Clinical trials: Movement Abnormalities
Huntington Disease
Comparison Between [11C]UCB-J and [18F]SynVest-1 PET in HD.
Positron Emission Tomography (PET) is a functional imaging technique, which enables in vivo visualization of biological molecules expressed in human tissues.
- Trial name
- NCT05360082
- Testing
- [11C]UCB-J PET, [18F]SynVest-1 PET
- Where
- Belgium
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Parkinson's Disease
Systemic Synuclein Sampling Study (S4)
The purpose of this study is to measure alpha-synuclein in peripheral body tissues and fluids in Parkinson's disease (PD). This may help in developing better treatments for PD patients in the future.
- Trial name
- S4 (NCT02572713)
- Testing
- Biofluid samplings, Tissue samplings, DaTSCAN™
- Where
- 6 sites in United States, Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Michael J. Fox Foundation for Parkinson's Research
Movement, Abnormal, Lower Extremity Problem
Gluteal Activation Plus Movement Retraining
The purpose of this study is to determine if an isometric gluteal activation home exercise program (HEP) combined with a movement retraining program utilizing feedback cues produces significant changes in scores on the Forward…
- Trial name
- NCT07293039
- Testing
- Control HEP focusing on isometric gluteal activation, Experimental HEP focusing on isometric gluteal activation plus a movement retaining program
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Brain Diseases, Central Nervous System Diseases
Digital Diagnostics and Intervention Services for Parkinson's Disease
People with Parkinson's have infrequent clinical consultation (once every 12-18 months) and limited rehabilitation. Assessment play an important role in these consultations to help clinicians understand patients' health status…
- Conditions
- Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Joint Diseases
- Trial name
- NCT06534177
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Parkinson Disease
The Effects of Auditory Cues on Gait Mechanics in Parkinson's Disease
The purpose of this study is to determine how using auditory cues of a metronome and music at various frequencies impacts the gait mechanics in people with Parkinson's disease when walking over ground and on a treadmill.
- Trial name
- NCT03253965
- Testing
- Metronome Normal, Metronome Slow, Metronome Fast
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Tic Disorder, Tourette Syndrome
Role of the Sensory Experience in Generating Motor Tics in Tourette Syndrome
This study will investigate the sensation that many people with Tourette syndrome (TS) experience before they have a motor tic. It will also test whether blocking the sensation causes the tic to stop.
- Trial name
- NCT00755339
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Autism, Autism Spectrum Disorder
Comparing Imitation and Stereotyped Behaviors in Autistic Children: Robots vs. Human Operators
Virtual QT is a social robot designed to interact with humans in social and educational contexts. Equipped with visual and vocal interfaces, the robot can recognize and respond to various human inputs, providing emotional support…
- Trial name
- NCT06144528
- Testing
- QT robot
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Parkinson's Disease
Development of a Face Valid Executive Functioning Task
The purpose of this study is to develop a task to measure executive thinking skills that can be performed in a laboratory setting, but has clear parallels to the thinking demands of real life situations, and can be administered…
- Trial name
- MedTask (NCT00918112)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Parkinson Disease
Attending to External Cues and Movement Strategies in Parkinson Disease
People with Parkinson's disease use compensatory strategies to overcome typical gait disturbances. These strategies rely on attentional mechanisms, however people with Parkinson disease suffer of decline in cognitive function.
- Trial name
- NCT04674319
- Testing
- external cues and cogntive movement strategies
- Where
- Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Galit Yogev-Seligmann
Upper Extremity Dysfunction
Movement Enhancing Device for Children
The purpose of this study is to assess: 1) how infants move their bodies to explore, play, and solve problems, 2) if this is different in a high-risk group of infants, and 3) if these abilities can be advanced in a high-risk…
- Trial name
- NCT01959581
- Testing
- Movement Enhancing Device
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Parkinson Disease
The Effect of tDCS on a Motor-cognitive Dual-task Performance of Parkinson's Patients
The concurrent performance of two tasks, i.e., dual tasking (DT), is a common and ubiquitous every day phenomena. For example, people frequently walk while talking on a cellphone or drive while talking to a passenger.
