Clinical trials: Motor Recovery
Stroke
Perfetti Method in Upper Extremity of Stroke Patients
The cognitive sensory motor training therapy (Perfetti's technique) might be more effectiveness than conventional occupational therapy on upper extremity function recovery after acute stroke patients.
- Trial name
- NCT01374152
- Testing
- cognitive sensory motor training therapy
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Prasat Neurological Institute
Emotion Management Skills, Lifestyle, Healthy
The Impact of Enhanced Music & Natural Visuals on Emotional Health
The investigators are conducting research on factors related to the self-regulation of mood and arousal states across a range of everyday activities as well as different levels of stress.
- Conditions
- Emotion Management Skills, Lifestyle, Healthy, Lifestyle Intervention, Recovery
- Trial name
- NCT07676110
- Testing
- soundBrilliance software application - Emotional Health
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- soundBrilliance LLC
Healthy
Dual Site-Dual Channel Non-invasive Brain Stimulation for Motor Function in Healthy Subjects
The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of motor function in healthy subjects.
- Trial name
- NCT03486795
- Testing
- M1 stimulation, PMC stimulation
- Where
- South Korea
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Stroke, Spinal Cord Injuries (Complete and Incomplete)
EMG-Directed Virtual-Reality Training for Motor Stroke Rehabilitation
This study is testing whether rehabilitation using muscle activity signals can help improve arm and hand movement in people after stroke or spinal cord injury.
- Trial name
- NCT07705256
- Testing
- Visual EMG feedback with vibrotactile feedback, Visual EMG feedback
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Imperial College London
Stroke
A Novel Multimodal Approach to Promote Motor Recovery and Plasticity After Stroke
Upper extremity (UE) paresis or weakness is one of the most frequent impairments after stroke. Despite intense rehabilitation, motor and functional recovery of patients with severe hand impairments is poor.
- Trial name
- NCT07887880
- Testing
- tRNS (Transcranial Random Noise Stimulation), FES (Functional Electrical Stimulation)-assisted task-specific practice
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Utah
Physical Performance, Glucose
Timing of Broccoli Sprout Intake to Improve Exercise Performance
This study examines how the timing of intake of a broccoli sprout-based drink (a natural source of isothiocyanates, ITCs) affects physiological responses, recovery, and performance after a standardized endurance cycling session.
- Conditions
- Physical Performance, Glucose, Glycogen Metabolism, Lactate
- Trial name
- NCT07461194
- Testing
- Broccoli sprout drink (isothiocyanate-rich
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Swedish School of Sport and Health Sciences
Motor Recovery
BreEStim for Motor Recovery in Chronic Stroke With Severe Impairment (Pilot)
The overall goal is to investigate the effectiveness of a novel intervention - Breathing-controlled electrical stimulation (BreEStim) on finger flexor spasticity reduction and hand function improvement in chronic stroke with…
- Trial name
- NCT04750564
- Testing
- BreEStim, EStim
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center, Houston
Stroke, tDCS
Brain Stimulation Combined With Watching Hand Movements to Improve Hand Recovery in Chronic Stroke
This study investigates the neurophysiological mechanisms underlying the combined use of transcranial direct current stimulation (tDCS) and action observation therapy (AOT) for hand motor recovery in individuals with stroke.
- Conditions
- Stroke, tDCS, Action Observation Therapy, Hand
- Trial name
- NCT07400939
- Testing
- tDCS, Action Observation Therapy (AOT)
- Where
- 2 sites in Malaysia
- Volunteers
- 60 people
- Sponsor
- Universiti Malaysia Sabah
Sport Performance, Sport Recovery
Effects of Pulsed Electromagnetic Field Therapy on Sport Performance and Recovery
The goal of this clinical trial is to learn if pulsed electromagnetic field (PEMF) therapy works to improve sports performance and recovery in athletes.
- Conditions
- Sport Performance, Sport Recovery, Athlete
- Trial name
- NCT07288892
- Testing
- Active Pulsed Electromagnetic Field Therapy
- Where
- Singapore
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Stroke
Effect of an Electromagnetic Trainer on Gait and Balance Recovery After Stroke
This study aims to evaluate the effectiveness of an electromagnetic trainer in improving lower limb motor function, gait, and balance in patients after cerebral stroke.
- Trial name
- NCT07898657
- Testing
- Electromagnetic trainer, Standard medical rehabilitation
- Where
- 2 sites in Kazakhstan
- Volunteers
- 80 people
- Sponsor
- Karaganda Medical University
Thoracic Surgery
Surgical Prehabilitation on Autonomic Nervous System (TUNE)
This study will be a multicenter interventional randomized trial evaluating the effect of a multimodal prehabilitation program on heart rate variability (HRV).
- Trial name
- TUNE (NCT06398301)
- Testing
- Multimodal prehabilitation Program
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Università Vita-Salute San Raffaele
Spinal Cord Injuries, Motor Disorders
DiSCIoser: Improving Arm Sensorimotor Functions After Spinal Cord Injury Via Brain-Computer Interface Training
The goal of this clinical trial is to validate the efficacy of a Brain-Computer Interface (BCI)-based intervention for hand motor recovery in subacute cervical spinal cord injured (SCI) patients during rehabilitation.
