications of posterior fossa surgery is Posterior Fossa Syndrome (PFS). This syndrome is due to a possible complication of surgical excision of a tumor of the cerebellum (4th ventricle) and is characterized…
- Conditions
- Medulloblastoma, Childhood, Healthy Volunteers, Fossa Posterior Tumor, Low-grade Glioma
- Trial name
- CervIRM (NCT04174820)
- Testing
- Functional Magnetic Resonance Imaging (fMRI)
- Where
- 5 sites in France
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Charcot-Marie-Tooth Disease Type 1A
Identification of Novel Biomarkers in Early Charcot-Marie-Tooth 1A Disease
This is a 2-year follow-up study of a cohort of 35 CMT1A patients and 20 healthy volunteers. The main objective is identifying prognostic markers for CMT1A using multi-omics analysis.
- Trial name
- CMT-MODS (NCT07049588)
- Testing
- Quantitative neuromuscular MRI, Skin biopsy, Clinical scores
- Where
- France
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Telerehabilitation
The Influence of Telerehabilitation Focused on Respiratory Muscle Training
Pulmonary rehabilitation, which includes respiratory muscle training, is effective in improving the functional status of patients with various types of the respiratory system diseases, including bronchial asthma, interstitial…
- Trial name
- NCT05533151
- Testing
- Respiratory muscle training
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Palacky University
HIV-Associated Cognitive Motor Complex
Mild Neurocognitive Disorder in HIV Infection of the Brain
Background: Some people with human immunodeficiency virus (HIV) develop problems with thinking and concentration when the virus affects the brain. This is known as mild neurocognitive disorder (MND).
- Trial name
- NCT01547754
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Spinal Muscular Atrophy
Study of the Functional Effects of Nusinersen in 5q-spinal Muscular Amyotrophy Adults (SMA Type 2 or 3 Forms)
Spinal Muscular Atrophy (SMA) is an autosomal recessive disease caused by a mutation of exon 7, in 95% of cases, encoding the gene for the motor neuron survival protein called SMN1 (Survival Motor Neuron) located on chromosome…
- Trial name
- NUSI-AD-5qSM (NCT04576494)
- Testing
- Monthly assessments of functional motor abilities by a trained therapist, Nusinersen
- Where
- France
- Volunteers
- 4 people
- Sponsor
- CHU de Reims
Brain Tumor
Use of Navigated Transcranial Magnetic Stimulation (nTMS) in Generated Motor and Language Mapping to Evaluate Brain Recovery Following Surgery
The goal of this clinical research study is to learn about using Navigated Transcranial Magnetic Stimulation (nTMS) in patients having surgery to remove a brain tumor in areas of the brain that control movement (motor function)…
- Trial name
- NCT02165995
- Testing
- Motor Mapping, Speech Mapping
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer, Locally Advanced Breast Cancer
Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer
This randomized, placebo-controlled trial aims to assess the feasibility, acceptability, and preliminary efficacy of memantine and the University of Carolina (UNC)'s Get Real \& Heel cancer exercise program (MEM+EX) in addressing…
- Conditions
- Breast Cancer, Locally Advanced Breast Cancer, Cognitive Impairment, Cognitive Decline
- Trial name
- NCT06727773
- Testing
- Memantine, Exercise Intervention, Exercise Control
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Autism
Motor Function Assessment and VR-based Motor Training in Adults With Autism Spectrum Disorder
The goal of this clinical trial is to learn if autism affect motor functions, including muscle strength, balance, and motor control? Additionally, understanding the motor functions, cognitive functions, and brain activation in…
- Trial name
- NCT07134569
- Testing
- VR-based motor training
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Bronchopulmonary Dysplasia, Necrotizing Enterocolitis
Effects of Delayed Cord Clamping in Very Low Birth Weight Infants
The purpose of this study was to see if a brief delay in cord clamping for 30 to 45 seconds would result in higher hematocrit levels, fewer transfusions, healthier lungs, and better motor function at 40 wks and 7 months of age.
- Conditions
- Bronchopulmonary Dysplasia, Necrotizing Enterocolitis, Intraventricular Hemorrhage, Late Onset Neonatal Sepsis
- Trial name
- NCT00840983
- Testing
- delayed cord clamping
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Rhode Island
Stroke, Stroke, Acute
The Effect of tDCS Combined With Functional Task Training on Motor Recovery in Stroke Patients
We propose to enhance the effects of brain plasticity using a powerful noninvasive technique for brain modulation consisting of navigated transcranial magnetic stimulation (TMS) priming with transcranial direct current…
- Conditions
- Stroke, Stroke, Acute, Motor Function
- Trial name
- NCT04646577
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Transcranial Direct Current Stimulation (tDCS
- Volunteers
- 40 people
- Sponsor
- King Fahad Specialist Hospital Dammam
Multiple Sclerosis, Physical Activity
The Effect of Physical Activity Levels on Dysmenorrhea Severity, Menstrual Symptoms, and Functional and Emotional Status in Women Diagnosed With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic, inflammatory, autoimmune disease that affects the central nervous system. It is more common in women, and hormonal factors are believed to play a role in its progression.
- Conditions
- Multiple Sclerosis, Physical Activity, Dysmenorrhea, Emotional Disorder
- Trial name
- NCT07011875
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Karabuk University
Multiple Sclerosis
Exercise in Multiple Sclerosis
Exercise therapy in MS patients has proven benefits on mobility, mood, motor function and quality of life. While the beneficial effects of exercise on cardiovascular and musculoskeletal function are well known, there has recently…
- Trial name
- NCT02716701
- Testing
- Exercise Group, Control Group, wristband activity tracker
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Minnesota
160 Participants Aged 18-35 Years and Obese (BMI ≥30) Open to Men and Women of All Ethnicity
Glycemic Load & Resistance Training on Endothelial Function & Insulin Sensitivity
This project is prompted by the urgent public health need to identify novel strategies to prevent cardiovascular disease (CVD) and type 2 diabetes (T2D).
- Trial name
- GET FIT (NCT01755962)
- Testing
- Glycemic Load, Resistance Training
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles