Clinical trials: Motor Recovery
Acquired Brain Injuries, Spinal Cord Injury
Virtual Reality Rehabilitation for Cognitive, Emotional, and Motor Recovery in Neurological Disorders
This randomized controlled trial (RCT) evaluates the effectiveness of virtual reality (VR) rehabilitation in improving cognitive, emotional, social, and motor functions in patients with neurological disorders (ABI, SCI, MS, PD).
- Conditions
- Acquired Brain Injuries, Spinal Cord Injury, Multiple Sclerosis, Parkinson Disease
- Trial name
- NeuroVR (NCT06838975)
- Testing
- VR Training, traditional cognitive and motor rehabilitation following standard clinical practices
- Where
- 2 sites in Italy
- Volunteers
- 328 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis
Study to Investigate Vagus Nerve Stimulation Paired With Motor Task for Remyelination and Functional Recovery
The goal of this clinical trial is to learn if stimulating the vagus nerve in combination with a motor task in people with multiple sclerosis can improve motor function.
- Trial name
- NCT06641271
- Testing
- Closed Loop Trans-Auricular Vagus Nerve Stimulation System
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Colorado, Denver
Moderate to Severe Acute Ischaemic Stroke, Ischaemic Stroke
A Clinical Study to Investigate the Effect of Oral Neflamapimod on Motor Recovery After Acute Ischaemic Stroke
The purpose of this interventional study is to determine whether neflamapimod can improve residual physical disability and/or cognitive dysfunction after Moderate to Severe Acute Ischaemic Stroke.
- Trial name
- RESTORE (NCT06987643)
- Testing
- Neflamapimod
- Where
- 10 sites in Australia
- Volunteers
- 45 people
- Sponsor
- EIP Pharma Inc
Stroke, Stroke, Ischemic
Quantitative EEG Changes Following Repetitive Transcranial Magnetic Stimulation in Patients With Post Stroke (EEG-rTMS)
Quantitative EEG (qEEG) has been used as an effective tool in the diagnosis and prognosis of brain-related diseases. In the literature, a variety of qEEG parameters have been proven informative in the prognosis of stroke.
- Conditions
- Stroke, Stroke, Ischemic, Stroke/Brain Attack
- Trial name
- EEG-rTMS (NCT05657392)
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS), 32 electrode electroencephalography (EEG)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Izmir Katip Celebi University
Postpartum Period, Pelvic Floor
AfterBabyBodyStudy- Testing Manual Examination Methods and Exercise Effects on Muscular Recovery After Pregnancy
Exercising postpartum is important for the health of mother and child. However, there are physical changes postpartum which can prevent women from exercising postpartum.
- Conditions
- Postpartum Period, Pelvic Floor, Diastasis Recti, Exercise
- Trial name
- NCT03703804
- Where
- Sweden
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Arthroplasty, Replacement, Knee
Physical Activity Levels During Recovery Following Knee Arthroplasty
The goal of this study is to utilize physical activity monitoring to determine the trajectory of normal recovery as it relates to a patient's ability to get up and get moving.
- Trial name
- NCT04240769
- Testing
- Total or Partial Knee Arthroplasty
- Where
- United Kingdom
- Volunteers
- 400 people
- Sponsor
- University of Oxford
Motor Cortex; Lesion, Glioma
Accelerating Motor Recovering in Patients With SMA Syndrome After Glioma Surgery by Using nrTMS
The goal of this randomized clinical controlled trial is to learn about whether neuro-navigation repetitive transcranial magnetic stimulation (nrTMS) was useful to accelerate the recovery in patients with SMA syndrome after…
- Conditions
- Motor Cortex; Lesion, Glioma, Supplementary Motor Area Syndrome
- Trial name
- NCT05803057
- Testing
- TMS stimulation treatment
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Beijing Neurosurgical Institute
Basketball, Basketball Performance
Recovery Modalities and Application Sequence in Elite Female Basketball Players
The purpose of this study is to compare the effects of intermittent pneumatic compression, local heat, and mechanical vibration applications on recovery following high-intensity anaerobic exercise in elite female basketball…
- Conditions
- Basketball, Basketball Performance, Recovery, Recovery After Exercise
- Trial name
- NCT07899619
- Testing
- Intermittent Pneumatic Compression (IPC), Local Heat and Mechanical Vibration (Venom 2 Leg), Passive Rest
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medipol University
Stroke
Effect of tDCS on Brain Organization and Motor Recovery
Neurological deficits and motor disorders are extremely common after stroke. Physical therapies can improve the autonomy of these patients, but despite an intensive stationary neurorehabilitation, severe deficits often persist.
- Trial name
- ESTCORM (NCT03342534)
- Testing
- DC-stimulator (Neuroconn, Germany)
- Where
- 2 sites in Switzerland
- Volunteers
- 36 people
- Sponsor
- Adrian Guggisberg
Postpartum Pelvic Floor Dysfunction, Postpartum Urinary Incontinence
Exercise-Based Sensorimotor Physiotherapy for Postpartum Pelvic Health and Functional Recovery
This study evaluated whether a 12-week exercise-based sensorimotor physiotherapy program could improve pelvic health and functional recovery in postpartum women.
