Clinical trials: Movement Abnormalities
Essential Tremor
An Efficacy/Safety Study of Perampanel for Reducing Essential Tremor
Obtain information on whether the medication Perampanel reduces tremor in people with essential tremor and is well-tolerated.
- Trial name
- NCT02668146
- Testing
- Perampanel
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- VA Greater Los Angeles Healthcare System
Alzheimer Disease (AD), Frontotemporal Lobar Degeneration
ADDIA Proof-of-Performance Clinical Study
The objective of the ADDIA clinical Proof-of-Performance study is to validate the performance of ADDIA' blood biomarkers for diagnosis of Alzheimer's disease (AD).
- Conditions
- Alzheimer Disease (AD), Frontotemporal Lobar Degeneration, Dementia with Lewy Bodies (DLB), Parkinson Disease Dementia (PDD)
- Trial name
- ADDIA (NCT03030586)
- Testing
- volumetric MRI
- Where
- 13 sites in Belgium, France and 3 more
- Volunteers
- 821 people, healthy volunteers welcome
- Sponsor
- Amoneta Diagnostics SAS
Parkinson Disease
Effect of WB-EMS on Parkinson's Disease
The aim is to establish adequate and suitable protocols for PD patients and to determine the WB-EMS effects on muscle strength, balance, walking, cognitive functions,neurotrophic factors and alpha-synuclein.
- Trial name
- NCT04878679
- Testing
- Strenght training combined with WB-EMS, Cardiovascular training with WB-EMS, Control group
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Università degli studi di Roma Foro Italico
Falls, Balance
Postural Effects of Being Rotated in a Whole Body Gyroscope
Subjects will be secured and rotated in a whole body gyroscope, similar to a flight trainer for astronauts. The rotations will be in many directions and the speed will be at 90 deg/sec.
- Conditions
- Falls, Balance, Movement Disorders
- Trial name
- Gyro (NCT01188161)
- Testing
- Rotating Chair
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Carrick Institute for Graduate Studies
Parkinson Disease, Essential Tremor
Utilizing Smart Devices to Identify New Phenotypical Characteristics in Movement Disorders
This observational and experimental study seeks to establish a Smart Device System (SDS) to monitor high-resolution handtremor-based data using Smartphones, SmartWatches and Tablets.
- Conditions
- Parkinson Disease, Essential Tremor, Movement Disorders, Parkinson's Syndrome
- Trial name
- NCT03638479
- Testing
- Data Capture
- Where
- Germany
- Volunteers
- 513 people, healthy volunteers welcome
- Sponsor
- Universität Münster
Lewy Body Disease, Parkinson Disease Dementia
Learning to PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia
The investigators propose to adapt, improve, and implement a peer mentor support and caregiver education (PERSEVERE) program to improve LBD-specific caregiving mastery.
- Conditions
- Lewy Body Disease, Parkinson Disease Dementia, Dementia With Lewy Bodies
- Trial name
- NCT04649164
- Testing
- Peer mentor support and caregiver intervention, Focus group to provide feedback on educational materials and mentoring program
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Parkinson Disease
Development of Cognitive Assessment Tools in Parkinson Disease
The main objectives of this protocol are as follows: 1. To assess the sensitivity and specificity of ANAM-PD in detecting cognitive status in patients with Parkinson disease (PD) and healthy controls (HC). 2.
- Trial name
- ANAM (NCT00556764)
- Testing
- [123I] IBVM and SPECT imaging, Subjects will undergo the 123-I IBVM imaging visit
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Institute for Neurodegenerative Disorders
Parkinson Disease
Individualized Precise Localization of rTMS on Primary Motor Area
Parkinson's disease (PD) patients have some problem with self-initiated movement task. Compared with health controls, task meta-analysis found that PD patients showed abnormal activation in pre-supplementary motor area (pre-SMA)…
- Trial name
- NCT03497884
- Testing
- rTMS
- Where
- 2 sites in China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hangzhou Normal University
Parkinson Disease, Anxiety
MBCT for People With Parkinson's Disease and Caregivers
This study aims to explore the feasibility and effectiveness of mindfulness-based cognitive therapy (MBCT) in reducing anxiety and/or depressive symptoms in people with Parkinson's disease (PD) and caregivers of people with PD.