- Trial name
- DiSCIoser (NCT05637775)
- Testing
- EEG-based BCI system for (hands) Motor Imagery training, Control - MI intervention
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Oxidative Stress, Physical Activity
Effect of the Combination of Pterostilbene Cocrystal With Silybin and Nicotinamide Riboside on Exercise-Induced Oxidative Stress
This study aims to evaluate the effects of the dietary supplement ccPT-SIL-NR, which contains pterostilbene (ccPT), silybin (SIL), and nicotinamide riboside (NR), on oxidative stress markers after a high-intensity exercise…
- Conditions
- Oxidative Stress, Physical Activity, Antioxidant Effect
- Trial name
- PT-SILAOX (NCT07024966)
- Testing
- Pterostilbene-silybin-nicotinamide riboside, Control Group
- Where
- Spain
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Chronic Stroke
Transcranial Direct Current Stimulation Combined Neuromuscular Electrical Stimulation on Motor Recovery in Stroke
The purpose of this study was to investigate the effects of the combination treatment strategy. A randomized, double-blinded and sham-stimulation study was conducted.
- Trial name
- NCT04059848
- Testing
- tDCS(Intelect Mobile Stimulation and Combination, DJO, France), NMES(Enraf Nonius, Endomed-182, Netherlands)
- Volunteers
- 30 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Concussion, Brain, Concussion, Mild
Mobile Subthreshold Exercise Program for Concussion--R01
Approximately 1.9 million youth sustain a concussion each year, and up to 30% experience persistent post-concussive symptoms (PPCS) such as headache, dizziness, and difficulty focusing that continue for weeks or months.
- Conditions
- Concussion, Brain, Concussion, Mild, Brain Injuries, Traumatic, Persistent Post Traumatic Headache
- Trial name
- MSTEP-R01 (NCT04688255)
- Testing
- MSTEP, Stretching
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Seattle Children's Hospital
Arthoplasty, Nutrition
Effects of Preoperative Whey Protein and Exercise Support on Recovery After Total Hip Arthroplasty
Objective: The aim of this project is to evaluate the effects of preoperative whey protein supplementation and a physical exercise program on postoperative recovery outcomes in patients undergoing total hip arthroplasty (THA).
- Conditions
- Arthoplasty, Nutrition, Geriatric Assessment, Exercise Training
- Trial name
- THA (NCT07329010)
- Testing
- Preoperative Whey Protein and Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- TC Erciyes University
Stroke, Cerebrovascular Accident
Fluoxetine Opens Window to Improve Motor Recovery After Stroke
The FLOW trial is a randomized placebo-controlled trial analyzing the effect of coupling an anti-depressant, fluoxetine (Prozac), and exercise to improve motor recovery following a stroke.
- Conditions
- Stroke, Cerebrovascular Accident, Cerebral Infarction, Brain Infarction
- Trial name
- FLOW (NCT03448159)
- Testing
- Fluoxetine Hydrochloride, Exercise Program
- Where
- 8 sites in Canada
- Volunteers
- 52 people
- Sponsor
- University Health Network, Toronto
Stroke, Stroke Hemorrhagic
Hand MOtor Rehabilitation Using a EMG-biofeedback: a Cross-sectional Study
Recovery of upper limb and hand gestures is fundamental for autonomy restoration after stroke. Innovative technologies are a valid support for the delivery of rehabilitation treatments.
- Conditions
- Stroke, Stroke Hemorrhagic, Stroke, Ischemic, Hemiparesis
- Trial name
- MORE (NCT04889586)
- Testing
- EMG-biofeedback armband (REMO)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Foot Drop, Charcot-Marie-Tooth Disease Type 1A
Muscle MRI Fat Fraction Before Surgery to Predict Strength Recovery After Foot-Drop Surgery in Charcot-Marie-Tooth Disease
The purpose of this prospective observational cohort study is to determine whether the amount of fat inside the donor muscles before surgery, measured with a magnetic resonance imaging (MRI) technique called Dixon fat fraction…
- Conditions
- Foot Drop, Charcot-Marie-Tooth Disease Type 1A, Charcot-Marie-Tooth Disease Type 2A, Charcot-Marie-Tooth Disease (CMT)
- Trial name
- CMT-FF-TPT (NCT07894536)
- Testing
- Tibialis posterior tendon transfer, Individualized adjunct procedures for cavovarus deformity correction, Ankle-foot orthosis (AFO)
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Stroke
Evaluation of the Effect of Dextro-Amphetamin Added to Physiotherapy in Patients After Stroke
The aim of the study is to evaluate the effect of Dextro-amphetamin added to physiotherapy on motor recovery in patients after stroke. The study is a double-blinded placebo-controlled randomised controlled trial.
- Trial name
- NCT00572767
- Testing
- Dextro-Amphetamin, Glucose
- Where
- Switzerland
- Volunteers
- 16 people
- Sponsor
- Reha Rheinfelden