- Conditions
- Postpartum Pelvic Floor Dysfunction, Postpartum Urinary Incontinence, Postpartum Functional Recovery, Lumbopelvic Motor Control Impairment
- Trial name
- NCT07702565
- Testing
- Exercise-Based Sensorimotor Physiotherapy Program, Standard Postpartum Education and Home Advice
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Özge BAYKAN ÇOPUROĞLU
Stroke
Activity-based Mirror Therapy for Lower Limb Motor Recovery, Balance, Gait, and Mobility in Acute Inpatient Stroke: A Feasibility Study
This feasibility study is the first step of a larger effects study exploring the use of an activity-based mirror therapy program for people who have had a stroke in the last 30 days and are in the hospital.
- Trial name
- NCT06884709
- Testing
- Mirror Therapy
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- Glasgow Caledonian University
Brain Tumors, Transcranial Magnetic Stimulation
rTMS for Postoperative Brain Tumor Patients
When doctors perform surgery to remove brain tumors, the goal is to take out as much of the tumor as possible while keeping the patient's brain functions intact.
- Conditions
- Brain Tumors, Transcranial Magnetic Stimulation, Motor Deficit, Quality of Life
- Trial name
- NCT07530536
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Brian J.Gill
Stroke
Brain Network Models of Motor Recovery After Stroke
As with other real=world connected systems, studying the network structure of multiple interactions in the brain (holism versus reductionism) has profound implications in the comprehension of emergent complex phenomena like, for…
- Trial name
- ATTACK (NCT03784534)
- Testing
- Imaging, Clinical and behavioral testing : Motor recovery progress, Clinical and behavioral testing : Motor skills
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Stroke, Hemiparesis
Personalized Robotic Telerehabilitation for Upper Limb Functional Recovery After Stroke in a Home-Based Setting
Stroke is a leading cause of long-term disability worldwide, with upper-limb impairment representing a major determinant of functional limitation and reduced independence.
- Conditions
- Stroke, Hemiparesis, Upper Extremity Paresis, Motor Impairment
- Trial name
- ROBOHOME (NCT07590349)
- Testing
- Robotic-Assisted Telerehabilitation Virtual Reality-Based Telerehabilitation, Virtual reality-based rehabilitation platform without robotic assistance
- Volunteers
- 70 people
- Sponsor
- University of Campania Luigi Vanvitelli
Health Behavior
Cold Water Immersion in the Recovery of Markers of Muscle Damage of 10km Street Runners
Objective: To analyze the effect of cold water immersion (CWI) on the recovery of clinical, biochemical, functional and neuromuscular markers of muscle damage in 10 km street runners.
- Trial name
- NCT03094689
- Testing
- Cold water immersion, Water immersion
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Coronary Disease
Different Hydration Strategies Associated With Aerobic Exercise In Coronary
The need to restore water losses resulting from physical activity has become established and diffused into international consensus for healthy individuals or high-performance athletes.
- Trial name
- NCT04977258
- Testing
- Treadmill aerobic exercise without water intake, Treadmill aerobic exercise with water intake of a predetermined amount., Treadmill aerobic exercise with water intake according to the desire to drink
- Where
- Brazil
- Volunteers
- 31 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Whiplash Associated Disorders (WAD), Whiplash
Neuromuscular Mechanisms Underlying Poor Recovery From Whiplash Injuries
This study is investigating whether changes in the shape and size of bodily muscles and spinal cord anatomy can influence recovery rates following a motor vehicle collision (MVC).
- Trial name
- NCT02157038
- Testing
- Pedometer, MRI
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Northwestern University
Stroke Rehabilitation
Effects of Local Vibrations Program of Dorsiflexor Muscles on Neuromotor Recovery in Subacute Stroke Patients.
The aim of the vibration intervention proposed in the current study is to allow a better neuromotor recovery in subacute stroke patients when compared with standard rehabilitation alone.
- Trial name
- NEUROVIB-AVC (NCT05945212)
- Testing
- Vibration, 10 meters Walk Test, 2 Minute Walk Test (2MWT)
- Where
- 7 sites in France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Acute Ischemic Stroke
Temporal Interference Stimulation for Upper-Limb Motor Recovery in Early Subacute Stroke
This study aims to test whether transcranial temporal interference stimulation (tTIs) can improve upper limb motor function in patients in the early subacute stage after acute ischemic stroke.
- Trial name
- TIMES (NCT07896629)
- Testing
- Transcranial Temporal Interference Stimulation (tTIs)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xuanwu Hospital, Beijing
Underwater Electrical Stimulation
Effect of Underwater Electrical Stimulation on Hand Grip Strength in Stroke Patients
This study evaluates the therapeutic effects of underwater electrical faradic stimulation delivered via a four-cell hydrotherapy bath on hand grip strength and upper limb motor recovery in subacute post-stroke hemiplegic patients.
- Trial name
- NCT07794189
- Testing
- 4-cell Hydrotherapy Bath
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Deraya University