- Trial name
- NCT02503930
- Testing
- Active tDCS
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Parkinson's Disease
Determination of Muscle Strength in Parkinsonian Patients Through the Use of an Isokinetic Dynamometer
Decreased muscle strength has been reported to be a factor contributing to increased incidences of falling in the elderly patients causing fractures, joint dislocations, severe soft tissue lesions and head trauma.
- Trial name
- CybexPD001 (NCT02101528)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini
Parkinson's Disease
Parkin Mutations and Their Functional Consequences
Parkinson's disease (PD) is the most frequent neurodegenerative disease with a prevalence of 2% over 65 years and because of this high prevalence as the population ages, it is a major problem of public health.
- Trial name
- NCT00136721
- Where
- France
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Parkinson Disease
Sleep Homeostasis in Parkinson's Disease
Parkinson's disease is characterized in the advanced phases by an altered response to dopaminergic therapy for the occurrence of abnormal movements called dyskinesias, that worsens the quality of life of the patient and exposes…
- Trial name
- NCT02200887
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Salvatore Galati
Parkinson Disease, Brain Tumor
Neuropsychology of Financial Capacity
The present project aims to investigate the financial capacity in patients diagnosed with Parkinson's Disease or parkinsonism, brain tumor (glioma or meningioma) and cerebrovascular lesion (stroke), in order to evaluate the…
- Conditions
- Parkinson Disease, Brain Tumor, Stroke
- Trial name
- NEUROFIN (NCT05791006)
- Testing
- Neuropsychological tests
- Where
- Italy
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Parkinson Disease
Identification of Risk Factors Parkinson's Disease by Convergence Strategy
Using this convergence approach from a limited group of subjects with non-diseased controls, patients with Parkinson's disease or related diseases, we will be able to limit the number of potential genes of specific susceptibility…
- Trial name
- CONVERGENCE (NCT03536104)
- Where
- France
- Volunteers
- 2,220 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Alzheimer's Disease (AD), Parkinson's Disease (PD)
Evaluation of [18F]MNI-777 PET as a Marker of Tau Pathology in Subjects With Tauopathies Compared to Healthy Subjects
The goal of this study is to assess [18F]MNI-777 PET imaging as a tool to detect tau pathology in the brain of individuals who carry a clinical diagnosis of a tauopathy, including: Alzheimer's Disease (AD),Parkinson's disease…
- Conditions
- Alzheimer's Disease (AD), Parkinson's Disease (PD), Chronic Traumatic Encephalopathy (CTE), Progressive Supranuclear Palsy (PSP)
- Trial name
- NCT02103894
- Testing
- [18F]T807 ([18F]MNI-777)
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Molecular NeuroImaging
Stroke, Able Bodied
Stimulation-Based Modulation of Spinal and Cortical Sensory Pathways
The goal of this study is to assess cervical (neck) reflexes by intra-operatively stimulating the neck nerve roots to evoke motor responses through their connections to spinal motoneurons.
- Trial name
- NCT07401186
- Testing
- Bipolar Neural Stimulation Electrode
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Peter C. Gerszten, MD
Parkinson Disease, Genetic Disease
The Epidemiology of Parkinson's Disease in Croatia and the Influence of Genetic Factors and Microbiota on the Progression and Treatment Outcomes of the Disease (GiOPARK)
Parkinson's disease (PD) is the second most common neurodegenerative disease, which affects 2-3% of the general population above 65 years.
- Conditions
- Parkinson Disease, Genetic Disease, Microbiota, Neuro-Degenerative Disease
- Trial name
- GiOPARK (NCT05008094)
- Testing
- Whole-exome sequencing, Microbiota sequencing, Magnetic resonance imaging
- Where
- Croatia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Center Rijeka
Parkinson Disease, Parkinson's Disease (PD)
Developing Immersive Gamification Technology Systems For The Rehabilitation Management Of Adults With Parkinson's Disease (Phase 1 Trial)
This clinical trial aims to develop and test a prototype immersive gamification technology system (ImGTS) among healthy volunteers and to determine its acceptability, safety, and usability in a healthy population.
- Trial name
- NCT07382401
- Testing
- VR-HMD, AR-HMD, semi-CAVE
- Where
- Philippines
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Augmented eXperience E-health Laboratory
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