- Conditions
- Parkinson Disease, Anxiety, Depression
- Trial name
- MBCT-PD-2 (NCT04469049)
- Testing
- Mindfulness-based cognitive therapy (MBCT)
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Alzheimer Disease, Dementia
TapTalkTest Project:Development of a Non-invasive Screening Test to Detect Risk of Alzheimer's Disease Pathology
This project aims to produce a solution for the rising incidence of dementia. This is particularly pertinent in Tasmania, Australia, with a rapidly ageing population and the oldest demographics of all Australian states.
- Conditions
- Alzheimer Disease, Dementia, Movement Abnormalities, Speech Disorders
- Trial name
- TapTalkTest (NCT06114914)
- Testing
- Tap Talk online program
- Where
- Australia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Tasmania
Parkinson Disease
Somatotopy in Parkinson's Disease
This study aims to assess changes in connections within the brain in Parkinson's disease (PD). We will invite up to 10 people with PD to participate in this study and complete several brain scans using PET (Positron Emission…
- Trial name
- NCT04876404
- Testing
- PET/MR Imaging
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pacific Parkinson's Research Centre
Parkinson Disease
New Biomarkers in Parkinson's Disease
Parkinson's disease (PD) is the second most common neurodegenerative disease and its prevalence is expected to double over the next 30 years, making it a leading cause of neurological disability [GBD 2016 Neurology Collaborators…
- Trial name
- NCT05150158
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Parkinson Disease, Freezing of Gait
Motor Adaptation to Split-Belt Treadmill in Parkinson's Disease
Freezing of Gait (FOG) is a disabling symptom common in advanced Parkinson's Disease. FOG is an independent contributor to fall risk and is only partially relieved by medication.
- Trial name
- NCT03725215
- Testing
- Split-Belt Treadmill Training
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Parkinson's Disease and Parkinsonism
Caregiving in Advanced PD: A Tailored Support Group
The goal of this study is to understand how support groups can help people who care for individuals with Parkinson's Disease and Related Disorders (PDRD).
- Trial name
- NCT06074393
- Testing
- Tailored Support Group
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Parkinson's Disease
A Sequential Two-Part, Open-Label Study in Healthy Male and Female Subjects
An Open-Label Study in Healthy Male and Female Subjects to Identify the Concentration that Provides Optimal Bioavailability of Levodopa Infused Subcutaneously via a Pump System; and to Compare the Bioavailability of…
- Trial name
- NCT02604914
- Testing
- ND0612, LCIG
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NeuroDerm Ltd.
Dystonia, Primary, Dysarthria
Study of Speech Disorders , Voice and Swallowing in Primary Dystonia Oromandibular
To better define the clinical characteristics of oromandibular dystonia, we aimed to study voice, speech and swallowing disorders in idiopathic oromandibular We planned to include consecutive patients followed in Lille Movement…
- Conditions
- Dystonia, Primary, Dysarthria, Dysphonia, Dysphagia
- Trial name
- DOM (NCT03380676)
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Parkinson Disease
AI-PROGNOSIS - Digital Biomarkers Development Study (dBM-DEV)
dBM-dev study is a multicentre low-intervention research study which concerns REM sleep behaviour disorder (RBD) who is the best predictor for neurodegenerative diseases including Parkinson's disease (PD).
- Trial name
- dBM-DEV (NCT06444789)
- Testing
- connected smartwatch
- Where
- 4 sites in France, Germany and 2 more
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Alzheimer's Disease, Huntington Disease
A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine)
This study will evaluate four different modified release formulation to estimate the amount of dimebon available to the body relative to the current dimebon formulation that is given three times a day.
- Trial name
- NCT00988624
- Testing
- Dimebon IR Tablet, Dimebon MR1, Dimebon MR2
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pfizer
Functional Movement Disorder, Sport Injury
ASSESSMENT OF THE HANDBALL PLAYERS
''This study aims to determine the relationship between functional movement screen (FMS), core stabilization and Y balance test.
- Trial name
- NCT05861882
- Testing
- functional movement screen, survey application, Y balance test
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Parkinson's Disease
Cough According to Stimulus Type in PD
Aspiration pneumonia (APn) occurs at a higher rate in patients with Parkinson's disease (PD) versus healthy adults. This is of particular public health concern given that death secondary to aspiration pneumonia and lung infection…
- Trial name
- NCT02390089
- Testing
- Capsaicin vapor, fog, Videofluoroscopic swallow evaluation
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Florida
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